Citations for
1CNOT1, DDNFA
De Novo Variants in CNOT1, a Central Component of the CCR4-NOT Complex Involved in Gene Expression and RNA and Protein Stability, Cause Neurodevelopmental Delay
Vissers LELM, Kalvakuri S, de Boer E, Geuer S, Oud M, van Outersterp I, Kwint M, Witmond M, Kersten S, Polla DL, Weijers D, Begtrup A, McWalter K, Ruiz A, Gabau E, Morton JEV, Griffith C, Weiss K, Gamble C, Bartley J, Vernon HJ, Brunet K, Ruivenkamp C, Kant SG, Kruszka P, Larson A, Afenjar A, Billette de Villemeur T, Nugent K; DDD Study, Raymond FL, Venselaar H, Demurger F, Soler-Alfonso C, Li D, Bhoj E, Hayes I, Hamilton NP, Ahmad A, Fisher R, van den Born M, Willems M, Sorlin A, Delanne J, Moutton S, Christophe P, Mau-Them FT, Vitobello A, Goel H, Massingham L, Phornphutkul C, Schwab J, Keren B, Charles P, Vreeburg M, De Simone L, Hoganson G, Iascone M, Milani D, Evenepoel L, Revencu N, Ward DI, Burns K, Krantz I, Raible SE, Murrell JR, Wood K, Cho MT, van Bokhoven H, Muenke M, Kleefstra T, Bodmer R, de Brouwer APM.
Am J Hum Genet. Jul 2;107(1):164-172. doi: 10.1016/j.ajhg.2020.05.017. Epub 2020 Jun 17 2020
2CNOT1, HPEAP
A Specific CNOT1 Mutation Results in a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development.
De Franco E, Watson RA, Weninger WJ, Wong CC, Flanagan SE, Caswell R, Green A, Tudor C, Lelliott CJ, Geyer SH, Maurer-Gesek B, Reissig LF, Lango Allen H, Caliebe A, Siebert R, Holterhus PM, Deeb A, Prin F, Hilbrands R, Heimberg H, Ellard S, Hattersley AT, Barroso I.
Am J Hum Genet 104(5):985-989. doi: 10.1016/j.ajhg.2019.03.018. Epub 2019 Apr 18. 2019
3CNOT1, HPEAP
A CCR4-NOT Transcription Complex, Subunit 1, CNOT1, Variant Associated with Holoprosencephaly.
Kruszka P, Berger SI, Weiss K, Everson JL, Martinez AF, Hong S, Anyane-Yeboa K, Lipinski RJ, Muenke M.
Am J Hum Genet 104(5):990-993. doi: 10.1016/j.ajhg.2019.03.017. Epub 2019 Apr 18. 2019
4ATG7, CNOT1, CNOT3
The CCR4-NOT deadenylase complex controls Atg7-dependent cell death and heart function.
Yamaguchi T, Suzuki T, Sato T, Takahashi A, Watanabe H, Kadowaki A, Natsui M, Inagaki H, Arakawa S, Nakaoka S, Koizumi Y, Seki S, Adachi S, Fukao A, Fujiwara T, Natsume T, Kimura A, Komatsu M, Shimizu S, Ito H, Suzuki Y, Penninger JM, Yamamoto T, Imai Y, Kuba K.
Sci Signal 11(516). pii: eaan3638. doi: 10.1126/scisignal.aan3638. 2018
5CNOT1, CNOT9
The central region of CNOT1 and CNOT9 stimulates deadenylation by the Ccr4-Not nuclease module.
Pavanello L, Hall B, Airhihen B, Winkler GS.
Biochem J 475(21):3437-3450. doi: 10.1042/BCJ20180456. 2018
6CNOT1, CNOT7, ICAM1, IL8
CNOT1 is involved in TTP‑mediated ICAM‑1 and IL‑8 mRNA decay.
Shi JX, Li JS, Hu R, Zhao XC, Liang CC, Li XM, Wang H, Shi Y, Su X.
Mol Med Rep 18(2):2321-2327. doi: 10.3892/mmr.2018.9213. Epub 2018 Jun 22. 2018
7CNOT1, LMNA
CNOT1 cooperates with LMNA to aggravate osteosarcoma tumorigenesis through the Hedgehog signaling pathway.
Cheng DD, Li J, Li SJ, Yang QC, Fan CY.
Mol Oncol 11(4):388-404. doi: 10.1002/1878-0261.12043. Epub 2017 Mar 6. 2017
8CNOT1, YTHDF2
YTHDF2 destabilizes m(6)A-containing RNA through direct recruitment of the CCR4-NOT deadenylase complex.
Du H, Zhao Y, He J, Zhang Y, Xi H, Liu M, Ma J, Wu L.
Nat Commun 7:12626. doi: 10.1038/ncomms12626. 2016
9CNOT1, DDX6, EDC3, EIF4ENIF1
Structure of a Human 4E-T/DDX6/CNOT1 Complex Reveals the Different Interplay of DDX6-Binding Proteins with the CCR4-NOT Complex.
Ozgur S, Basquin J, Kamenska A, Filipowicz W, Standart N, Conti E.
Cell Rep 13(4):703-11. doi: 10.1016/j.celrep.2015.09.033. Epub 2015 Oct 17. 2015
10CNOT1, DDX6
Human DDX6 effects miRNA-mediated gene silencing via direct binding to CNOT1.
Rouya C, Siddiqui N, Morita M, Duchaine TF, Fabian MR, Sonenberg N.
RNA 20(9):1398-409. doi: 10.1261/rna.045302.114. Epub 2014 Jul 17. 2014
11CNOT1, DDX6
Structural and biochemical insights to the role of the CCR4-NOT complex and DDX6 ATPase in microRNA repression.
Mathys H, Basquin J, Ozgur S, Czarnocki-Cieciura M, Bonneau F, Aartse A, Dziembowski A, Nowotny M, Conti E, Filipowicz W.
Mol Cell 54(5):751-65. doi: 10.1016/j.molcel.2014.03.036. Epub 2014 Apr 24. 2014
12CNOT1, CNOT2, CNOT3
Structure and assembly of the NOT module of the human CCR4-NOT complex.
Boland A, Chen Y, Raisch T, Jonas S, Kuzuoğlu-Öztürk D, Wohlbold L, Weichenrieder O, Izaurralde E.
Nat Struct Mol Biol 20(11):1289-97. doi: 10.1038/nsmb.2681. Epub 2013 Oct 13. 2013
13CNOT1, ZFP36
Structural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolin.
Fabian MR, Frank F, Rouya C, Siddiqui N, Lai WS, Karetnikov A, Blackshear PJ, Nagar B, Sonenberg N.
Nat Struct Mol Biol 20(6):735-9. doi: 10.1038/nsmb.2572. Epub 2013 May 5. 2013
14CNOT1, CNOT2, CNOT3
Cnot1, Cnot2, and Cnot3 maintain mouse and human ESC identity and inhibit extraembryonic differentiation.
Zheng X, Dumitru R, Lackford BL, Freudenberg JM, Singh AP, Archer TK, Jothi R, Hu G.
Stem Cells 30(5):910-22. doi: 10.1002/stem.1070. 2012
15CNOT1, CNOT2, CNOT3
Cnot1, Cnot2, and Cnot3 maintain mouse and human ESC identity and inhibit extraembryonic differentiation.
Zheng X, Dumitru R, Lackford BL, Freudenberg JM, Singh AP, Archer TK, Jothi R, Hu G.
Stem Cells 30(5):910-22. doi: 10.1002/stem.1070. 2012
16CNOT1
The role of the CNOT1 subunit of the CCR4-NOT complex in mRNA deadenylation and cell viability.
Ito K, Takahashi A, Morita M, Suzuki T, Yamamoto T.
Protein Cell 2(9):755-63. doi: 10.1007/s13238-011-1092-4. Epub 2011 Oct 6. 2011
17CNOT1, ESR1
Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcription.
Winkler GS, Mulder KW, Bardwell VJ, Kalkhoven E, Timmers HT.
EMBO J 25(13):3089-99. Epub 2006 Jun 15. 2006
18CNOT1, CNOT2, CNOT3
Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits.
Albert TK, Lemaire M, van Berkum NL, Gentz R, Collart MA, Timmers HT.
Nucleic Acids Res 28(3):809-17. 2000