| 1 | COMT
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| Endothelial dysfunction in gestational hypertension induced by catechol-O-methyltransferase inhibition.
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| Hernandez M, Hernandez I, Rodriguez F, Pertegal M, Bonacasa B, Salom MG, Quesada T, Fenoy FJ.
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| Exp Physiol 98(3):856-66. doi: 10.1113/expphysiol.2012.067389. Epub 2012 Oct 26.
2013
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| 2 | BDNF, COMT
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| Interaction of BDNF and COMT polymorphisms on paired-associative stimulation-induced cortical plasticity.
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| Witte AV, Kürten J, Jansen S, Schirmacher A, Brand E, Sommer J, Flöel A.
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| J Neurosci 32(13):4553-61. doi: 10.1523/JNEUROSCI.6010-11.2012.
2012
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| 3 | COMT
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| Serotonin-induced hypersensitivity via inhibition of catechol O-methyltransferase activity.
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| Tsao D, Wieskopf JS, Rashid N, Sorge RE, Redler RL, Segall SK, Mogil JS, Maixner W, Dokholyan NV, Diatchenko L.
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| Mol Pain 8:25. doi: 10.1186/1744-8069-8-25.
2012
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| 4 | COMT
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| Association of COMT Val158Met polymorphism and breast cancer risk: an updated meta-analysis.
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| Qin X, Peng Q, Qin A, Chen Z, Lin L, Deng Y, Xie L, Xu J, Li H, Li T, Li S, Zhao J.
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| Diagn Pathol 7:136. doi: 10.1186/1746-1596-7-136.
2012
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| 5 | APOE, COMT
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| Role of the apolipoprotein E and catechol-O-methyltransferase genes in prospective and retrospective memory traits.
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| Dongés B, Haupt LM, Lea RA, Chan RC, Shum DH, Griffiths LR.
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| Gene 506(1):135-40. doi: 10.1016/j.gene.2012.06.067. Epub 2012 Jul 3.
2012
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| 6 | COMT
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| COMT as a drug target for cognitive functions and dysfunctions.
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| Scheggia D, Sannino S, Scattoni ML, Papaleo F.
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| CNS Neurol Disord Drug Targets 11(3):209-21. Review.
2012
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| 7 | COMT
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| COMT val158met polymorphism and neural pain processing.
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| Schmahl C, Ludäscher P, Greffrath W, Kraus A, Valerius G, Schulze TG, Treutlein J, Rietschel M, Smolka MN, Bohus M.
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| PLoS One 7(1):e23658. doi: 10.1371/journal.pone.0023658. Epub 2012 Jan 11.
2012
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| 8 | COMT
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| Orientation and cellular distribution of membrane-bound catechol-O-methyltransferase in cortical neurons: implications for drug development.
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| Chen J, Song J, Yuan P, Tian Q, Ji Y, Ren-Patterson R, Liu G, Sei Y, Weinberger DR.
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| J Biol Chem 286(40):34752-60. doi: 10.1074/jbc.M111.262790. Epub 2011 Aug 16.
2011
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| 9 | COMT
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| Distribution of catechol-O-methyltransferase (COMT) proteins and enzymatic activities in wild-type and soluble COMT deficient mice.
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| Myöhänen TT, Schendzielorz N, Männistö PT.
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| J Neurochem 113(6):1632-43. doi: 10.1111/j.1471-4159.2010.06723.x. Epub 2010 Mar 31.
2010
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| 10 | COMT, SLC6A3
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| Variation in dopamine genes influences responsivity of the human reward system.
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| Dreher JC, Kohn P, Kolachana B, Weinberger DR, Berman KF.
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| Proc Natl Acad Sci U S A 106(2):617-22. Epub 2008 Dec 22.
2009
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| 11 | COMT, TPMT
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| Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.
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| Ross CJ, Katzov-Eckert H, Dubé MP, Brooks B, Rassekh SR, Barhdadi A, Feroz-Zada Y, Visscher H, Brown AM, Rieder MJ, Rogers PC, Phillips MS, Carleton BC, Hayden MR; CPNDS Consortium.
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| Nat Genet 41(12):1345-9. Epub 2009 Nov 8.PMID: 19898482 2009
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| 12 | DEL22q11, COMT, SCZD4
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| Schizophrenia and 22q11.2 deletion syndrome.
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| Bassett AS, Chow EW.
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| Curr Psychiatry Rep 10(2):148-57. 2008
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| 13 | PRODH, COMT
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| PRODH gene is associated with executive function in schizophrenic families.
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| Li T, Ma X, Hu X, Wang Y, Yan C, Meng H, Liu X, Toulopoulou T, Murray RM, Collier DA.
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| Am J Med Genet B Neuropsychiatr Genet 147B(5):654-7. 2008
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| 14 | CHGB, COMT, CSF2RA, DAO, DAOA, DRD3, DTNBP1, HTR2A, PIP4K2A, RGS4, SCZD3
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| Candidate genes for schizophrenia: a survey of association studies and gene ranking.
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| Sun J, Kuo PH, Riley BP, Kendler KS, Zhao Z.
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| Am J Med Genet B Neuropsychiatr Genet 147B(7):1173-81. 2008
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| 15 | APOE, COMT, DAO, DRD1, DRD2, DRD4, DTNBP1, GABRB2, GRIN2B, HP, IL1B, MTHFR, PLXNA2, SCZD23, SLC6A4, TP53, TPH1
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| Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database.
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| Allen NC, Bagade S, McQueen MB, Ioannidis JP, Kavvoura FK, Khoury MJ, Tanzi RE, Bertram L.
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| Nat Genet 40(7):827-34. 2008
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| 16 | ARVCF, COMT, GNB1L, PRODH
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| Candidate genes and the behavioral phenotype in 22q11.2 deletion syndrome.
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| Prasad SE, Howley S, Murphy KC.
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| Dev Disabil Res Rev 14(1):26-34. Review. 2008
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| 17 | COMT
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| Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia.
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| Kanasaki K, Palmsten K, Sugimoto H, Ahmad S, Hamano Y, Xie L, Parry S, Augustin HG, Gattone VH, Folkman J, Strauss JF, Kalluri R.
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| Nature 453(7198):1117-21. doi: 10.1038/nature06951. Epub 2008 May 11.
2008
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| 18 | DEL22Q11, PRODH, HPI, VCF, COMT
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| Involvement of hyperprolinemia in cognitive and psychiatric features of the 22q11 deletion syndrome.
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| Raux G, Bumsel E, Hecketsweiler B, van Amelsvoort T, Zinkstok J, Manouvrier-Hanu S, Fantini C, Breviere GM, Di Rosa G, Pustorino G, Vogels A, Swillen A, Legallic S, Bou J, Opolczynski G, Drouin-Garraud V, Lemarchand M, Philip N, Gerard-Desplanches A, Carlier M, Philippe A, Nolen MC, Heron D, Sarda P, Lacombe D, Coizet C, Alembik Y, Layet V, Afenjar A, Hannequin D, Demily C, Petit M, Thibaut F, Frebourg T, Campion D.
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| Hum Mol Genet 16(1):83-91. Epub 2006 Nov 29. 2007
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| 19 | COMT
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| Genetic variation in catechol-O-methyltransferase (COMT) and obesity in the prostate, lung, colorectal, and ovarian (PLCO) cancer screening trial.
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| Wang SS, Morton LM, Bergen AW, Lan EZ, Chatterjee N, Kvale P, Hayes RB, Chanock SJ, Caporaso NE.
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| Hum Genet 122(1):41-9. Epub 2007 May 12. 2007
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| 20 | ADHD, COMT, DRD4, SLC6A3
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| An exploratory study of the relationship between four candidate genes and neurocognitive performance in adult ADHD.
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| Boonstra AM, Kooij JJ, Buitelaar JK, Oosterlaan J, Sergeant JA, Heister JG, Franke B.
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| Am J Med Genet B Neuropsychiatr Genet [Epub ahead of print] 2007
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| 21 | COMT, GRIN2A
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| Molecular mechanisms of schizophrenia.
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| Lang UE, Puls I, Muller DJ, Strutz-Seebohm N, Gallinat J.
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| Cell Physiol Biochem 20(6):687-702. Review. 2007
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| 22 | COMT, DEL22Q11, SCZD4
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| Risk factors for the emergence of psychotic disorders in adolescents with 22q11.2 deletion syndrome.
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| Gothelf D, Feinstein C, Thompson T, Gu E, Penniman L, Van Stone E, Kwon H, Eliez S, Reiss AL.
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| Am J Psychiatry 164(4):663-9. 2007
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| 23 | DAOA, PRODH, DTNBP1, NRG1, DISC1, NOS1Ap, ZDHHC8, CLINT1, TAAR6, COMT, GABRA1, GABRP, HPI
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| Schizophrenia genetics: uncovering positional candidate genes.
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| Karayiorgou M, Gogos JA.
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| Eur J Hum Genet 14(5):512-9. 2006
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| 24 | DTNBP1, NRG1, TAAR6, DTNBP1, COMT, RGS4, PPP3CC, ZDHHC8, AKT1, DAOA, G30
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| Molecular genetic studies of schizophrenia.
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| Riley B, Kendler KS.
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| Eur J Hum Genet 14(6):669-80. 2006
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| 25 | COMT
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| Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder.
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| Abdolmaleky HM, Cheng KH, Faraone SV, Wilcox M, Glatt SJ, Gao F, Smith CL, Shafa R, Aeali B, Carnevale J, Pan H, Papageorgis P, Ponte JF, Sivaraman V, Tsuang MT, Thiagalingam S.
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| Hum Mol Genet 15(21):3132-45. Epub 2006 Sep 19.
2006
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| 26 | COMT, DAOA, DISC1
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| Neurobiology of schizophrenia.
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| Ross CA, Margolis RL, Reading SA, Pletnikov M, Coyle JT.
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| Neuron 52(1):139-53. Review. 2006
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| 27 | COMT, DAO, DAOA, DISC1, DTNBP1, HPI, MAFD13, MAFD17, NRG1, P2RX7, PPP3CC, PRODH, RGS4, SCZD23, TAAR6, ZDHHC8
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| The genetics of schizophrenia and bipolar disorder: dissecting psychosis.
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| Craddock N, O'donovan MC, Owen MJ.
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| J Med Genet 42(3):193-204. 2005
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| 28 | FAM58B, VCF, HPI, COMT, PRODH
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| KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers.
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| Corson TW, Huang A, Tsao MS, Gallie BL.
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| Oncogene 24(30):4741-53. 2005
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| 29 | COMT, HT2A, DRD2, DRD4, SLC6A3
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| Genetics and epigenetics in major psychiatric disorders: dilemmas, achievements, applications, and future scope.
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| Abdolmaleky HM, Thiagalingam S, Wilcox M.
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| Am J Pharmacogenomics 5(3):149-60. Review. 2005
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| 30 | COMT, DEL22Q11
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| COMT: a common susceptibility gene in bipolar disorder and schizophrenia.
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| Shifman S, Bronstein M, Sternfeld M, Pisante A, Weizman A, Reznik I, Spivak B, Grisaru N, Karp L, Schiffer R, Kotler M, Strous RD, Swartz-Vanetik M, Knobler HY, Shinar E, Yakir B, Zak NB, Darvasi A.
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| Am J Med Genet 128B(1):61-4. 2004
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| 31 | COMT, DEL22Q11
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| Effects of a functional COMT polymorphism on prefrontal cognitive function in patients with 22q11.2 deletion syndrome.
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| Bearden CE, Jawad AF, Lynch DR, Sokol S, Kanes SJ, McDonald-McGinn DM, Saitta SC, Harris SE, Moss E, Wang PP, Zackai E, Emanuel BS, Simon TJ.
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| Am J Psychiatry 161(9):1700-2. 2004
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| 32 | COMT
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| COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor
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| Zubieta JK, Heitzeg MM, Smith YR, Bueller JA, Xu K, Xu Y, Koeppe RA, Stohler CS, Goldman D.
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| Science 299(5610):1240-3. 2003
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| 33 | COMT, DGCR6, HIRA, SEPTIN5, TSSK1A, TSSK2, ZNF74
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| A comprehensive analysis of 22q11 gene expression in the developing and adult brain.
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| Maynard TM, Haskell GT, Peters AZ, Sikich L, Lieberman JA, LaMantia AS.
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| Proc Natl Acad Sci U S A 100(24):14433-8. Epub 2003 Nov 12. 2003
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| 34 | COMT
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| A highly significant association between a COMT haplotype and schizophrenia.
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| Shifman S, Bronstein M, Sternfeld M, Pisante-Shalom A, Lev-Lehman E, Weizman A, Reznik I, Spivak B, Grisaru N, Karp L, Schiffer R, Kotler M, Strous RD, Swartz-Vanetik M, Knobler HY, Shinar E, Beckmann JS, Yakir B, Risch N, Zak NB, Darvasi A.
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| Am J Hum Genet 71(6):1296-302. 2002
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| 35 | COMT
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| No association between catechol-O-methyltransferase (COMT) gene polymorphism and attention deficit hyperactivity disorder (ADHD) in an Irish sample.
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| Hawi Z, Millar N, Daly G, Fitzgerald M, Gill M.
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| Am J Med Genet 96(3):282-4. 2000
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| 36 | COMT
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| No association between low- and high-activity catecholamine-methyl-transferase (COMT) and attention deficit hyperactivity disorder (ADHD) in a sample of Turkish children.
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| Tahir E, Curran S, Yazgan Y, Ozbay F, Cirakoglu B, Asherson PJ.
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| Am J Med Genet 96(3):285-8. 2000
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| 37 | COMT
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| Haplotype relative risk study of catechol-O-methyltransferase (COMT) and attention deficit hyperactivity disorder (ADHD): Association of the high-enzyme activity val allele with adhd impulsive-hyperactive phenotype.
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| Eisenberg J, et al.
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| Am J Med Genet 88(5):497-502 1999
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| 38 | COMT
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| Linkage disequilibrium on the COMT gene in French schizophrenics and controls.
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| de Chaldee M, et al.
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| Am J Med Genet 88(5):452-457 1999
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| 39 | COMT
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| Homicidal behavior in schizophrenia associated with a genetic polymorphism determining low catechol O-methyltransferase (COMT) activity.
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| Kotler M, Barak P, Cohen H, Averbuch IE, Grinshpoon A, Gritsenko I, Nemanov L, Ebstein RP.
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| Am J Med Genet 88(6):628-33 1999
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| 40 | CACNB1, COMT, PPP2R5B, SATB1, SRP14, XRCC4
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| Identification and chromosomal localization of human genes containing CAG/CTG repeats expressed in testis and brain.
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| Bulle F, Chiannilkulchai N, Pawlak A, Weissenbach J, Gyapay G, Guellaen G.
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| Genome Res 7(7):705-15. 1997
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| 41 | COMT
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| Genomic organization of the human catechol O-methyltransferase gene and its expression from two distinct promoters.
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| Tenhunen J, Salminen M, Lundstrom K, Kiviluoto T, Savolainen R, Ulmanen I.
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| Eur J Biochem 223(3):1049-59. 1994
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| 42 | COMT
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| The human catechol-O-methyltransferase (COMT) gene maps to band q11.2 of chromosome 22 and shows a frequent RFLP with BglI.
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| Winqvist R, et al.
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| Cytogenet Cell Genet 59 : 253-257. 1992
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| 43 | COMT
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| Chromosomal mapping of the human catechol-O-methyltransferase gene to 22q11.1-q11.2.
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| Grossman MH, et al.
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| Genomics 12 : 822-825. 1992
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| 44 | COMT
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| The gene for human catechol-O-methyltransferase (COMT) maps to 22pter-22q11.1.
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| Grossman MH, et al.
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| (HGM11) Cytogenet Cell Genet 58 : 2048. 1991
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| 45 | COMT
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| The increased COMT activity in Down Syndrome patients is not a consequence of dosage effect owing to location of the gene on chromosome 21 : further evidence.
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| Brahe C, et al.
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| Am J Med Genet 24 : 203-204. 1986
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| 46 | COMT
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| Assignment of the catechol-O-methyltransferase gene to human chromosome 22 in somatic cell hybrids.
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| Brahe C, et al.
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| Hum Genet 74 : 230-234. 1986
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| 47 | COMT
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| 370.
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| Orientation and cellular distribution of membrane-bound catechol-O-methyltransferase in cortical neurons: implications for drug development.
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| Chen J, Song J, Yuan P, Tian Q, Ji Y, Ren-Patterson R, Liu G, Sei Y, Weinberger DR hen J, Song J, Yuan P, Tian Q, Ji Y, Ren-Patterson R, Liu G, Sei Y, Weinberger DR.
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| 48 | COMT
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| 430.
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| Severe early-onset preeclampsia is not associated with a change in placental catechol O-methyltransferase (COMT) expression.
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| Palmer K, Saglam B, Whitehead C, Stock O, Lappas M, Tong S almer K, Saglam B, Whitehead C, Stock O, Lappas M, Tong S.
|