| 1 | CNOT6, CNOT6L, CNOT7, CNOT8
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| Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability.
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| Mostafa D, Takahashi A, Yanagiya A, Yamaguchi T, Abe T, Kureha T, Kuba K, Kanegae Y, Furuta Y, Yamamoto T, Suzuki T.
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| RNA Biol. Mar;17(3):403-416. doi: 10.1080/15476286.2019.1709747. Epub 2020 Jan 10 2020
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| 2 | CNOT6, CNOT6L, CNOT7, CNOT8
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| The enzyme activities of Caf1 and Ccr4 are both required for deadenylation by the human Ccr4-Not nuclease module.
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| Maryati M, Airhihen B, Winkler GS.
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| Biochem J. Jul 1;469(1):169-76. doi: 10.1042/BJ20150304. Epub 2015 May 6 2015
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| 3 | CNOT6, CNOT6L
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| The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence.
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| Mittal S, Aslam A, Doidge R, Medica R, Winkler GS.
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| Mol Biol Cell 22(6):748-58. Epub 2011 Jan 13.
2011
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| 4 | CNOT6, CNOT6L
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| Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.
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| Wang H, Morita M, Yang X, Suzuki T, Yang W, Wang J, Ito K, Wang Q, Zhao C, Bartlam M, Yamamoto T, Rao Z.
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| EMBO J 29(15):2566-76. Epub 2010 Jul 13.
2010
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| 5 | CNOT4, CNOT6, CNOT6L
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| Human Ccr4-Not complexes contain variable deadenylase subunits.
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| Lau NC, Kolkman A, van Schaik FM, Mulder KW, Pijnappel WW, Heck AJ, Timmers HT.
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| Biochem J 422(3):443-53.PMID: 19558367 2009
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| 6 | CNOT6L
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| Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth.
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| Morita M, Suzuki T, Nakamura T, Yokoyama K, Miyasaka T, Yamamoto T.
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| Mol Cell Biol 27(13):4980-90. Epub 2007 Apr 23.
2007
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| 7 | CNOT6, CNOT6L
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| BTG2 antiproliferative protein interacts with the human CCR4 complex existing in vivo in three cell-cycle-regulated forms.
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| Morel AP, Sentis S, Bianchin C, Le Romancer M, Jonard L, Rostan MC, Rimokh R, Corbo L.
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| J Cell Sci 116(Pt 14):2929-36. Epub 2003 May 27.
2003
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| 8 | CNOT2, CNOT3, CNOT4, CNOT6L, CNOT7, CNOT8
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| Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits.
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| Albert TK, Lemaire M, van Berkum NL, Gentz R, Collart MA, Timmers HT.
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| Nucleic Acids Res 28(3):809-17. 2000
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