Citations for
1COL4A3BP, OSBP, VAPA, VAPB
CARTS biogenesis requires VAP-lipid transfer protein complexes functioning at the endoplasmic reticulum-Golgi interface.
Wakana Y, Kotake R, Oyama N, Murate M, Kobayashi T, Arasaki K, Inoue H, Tagaya M.
Mol Biol Cell 26(25):4686-99. doi: 10.1091/mbc.E15-08-0599. 2015
2COL4A3BP, MRD34
De novo mutations in moderate or severe intellectual disability.
Hamdan FF, Srour M, Capo-Chichi JM, Daoud H, Nassif C, Patry L, Massicotte C, Ambalavanan A, Spiegelman D, Diallo O, Henrion E, Dionne-Laporte A, Fougerat A, Pshezhetsky AV, Venkateswaran S, Rouleau GA, Michaud JL.
PLoS Genet 10(10):e1004772. doi: 10.1371/journal.pgen.1004772. 2014
3COL4A3BP
Phosphoregulation of the ceramide transport protein CERT at serine 315 in the interaction with VAMP-associated protein (VAP) for inter-organelle trafficking of ceramide in mammalian cells.
Kumagai K, Kawano-Kawada M, Hanada K.
J Biol Chem 289(15):10748-60. doi: 10.1074/jbc.M113.528380. 2014
4COL4A3BP
Complement activation by ceramide transporter proteins.
Bode GH, Losen M, Buurman WA, Veerhuis R, Molenaar PC, Steinbusch HW, De Baets MH, Daha MR, Martinez-Martinez P.
J Immunol 192(3):1154-61. doi: 10.4049/jimmunol.1301673. 2014
5COL4A3BP
Crystal structure of the pleckstrin homology domain from the ceramide transfer protein: implications for conformational change upon ligand binding.
Prashek J, Truong T, Yao X.
PLoS One 8(11):e79590. doi: 10.1371/journal.pone.0079590. 2013
6COL4A3BP
Ceramide and its transport protein (CERT) contribute to deterioration of mitochondrial structure and function in aging oocytes.
Kujjo LL, Acton BM, Perkins GA, Ellisman MH, D'Estaing SG, Casper RF, Jurisicova A, Perez GI.
Mech Ageing Dev 134(1-2):43-52. doi: 10.1016/j.mad.2012.12.001. 2013
7COL4A3BP
Structural basis for the Golgi association by the pleckstrin homology domain of the ceramide trafficking protein (CERT).
Sugiki T, Takeuchi K, Yamaji T, Takano T, Tokunaga Y, Kumagai K, Hanada K, Takahashi H, Shimada I.
J Biol Chem 287(40):33706-18. 2012
8APCS, COL4A3BP
Goodpasture antigen-binding protein/ceramide transporter binds to human serum amyloid P-component and is present in brain amyloid plaques.
Mencarelli C, Bode GH, Losen M, Kulharia M, Molenaar PC, Veerhuis R, Steinbusch HW, De Baets MH, Nicolaes GA, Martinez-Martinez P.
J Biol Chem 287(18):14897-911. doi: 10.1074/jbc.M111.299545. 2012
9COL4A3BP
Inactivation of ceramide transfer protein during pro-apoptotic stress by Golgi disassembly and caspase cleavage.
Chandran S, Machamer CE.
Biochem J 442(2):391-401. doi: 10.1042/BJ20111461. 2012
10COL4A3BP, FILIP1L
Goodpasture antigen-binding protein (GPBP) directs myofibril formation: identification of intracellular downstream effector 130-kDa GPBP-interacting protein (GIP130).
Revert-Ros F, López-Pascual E, Granero-Moltó F, Macías J, Breyer R, Zent R, Hudson BG, Saadeddin A, Revert F, Blasco R, Navarro C, Burks D, Saus J.
J Biol Chem 286(40):35030-43. Epub 2011 Aug 9. 2011
11COL4A3BP
The intermembrane ceramide transport catalyzed by CERT is sensitive to the lipid environment.
Tuuf J, Kjellberg MA, Molotkovsky JG, Hanada K, Mattjus P.
Biochim Biophys Acta 1808(1):229-35. doi: 10.1016/j.bbamem.2010.09.011. 2011
12COL4A3BP
Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer.
Kudo N, Kumagai K, Matsubara R, Kobayashi S, Hanada K, Wakatsuki S, Kato R.
J Mol Biol 396(2):245-51. doi: 10.1016/j.jmb.2009.12.029. 2010
13COL4A3BP
The expression of the Goodpasture antigen-binding protein (ceramide transporter) in adult rat brain.
Mencarelli C, Hammels C, Van Den Broeck J, Losen M, Steinbusch H, Revert F, Saus J, Hopkins DA, De Baets MH, Steinbusch HW, Martinez-Martinez P.
J Chem Neuroanat 38(2):97-105. doi: 10.1016/j.jchemneu.2009.06.005. 2009
14COL4A3BP
Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice.
Wang X, Rao RP, Kosakowska-Cholody T, Masood MA, Southon E, Zhang H, Berthet C, Nagashim K, Veenstra TK, Tessarollo L, Acharya U, Acharya JK.
J Cell Biol 184(1):143-58. doi: 10.1083/jcb.200807176. 2009
15COL4A3, COL4A3BP
Goodpasture antigen-binding protein is a soluble exportable protein that interacts with type IV collagen. Identification of novel membrane-bound isoforms.
Revert F, Ventura I, Martínez-Martínez P, Granero-Moltó F, Revert-Ros F, Macías J, Saus J.
J Biol Chem 283(44):30246-55. Epub 2008 Sep 4.PMID: 18772132 2008
16COL4A3BP
Decreased ceramide transport protein (CERT) function alters sphingomyelin production following UVB irradiation.
Charruyer A, Bell SM, Kawano M, Douangpanya S, Yen TY, Macher BA, Kumagai K, Hanada K, Holleran WM, Uchida Y.
J Biol Chem 283(24):16682-92. Epub 2008 Apr 14.PMID: 1841126 2008
17COL4A3BP
Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide.
Kudo N, Kumagai K, Tomishige N, Yamaji T, Wakatsuki S, Nishijima M, Hanada K, Kato R.
Proc Natl Acad Sci U S A 105(2):488-93. Epub 2008 Jan 9.PMID: 18184806 2008
18COL4A3BP
Regulation of secretory transport by protein kinase D-mediated phosphorylation of the ceramide transfer protein.
Fugmann T, Hausser A, Schöffler P, Schmid S, Pfizenmaier K, Olayioye MA.
J Cell Biol 178(1):15-22. Epub 2007 Jun 25.PMID: 17591919 2007
19COL4A3BP
Interorganelle trafficking of ceramide is regulated by phosphorylation-dependent cooperativity between the PH and START domains of CERT.
Kumagai K, Kawano M, Shinkai-Ouchi F, Nishijima M, Hanada K.
J Biol Chem 282(24):17758-66. Epub 2007 Apr 18.PMID: 17442665 2007
20COL4A3BP
Efficient trafficking of ceramide from the endoplasmic reticulum to the Golgi apparatus requires a VAMP-associated protein-interacting FFAT motif of CERT.
Kawano M, Kumagai K, Nishijima M, Hanada K.
J Biol Chem 281(40):30279-88. Epub 2006 Aug 8.PMID: 16895911 2006
21COL4A3BP, PCTP, STAR, STARD10, STARD3, STARD5
Give lipids a START: the StAR-related lipid transfer (START) domain in mammals.
Alpy F, Tomasetto C.
J Cell Sci 118(Pt 13):2791-801. Review. 2005
22COL4A3BP
Goodpasture antigen-binding protein, the kinase that phosphorylates thegoodpasture antigen, is an alternatively spliced variant implicated inautoimmune pathogenesis.
Raya A, Revert-Ros F, Martinez-Martinez P, Navarro S, Rosello E, VieitesB, Granero F, Forteza J, Saus J.
J Biol Chem 275(51):40392-9. 2000
23COL4A3BP
Goodpasture syndrome.
Kalluri R.
Kidney Int 55(3):1120-2. Review. No abstract available. 1999
24COL4A3BP
Characterization of a novel type of serine/threonine kinase that specificallyphosphorylates the human goodpasture antigen.
Raya A, Revert F, Navarro S, Saus J.
J Biol Chem 274(18):12642-9. 1999