| 1 | COQ7
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| The anti-neurodegeneration drug clioquinol inhibits the aging-associated protein CLK-1.
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| Wang Y, Branicky R, Stepanyan Z, Carroll M, Guimond MP, Hihi A, Hayes S, McBride K, Hekimi S.
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| J Biol Chem Biol Chem. 2008 Oct 15. [Epub ahead of print]
2008
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| 2 | COQ7
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| Clk-1 deficiency induces apoptosis associated with mitochondrial dysfunction in mouse embryos.
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| Takahashi M, Shimizu T, Moriizumi E, Shirasawa T.
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| Mech Ageing Dev 129(5):291-8. Epub 2008 Feb 12.
2008
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| 3 | ATM, COQ7, GZMB, GZMH
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| Aberrant recombination involving the granzyme locus occurs in Atm-/- T-cell lymphomas.
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| Winrow CJ, Pankratz DG, Vibat CR, Bowen TJ, Callahan MA, Warren AJ, Hilbush BS, Wynshaw-Boris A, Hasel KW, Weaver Z, Lockhart DJ, Barlow C.
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| Hum Mol Genet 14(18):2671-84. Epub 2005 Aug 8. 2005
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| 4 | COQ7
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| coq7/clk-1 regulates mitochondrial respiration and the generation of reactive oxygen species via coenzyme Q.
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| Nakai D, Shimizu T, Nojiri H, Uchiyama S, Koike H, Takahashi M, Hirokawa K, Shirasawa T.
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| Aging Cell 3(5):273-81.
2004
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| 5 | COQ7
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| A new member of the family of di-iron carboxylate proteins. Coq7 (clk-1), a membrane-bound hydroxylase involved in ubiquinone biosynthesis.
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| Stenmark P, Grünler J, Mattsson J, Sindelar PJ, Nordlund P, Berthold DA.
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| J Biol Chem 276(36):33297-300. Epub 2001 Jul 2.
2001
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| 6 | COQ7
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| Orthologues of the Caenorhabditis elegans longevity gene clk-1 in mouse and human.
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| Asaumi S, et al.
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| Genomics 58(3):293-301. 1999
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| 7 | COQ7
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| Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis.
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| Jonassen T, Proft M, Randez-Gil F, Schultz JR, Marbois BN, Entian KD, Clarke CF.
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| J Biol Chem 273(6):3351-7. 1998
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| 8 | COQ7
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| Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.
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| Ewbank JJ, et al.
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| Science 275(5302):980-3 1997
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