Citations for
1CREBBP, DYRK1A, EP300
DYRK1A interacts with histone acetyl transferase p300 and CBP and localizes to enhancers
Li S, Xu C, Fu Y, Lei PJ, Yao Y, Yang W, Zhang Y, Washburn MP, Florens L, Jaiswal M, Wu M, Mohan M.
Nucleic Acids Res. Nov 30;46(21):11202-11213. doi: 10.1093/nar/gky754. 2018
2CREBBP, EP300, KMT2C, KMT2D
MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.
Lai B, Lee JE, Jang Y, Wang L, Peng W, Ge K.
Nucleic Acids Res 45(11):6388-6403. doi: 10.1093/nar/gkx234. 2017
3CREBBP, GLI2, GLI3, PRKACA
Mutations of the Sonic Hedgehog Pathway Underlie Hypothalamic Hamartoma with Gelastic Epilepsy.
Hildebrand MS, Griffin NG, Damiano JA, Cops EJ, Burgess R, Ozturk E, Jones NC, Leventer RJ, Freeman JL, Harvey AS, Sadleir LG, Scheffer IE, Major H, Darbro BW, Allen AS, Goldstein DB, Kerrigan JF, Berkovic SF, Heinzen EL.
Am J Hum Genet 99(2):423-9. doi: 10.1016/j.ajhg.2016.05.031. Epub 2016 Jul 21. 2016
4CREBBP, SMARCAD1
SMARCAD1 is an ATP-dependent stimulator of nucleosomal H2A acetylation via CBP, resulting in transcriptional regulation.
Doiguchi M, Nakagawa T, Imamura Y, Yoneda M, Higashi M, Kubota K, Yamashita S, Asahara H, Iida M, Fujii S, Ikura T, Liu Z, Nandu T, Kraus WL, Ueda H, Ito T.
Sci Rep 6:20179. doi: 10.1038/srep20179. 2016
5CREBBP, EP300, TP53
Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
Krois AS, Ferreon JC, Martinez-Yamout MA, Dyson HJ, Wright PE.
Proc Natl Acad Sci U S A 113(13):E1853-62. doi: 10.1073/pnas.1602487113. 2016
6CREBBP
Mutation of the CH1 Domain in the Histone Acetyltransferase CREBBP Results in Autism-Relevant Behaviors in Mice.
Zheng F, Kasper LH, Bedford DC, Lerach S, Teubner BJ, Brindle PK.
PLoS One 11(1):e0146366. doi: 10.1371/journal.pone.0146366. 2016
7CREBBP, RSTS
Identification of a novel de novo mutation of CREBBP in a patient with Rubinstein-Taybi syndrome by targeted next-generation sequencing: a case report.
Kamenarova K, Simeonov E, Tzveova R, Dacheva D, Penkov M, Kremensky I, Perenovska P, Mitev V, Kaneva R.
Hum Pathol 47(1):144-9. doi: 10.1016/j.humpath.2015.09.004. 2016
8AJUBA, CREBBP, PPARG
The LIM protein Ajuba promotes adipogenesis by enhancing PPARγ and p300/CBP interaction.
Li Q, Peng H, Fan H, Zou X, Liu Q, Zhang Y, Xu H, Chu Y, Wang C, Ayyanathan K, Rauscher FJ, Zhang K, Hou Z.
Cell Death Differ 23(1):158-68. doi: 10.1038/cdd.2015.83. 2016
9CREBBP
The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.
Giotopoulos G, Chan WI, Horton SJ, Ruau D, Gallipoli P, Fowler A, Crawley C, Papaemmanuil E, Campbell PJ, Göttgens B, Van Deursen JM, Cole PA, Huntly BJ.
Oncogene 35(3):279-89. doi: 10.1038/onc.2015.92. 2016
10CPSF4, CREBBP
CREB-binding protein regulates lung cancer growth by targeting MAPK and CPSF4 signaling pathway.
Tang Z, Yu W, Zhang C, Zhao S, Yu Z, Xiao X, Tang R, Xuan Y, Yang W, Hao J, Xu T, Zhang Q, Huang W, Deng W, Guo W.
Mol Oncol 10(2):317-29. doi: 10.1016/j.molonc.2015.10.015. Epub 2015 Nov 5. 2016
11CREBBP, HIPK2
Complex regulation of CREB-binding protein by homeodomain-interacting protein kinase 2.
Kovács KA, Steinmann M, Halfon O, Magistretti PJ, Cardinaux JR.
Cell Signal 27(11):2252-60. doi: 10.1016/j.cellsig.2015.08.001. Epub 2015 Aug 4. 2015
12CREBBP, TLX3
Tlx3 promotes glutamatergic neuronal subtype specification through direct interactions with the chromatin modifier CBP.
Shimomura A, Patel D, Wilson SM, Koehler KR, Khanna R, Hashino E.
PLoS One 10(8):e0135060. doi: 10.1371/journal.pone.0135060. 2015
13CREBBP, PPP1R13L
A pro-apoptotic function of iASPP by stabilizing p300 and CBP through inhibition of BRMS1 E3 ubiquitin ligase activity.
Kramer D, Schön M, Bayerlová M, Bleckmann A, Schön MP, Zörnig M, Dobbelstein M.
Cell Death Dis 6:e1634. doi: 10.1038/cddis.2015.17. 2015
14CREBBP, EP300, FOXP3
Two histone/protein acetyltransferases, CBP and p300, are indispensable for Foxp3+ T-regulatory cell development and function.
Liu Y, Wang L, Han R, Beier UH, Akimova T, Bhatti T, Xiao H, Cole PA, Brindle PK, Hancock WW.
Mol Cell Biol 34(21):3993-4007. doi: 10.1128/MCB.00919-14. 2014
15CREBBP, KAT5
Regulation of CBP and Tip60 coordinates histone acetylation at local and global levels during Ras-induced transformation.
Sánchez-Molina S, Estarás C, Oliva JL, Akizu N, Asensio-Juan E, Rojas JM, Martínez-Balbás MA.
Carcinogenesis 35(10):2194-202. doi: 10.1093/carcin/bgu111. 2014
16CREBBP, CTNNB1, TDG
Thymine DNA glycosylase promotes transactivation of β-catenin/TCFs by cooperating with CBP.
Jia Y, Nie F, Du A, Chen Z, Qin Y, Huang T, Song X, Li L.
J Mol Cell Biol 6(3):231-9. doi: 10.1093/jmcb/mju014. Epub 2014 Apr 18. 2014
17EP300, MYB, cREBBP
Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.
Kasper LH, Fukuyama T, Lerach S, Chang Y, Xu W, Wu S, Boyd KL, Brindle PK.
PLoS One 8(12):e82684. doi: 10.1371/journal.pone.0082684. 2013
18CREBBP, MYB
Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system.
Giri R, Morrone A, Toto A, Brunori M, Gianni S.
Proc Natl Acad Sci U S A 110(37):14942-7. doi: 10.1073/pnas.1307337110. 2013
19CREBBP
The CH2 domain of CBP/p300 is a novel zinc finger.
Park S, Martinez-Yamout MA, Dyson HJ, Wright PE.
FEBS Lett 587(16):2506-11. doi: 10.1016/j.febslet.2013.06.051. 2013
20CREBBP, EP300, STRA8
Distinct roles for CBP and p300 on the RA-mediated expression of the meiosis commitment gene Stra8 in mouse embryonic stem cells
Chen W, Jia W, Wang K, Si X, Zhu S, Duan T, Kang J.
PLoS One 2013 Jun 13;8(6):e66076. doi: 10.1371/journal.pone.0066076. 2013
21CREBBP, DUP16P133
A microduplication of the Rubinstein-Taybi region on 16p13.3 in a girl with a bilateral complete cleft lip and palate and severe mental retardation.
Tüysüz B, van Bon BW, Alp Z, Güzel Z, Veltman JA, de Vries BB.
Clin Dysmorphol 21(4):204-7. No abstract available. 2012
22CREBBP, DUP16P133
Duplication 16p13.3 and the CREBBP gene: Confirmation of the phenotype.
Demeer B, Andrieux J, Receveur A, Morin G, Petit F, Julia S, Plessis G, Martin-Coignard D, Delobel B, Firth HV, Thuresson AC, Lanco Dosen S, Sjörs K, Le Caignec C, Devriendt K, Mathieu-Dramard M.
Eur J Med Genet ur J Med Genet. 2012 Oct 11. doi:pii: S1769-7212(12)00256-X. 10.1016/j.ejmg.2012.09.005. [Epub ahead of print] 2012
23CREBBP, KDM3B, LMO2
KDM3B is the H3K9 demethylase involved in transcriptional activation of lmo2 in leukemia.
Kim JY, Kim KB, Eom GH, Choe N, Kee HJ, Son HJ, Oh ST, Kim DW, Pak JH, Baek HJ, Kook H, Hahn Y, Kook H, Chakravarti D, Seo SB.
Mol Cell Biol 32(14):2917-33. doi: 10.1128/MCB.00133-12. Epub 2012 May 21. 2012
24CREBBP
Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity
Giralt A, Puigdellívol M, Carretón O, Paoletti P, Valero J, Parra-Damas A, Saura CA, Alberch J, Ginés S
Hum Mol Genet. Mar 15;21(6):1203-16. doi: 10.1093/hmg/ddr552. Epub 2011 Nov 24 2012
25CREBBP, EP300
Inactivating mutations of acetyltransferase genes in B-cell lymphoma.
Pasqualucci L, Dominguez-Sola D, Chiarenza A, Fabbri G, Grunn A, Trifonov V, Kasper LH, Lerach S, Tang H, Ma J, Rossi D, Chadburn A, Murty VV, Mullighan CG, Gaidano G, Rabadan R, Brindle PK, Dalla-Favera R.
Nature 471(7337):189-95. 2011
26CREBBP
CREBBP mutations in relapsed acute lymphoblastic leukaemia.
Mullighan CG, Zhang J, Kasper LH, Lerach S, Payne-Turner D, Phillips LA, Heatley SL, Holmfeldt L, Collins-Underwood JR, Ma J, Buetow KH, Pui CH, Baker SD, Brindle PK, Downing JR.
Nature 471(7337):235-9. 2011
27CREBBP
CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.
Lopez-Atalaya JP, Ciccarelli A, Viosca J, Valor LM, Jimenez-Minchan M, Canals S, Giustetto M, Barco A.
EMBO J 30(20):4287-98. doi: 10.1038/emboj.2011.299. 2011
28CREBBP, MAP3K4
MAP3K4/CBP-regulated H2B acetylation controls epithelial-mesenchymal transition in trophoblast stem cells.
Abell AN, Jordan NV, Huang W, Prat A, Midland AA, Johnson NL, Granger DA, Mieczkowski PA, Perou CM, Gomez SM, Li L, Johnson GL.
Cell Stem Cell 8(5):525-37. doi: 10.1016/j.stem.2011.03.008. 2011
29CREBBP, DUP16P13, RSTS
Duplications of the critical Rubinstein-Taybi deletion region on chromosome 16p13.3 cause a novel recognisable syndrome.
Thienpont B, Béna F, Breckpot J, Philip N, Menten B, Van Esch H, Scalais E, Salamone JM, Fong CT, Kussmann JL, Grange DK, Gorski JL, Zahir F, Yong SL, Morris MM, Gimelli S, Fryns JP, Mortier G, Friedman JM, Villard L, Bottani A, Vermeesch JR, Cheung SW, Devriendt K.
J Med Genet 47(3):155-61. Epub 2009 Oct 14.PMID: 19833603 2010
30CREBBP, RSTS
High frequency of copy number imbalances in Rubinstein-Taybi patients negative to CREBBP mutational analysis.
Gervasini C, Mottadelli F, Ciccone R, Castronovo P, Milani D, Scarano G, Bedeschi MF, Belli S, Pilotta A, Selicorni A, Zuffardi O, Larizza L.
Eur J Hum Genet 18(7):768-75. Epub 2010 Feb 3.PMID: 20125191 2010
31CREBBP, RSTS
Inheritance and variable expression in Rubinstein-Taybi syndrome.
Bartsch O, Kress W, Kempf O, Lechno S, Haaf T, Zechner U.
Am J Med Genet A 152A(9):2254-61. 2010
32CREBBP, DUP16P133
Duplications of the critical Rubinstein-Taybi deletion region on chromosome 16p13.3 cause a novel recognisable syndrome.
Thienpont B, Béna F, Breckpot J, Philip N, Menten B, Van Esch H, Scalais E, Salamone JM, Fong CT, Kussmann JL, Grange DK, Gorski JL, Zahir F, Yong SL, Morris MM, Gimelli S, Fryns JP, Mortier G, Friedman JM, Villard L, Bottani A, Vermeesch JR, Cheung SW, Devriendt K.
J Med Genet 47(3):155-61. Epub 2009 Oct 14. 2010
33CREBBP, EP300, RSTS, RSTS2
Somatic and germ-line mosaicism in Rubinstein-Taybi syndrome.
Chiang PW, Lee NC, Chien N, Hwu WL, Spector E, Tsai AC.
Am J Med Genet A 149A(7):1463-1467. [Epub ahead of print] 2009
34CREBBP, DUP16P13
Expanding the phenotype of duplication of the Rubinstein-Taybi region on 16p13.3.
Dallapiccola B, Bernardini L, Novelli A, Mingarelli R.
Am J Med Genet A m J Med Genet A. 2009 Nov 16. [Epub ahead of print] No abstract available. 2009
35CREBBP, DEL16P133, DUP16P13
Duplications of the critical Rubinstein-Taybi deletion region on chromosome 16p13.3 cause a novel recognizable syndrome.
Thienpont B, Béna F, Breckpot J, Philip N, Menten B, Van Esch H, Scalais E, Salamone J, Fong CT, Kussmann JL, Grange DK, Gorski J, Zahir F, Yong SL, Morris MM, Gimelli S, Fryns JP, Mortier G, Friedman JM, Villard L, Bottani A, Vermeesch JR, Cheung SW, Devriendt K.
J Med Genet Med Genet. 2009 Oct 14. [Epub ahead of print] 2009
36CREBBP, DUP16P133
Expanding the phenotype of duplication of the Rubinstein-Taybi region on 16p13.3.
Dallapiccola B, Bernardini L, Novelli A, Mingarelli R.
Am J Med Genet A 149A(12):2867-70. No abstract available. 2009
37CREBBP, DUP16P133
Duplication of the Rubinstein-Taybi region on 16p13.3 is associated with a distinctive phenotype.
Marangi G, Leuzzi V, Orteschi D, Grimaldi ME, Lecce R, Neri G, Zollino M.
Am J Med Genet A 146A(18):2313-7. 2008
38CREBBP, EP300, RSTS
Genotype-phenotype correlations in Rubinstein-Taybi syndrome.
Schorry EK, Keddache M, Lanphear N, Rubinstein JH, Srodulski S, Fletcher D, Blough-Pfau RI, Grabowski GA.
Am J Med Genet A 146A(19):2512-9. 2008
39CREBBP
CBP Is a dosage-dependent regulator of nuclear factor-kappaB suppression by the estrogen receptor.
Nettles KW, Gil G, Nowak J, Métivier R, Sharma VB, Greene GL.
Mol Endocrinol 22(2):263-72. Epub 2007 Oct 11.PMID: 17932106 2008
40CREBBP, EP300, KAT6A, NCOA2
Roles of the histone acetyltransferase monocytic leukemia zinc finger protein in normal and malignant hematopoiesis.
Katsumoto T, Yoshida N, Kitabayashi I.
Cancer Sci 99(8):1523-7. Review.PMID: 18754862 2008
41CREBBP, GATA2
CREB-binding proteins (CBP) as a transcriptional coactivator of GATA-2.
Jiang H, Liu L, Yang S, Tomomi T, Toru N.
Sci China C Life Sci 51(3):191-8.PMID: 18246306 2008
42CAMK4, CREBBP
Regulation of osteoclast differentiation and function by the CaMK-CREB pathway.
Sato K, Suematsu A, Nakashima T, Takemoto-Kimura S, Aoki K, Morishita Y, Asahara H, Ohya K, Yamaguchi A, Takai T, Kodama T, Chatila TA, Bito H, Takayanagi H.
Nat Med 12(12):1410-1416. Epub 2006 Nov 26. 2007
43CREBBP
New types of MYST3-CBP and CBP-MYST3 fusion transcripts in t(8;16)(p11;p13) acute myeloid leukemias.
Murati A, Adelaide J, Quilichini B, Remy V, Sainty D, Stoppa AM, Bernard P, Olschwang S, Birnbaum D, Chaffanet M, Mozziconacci MJ.
Haematologica 92(2):262-3. 2007
44CREBBP, RSTS
High frequency of mosaic CREBBP deletions in Rubinstein-Taybi syndrome patients and mapping of somatic and germ-line breakpoints.
Gervasini C, Castronovo P, Bentivegna A, Mottadelli F, Faravelli F, Giovannucci-Uzielli ML, Pessagno A, Lucci-Cordisco E, Pinto AM, Salviati L, Selicorni A, Tenconi R, Neri G, Larizza L.
Genomics 90(5):567-73. Epub 2007 Sep 12. 2007
45CREBBP, DUP19P133
A microduplication of CBP in a patient with mental retardation and a congenital heart defect.
Thienpont B, Breckpot J, Holvoet M, Vermeesch JR, Devriendt K.
Am J Med Genet A 143A(18):2160-4. 2007
46CREBBP, DNASE1, RSTS
Evidence for a new contiguous gene syndrome, the chromosome 16p13.3 deletion syndrome alias severe Rubinstein-Taybi syndrome.
Bartsch O, Rasi S, Delicado A, Dyack S, Neumann LM, Seemanova E, Volleth M, Haaf T, Kalscheuer VM.
Hum Genet 120(2):179-86. Epub 2006 Jun 17. 2006
47RSTS, CREBBP
Rubinstein-Taybi syndrome.
Hennekam RC.
Eur J Hum Genet 14(9):981-5. Epub 2006 Jul 26. Review. 2006
48NCOA3, PPARG, CREBBP
Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program.
Louet JF, Coste A, Amazit L, Tannour-Louet M, Wu RC, Tsai SY, Tsai MJ, Auwerx J, O'Malley BW.
Proc Natl Acad Sci U S A 103(47):17868-73. Epub 2006 Nov 10. 2006
49CREBBP, RSTS
Rubinstein-Taybi syndrome: molecular findings and therapeutic approaches to improve cognitive dysfunction.
Hallam TM, Bourtchouladze R.
Cell Mol Life Sci 63(15):1725-35. Review. 2006
50CREBBP, DUP16P133
Oligonucleotide microarray analysis of genomic imbalance in children with mental retardation.
Friedman JM, Baross A, Delaney AD, Ally A, Arbour L, Armstrong L, Asano J, Bailey DK, Barber S, Birch P, Brown-John M, Cao M, Chan S, Charest DL, Farnoud N, Fernandes N, Flibotte S, Go A, Gibson WT, Holt RA, Jones SJ, Kennedy GC, Krzywinski M, Langlois S, Li HI, McGillivray BC, Nayar T, Pugh TJ, Rajcan-Separovic E, Schein JE, Schnerch A, Siddiqui A, Van Allen MI, Wilson G, Yong SL, Zahir F, Eydoux P, Marra MA.
Am J Hum Genet 79(3):500-13. Epub 2006 Jul 25. Erratum in: Am J Hum Genet. 2006 Dec;79(6):1135. Armstrong, Linlea [added]. 2006
51CREBBP, RSTS, EP300, RSTS2
Genetic Heterogeneity in Rubinstein-Taybi Syndrome: Mutations in Both the CBP and EP300 Genes Cause Disease.
Roelfsema JH, White SJ, Ariyurek Y, Bartholdi D, Niedrist D, Papadia F, Bacino CA, den Dunnen JT, van Ommen GJ, Breuning MH, Hennekam RC, Peters DJ.
Am J Hum Genet 76(4):572-80. Epub 2005 Feb 10. 2005
52BTRC, CREBBP, CSRP2, FKBP8, GAS1, GSK3B, HHAT, HHIP, IFT88, KIF27, KIF3A, KIF7, RAB23, SHH, STIL, STK36, SUFU, VTN
Hedgehog signaling and congenital malformations.
Nieuwenhuis E, Hui CC.
Clin Genet 67(3):193-208. 2005
53CREBBP, RSTS
DNA sequencing of CREBBP demonstrates mutations in 56% of patients with Rubinstein-Taybi syndrome (RSTS) and in another patient with incomplete RSTS.
Bartsch O, Schmidt S, Richter M, Morlot S, Seemanova E, Wiebe G, Rasi S.
Hum Genet 117(5):485-93. Epub 2005 Jul 14. 2005
54TRIP10, CREBBP, GAK, CNOT3, EIF2B1, SH3GL1, AP1B1
Identification of novel CBP interacting proteins in embryonic orofacial tissue.
Yin X, Warner DR, Roberts EA, Pisano MM, Greene RM.
Biochem Biophys Res Commun 329(3):1010-7. 2005
55CREBBP, LAMA3
CREB-binding protein regulates apoptosis and growth of HMECs grown in reconstituted ECM via laminin-5.
Dietze EC, Bowie ML, Mrozek K, Caldwell LE, Neal C, Marjoram RJ, Troch MM, Bean GR, Yokoyama KK, Ibarra CA, Seewaldt VL.
J Cell Sci 118(Pt 21):5005-22. Epub 2005 Oct 11. 2005
56CREBBP, SET
The histone chaperone SET/TAF-Ibeta interacts functionally with the CREB-binding protein.
Karetsou Z, Martic G, Sflomos G, Papamarcaki T.
Biochem Biophys Res Commun 335(2):322-7. 2005
57CREBBP, CITED2, HIF1A
Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites.
De Guzman RN, Martinez-Yamout MA, Dyson HJ, Wright PE.
J Biol Chem 279(4):3042-9. Epub 2003 Oct 31. 2004
58CREBBP, NCOA1, ETS2, TP53, IRF3, EP300
A Conserved alpha-helical motif mediates the binding of diverse nuclear proteins to the SRC1 interaction domain of CBP.
Matsuda S, Harries JC, Viskaduraki M, Troke PJ, Kindle KB, Ryan C, Heery DM.
J Biol Chem 279(14):14055-64. Epub 2004 Jan 13. 2004
59CREBBP, IVL, KAT2B
Regulation of the human involucrin gene promoter by co-activator proteins.
Tran NQ, Crowe DL.
Biochem J 381(Pt 1):267-73. 2004
60TCF3, CREBBP, HMCN1
E2A-PBX1 interacts directly with the KIX domain of CBP/p300 in the induction of proliferation in primary hematopoietic cells.
Bayly R, Chuen L, Currie RA, Hyndman BD, Casselman R, Blobel GA, LeBrun DP.
J Biol Chem 279(53):55362-71. Epub 2004 Oct 26. 2004
61NLRP1, CREBBp
NALP1 is a transcriptional target for cAMP-response-element-binding protein (CREB) in myeloid leukaemia cells.
Sanz C, Calasanz MJ, Andreu E, Richard C, Prosper F, Fernandez-Luna JL.
Biochem J 384(Pt 2):281-6. 2004
62CREBBP, RSTS
Loss of CBP acetyltransferase activity by PHD finger mutations in Rubinstein-Taybi syndrome
Kalkhoven E, Roelfsema JH, Teunissen H, den Boer A, Ariyurek Y, Zantema A, Breuning MH, Hennekam RC, Peters DJ.
Hum Mol Genet 12(4):441-50. 2003
63CREBBP, KAT6B
t(10;16)(q22;p13) and MORF-CREBBP fusion is a recurrent event in acute myeloid leukemia.
Vizmanos JL, Larrayoz MJ, Lahortiga I, Floristan F, Alvarez C, Odero MD, Novo FJ, Calasanz MJ.
Genes Chromosomes Cancer 36(4):402-5. 2003
64CREBBP, EP300
Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.
Tillinghast GW, Partee J, Albert P, Kelley JM, Burtow KH, Kelly K.
Genes Chromosomes Cancer 37(2):121-31. 2003
65ATRX, CREBBP, DNMT3B, MECP2, RPS6KA3
Syndromes of disordered chromatin remodeling.
Ausio J, Levin DB, De Amorim GV, Bakker S, Macleod PM.
Clin Genet 64(2):83-95. 2003
66CREBBP, EP300, SOX9
Transcriptional co-activators CREB-binding protein and p300 regulate chondrocyte-specific gene expression via association with Sox9.
Tsuda M, Takahashi S, Takahashi Y, Asahara H.
J Biol Chem 278(29):27224-9. Epub 2003 May 5. 2003
67CREBBP,SERTAD1
Regulation of CREB-mediated transcription by association of CDK4 binding protein p34SEI-1 with CBP.
Hirose T, Fujii R, Nakamura H, Aratani S, Fujita H, Nakazawa M, Nakamura K, Nishioka K, Nakajima T.
Int J Mol Med 11(6):705-12. 2003
68CREBBP, HDAC1, NFKB1, NFKB2
The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1.
Zhong H, May MJ, Jimi E, Ghosh S.
Mol Cell 9(3):625-36. 2002
69CREBBP, HLA-G
HLA-G transactivation by cAMP-response element-binding protein (CREB). An alternative transactivation pathway to the conserved major histocompatibility complex (MHC) class I regulatory routes.
Gobin SJ, Biesta P, de Steenwinkel JE, Datema G, van den Elsen PJ.
J Biol Chem 277(42):39525-31. Epub 2002 Aug 14. 2002
70CREBBP, KAT6B
Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13).
Panagopoulos I, Fioretos T, Isaksson M, Samuelsson U, Billstrom R, Strombeck B, Mitelman F, Johansson B.
Hum Mol Genet 10(4):395-404. 2001
71CREBBP
Defect of histone acetyltransferase activity of the nuclear transcriptional coactivator CBP in Rubinstein-Taybi syndrome.
Murata T, Kurokawa R, Krones A, Tatsumi K, Ishii M, Taki T, Masuno M, Ohashi H, Yanagisawa M, Rosenfeld MG, Glass CK, Hayashi Y.
Hum Mol Genet 10(10):1071-6. 2001
72ATRX, CREBBP, DNMT3B, MECP2
Human diseases with underlying defects in chromatin structure and modification.
Hendrich B, Bickmore W.
Hum Mol Genet 10(20):2233-42. 2001
73CREBBP, RSTS
Variation in microdeletions of the cyclic AMP-responsive element-binding protein gene at chromosome band 16p13.3 in the rubinstein-taybi syndrome.
Blough RI, Petrij F, Dauwerse JG, Milatovich-Cherry A, Weiss L, Saal HM, Rubinstein JH.
Am J Med Genet 90(1):29-34 2000
74BRCA1, CREBBP, EP300
CBP/p300 interact with and function as transcriptional coactivators of BRCA1.
Pao GM, Janknecht R, Ruffner H, Hunter T, Verma IM.
Proc Natl Acad Sci U S A 97(3):1020-5. 2000
75CREBBP, TNF
A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor alpha gene expression.
Falvo JV, Brinkman BM, Tsytsykova AV, Tsai EY, Yao TP, Kung AL, Goldfeld AE.
Proc Natl Acad Sci U S A 97(8):3925-9. 2000
76CREBBP, HD, HTT, TP53
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
Steffan JS, Kazantsev A, Spasic-Boskovic O, Greenwald M, Zhu YZ, Gohler H, Wanker EE, Bates GP, Housman DE, Thompson LM.
Proc Natl Acad Sci U S A 97(12):6763-8. 2000
77CREBBP, PML
Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling.
Doucas V, et al.
Proc Natl Acad Sci U S A 96(6):2627-2632. 1999
78AMLT3, CREBBP, KAT6A
A case of inv(8)(p11q24) associated with acute myeloid leukemia involves the MOZ and CBP genes in a masked t(8;16).
Chaffanet M, et al.
Genes Chromosomes Cancer 26(2):161-165 1999
79CREBBP, RSTS
FISH studies in 45 patients with Rubinstein-Taybi syndrome: deletions associated with polysplenia, hypoplastic left heart and death in infancy.
Bartsch O, et al.
Eur J Hum Genet 7(7):748-56 1999
80CREBBP, RSTS
Submicroscopic deletion of chromosome 16p13.3 in patients with Rubinstein-Taybi syndrome.
Taine L, et al.
Am J Med Genet 78 : 267-270. 1998
81CREBBP, SMAD2, SMAD4
CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor beta transcriptional responses in endothelial cells.
Topper JN, et al.
Proc Natl Acad Sci U S A 95 : 9506-9511. 1998
82CREBBP, EGR1
cAMP-response-element-binding-protein-binding protein (CBP) and p300 are transcriptional co-activators of early growth response factor-1 (Egr-1).
Silverman ES, et al.
Biochem J 336 : 183-189. 1998
83CREBBP, PML
Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body.
LaMorte VJ, et al.
Proc Natl Acad Sci U S A 95(9):4991-6. 1998
84CREBBP, HIF1A
Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha.
Kallio PJ, Okamoto K, O'Brien S, Carrero P, Makino Y, Tanaka H, Poellinger L.
EMBO J 17(22):6573-86 1998
85CREBBP
Construction of 1.2-Mb contig surrounding, and molecular analysis of the human CREB-binding protein (CBP/CREBBP) gene on chromosome 16p13.3.
Giles RH, Petrij F, Dauwerse HG, den Hollander AI, Lushnikova T, van Ommen GJ, Goodman RH, Deaven LL, Doggett NA, Peters DJ, Breuning MH.
Genomics 42(1):96-114. 1997
86CREBBP, KMT2A
The t(11;16)(q23;p13) translocation in myelodysplastic syndrome fuses the MLL gene to the CBP gene.
Taki T, Sako M, Tsuchida M, Hayashi Y.
Blood 89(11):3945-50. 1997
87CREBBP
MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3).
Sobulo OM, Borrow J, Tomek R, Reshmi S, Harden A, Schlegelberger B, Housman D, Doggett NA, Rowley JD, Zeleznik-Le NJ.
Proc Natl Acad Sci U S A 94(16):8732-7. 1997
88CREBBP, KMT2A
Novel MLL-CBP fusion transcript in therapy-related chronic myelomonocytic leukemia with a t(11;16)(q23;p13) chromosome translocation.
Satake N, Ishida Y, Otoh Y, Hinohara S, Kobayashi H, Sakashita A, Maseki N, Kaneko Y.
Genes Chromosomes Cancer 20(1):60-3. 1997
89AMLT3, CREBBP, KAT6A
Abnormalities of chromosome band 8p11 in leukemia : two clinical syndromes can be distinguished on the basis of MOZ involvement.
Aguiar RC, Chase A, Coulthard S, Macdonald DH, Carapeti M, Reiter A, Sohal J, Lennard A, Goldman JM, Cross NC.
Blood 90(8):3130-5. 1997
90CREBBP, STAT2
Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha.
Bhattacharya S, Eckner R, Grossman S, Oldread E, Arany Z, D'Andrea A, Livingston DM.
Nature 383(6598):344-7 1996
91CREBBP, HIF1A
An essential role for p300/CBP in the cellular response to hypoxia.
Arany Z, Huang LE, Eckner R, Bhattacharya S, Jiang C, Goldberg MA, Bunn HF, Livingston DM.
Proc Natl Acad Sci U S A 93(23):12969-73 1996
92AMLT3, CREBBP, KAT6A
The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein.
Borrow J, Stanton VP Jr, Andresen JM, Becher R, Behm FG, Chaganti RS,Civin CI, Disteche C, Dube I, Frischauf AM, Horsman D, Mitelman F, Volinia S,Watmore AE, Housman DE.
Nat Genet 14(1):33-41. 1996
93CREBBP
Localization of human CREB-binding protein gene (CREBBP) to 16p13.2-p13.3 by fluorescence in situ hybridization.
Wydner KL, et al.
Genomics 30 : 395-396. 1995
94CREBBP
Localization of human CREBBP (CREB Binding Protein) to 16p13.3 by fluorescence in situ hybridization.
Chen XN, et al.
Cytogenet Cell Genet 71 : 56-57. 1995
95EP300, CREBBP
Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP.
Lundblad JR, et al.
Nature 374 : 85-88. 1995
96RSTS, CREBBP
Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP.
Petrij F, et al.
Nature 376 : 348-351. 1995
97CREBBP
Phosphorylated CREB binds specifically to the nuclear protien CBP.
Chrivia JC, et al.
Nature 365 : 855-859. 1993