Citations for
1CRK, CRKL
Crk proteins transduce FGF signaling to promote lens fiber cell elongation.
Collins TN, Mao Y, Li H, Bouaziz M, Hong A, Feng GS, Wang F, Quilliam LA, Chen L, Park T, Curran T, Zhang X.
Elife 7. pii: e32586. doi: 10.7554/eLife.32586. 2018
2CRK, CRKL
Fibroblast Growth Requires CT10 Regulator of Kinase (Crk) and Crk-like (CrkL).
Park T, Koptyra M, Curran T.
J Biol Chem 291(51):26273-26290. Epub 2016 Nov 2. 2016
3CRK, CRKL
CRK proteins selectively regulate T cell migration into inflamed tissues.
Huang Y, Clarke F, Karimi M, Roy NH, Williamson EK, Okumura M, Mochizuki K, Chen EJ, Park TJ, Debes GF, Zhang Y, Curran T, Kambayashi T, Burkhardt JK.
J Clin Invest 125(3):1019-32. doi: 10.1172/JCI77278. Epub 2015 Jan 26. 2015
4CRK, CRKL
Essential roles of Crk and CrkL in fibroblast structure and motility.
Park TJ, Curran T.
Oncogene 33(43):5121-32. doi: 10.1038/onc.2013.453. Epub 2013 Oct 28. 2014
5CRK, MYO1C
Interaction of crk with Myosin-1c participates in fibronectin-induced cell spreading.
Oh H, Kim H, Shin B, Lee KH, Yeo MG, Song WK.
Int J Biol Sci 9(8):778-91. doi: 10.7150/ijbs.6459. eCollection 2013. 2013
6CRK
Overexpression of CRKII increases migration and invasive potential in oral squamous cell carcinoma.
Yamada S, Yanamoto S, Kawasaki G, Rokutanda S, Yonezawa H, Kawakita A, Nemoto TK.
Cancer Lett 303(2):84-91. Epub 2011 Feb 19. 2011
7CRK, CRKL
Identification of CrkL-SH3 binding proteins from embryonic murine brain: implications for Reelin signaling during brain development.
Cheerathodi M, Ballif BA.
J Proteome Res 10(10):4453-62. doi: 10.1021/pr200229a. Epub 2011 Sep 15. 2011
8AGRN, CRK, CRKL, DOK7, MUSK
Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L.
Hallock PT, Xu CF, Park TJ, Neubert TA, Curran T, Burden SJ.
Genes Dev 24(21):2451-61. 2010
9CRK, SOS1
Proteins that bind the Src homology 3 domain of CrkI have distinct roles in Crk transformation.
Zheng J, Machida K, Antoku S, Ng KY, Claffey KP, Mayer BJ.
Oncogene 29(48):6378-89. Epub 2010 Aug 23. 2010
10CRK, CRKL
Crk and Crk-like play essential overlapping roles downstream of disabled-1 in the Reelin pathway.
Park TJ, Curran T.
J Neurosci 28(50):13551-62.PMID: 19074029 2008
11CRK
v-Crk regulates membrane dynamics and Rac activation.
Yeo MG, Song WK.
Cell Adh Migr 2(3):174-6. Epub 2008 Jul 10. 2008
12CRK, CRKL
Proapoptotic function of the nuclear Crk II adaptor protein.
Kar B, Reichman CT, Singh S, O'Connor JP, Birge RB.
Biochemistry 46(38):10828-40. Epub 2007 Sep 1.PMID: 1776415 2007
13HGF, CRK
Adaptor molecule Crk is required for sustained phosphorylation of Grb2-associated binder 1 and hepatocyte growth factor-induced cell motility of human synovial sarcoma cell lines.
Watanabe T, Tsuda M, Makino Y, Ichihara S, Sawa H, Minami A, Mochizuki N, Nagashima K, Tanaka S.
Mol Cancer Res 4(7):499-510. 2006
14CRK, GIT2
GIT2 represses Crk- and Rac1-regulated cell spreading and Cdc42-mediated focal adhesion turnover.
Frank SR, Adelstein MR, Hansen SH.
EMBO J 25(9):1848-59. 2006
15CRK, LIS1, YWHAE, MDS, PAFAH1B1
Refinement of a 400-kb critical region allows genotypic differentiation between isolated lissencephaly, Miller-Dieker syndrome, and other phenotypes secondary to deletions of 17p13.3.
Cardoso C, Leventer RJ, Ward HL, Toyo-Oka K, Chung J, Gross A, Martin CL, Allanson J, Pilz DT, Olney AH, Mutchinick OM, Hirotsune S, Wynshaw-Boris A, Dobyns WB, Ledbetter DH.
Am J Hum Genet 72(4):918-30. Epub 2003 Mar 05. 2003
16CRK
Crk adapter proteins promote an epithelial-mesenchymal-like transition and are required for HGF-mediated cell spreading and breakdown of epithelial adherens junctions.
Lamorte L, Royal I, Naujokas M, Park M.
Mol Biol Cell 13(5):1449-61. 2002
17CRK, DOCK1, ELMO1, ELMO2, ELMO3, RAC1
CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.
Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS.
Cell 107(1):27-41. 2001
18CRK, HIC1
Physical and transcriptional mapping of the 17p13.3 region that is frequently deleted in human cancer.
Hoff C, Seranski P, Mollenhauer J, Korn B, Detzel T, Reinhardt R, Ramser J, Poustka A.
Genomics 70(1):26-33. 2000
19CRK, ABR, D17S34
Spatial organization of ABR and CRK genes on human chromosome band 17p13.3.
Morris C, et al.
Oncogene 10 : 1009-1011. 1995
20CRK
CRK proto-oncogene maps to human chromosome band 17p13.
Fioretos T, et al.
Oncogene 8 : 2853-2855. 1993
21CRK
Two species of human CRK cDNA encode proteins with distinct biological activities.
Matsuda M, Tanaka S, Nagata S, Kojima A, Kurata T, Shibuya M.
Mol Cell Biol 12(8):3482-9. 1992