| 1 | CRHR2, UCN2
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| Posttranslational processing of human and mouse urocortin 2: characterization and bioactivity of gene products.
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| Vaughan JM, Donaldson CJ, Fischer WH, Perrin MH, Rivier JE, Sawchenko PE, Vale WW.
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| Endocrinology 154(4):1553-64. doi: 10.1210/en.2012-2011. Epub 2013 Mar 14.
2013
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| 2 | CRHR1, CRHR2
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| Differential expression of CRH, UCN, CRHR1 and CRHR2 in eutopic and ectopic endometrium of women with endometriosis.
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| Vergetaki A, Jeschke U, Vrekoussis T, Taliouri E, Sabatini L, Papakonstanti EA, Makrigiannakis A.
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| PLoS One 8(4):e62313. doi: 10.1371/journal.pone.0062313. Print 2013.
2013
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| 3 | CRHR1, CRHR2
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| CRH-R1 and CRH-R2 differentially modulate dendritic outgrowth of hippocampal neurons.
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| Sheng H, Xu Y, Chen Y, Zhang Y, Xu X, He C, Ni X.
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| Endocrine 41(3):458-64. doi: 10.1007/s12020-012-9603-5. Epub 2012 Jan 17.
2012
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| 4 | CRHR2, DPYSL4
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| Activation of CRHR2 exerts an inhibitory effect on the expression of collapsin response mediator protein 3 in hippocampal neurons.
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| Chen Y, Sheng H, Xu Y, Zhang Y, Ni X.
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| Neuropeptides 46(2):93-8. doi: 10.1016/j.npep.2011.12.004. Epub 2012 Jan 14.
2012
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| 5 | CRHR2
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| Molecular determinants and feedback circuits regulating type 2 CRH receptor signal integration.
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| Markovic D, Punn A, Lehnert H, Grammatopoulos DK.
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| Biochim Biophys Acta 1813(5):896-907. doi: 10.1016/j.bbamcr.2011.02.005. Epub 2011 Feb 19.
2011
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| 6 | CRHR2
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| The pseudo signal peptide of the corticotropin-releasing factor receptor type 2a decreases receptor expression and prevents Gi-mediated inhibition of adenylyl cyclase activity.
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| Schulz K, Rutz C, Westendorf C, Ridelis I, Vogelbein S, Furkert J, Schmidt A, Wiesner B, Schülein R.
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| J Biol Chem 285(43):32878-87. doi: 10.1074/jbc.M110.129627. Epub 2010 Aug 3.
2010
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| 7 | CRHR2, UCN3
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| Urocortin 3 modulates social discrimination abilities via corticotropin-releasing hormone receptor type 2.
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| Deussing JM, Breu J, Kühne C, Kallnik M, Bunck M, Glasl L, Yen YC, Schmidt MV, Zurmühlen R, Vogl AM, Gailus-Durner V, Fuchs H, Hölter SM, Wotjak CT, Landgraf R, de Angelis MH, Holsboer F, Wurst W.
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| J Neurosci 30(27):9103-16. doi: 10.1523/JNEUROSCI.1049-10.2010.
2010
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| 8 | CRHR2
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| Activation of corticotropin-releasing factor receptor 2 inhibits the growth of human small cell lung carcinoma cells.
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| Wang J, Jin L, Chen J, Li S.
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| Cancer Invest 28(2):146-55. doi: 10.3109/07357900903179617.
2010
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| 9 | CRHR2
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| Activation of corticotropin-releasing factor 2 receptor inhibits Purkinje neuron P-type calcium currents via G(o)alpha-dependent PKC epsilon pathway.
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| Tao J, Zhang Y, Huang H, Jiang X.
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| Cell Signal 21(9):1436-43. doi: 10.1016/j.cellsig.2009.05.002. Epub 2009 May 9.
2009
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| 10 | CRHR2
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| Social defeat stress activates medial amygdala cells that express type 2 corticotropin-releasing factor receptor mRNA.
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| Fekete EM, Zhao Y, Li C, Sabino V, Vale WW, Zorrilla EP.
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| Neuroscience 162(1):5-13. doi: 10.1016/j.neuroscience.2009.03.078. Epub 2009 Apr 7.
2009
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| 11 | CRHR2
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| A novel corticotropin-releasing factor receptor splice variant exhibits dominant negative activity: a putative link to stress-induced heart disease.
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| Sztainberg Y, Kuperman Y, Issler O, Gil S, Vaughan J, Rivier J, Vale W, Chen A.
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| FASEB J 23(7):2186-96. doi: 10.1096/fj.08-128066. Epub 2009 Feb 26.
2009
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| 12 | UCN2, CRHR2
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| Urocortin2 inhibits tumor growth via effects on vascularization and cell proliferation.
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| Hao Z, Huang Y, Cleman J, Jovin IS, Vale WW, Bale TL, Giordano FJ.
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| Proc Natl Acad Sci U S A 105(10):3939-44. Epub 2008 Feb 28. 2008
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| 13 | CRHR1, CRHR2, HPGD
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| Corticotropin-releasing hormone receptor type 1 and type 2 mediate differential effects on 15-hydroxy prostaglandin dehydrogenase expression in cultured human chorion trophoblasts.
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| Gao L, He P, Sha J, Liu C, Dai L, Hui N, Ni X.
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| Endocrinology 148(8):3645-54. Epub 2007 Apr 26. 2007
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| 14 | CRHR1, CRHR2
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| Corticotropin-releasing hormone receptor (CRHR)1 and CRHR2 are both trafficking and signaling receptors for urocortin.
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| Tu H, Kastin AJ, Pan W.
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| Mol Endocrinol 21(3):700-11. Epub 2006 Dec 14.
2007
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| 15 | CRHR2, UCN2
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| Urocortin 2 modulates glucose utilization and insulin sensitivity in skeletal muscle.
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| Chen A, Brar B, Choi CS, Rousso D, Vaughan J, Kuperman Y, Kim SN, Donaldson C, Smith SM, Jamieson P, Li C, Nagy TR, Shulman GI, Lee KF, Vale W.
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| Proc Natl Acad Sci U S A 103(44):16580-5. Epub 2006 Oct 18. 2006
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| 16 | CRH, CRHR1, CRHR2
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| Corticotropin-releasing hormone activates ERK1/2 MAPK in specific brain areas.
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| Refojo D, Echenique C, Muller MB, Reul JM, Deussing JM, Wurst W, Sillaber I, Paez-Pereda M, Holsboer F, Arzt E.
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| Proc Natl Acad Sci U S A 102(17):6183-8. Epub 2005 Apr 15. 2005
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| 17 | UCN2, CRHR2
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| Urocortin 1 and Urocortin 2 induce macrophage apoptosis via CRFR2.
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| Tsatsanis C, Androulidaki A, Dermitzaki E, Charalampopoulos I, Spiess J, Gravanis A, Margioris AN.
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| FEBS Lett 579(20):4259-64. 2005
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| 18 | CRHR2
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| Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress.
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| Bale TL, Contarino A, Smith GW, Chan R, Gold LH, Sawchenko PE, Koob GF, Vale WW, Lee KF.
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| Nat Genet 24(4):410-4. 2000
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| 19 | CRHR2
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| Deletion of crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2.
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| Kishimoto T, Radulovic J, Radulovic M, Lin CR, Schrick C, Hooshmand F, Hermanson O, Rosenfeld MG, Spiess J.
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| Nat Genet 24(4):415-9. 2000
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| 20 | CRHR2
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| Localization of the human CRF2 receptor to 7p21-p15 by radiation hybrid mapping and FISH analysis.
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| Meyer AH, et al.
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| Genomics 40 : 189-190. 1997
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| 21 | CRHR2
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| A new functional isoform of the human CRF receptor for corticotropin-releasing factor.
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| Valdenaire O, Giller T, Breu V, Gottowik J, Kilpatrick G.
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| Biochim Biophys Acta 1352(2):129-32. 1997
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