1 | CPLX1, CPLX2
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| Presynaptic proteins complexin-I and complexin-II differentially influence cognitive function in early and late stages of Alzheimer's disease.
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| Ramos-Miguel A, Sawada K, Jones AA, Thornton AE, Barr AM, Leurgans SE, Schneider JA, Bennett DA, Honer WG.
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| Acta Neuropathol 133(3):395-407. doi: 10.1007/s00401-016-1647-9. Epub 2016 Nov 19.
2017
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2 | CPLX1, CPLX2
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| Complexin facilitates exocytosis and synchronizes vesicle release in two secretory model systems.
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| Lin MY, Rohan JG, Cai H, Reim K, Ko CP, Chow RH.
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| J Physiol 591(10):2463-73. doi: 10.1113/jphysiol.2012.244517. Epub 2013 Feb 11.
2013
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3 | CPLX2
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| Identification of complexin II in astrocytes: a possible regulator of glutamate release in these cells.
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| Hazell AS, Wang D.
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| Biochem Biophys Res Commun 404(1):228-32. Epub 2010 Nov 24.
2011
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4 | CPLX2
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| Modification of cognitive performance in schizophrenia by complexin 2 gene polymorphisms.
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| Begemann M, Grube S, Papiol S, Malzahn D, Krampe H, Ribbe K, Friedrichs H, Radyushkin KA, El-Kordi A, Benseler F, Hannke K, Sperling S, Schwerdtfeger D, Thanhäuser I, Gerchen MF, Ghorbani M, Gutwinski S, Hilmes C, Leppert R, Ronnenberg A, Sowislo J, Stawicki S, Stödtke M, Szuszies C, Reim K, Riggert J, Eckstein F, Falkai P, Bickeböller H, Nave KA, Brose N, Ehrenreich H.
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| Arch Gen Psychiatry 67(9):879-88. Erratum in: Arch Gen Psychiatry. 2010 Oct;67(10):1077.
2010
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5 | CPLX2, STX3, STX4, VAMP2
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| Complexin 2 modulates vesicle-associated membrane protein (VAMP) 2-regulated zymogen granule exocytosis in pancreatic acini.
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| Falkowski MA, Thomas DD, Groblewski GE.
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| J Biol Chem 285(46):35558-66. Epub 2010 Sep 9.
2010
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6 | CPLX2
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| Complexin2 null mutation requires a 'second hit' for induction of phenotypic changes relevant to schizophrenia.
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| Radyushkin K, El-Kordi A, Boretius S, Castaneda S, Ronnenberg A, Reim K, Bickeböller H, Frahm J, Brose N, Ehrenreich H.
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| Genes Brain Behav 9(6):592-602. Epub 2010 Apr 19.
2010
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7 | CPLX2, STX3
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| Complexin II regulates degranulation in RBL-2H3 cells by interacting with SNARE complex containing syntaxin-3.
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| Tadokoro S, Nakanishi M, Hirashima N.
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| Cell Immunol 261(1):51-6. Epub 2009 Oct 25. 2010
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8 | CPLX1, CPLX2, SYT1
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| Binding of the complexin N terminus to the SNARE complex potentiates synaptic-vesicle fusogenicity.
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| Xue M, Craig TK, Xu J, Chao HT, Rizo J, Rosenmund C.
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| Nat Struct Mol Biol 17(5):568-75. doi: 10.1038/nsmb.1791. Epub 2010 Apr 18.
2010
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9 | CPLX1, CPLX2
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| Regulation of complexin 1 and complexin 2 in the developing human prefrontal cortex.
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| Salimi K, Glantz LA, Hamer RM, German TT, Gilmore JH, Jarskog LF.
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| Synapse 62(4):273-82.
2008
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10 | CPLX2
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| Complexin II plays a positive role in Ca2+-triggered exocytosis by facilitating vesicle priming.
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| Cai H, Reim K, Varoqueaux F, Tapechum S, Hill K, Sørensen JB, Brose N, Chow RH.
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| Proc Natl Acad Sci U S A 105(49):19538-43. Epub 2008 Nov 25.
2008
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11 | CPLX1, CPLX2
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| No association of complexin1 and complexin2 genes with schizophrenia in a Japanese population.
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| Kishi T, Ikeda M, Suzuki T, Kitajima T, Yamanouchi Y, Kinoshita Y, Ozaki N, Iwata N.
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| Schizophr Res 82(2-3):185-9. Epub 2006 Jan 25.
2006
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12 | CPLX2
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| Structural organization of the human complexin 2 gene (CPLX2) and aspects of its functional activity.
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| Raevskaya NM, Dergunova LV, Vladychenskaya IP, Stavchansky VV, Oborina MV, Poltaraus AB, Limborska SA.
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| Gene 359:127-37. 2005
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13 | CPLX1, CPLX2
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| SNARE complex oligomerization by synaphin/complexin is essential for synaptic vesicle exocytosis.
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| Tokumaru H, Umayahara K, Pellegrini LL, Ishizuka T, Saisu H, Betz H, Augustine GJ, Abe T.
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| Cell 104(3):421-32. 2001
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14 | CPLX1, CPLX2
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| Complexins regulate a late step in Ca2+-dependent neurotransmitter release.
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| Reim K, Mansour M, Varoqueaux F, McMahon HT, Sudhof TC, Brose N, Rosenmund C.
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| Cell 104(1):71-81. 2001
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15 | CPLX1, CPLX2
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| Complexins: cytosolic proteins that regulate SNAP receptor function.
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| McMahon HT, Missler M, Li C, Sudhof TC.
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| Cell 83(1):111-9. 1995
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