1 | CREBBP, DYRK1A, EP300
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| DYRK1A interacts with histone acetyl transferase p300 and CBP and localizes to enhancers
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| Li S, Xu C, Fu Y, Lei PJ, Yao Y, Yang W, Zhang Y, Washburn MP, Florens L, Jaiswal M, Wu M, Mohan M.
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| Nucleic Acids Res. Nov 30;46(21):11202-11213. doi: 10.1093/nar/gky754. 2018
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2 | CREBBP, EP300, KMT2C, KMT2D
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| MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.
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| Lai B, Lee JE, Jang Y, Wang L, Peng W, Ge K.
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| Nucleic Acids Res 45(11):6388-6403. doi: 10.1093/nar/gkx234.
2017
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3 | CREBBP, GLI2, GLI3, PRKACA
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| Mutations of the Sonic Hedgehog Pathway Underlie Hypothalamic Hamartoma with Gelastic Epilepsy.
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| Hildebrand MS, Griffin NG, Damiano JA, Cops EJ, Burgess R, Ozturk E, Jones NC, Leventer RJ, Freeman JL, Harvey AS, Sadleir LG, Scheffer IE, Major H, Darbro BW, Allen AS, Goldstein DB, Kerrigan JF, Berkovic SF, Heinzen EL.
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| Am J Hum Genet 99(2):423-9. doi: 10.1016/j.ajhg.2016.05.031. Epub 2016 Jul 21.
2016
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4 | CREBBP, SMARCAD1
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| SMARCAD1 is an ATP-dependent stimulator of nucleosomal H2A acetylation via CBP, resulting in transcriptional regulation.
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| Doiguchi M, Nakagawa T, Imamura Y, Yoneda M, Higashi M, Kubota K, Yamashita S, Asahara H, Iida M, Fujii S, Ikura T, Liu Z, Nandu T, Kraus WL, Ueda H, Ito T.
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| Sci Rep 6:20179. doi: 10.1038/srep20179.
2016
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5 | CREBBP, EP300, TP53
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| Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
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| Krois AS, Ferreon JC, Martinez-Yamout MA, Dyson HJ, Wright PE.
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| Proc Natl Acad Sci U S A 113(13):E1853-62. doi: 10.1073/pnas.1602487113.
2016
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6 | CREBBP
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| Mutation of the CH1 Domain in the Histone Acetyltransferase CREBBP Results in Autism-Relevant Behaviors in Mice.
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| Zheng F, Kasper LH, Bedford DC, Lerach S, Teubner BJ, Brindle PK.
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| PLoS One 11(1):e0146366. doi: 10.1371/journal.pone.0146366.
2016
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7 | CREBBP, RSTS
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| Identification of a novel de novo mutation of CREBBP in a patient with Rubinstein-Taybi syndrome by targeted next-generation sequencing: a case report.
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| Kamenarova K, Simeonov E, Tzveova R, Dacheva D, Penkov M, Kremensky I, Perenovska P, Mitev V, Kaneva R.
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| Hum Pathol 47(1):144-9. doi: 10.1016/j.humpath.2015.09.004.
2016
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8 | AJUBA, CREBBP, PPARG
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| The LIM protein Ajuba promotes adipogenesis by enhancing PPARγ and p300/CBP interaction.
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| Li Q, Peng H, Fan H, Zou X, Liu Q, Zhang Y, Xu H, Chu Y, Wang C, Ayyanathan K, Rauscher FJ, Zhang K, Hou Z.
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| Cell Death Differ 23(1):158-68. doi: 10.1038/cdd.2015.83.
2016
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9 | CREBBP
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| The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.
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| Giotopoulos G, Chan WI, Horton SJ, Ruau D, Gallipoli P, Fowler A, Crawley C, Papaemmanuil E, Campbell PJ, Göttgens B, Van Deursen JM, Cole PA, Huntly BJ.
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| Oncogene 35(3):279-89. doi: 10.1038/onc.2015.92.
2016
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10 | CPSF4, CREBBP
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| CREB-binding protein regulates lung cancer growth by targeting MAPK and CPSF4 signaling pathway.
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| Tang Z, Yu W, Zhang C, Zhao S, Yu Z, Xiao X, Tang R, Xuan Y, Yang W, Hao J, Xu T, Zhang Q, Huang W, Deng W, Guo W.
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| Mol Oncol 10(2):317-29. doi: 10.1016/j.molonc.2015.10.015. Epub 2015 Nov 5.
2016
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11 | CREBBP, HIPK2
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| Complex regulation of CREB-binding protein by homeodomain-interacting protein kinase 2.
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| Kovács KA, Steinmann M, Halfon O, Magistretti PJ, Cardinaux JR.
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| Cell Signal 27(11):2252-60. doi: 10.1016/j.cellsig.2015.08.001. Epub 2015 Aug 4.
2015
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12 | CREBBP, TLX3
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| Tlx3 promotes glutamatergic neuronal subtype specification through direct interactions with the chromatin modifier CBP.
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| Shimomura A, Patel D, Wilson SM, Koehler KR, Khanna R, Hashino E.
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| PLoS One 10(8):e0135060. doi: 10.1371/journal.pone.0135060. 2015
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13 | CREBBP, PPP1R13L
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| A pro-apoptotic function of iASPP by stabilizing p300 and CBP through inhibition of BRMS1 E3 ubiquitin ligase activity.
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| Kramer D, Schön M, Bayerlová M, Bleckmann A, Schön MP, Zörnig M, Dobbelstein M.
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| Cell Death Dis 6:e1634. doi: 10.1038/cddis.2015.17.
2015
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14 | CREBBP, EP300, FOXP3
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| Two histone/protein acetyltransferases, CBP and p300, are indispensable for Foxp3+ T-regulatory cell development and function.
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| Liu Y, Wang L, Han R, Beier UH, Akimova T, Bhatti T, Xiao H, Cole PA, Brindle PK, Hancock WW.
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| Mol Cell Biol 34(21):3993-4007. doi: 10.1128/MCB.00919-14.
2014
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15 | CREBBP, KAT5
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| Regulation of CBP and Tip60 coordinates histone acetylation at local and global levels during Ras-induced transformation.
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| Sánchez-Molina S, Estarás C, Oliva JL, Akizu N, Asensio-Juan E, Rojas JM, Martínez-Balbás MA.
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| Carcinogenesis 35(10):2194-202. doi: 10.1093/carcin/bgu111.
2014
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16 | CREBBP, CTNNB1, TDG
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| Thymine DNA glycosylase promotes transactivation of β-catenin/TCFs by cooperating with CBP.
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| Jia Y, Nie F, Du A, Chen Z, Qin Y, Huang T, Song X, Li L.
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| J Mol Cell Biol 6(3):231-9. doi: 10.1093/jmcb/mju014. Epub 2014 Apr 18.
2014
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17 | EP300, MYB, cREBBP
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| Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.
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| Kasper LH, Fukuyama T, Lerach S, Chang Y, Xu W, Wu S, Boyd KL, Brindle PK.
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| PLoS One 8(12):e82684. doi: 10.1371/journal.pone.0082684.
2013
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18 | CREBBP, MYB
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| Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system.
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| Giri R, Morrone A, Toto A, Brunori M, Gianni S.
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| Proc Natl Acad Sci U S A 110(37):14942-7. doi: 10.1073/pnas.1307337110.
2013
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19 | CREBBP
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| The CH2 domain of CBP/p300 is a novel zinc finger.
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| Park S, Martinez-Yamout MA, Dyson HJ, Wright PE.
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| FEBS Lett 587(16):2506-11. doi: 10.1016/j.febslet.2013.06.051.
2013
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20 | CREBBP, EP300, STRA8
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| Distinct roles for CBP and p300 on the RA-mediated expression of the meiosis commitment gene Stra8 in mouse embryonic stem cells
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| Chen W, Jia W, Wang K, Si X, Zhu S, Duan T, Kang J.
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| PLoS One 2013 Jun 13;8(6):e66076. doi: 10.1371/journal.pone.0066076. 2013
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21 | CREBBP, DUP16P133
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| A microduplication of the Rubinstein-Taybi region on 16p13.3 in a girl with a bilateral complete cleft lip and palate and severe mental retardation.
|
| Tüysüz B, van Bon BW, Alp Z, Güzel Z, Veltman JA, de Vries BB.
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| Clin Dysmorphol 21(4):204-7. No abstract available.
2012
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22 | CREBBP, DUP16P133
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| Duplication 16p13.3 and the CREBBP gene: Confirmation of the phenotype.
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| Demeer B, Andrieux J, Receveur A, Morin G, Petit F, Julia S, Plessis G, Martin-Coignard D, Delobel B, Firth HV, Thuresson AC, Lanco Dosen S, Sjörs K, Le Caignec C, Devriendt K, Mathieu-Dramard M.
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| Eur J Med Genet ur J Med Genet. 2012 Oct 11. doi:pii: S1769-7212(12)00256-X. 10.1016/j.ejmg.2012.09.005. [Epub ahead of print]
2012
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23 | CREBBP, KDM3B, LMO2
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| KDM3B is the H3K9 demethylase involved in transcriptional activation of lmo2 in leukemia.
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| Kim JY, Kim KB, Eom GH, Choe N, Kee HJ, Son HJ, Oh ST, Kim DW, Pak JH, Baek HJ, Kook H, Hahn Y, Kook H, Chakravarti D, Seo SB.
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| Mol Cell Biol 32(14):2917-33. doi: 10.1128/MCB.00133-12. Epub 2012 May 21.
2012
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24 | CREBBP
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| Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity
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| Giralt A, Puigdellívol M, Carretón O, Paoletti P, Valero J, Parra-Damas A, Saura CA, Alberch J, Ginés S
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| Hum Mol Genet. Mar 15;21(6):1203-16. doi: 10.1093/hmg/ddr552. Epub 2011 Nov 24 2012
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25 | CREBBP, EP300
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| Inactivating mutations of acetyltransferase genes in B-cell lymphoma.
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| Pasqualucci L, Dominguez-Sola D, Chiarenza A, Fabbri G, Grunn A, Trifonov V, Kasper LH, Lerach S, Tang H, Ma J, Rossi D, Chadburn A, Murty VV, Mullighan CG, Gaidano G, Rabadan R, Brindle PK, Dalla-Favera R.
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| Nature 471(7337):189-95.
2011
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26 | CREBBP
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| CREBBP mutations in relapsed acute lymphoblastic leukaemia.
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| Mullighan CG, Zhang J, Kasper LH, Lerach S, Payne-Turner D, Phillips LA, Heatley SL, Holmfeldt L, Collins-Underwood JR, Ma J, Buetow KH, Pui CH, Baker SD, Brindle PK, Downing JR.
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| Nature 471(7337):235-9.
2011
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27 | CREBBP
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| CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.
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| Lopez-Atalaya JP, Ciccarelli A, Viosca J, Valor LM, Jimenez-Minchan M, Canals S, Giustetto M, Barco A.
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| EMBO J 30(20):4287-98. doi: 10.1038/emboj.2011.299.
2011
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28 | CREBBP, MAP3K4
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| MAP3K4/CBP-regulated H2B acetylation controls epithelial-mesenchymal transition in trophoblast stem cells.
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| Abell AN, Jordan NV, Huang W, Prat A, Midland AA, Johnson NL, Granger DA, Mieczkowski PA, Perou CM, Gomez SM, Li L, Johnson GL.
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| Cell Stem Cell 8(5):525-37. doi: 10.1016/j.stem.2011.03.008.
2011
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29 | CREBBP, DUP16P13, RSTS
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| Duplications of the critical Rubinstein-Taybi deletion region on chromosome 16p13.3 cause a novel recognisable syndrome.
|
| Thienpont B, Béna F, Breckpot J, Philip N, Menten B, Van Esch H, Scalais E, Salamone JM, Fong CT, Kussmann JL, Grange DK, Gorski JL, Zahir F, Yong SL, Morris MM, Gimelli S, Fryns JP, Mortier G, Friedman JM, Villard L, Bottani A, Vermeesch JR, Cheung SW, Devriendt K.
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| J Med Genet 47(3):155-61. Epub 2009 Oct 14.PMID: 19833603 2010
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30 | CREBBP, RSTS
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| High frequency of copy number imbalances in Rubinstein-Taybi patients negative to CREBBP mutational analysis.
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| Gervasini C, Mottadelli F, Ciccone R, Castronovo P, Milani D, Scarano G, Bedeschi MF, Belli S, Pilotta A, Selicorni A, Zuffardi O, Larizza L.
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| Eur J Hum Genet 18(7):768-75. Epub 2010 Feb 3.PMID: 20125191 2010
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31 | CREBBP, RSTS
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| Inheritance and variable expression in Rubinstein-Taybi syndrome.
|
| Bartsch O, Kress W, Kempf O, Lechno S, Haaf T, Zechner U.
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| Am J Med Genet A 152A(9):2254-61. 2010
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32 | CREBBP, DUP16P133
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| Duplications of the critical Rubinstein-Taybi deletion region on chromosome 16p13.3 cause a novel recognisable syndrome.
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| Thienpont B, Béna F, Breckpot J, Philip N, Menten B, Van Esch H, Scalais E, Salamone JM, Fong CT, Kussmann JL, Grange DK, Gorski JL, Zahir F, Yong SL, Morris MM, Gimelli S, Fryns JP, Mortier G, Friedman JM, Villard L, Bottani A, Vermeesch JR, Cheung SW, Devriendt K.
|
| J Med Genet 47(3):155-61. Epub 2009 Oct 14.
2010
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33 | CREBBP, EP300, RSTS, RSTS2
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| Somatic and germ-line mosaicism in Rubinstein-Taybi syndrome.
|
| Chiang PW, Lee NC, Chien N, Hwu WL, Spector E, Tsai AC.
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| Am J Med Genet A 149A(7):1463-1467. [Epub ahead of print] 2009
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34 | CREBBP, DUP16P13
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| Expanding the phenotype of duplication of the Rubinstein-Taybi region on 16p13.3.
|
| Dallapiccola B, Bernardini L, Novelli A, Mingarelli R.
|
| Am J Med Genet A m J Med Genet A. 2009 Nov 16. [Epub ahead of print] No abstract available. 2009
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35 | CREBBP, DEL16P133, DUP16P13
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| Duplications of the critical Rubinstein-Taybi deletion region on chromosome 16p13.3 cause a novel recognizable syndrome.
|
| Thienpont B, Béna F, Breckpot J, Philip N, Menten B, Van Esch H, Scalais E, Salamone J, Fong CT, Kussmann JL, Grange DK, Gorski J, Zahir F, Yong SL, Morris MM, Gimelli S, Fryns JP, Mortier G, Friedman JM, Villard L, Bottani A, Vermeesch JR, Cheung SW, Devriendt K.
|
| J Med Genet Med Genet. 2009 Oct 14. [Epub ahead of print] 2009
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36 | CREBBP, DUP16P133
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| Expanding the phenotype of duplication of the Rubinstein-Taybi region on 16p13.3.
|
| Dallapiccola B, Bernardini L, Novelli A, Mingarelli R.
|
| Am J Med Genet A 149A(12):2867-70. No abstract available.
2009
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37 | CREBBP, DUP16P133
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| Duplication of the Rubinstein-Taybi region on 16p13.3 is associated with a distinctive phenotype.
|
| Marangi G, Leuzzi V, Orteschi D, Grimaldi ME, Lecce R, Neri G, Zollino M.
|
| Am J Med Genet A 146A(18):2313-7.
2008
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38 | CREBBP, EP300, RSTS
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| Genotype-phenotype correlations in Rubinstein-Taybi syndrome.
|
| Schorry EK, Keddache M, Lanphear N, Rubinstein JH, Srodulski S, Fletcher D, Blough-Pfau RI, Grabowski GA.
|
| Am J Med Genet A 146A(19):2512-9.
2008
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39 | CREBBP
|
| CBP Is a dosage-dependent regulator of nuclear factor-kappaB suppression by the estrogen receptor.
|
| Nettles KW, Gil G, Nowak J, Métivier R, Sharma VB, Greene GL.
|
| Mol Endocrinol 22(2):263-72. Epub 2007 Oct 11.PMID: 17932106 2008
|
40 | CREBBP, EP300, KAT6A, NCOA2
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| Roles of the histone acetyltransferase monocytic leukemia zinc finger protein in normal and malignant hematopoiesis.
|
| Katsumoto T, Yoshida N, Kitabayashi I.
|
| Cancer Sci 99(8):1523-7. Review.PMID: 18754862 2008
|
41 | CREBBP, GATA2
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| CREB-binding proteins (CBP) as a transcriptional coactivator of GATA-2.
|
| Jiang H, Liu L, Yang S, Tomomi T, Toru N.
|
| Sci China C Life Sci 51(3):191-8.PMID: 18246306 2008
|
42 | CAMK4, CREBBP
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| Regulation of osteoclast differentiation and function by the CaMK-CREB pathway.
|
| Sato K, Suematsu A, Nakashima T, Takemoto-Kimura S, Aoki K, Morishita Y, Asahara H, Ohya K, Yamaguchi A, Takai T, Kodama T, Chatila TA, Bito H, Takayanagi H.
|
| Nat Med 12(12):1410-1416. Epub 2006 Nov 26. 2007
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43 | CREBBP
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| New types of MYST3-CBP and CBP-MYST3 fusion transcripts in t(8;16)(p11;p13) acute myeloid leukemias.
|
| Murati A, Adelaide J, Quilichini B, Remy V, Sainty D, Stoppa AM, Bernard P, Olschwang S, Birnbaum D, Chaffanet M, Mozziconacci MJ.
|
| Haematologica 92(2):262-3. 2007
|
44 | CREBBP, RSTS
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| High frequency of mosaic CREBBP deletions in Rubinstein-Taybi syndrome patients and mapping of somatic and germ-line breakpoints.
|
| Gervasini C, Castronovo P, Bentivegna A, Mottadelli F, Faravelli F, Giovannucci-Uzielli ML, Pessagno A, Lucci-Cordisco E, Pinto AM, Salviati L, Selicorni A, Tenconi R, Neri G, Larizza L.
|
| Genomics 90(5):567-73. Epub 2007 Sep 12. 2007
|
45 | CREBBP, DUP19P133
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| A microduplication of CBP in a patient with mental retardation and a congenital heart defect.
|
| Thienpont B, Breckpot J, Holvoet M, Vermeesch JR, Devriendt K.
|
| Am J Med Genet A 143A(18):2160-4.
2007
|
46 | CREBBP, DNASE1, RSTS
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| Evidence for a new contiguous gene syndrome, the chromosome 16p13.3 deletion syndrome alias severe Rubinstein-Taybi syndrome.
|
| Bartsch O, Rasi S, Delicado A, Dyack S, Neumann LM, Seemanova E, Volleth M, Haaf T, Kalscheuer VM.
|
| Hum Genet 120(2):179-86. Epub 2006 Jun 17. 2006
|
47 | RSTS, CREBBP
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| Rubinstein-Taybi syndrome.
|
| Hennekam RC.
|
| Eur J Hum Genet 14(9):981-5. Epub 2006 Jul 26. Review. 2006
|
48 | NCOA3, PPARG, CREBBP
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| Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program.
|
| Louet JF, Coste A, Amazit L, Tannour-Louet M, Wu RC, Tsai SY, Tsai MJ, Auwerx J, O'Malley BW.
|
| Proc Natl Acad Sci U S A 103(47):17868-73. Epub 2006 Nov 10. 2006
|
49 | CREBBP, RSTS
|
| Rubinstein-Taybi syndrome: molecular findings and therapeutic approaches to improve cognitive dysfunction.
|
| Hallam TM, Bourtchouladze R.
|
| Cell Mol Life Sci 63(15):1725-35. Review. 2006
|
50 | CREBBP, DUP16P133
|
| Oligonucleotide microarray analysis of genomic imbalance in children with mental retardation.
|
| Friedman JM, Baross A, Delaney AD, Ally A, Arbour L, Armstrong L, Asano J, Bailey DK, Barber S, Birch P, Brown-John M, Cao M, Chan S, Charest DL, Farnoud N, Fernandes N, Flibotte S, Go A, Gibson WT, Holt RA, Jones SJ, Kennedy GC, Krzywinski M, Langlois S, Li HI, McGillivray BC, Nayar T, Pugh TJ, Rajcan-Separovic E, Schein JE, Schnerch A, Siddiqui A, Van Allen MI, Wilson G, Yong SL, Zahir F, Eydoux P, Marra MA.
|
| Am J Hum Genet 79(3):500-13. Epub 2006 Jul 25. Erratum in: Am J Hum Genet. 2006 Dec;79(6):1135. Armstrong, Linlea [added].
2006
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51 | CREBBP, RSTS, EP300, RSTS2
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| Genetic Heterogeneity in Rubinstein-Taybi Syndrome: Mutations in Both the CBP and EP300 Genes Cause Disease.
|
| Roelfsema JH, White SJ, Ariyurek Y, Bartholdi D, Niedrist D, Papadia F, Bacino CA, den Dunnen JT, van Ommen GJ, Breuning MH, Hennekam RC, Peters DJ.
|
| Am J Hum Genet 76(4):572-80. Epub 2005 Feb 10. 2005
|
52 | BTRC, CREBBP, CSRP2, FKBP8, GAS1, GSK3B, HHAT, HHIP, IFT88, KIF27, KIF3A, KIF7, RAB23, SHH, STIL, STK36, SUFU, VTN
|
| Hedgehog signaling and congenital malformations.
|
| Nieuwenhuis E, Hui CC.
|
| Clin Genet 67(3):193-208. 2005
|
53 | CREBBP, RSTS
|
| DNA sequencing of CREBBP demonstrates mutations in 56% of patients with Rubinstein-Taybi syndrome (RSTS) and in another patient with incomplete RSTS.
|
| Bartsch O, Schmidt S, Richter M, Morlot S, Seemanova E, Wiebe G, Rasi S.
|
| Hum Genet 117(5):485-93. Epub 2005 Jul 14. 2005
|
54 | TRIP10, CREBBP, GAK, CNOT3, EIF2B1, SH3GL1, AP1B1
|
| Identification of novel CBP interacting proteins in embryonic orofacial tissue.
|
| Yin X, Warner DR, Roberts EA, Pisano MM, Greene RM.
|
| Biochem Biophys Res Commun 329(3):1010-7. 2005
|
55 | CREBBP, LAMA3
|
| CREB-binding protein regulates apoptosis and growth of HMECs grown in reconstituted ECM via laminin-5.
|
| Dietze EC, Bowie ML, Mrozek K, Caldwell LE, Neal C, Marjoram RJ, Troch MM, Bean GR, Yokoyama KK, Ibarra CA, Seewaldt VL.
|
| J Cell Sci 118(Pt 21):5005-22. Epub 2005 Oct 11. 2005
|
56 | CREBBP, SET
|
| The histone chaperone SET/TAF-Ibeta interacts functionally with the CREB-binding protein.
|
| Karetsou Z, Martic G, Sflomos G, Papamarcaki T.
|
| Biochem Biophys Res Commun 335(2):322-7. 2005
|
57 | CREBBP, CITED2, HIF1A
|
| Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites.
|
| De Guzman RN, Martinez-Yamout MA, Dyson HJ, Wright PE.
|
| J Biol Chem 279(4):3042-9. Epub 2003 Oct 31. 2004
|
58 | CREBBP, NCOA1, ETS2, TP53, IRF3, EP300
|
| A Conserved alpha-helical motif mediates the binding of diverse nuclear proteins to the SRC1 interaction domain of CBP.
|
| Matsuda S, Harries JC, Viskaduraki M, Troke PJ, Kindle KB, Ryan C, Heery DM.
|
| J Biol Chem 279(14):14055-64. Epub 2004 Jan 13. 2004
|
59 | CREBBP, IVL, KAT2B
|
| Regulation of the human involucrin gene promoter by co-activator proteins.
|
| Tran NQ, Crowe DL.
|
| Biochem J 381(Pt 1):267-73. 2004
|
60 | TCF3, CREBBP, HMCN1
|
| E2A-PBX1 interacts directly with the KIX domain of CBP/p300 in the induction of proliferation in primary hematopoietic cells.
|
| Bayly R, Chuen L, Currie RA, Hyndman BD, Casselman R, Blobel GA, LeBrun DP.
|
| J Biol Chem 279(53):55362-71. Epub 2004 Oct 26. 2004
|
61 | NLRP1, CREBBp
|
| NALP1 is a transcriptional target for cAMP-response-element-binding protein (CREB) in myeloid leukaemia cells.
|
| Sanz C, Calasanz MJ, Andreu E, Richard C, Prosper F, Fernandez-Luna JL.
|
| Biochem J 384(Pt 2):281-6. 2004
|
62 | CREBBP, RSTS
|
| Loss of CBP acetyltransferase activity by PHD finger mutations in Rubinstein-Taybi syndrome
|
| Kalkhoven E, Roelfsema JH, Teunissen H, den Boer A, Ariyurek Y, Zantema A, Breuning MH, Hennekam RC, Peters DJ.
|
| Hum Mol Genet 12(4):441-50. 2003
|
63 | CREBBP, KAT6B
|
| t(10;16)(q22;p13) and MORF-CREBBP fusion is a recurrent event in acute myeloid leukemia.
|
| Vizmanos JL, Larrayoz MJ, Lahortiga I, Floristan F, Alvarez C, Odero MD, Novo FJ, Calasanz MJ.
|
| Genes Chromosomes Cancer 36(4):402-5. 2003
|
64 | CREBBP, EP300
|
| Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.
|
| Tillinghast GW, Partee J, Albert P, Kelley JM, Burtow KH, Kelly K.
|
| Genes Chromosomes Cancer 37(2):121-31. 2003
|
65 | ATRX, CREBBP, DNMT3B, MECP2, RPS6KA3
|
| Syndromes of disordered chromatin remodeling.
|
| Ausio J, Levin DB, De Amorim GV, Bakker S, Macleod PM.
|
| Clin Genet 64(2):83-95. 2003
|
66 | CREBBP, EP300, SOX9
|
| Transcriptional co-activators CREB-binding protein and p300 regulate chondrocyte-specific gene expression via association with Sox9.
|
| Tsuda M, Takahashi S, Takahashi Y, Asahara H.
|
| J Biol Chem 278(29):27224-9. Epub 2003 May 5. 2003
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67 | CREBBP,SERTAD1
|
| Regulation of CREB-mediated transcription by association of CDK4 binding protein p34SEI-1 with CBP.
|
| Hirose T, Fujii R, Nakamura H, Aratani S, Fujita H, Nakazawa M, Nakamura K, Nishioka K, Nakajima T.
|
| Int J Mol Med 11(6):705-12. 2003
|
68 | CREBBP, HDAC1, NFKB1, NFKB2
|
| The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1.
|
| Zhong H, May MJ, Jimi E, Ghosh S.
|
| Mol Cell 9(3):625-36. 2002
|
69 | CREBBP, HLA-G
|
| HLA-G transactivation by cAMP-response element-binding protein (CREB). An alternative transactivation pathway to the conserved major histocompatibility complex (MHC) class I regulatory routes.
|
| Gobin SJ, Biesta P, de Steenwinkel JE, Datema G, van den Elsen PJ.
|
| J Biol Chem 277(42):39525-31. Epub 2002 Aug 14. 2002
|
70 | CREBBP, KAT6B
|
| Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13).
|
| Panagopoulos I, Fioretos T, Isaksson M, Samuelsson U, Billstrom R, Strombeck B, Mitelman F, Johansson B.
|
| Hum Mol Genet 10(4):395-404. 2001
|
71 | CREBBP
|
| Defect of histone acetyltransferase activity of the nuclear transcriptional coactivator CBP in Rubinstein-Taybi syndrome.
|
| Murata T, Kurokawa R, Krones A, Tatsumi K, Ishii M, Taki T, Masuno M, Ohashi H, Yanagisawa M, Rosenfeld MG, Glass CK, Hayashi Y.
|
| Hum Mol Genet 10(10):1071-6. 2001
|
72 | ATRX, CREBBP, DNMT3B, MECP2
|
| Human diseases with underlying defects in chromatin structure and modification.
|
| Hendrich B, Bickmore W.
|
| Hum Mol Genet 10(20):2233-42. 2001
|
73 | CREBBP, RSTS
|
| Variation in microdeletions of the cyclic AMP-responsive element-binding protein gene at chromosome band 16p13.3 in the rubinstein-taybi syndrome.
|
| Blough RI, Petrij F, Dauwerse JG, Milatovich-Cherry A, Weiss L, Saal HM, Rubinstein JH.
|
| Am J Med Genet 90(1):29-34 2000
|
74 | BRCA1, CREBBP, EP300
|
| CBP/p300 interact with and function as transcriptional coactivators of BRCA1.
|
| Pao GM, Janknecht R, Ruffner H, Hunter T, Verma IM.
|
| Proc Natl Acad Sci U S A 97(3):1020-5. 2000
|
75 | CREBBP, TNF
|
| A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor alpha gene expression.
|
| Falvo JV, Brinkman BM, Tsytsykova AV, Tsai EY, Yao TP, Kung AL, Goldfeld AE.
|
| Proc Natl Acad Sci U S A 97(8):3925-9. 2000
|
76 | CREBBP, HD, HTT, TP53
|
| The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
|
| Steffan JS, Kazantsev A, Spasic-Boskovic O, Greenwald M, Zhu YZ, Gohler H, Wanker EE, Bates GP, Housman DE, Thompson LM.
|
| Proc Natl Acad Sci U S A 97(12):6763-8. 2000
|
77 | CREBBP, PML
|
| Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling.
|
| Doucas V, et al.
|
| Proc Natl Acad Sci U S A 96(6):2627-2632. 1999
|
78 | AMLT3, CREBBP, KAT6A
|
| A case of inv(8)(p11q24) associated with acute myeloid leukemia involves the MOZ and CBP genes in a masked t(8;16).
|
| Chaffanet M, et al.
|
| Genes Chromosomes Cancer 26(2):161-165 1999
|
79 | CREBBP, RSTS
|
| FISH studies in 45 patients with Rubinstein-Taybi syndrome: deletions associated with polysplenia, hypoplastic left heart and death in infancy.
|
| Bartsch O, et al.
|
| Eur J Hum Genet 7(7):748-56 1999
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80 | CREBBP, RSTS
|
| Submicroscopic deletion of chromosome 16p13.3 in patients with Rubinstein-Taybi syndrome.
|
| Taine L, et al.
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| Am J Med Genet 78 : 267-270. 1998
|
81 | CREBBP, SMAD2, SMAD4
|
| CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor beta transcriptional responses in endothelial cells.
|
| Topper JN, et al.
|
| Proc Natl Acad Sci U S A 95 : 9506-9511. 1998
|
82 | CREBBP, EGR1
|
| cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1).
|
| Silverman ES, et al.
|
| Biochem J 336 : 183-189. 1998
|
83 | CREBBP, PML
|
| Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body.
|
| LaMorte VJ, et al.
|
| Proc Natl Acad Sci U S A 95(9):4991-6. 1998
|
84 | CREBBP, HIF1A
|
| Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha.
|
| Kallio PJ, Okamoto K, O'Brien S, Carrero P, Makino Y, Tanaka H, Poellinger L.
|
| EMBO J 17(22):6573-86 1998
|
85 | CREBBP
|
| Construction of 1.2-Mb contig surrounding, and molecular analysis of the human CREB-binding protein (CBP/CREBBP) gene on chromosome 16p13.3.
|
| Giles RH, Petrij F, Dauwerse HG, den Hollander AI, Lushnikova T, van Ommen GJ, Goodman RH, Deaven LL, Doggett NA, Peters DJ, Breuning MH.
|
| Genomics 42(1):96-114. 1997
|
86 | CREBBP, KMT2A
|
| The t(11;16)(q23;p13) translocation in myelodysplastic syndrome fuses the MLL gene to the CBP gene.
|
| Taki T, Sako M, Tsuchida M, Hayashi Y.
|
| Blood 89(11):3945-50. 1997
|
87 | CREBBP
|
| MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3).
|
| Sobulo OM, Borrow J, Tomek R, Reshmi S, Harden A, Schlegelberger B, Housman D, Doggett NA, Rowley JD, Zeleznik-Le NJ.
|
| Proc Natl Acad Sci U S A 94(16):8732-7. 1997
|
88 | CREBBP, KMT2A
|
| Novel MLL-CBP fusion transcript in therapy-related chronic myelomonocytic leukemia with a t(11;16)(q23;p13) chromosome translocation.
|
| Satake N, Ishida Y, Otoh Y, Hinohara S, Kobayashi H, Sakashita A, Maseki N, Kaneko Y.
|
| Genes Chromosomes Cancer 20(1):60-3. 1997
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89 | AMLT3, CREBBP, KAT6A
|
| Abnormalities of chromosome band 8p11 in leukemia : two clinical syndromes can be distinguished on the basis of MOZ involvement.
|
| Aguiar RC, Chase A, Coulthard S, Macdonald DH, Carapeti M, Reiter A, Sohal J, Lennard A, Goldman JM, Cross NC.
|
| Blood 90(8):3130-5. 1997
|
90 | CREBBP, STAT2
|
| Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha.
|
| Bhattacharya S, Eckner R, Grossman S, Oldread E, Arany Z, D'Andrea A, Livingston DM.
|
| Nature 383(6598):344-7 1996
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91 | CREBBP, HIF1A
|
| An essential role for p300/CBP in the cellular response to hypoxia.
|
| Arany Z, Huang LE, Eckner R, Bhattacharya S, Jiang C, Goldberg MA, Bunn HF, Livingston DM.
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| Proc Natl Acad Sci U S A 93(23):12969-73 1996
|
92 | AMLT3, CREBBP, KAT6A
|
| The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein.
|
| Borrow J, Stanton VP Jr, Andresen JM, Becher R, Behm FG, Chaganti RS,Civin CI, Disteche C, Dube I, Frischauf AM, Horsman D, Mitelman F, Volinia S,Watmore AE, Housman DE.
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| Nat Genet 14(1):33-41. 1996
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93 | CREBBP
|
| Localization of human CREB-binding protein gene (CREBBP) to 16p13.2-p13.3 by fluorescence in situ hybridization.
|
| Wydner KL, et al.
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| Genomics 30 : 395-396. 1995
|
94 | CREBBP
|
| Localization of human CREBBP (CREB Binding Protein) to 16p13.3 by fluorescence in situ hybridization.
|
| Chen XN, et al.
|
| Cytogenet Cell Genet 71 : 56-57. 1995
|
95 | EP300, CREBBP
|
| Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP.
|
| Lundblad JR, et al.
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| Nature 374 : 85-88. 1995
|
96 | RSTS, CREBBP
|
| Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP.
|
| Petrij F, et al.
|
| Nature 376 : 348-351. 1995
|
97 | CREBBP
|
| Phosphorylated CREB binds specifically to the nuclear protien CBP.
|
| Chrivia JC, et al.
|
| Nature 365 : 855-859. 1993
|