Citations for
Cellular Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Mediates Nuclear Import of Human Bocavirus 1 NP1 Protein and Modulates Viral Capsid Protein Expression.
Wang X, Xu P, Cheng F, Li Y, Wang Z, Hao S, Wang J, Ning K, Ganaie SS, Engelhardt JF, Yan Z, Qiu J.
J Virol 94(2). pii: e01444-19. doi: 10.1128/JVI.01444-19. Print 2020 Jan 6. 2020
Differential role for phosphorylation in alternative polyadenylation function versus nuclear import of SR-like protein CPSF6.
Jang S, Cook NJ, Pye VE, Bedwell GJ, Dudek AM, Singh PK, Cherepanov P, Engelman AN.
Nucleic Acids Res 47(9):4663-4683. doi: 10.1093/nar/gkz206. 2019
A case of acute myeloid leukemia with promyelocytic features characterized by expression of a novel RARG-CPSF6 fusion.
Miller CA, Tricarico C, Skidmore ZL, Uy GL, Lee YS, Hassan A, O'Laughlin MD, Schmidt H, Tian L, Duncavage EJ, Griffith M, Griffith OL, Welch JS, Wartman LD.
Blood Adv 2(11):1295-1299. doi: 10.1182/bloodadvances.2017014183. No abstract available. 2018
Molecular Mechanisms for CFIm-Mediated Regulation of mRNA Alternative Polyadenylation.
Zhu Y, Wang X, Forouzmand E, Jeong J, Qiao F, Sowd GA, Engelman AN, Xie X, Hertel KJ, Shi Y.
Mol Cell 69(1):62-74.e4. doi: 10.1016/j.molcel.2017.11.031. Epub 2017 Dec 21. 2018
CPSF6 is a Clinically Relevant Breast Cancer Vulnerability Target: Role of CPSF6 in Breast Cancer.
Binothman N, Hachim IY, Lebrun JJ, Ali S.
EBioMedicine 21:65-78. doi: 10.1016/j.ebiom.2017.06.023. Epub 2017 Jun 24. 2017
The ability of TNPO3-depleted cells to inhibit HIV-1 infection requires CPSF6.
Fricke T, Valle-Casuso JC, White TE, Brandariz-Nuñez A, Bosche WJ, Reszka N, Gorelick R, Diaz-Griffero F.
Retrovirology 10:46. doi: 10.1186/1742-4690-10-46. 2013
CPSF6 defines a conserved capsid interface that modulates HIV-1 replication.
Price AJ, Fletcher AJ, Schaller T, Elliott T, Lee K, KewalRamani VN, Chin JW, Towers GJ, James LC.
PLoS Pathog 8(8):e1002896. doi: 10.1371/journal.ppat.1002896. Epub 2012 Aug 30. 2012
Evidence that cleavage factor Im is a heterotetrameric protein complex controlling alternative polyadenylation.
Kim S, Yamamoto J, Chen Y, Aida M, Wada T, Handa H, Yamaguchi Y.
Genes Cells 15(9):1003-13. doi: 10.1111/j.1365-2443.2010.01436.x. Epub 2010 Jul 29. 2010
Mammalian pre-mRNA 3' end processing factor CF I m 68 functions in mRNA export.
Ruepp MD, Aringhieri C, Vivarelli S, Cardinale S, Paro S, Schümperli D, Barabino SM.
Mol Biol Cell 20(24):5211-23. doi: 10.1091/mbc.E09-05-0389. 2009
The t(1;9)(p34;q34) and t(8;12)(p11;q15) fuse pre-mRNA processing proteins SFPQ (PSF) and CPSF6 to ABL and FGFR1.
Hidalgo-Curtis C, Chase A, Drachenberg M, Roberts MW, Finkelstein JZ, Mould S, Oscier D, Cross NC, Grand FH.
Genes Chromosomes Cancer 47(5):379-85.PMID: 18205209 2008
Pre-messenger RNA cleavage factor I (CFIm): potential role in alternative polyadenylation during spermatogenesis.
Sartini BL, Wang H, Wang W, Millette CF, Kilpatrick DL.
Biol Reprod 78(3):472-82. Epub 2007 Nov 21. 2008
Subnuclear localization and dynamics of the Pre-mRNA 3' end processing factor mammalian cleavage factor I 68-kDa subunit.
Cardinale S, Cisterna B, Bonetti P, Aringhieri C, Biggiogera M, Barabino SM.
Mol Biol Cell 18(4):1282-92. Epub 2007 Jan 31. 2007
13CPSF6, U2AF2
An interaction between U2AF 65 and CF I(m) links the splicing and 3' end processing machineries.
Millevoi S, Loulergue C, Dettwiler S, Karaa SZ, Keller W, Antoniou M, Vagner S.
EMBO J 25(20):4854-64. Epub 2006 Oct 5. 2006
Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization.
Dettwiler S, Aringhieri C, Cardinale S, Keller W, Barabino SM.
J Biol Chem 279(34):35788-97. Epub 2004 May 28. 2004
A mechanism for the regulation of pre-mRNA 3' processing by human cleavage factor Im.
Brown KM, Gilmartin GM.
Mol Cell 12(6):1467-76. 2003
Human pre-mRNA cleavage factor Im is related to spliceosomal SR proteins and can be reconstituted in vitro from recombinant subunits.
Ruegsegger U, Blank D, Keller W.
Mol Cell 1(2):243-53. 1998
Purification and characterization of human cleavage factor Im involved in the 3' end processing of messenger RNA precursors.
Rüegsegger U, Beyer K, Keller W.
J Biol Chem 271(11):6107-13. 1996