Citations for
1CLP1, PCH10
CLP1 as a novel player in linking tRNA splicing to neurodegenerative disorders.
Weitzer S, Hanada T, Penninger JM, Martinez J.
Wiley Interdiscip Rev RNA 6(1):47-63. doi: 10.1002/wrna.1255. Epub 2014 Aug 20. Review. 2015
2CLP1, PCH10
CLP1 founder mutation links tRNA splicing and maturation to cerebellar development and neurodegeneration.
Schaffer AE, Eggens VR, Caglayan AO, Reuter MS, Scott E, Coufal NG, Silhavy JL, Xue Y, Kayserili H, Yasuno K, Rosti RO, Abdellateef M, Caglar C, Kasher PR, Cazemier JL, Weterman MA, Cantagrel V, Cai N, Zweier C, Altunoglu U, Satkin NB, Aktar F, Tuysuz B, Yalcinkaya C, Caksen H, Bilguvar K, Fu XD, Trotta CR, Gabriel S, Reis A, Gunel M, Baas F, Gleeson JG.
Cell 157(3):651-63. doi: 10.1016/j.cell.2014.03.049. 2014
3CLP1, PCH10
Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function.
Karaca E, Weitzer S, Pehlivan D, Shiraishi H, Gogakos T, Hanada T, Jhangiani SN, Wiszniewski W, Withers M, Campbell IM, Erdin S, Isikay S, Franco LM, Gonzaga-Jauregui C, Gambin T, Gelowani V, Hunter JV, Yesil G, Koparir E, Yilmaz S, Brown M, Briskin D, Hafner M, Morozov P, Farazi TA, Bernreuther C, Glatzel M, Trattnig S, Friske J, Kronnerwetter C, Bainbridge MN, Gezdirici A, Seven M, Muzny DM, Boerwinkle E, Ozen M; Baylor Hopkins Center for Mendelian Genomics, Clausen T, Tuschl T, Yuksel A, Hess A, Gibbs RA, Martinez J, Penninger JM, Lupski JR.
Cell 157(3):636-50. doi: 10.1016/j.cell.2014.02.058. 2014
4CLP1
RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase Clp1.
Dikfidan A, Loll B, Zeymer C, Magler I, Clausen T, Meinhart A.
Mol Cell 54(6):975-86. doi: 10.1016/j.molcel.2014.04.005. Epub 2014 May 8. 2014
5CLP1
CLP1 links tRNA metabolism to progressive motor-neuron loss.
Hanada T, Weitzer S, Mair B, Bernreuther C, Wainger BJ, Ichida J, Hanada R, Orthofer M, Cronin SJ, Komnenovic V, Minis A, Sato F, Mimata H, Yoshimura A, Tamir I, Rainer J, Kofler R, Yaron A, Eggan KC, Woolf CJ, Glatzel M, Herbst R, Martinez J, Penninger JM.
Nature 495(7442):474-80. doi: 10.1038/nature11923. Epub 2013 Mar 10. 2013
6CLP1
The human RNA kinase hClp1 is active on 3' transfer RNA exons and short interfering RNAs.
Weitzer S, Martinez J.
Nature 447(7141):222-6. 2007
7CLP1, TSEN15, TSEN2, TSEN34, TSEN54
Identification of a human endonuclease complex reveals a link between tRNA splicing and pre-mRNA 3' end formation.
Paushkin SV, Patel M, Furia BS, Peltz SW, Trotta CR.
Cell 117(3):311-21. 2004
8CLP1, KMT2A, MLLT10
AF10 is split by MLL and HEAB, a human homolog to a putative Caenorhabditis elegans ATP/GTP-binding protein in an invins(10;11)(p12;q23q12).
Tanabe S, et al.
Blood 88 : 3535-3545. 1996