| 1 | CLDN3, CLDN4, REG1A
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| Role of regenerating gene I in claudin expression and barrier function in the small intestine.
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| Kitayama Y, Fukui H, Hara K, Eda H, Kodani M, Yang M, Sun C, Yamagishi H, Tomita T, Oshima T, Watari J, Takasawa S, Miwa H.
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| Transl Res. Jul;173:92-100. doi: 10.1016/j.trsl.2016.03.007. Epub 2016 Mar 19. 2016
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| 2 | CLDN2, CLDN4, EGF
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| EGF regulates claudin-2 and -4 expression through Src and STAT3 in MDCK cells.
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| García-Hernández V, Flores-Maldonado C, Rincon-Heredia R, Verdejo-Torres O, Bonilla-Delgado J, Meneses-Morales I, Gariglio P, Contreras RG.
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| J Cell Physiol 230(1):105-15. doi: 10.1002/jcp.24687.
2015
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| 3 | CLDN4, GRHL2, OVOL2, RAB25
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| A Grainyhead-Like 2/Ovo-Like 2 Pathway Regulates Renal Epithelial Barrier Function and Lumen Expansion.
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| Aue A, Hinze C, Walentin K, Ruffert J, Yurtdas Y, Werth M, Chen W, Rabien A, Kilic E, Schulzke JD, Schumann M, Schmidt-Ott KM.
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| J Am Soc Nephrol Am Soc Nephrol. 2015 Mar 18. pii: ASN.2014080759. [Epub ahead of print]
2015
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| 4 | CLDN4, FUT4
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| Genome-wide DNA methylation identifies trophoblast invasion-related genes: Claudin-4 and Fucosyltransferase IV control mobility via altering matrix metalloproteinase activity.
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| Hu Y, Blair JD, Yuen RK, Robinson WP, von Dadelszen P.
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| Mol Hum Reprod. May;21(5):452-65. doi: 10.1093/molehr/gav007. Epub 2015 Feb 19 2015
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| 5 | CLDN4, EPHA2
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| Claudin-4 controls the receptor tyrosine kinase EphA2 pro-oncogenic switch through ß-catenin.
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| Shang X, Lin X, Howell SB.
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| Cell Commun Signal 12(1):59. [Epub ahead of print]
2014
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| 6 | CLDN3, CLDN4
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| Development of an anti-claudin-3 and -4 bispecific monoclonal antibody for cancer diagnosis and therapy.
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| Li X, Iida M, Tada M, Watari A, Kawahigashi Y, Kimura Y, Yamashita T, Ishii-Watabe A, Uno T, Fukasawa M, Kuniyasu H, Yagi K, Kondoh M.
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| J Pharmacol Exp Ther 351(1):206-13. doi: 10.1124/jpet.114.216911. Epub 2014 Aug 12.
2014
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| 7 | CLDN1, CLDN4, TWIST1, ZEB1
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| A survey of zeb1, twist and claudin 1 and 4 expression during placental development and disease.
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| Pirinen E, Soini Y.
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| APMIS 122(6):530-8. doi: 10.1111/apm.12187. Epub 2013 Dec 5.
2014
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| 8 | CLDN1, CLDN2, CLDN3, CLDN4
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| Claudins 1, 2, 3, 4, 5 and 7 in solar keratosis and squamocellular carcinoma of the skin.
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| Hintsala HR, Siponen M, Haapasaari KM, Karihtala P, Soini Y.
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| Int J Clin Exp Pathol 6(12):2855-63. eCollection 2013.
2013
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| 9 | CLDN4
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| Claudin-4 as a marker for distinguishing malignant mesothelioma from lung carcinoma and serous adenocarcinoma.
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| Ohta Y, Sasaki Y, Saito M, Kushima M, Takimoto M, Shiokawa A, Ota H.
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| Int J Surg Pathol 21(5):493-501. doi: 10.1177/1066896913491320. Epub 2013 Jun 17.
2013
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| 10 | CLDN4
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| Value of claudin-4 immunostaining in the diagnosis of mesothelioma.
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| Ordóñez NG.
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| Am J Clin Pathol 139(5):611-9. doi: 10.1309/AJCP0B3YJBXWXJII.
2013
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| 11 | CLDN4, TWIST1
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| Twist1 causes the transcriptional repression of claudin-4 with prognostic significance in esophageal cancer.
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| Lee KW, Lee NK, Kim JH, Kang MS, Yoo HY, Kim HH, Um SH, Kim SH.
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| Biochem Biophys Res Commun 423(3):454-60. doi: 10.1016/j.bbrc.2012.05.140. Epub 2012 Jun 2.
2012
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| 12 | CLDN4
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| Claudin-4 deficiency results in urothelial hyperplasia and lethal hydronephrosis.
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| Fujita H, Hamazaki Y, Noda Y, Oshima M, Minato N.
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| PLoS One 7(12):e52272. doi: 10.1371/journal.pone.0052272. Epub 2012 Dec 21.
2012
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| 13 | CLDN3, CLDN4
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| Tight junction proteins claudin-3 and claudin-4 control tumor growth and metastases.
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| Shang X, Lin X, Alvarez E, Manorek G, Howell SB.
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| Neoplasia 14(10):974-85.
2012
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| 14 | CLDN3, CLDN4, GRHL2, RAB25
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| Grainyhead-like 2 regulates epithelial morphogenesis by establishing functional tight junctions through the organization of a molecular network among claudin3, claudin4, and Rab25.
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| Senga K, Mostov KE, Mitaka T, Miyajima A, Tanimizu N.
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| Mol Biol Cell 23(15):2845-55. doi: 10.1091/mbc.E12-02-0097. Epub 2012 Jun 13.
2012
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| 15 | CLDN4
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| Claudin-4 as therapeutic target in cancer.
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| Neesse A, Griesmann H, Gress TM, Michl P.
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| Arch Biochem Biophys 524(1):64-70. doi: 10.1016/j.abb.2012.01.009. Epub 2012 Jan 24. Review.
2012
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| 16 | CLDN1, CLDN3, CLDN4
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| Enhancement of cell-cell contact by claudin-4 in renal epithelial Madin-Darby canine kidney cells.
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| Ikari A, Atomi K, Takiguchi A, Yamazaki Y, Hayashi H, Hirakawa J, Sugatani J.
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| J Cell Biochem 113(2):499-507. doi: 10.1002/jcb.23373.
2012
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| 17 | CLDN1, CLDN10, CLDN4
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| Role of microRNAs in controlling gene expression in different segments of the human epididymis.
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| Belleannée C, Calvo E, Thimon V, Cyr DG, Légaré C, Garneau L, Sullivan R.
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| PLoS One 7(4):e34996. doi: 10.1371/journal.pone.0034996. Epub 2012 Apr 12.
2012
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| 18 | CLDN16, CLDN2, CLDN4
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| Claudin-2 forms homodimers and is a component of a high molecular weight protein complex.
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| Van Itallie CM, Mitic LL, Anderson JM.
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| J Biol Chem 286(5):3442-50. Epub 2010 Nov 22.
2011
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| 19 | CLDN4
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| Claudin-4 induction by E-protein activity in later stages of CD4/8 double-positive thymocytes to increase positive selection efficiency.
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| Kawai Y, Hamazaki Y, Fujita H, Fujita A, Sato T, Furuse M, Fujimoto T, Jetten AM, Agata Y, Minato N.
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| Proc Natl Acad Sci U S A 108(10):4075-80. Epub 2011 Feb 15.
2011
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| 20 | CLDN3, CLDN4
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| Differential effects of claudin-3 and claudin-4 on alveolar epithelial barrier function.
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| Mitchell LA, Overgaard CE, Ward C, Margulies SS, Koval M.
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| Am J Physiol Lung Cell Mol Physiol 301(1):L40-9. doi: 10.1152/ajplung.00299.2010. Epub 2011 Apr 22.
2011
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| 21 | CLDN4
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| Low expression of claudin-4 is associated with poor prognosis in esophageal squamous cell carcinoma.
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| Sung CO, Han SY, Kim SH.
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| Ann Surg Oncol 18(1):273-81. doi: 10.1245/s10434-010-1289-4. Epub 2010 Sep 14.
2011
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| 22 | CLDN3, CLDN4, CLDN7, CLDN8
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| Claudin-4 forms paracellular chloride channel in the kidney and requires claudin-8 for tight junction localization.
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| Hou J, Renigunta A, Yang J, Waldegger S.
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| Proc Natl Acad Sci U S A 107(42):18010-5. Epub 2010 Oct 4.
2010
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| 23 | CLDN4
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| E-cadherin and claudin-4 expression has circadian rhythm in adult rat kidney.
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| Yamato M, Ito T, Iwatani H, Yamato M, Imai E, Rakugi H.
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| J Nephrol 23(1):102-10.
2010
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| 24 | CLDN3, CLDN4
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| Claudin-3 gene silencing with siRNA suppresses ovarian tumor growth and metastasis.
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| Huang YH, Bao Y, Peng W, Goldberg M, Love K, Bumcrot DA, Cole G, Langer R, Anderson DG, Sawicki JA.
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| Proc Natl Acad Sci U S A 106(9):3426-30. Epub 2009 Feb 10. 2009
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| 25 | CLDN1, CLDN3, CLDN4
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| Expression of tight and adherens junction proteins in ulcerative colitis associated colorectal carcinoma: upregulation of claudin-1, claudin-3, claudin-4, and beta-catenin.
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| Mees ST, Mennigen R, Spieker T, Rijcken E, Senninger N, Haier J, Bruewer M.
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| Int J Colorectal Dis 24(4):361-8. Epub 2009 Jan 29.
2009
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| 26 | CLDN4, LIF
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| Endometrial claudin-4 and leukemia inhibitory factor are associated with assisted reproduction outcome.
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| Serafini PC, Silva ID, Smith GD, Motta EL, Rocha AM, Baracat EC.
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| Reprod Biol Endocrinol 7:30.
2009
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| 27 | CLDN4
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| Identification of claudin-4 as a marker highly overexpressed in both primary and metastatic prostate cancer.
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| Landers KA, Samaratunga H, Teng L, Buck M, Burger MJ, Scells B, Lavin MF, Gardiner RA.
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| Br J Cancer 99(3):491-501. Epub 2008 Jul 22.PMID: 18648369 2008
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| 28 | CLDN3, CLDN4
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| Expression profile of tight junction protein claudin 3 and claudin 4 in ovarian serous adenocarcinoma with prognostic correlation.
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| Choi YL, Kim J, Kwon MJ, Choi JS, Kim TJ, Bae DS, Koh SS, In YH, Park YW, Kim SH, Ahn G, Shin YK.
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| Histol Histopathol 22(11):1185-95.
2007
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| 29 | CLDN4
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| Differential expression of claudin-4 between intestinal and diffuse-type gastric cancer.
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| Kuo WL, Lee LY, Wu CM, Wang CC, Yu JS, Liang Y, Lo CH, Huang KH, Hwang TL.
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| Oncol Rep 16(4):729-34.
2006
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| 30 | EPHA2, CLDN4
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| EphA2 phosphorylates the cytoplasmic tail of Claudin-4 and mediates paracellular permeability.
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| Tanaka M, Kamata R, Sakai R.
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| J Biol Chem 280(51):42375-82. Epub 2005 Oct 18. 2005
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| 31 | CLDN4
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| Claudin-4 expression decreases invasiveness and metastatic potential of pancreatic cancer.
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| Michl P, Barth C, Buchholz M, Lerch MM, Rolke M, Holzmann KH, Menke A, Fensterer H, Giehl K, Lohr M, Leder G, Iwamura T, Adler G, Gress TM.
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| Cancer Res 63(19):6265-71. 2003
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| 32 | CLDN1, CLDN10, CLDN11, CLDN12, CLDN14, CLDN15, CLDN16, CLDN17, CLDN18, CLDN19, CLDN2, CLDN20, CLDN21, CLDN22, CLDN3, CLDN4, CLDN5, CLDN6, CLDN7, CLDN8, CLDN9
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| Claudins create charge-selective channels in the paracellular pathway between epithelial cells.
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| Colegio OR, Van Itallie CM, McCrea HJ, Rahner C, Anderson JM.
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| Am J Physiol Cell Physiol 283(1):C142-7. 2002
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| 33 | WBS, CLDN3, CLDN4
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| A complete physical contig and partial transcript map of the williams syndrome critical region.
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| Hockenhull EL, et al.
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| Genomics 58(2):138-45. 1999
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| 34 | CLDN1, CLDN2, CLDN3, CLDN4, CLDN5, CLDN6, CLDN7, CLDN8, CLDN9
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| Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands.
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| Morita K, Furuse M, Fujimoto K, Tsukita S.
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| Proc Natl Acad Sci U S A 96(2):511-6. 1999
|