1 | CLP1, PCH10
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| CLP1 as a novel player in linking tRNA splicing to neurodegenerative disorders.
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| Weitzer S, Hanada T, Penninger JM, Martinez J.
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| Wiley Interdiscip Rev RNA 6(1):47-63. doi: 10.1002/wrna.1255. Epub 2014 Aug 20. Review.
2015
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2 | CLP1, PCH10
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| CLP1 founder mutation links tRNA splicing and maturation to cerebellar development and neurodegeneration.
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| Schaffer AE, Eggens VR, Caglayan AO, Reuter MS, Scott E, Coufal NG, Silhavy JL, Xue Y, Kayserili H, Yasuno K, Rosti RO, Abdellateef M, Caglar C, Kasher PR, Cazemier JL, Weterman MA, Cantagrel V, Cai N, Zweier C, Altunoglu U, Satkin NB, Aktar F, Tuysuz B, Yalcinkaya C, Caksen H, Bilguvar K, Fu XD, Trotta CR, Gabriel S, Reis A, Gunel M, Baas F, Gleeson JG.
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| Cell 157(3):651-63. doi: 10.1016/j.cell.2014.03.049.
2014
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3 | CLP1, PCH10
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| Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function.
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| Karaca E, Weitzer S, Pehlivan D, Shiraishi H, Gogakos T, Hanada T, Jhangiani SN, Wiszniewski W, Withers M, Campbell IM, Erdin S, Isikay S, Franco LM, Gonzaga-Jauregui C, Gambin T, Gelowani V, Hunter JV, Yesil G, Koparir E, Yilmaz S, Brown M, Briskin D, Hafner M, Morozov P, Farazi TA, Bernreuther C, Glatzel M, Trattnig S, Friske J, Kronnerwetter C, Bainbridge MN, Gezdirici A, Seven M, Muzny DM, Boerwinkle E, Ozen M; Baylor Hopkins Center for Mendelian Genomics, Clausen T, Tuschl T, Yuksel A, Hess A, Gibbs RA, Martinez J, Penninger JM, Lupski JR.
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| Cell 157(3):636-50. doi: 10.1016/j.cell.2014.02.058.
2014
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4 | CLP1
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| RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase Clp1.
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| Dikfidan A, Loll B, Zeymer C, Magler I, Clausen T, Meinhart A.
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| Mol Cell 54(6):975-86. doi: 10.1016/j.molcel.2014.04.005. Epub 2014 May 8.
2014
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5 | CLP1
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| CLP1 links tRNA metabolism to progressive motor-neuron loss.
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| Hanada T, Weitzer S, Mair B, Bernreuther C, Wainger BJ, Ichida J, Hanada R, Orthofer M, Cronin SJ, Komnenovic V, Minis A, Sato F, Mimata H, Yoshimura A, Tamir I, Rainer J, Kofler R, Yaron A, Eggan KC, Woolf CJ, Glatzel M, Herbst R, Martinez J, Penninger JM.
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| Nature 495(7442):474-80. doi: 10.1038/nature11923. Epub 2013 Mar 10.
2013
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6 | CLP1
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| The human RNA kinase hClp1 is active on 3' transfer RNA exons and short interfering RNAs.
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| Weitzer S, Martinez J.
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| Nature 447(7141):222-6.
2007
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7 | CLP1, TSEN15, TSEN2, TSEN34, TSEN54
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| Identification of a human endonuclease complex reveals a link between tRNA splicing and pre-mRNA 3' end formation.
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| Paushkin SV, Patel M, Furia BS, Peltz SW, Trotta CR.
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| Cell 117(3):311-21. 2004
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8 | CLP1, KMT2A, MLLT10
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| AF10 is split by MLL and HEAB, a human homolog to a putative Caenorhabditis elegans ATP/GTP-binding protein in an invins(10;11)(p12;q23q12).
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| Tanabe S, et al.
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| Blood 88 : 3535-3545. 1996
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