| 1 | CLDN2, IL22
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| IL-22 Increases Permeability of Intestinal Epithelial Tight Junctions by Enhancing Claudin-2 Expression.
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| Wang Y, Mumm JB, Herbst R, Kolbeck R, Wang Y.
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| J Immunol 199(9):3316-3325. doi: 10.4049/jimmunol.1700152. Epub 2017 Sep 22.
2017
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| 2 | CLDN2, CLDN4, EGF
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| EGF regulates claudin-2 and -4 expression through Src and STAT3 in MDCK cells.
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| García-Hernández V, Flores-Maldonado C, Rincon-Heredia R, Verdejo-Torres O, Bonilla-Delgado J, Meneses-Morales I, Gariglio P, Contreras RG.
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| J Cell Physiol 230(1):105-15. doi: 10.1002/jcp.24687.
2015
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| 3 | CLDN1, CLDN2, CLDN3, CLDN4
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| Claudins 1, 2, 3, 4, 5 and 7 in solar keratosis and squamocellular carcinoma of the skin.
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| Hintsala HR, Siponen M, Haapasaari KM, Karihtala P, Soini Y.
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| Int J Clin Exp Pathol 6(12):2855-63. eCollection 2013.
2013
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| 4 | CLDN2, MYLK
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| Claudin-2 regulates colorectal inflammation via myosin light chain kinase-dependent signaling.
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| Nishida M, Yoshida M, Nishiumi S, Furuse M, Azuma T.
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| Dig Dis Sci 58(6):1546-59. doi: 10.1007/s10620-012-2535-3. Epub 2013 Jan 11.
2013
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| 5 | CLDN2
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| Claudin-2 promotes breast cancer liver metastasis by facilitating tumor cell interactions with hepatocytes.
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| Tabariès S, Dupuy F, Dong Z, Monast A, Annis MG, Spicer J, Ferri LE, Omeroglu A, Basik M, Amir E, Clemons M, Siegel PM.
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| Mol Cell Biol 32(15):2979-91. doi: 10.1128/MCB.00299-12. Epub 2012 May 29.
2012
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| 6 | CLDN16, CLDN2, CLDN4
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| Claudin-2 forms homodimers and is a component of a high molecular weight protein complex.
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| Van Itallie CM, Mitic LL, Anderson JM.
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| J Biol Chem 286(5):3442-50. Epub 2010 Nov 22.
2011
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| 7 | CDX2, CLDN2, IL6
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| Interleukin-6 (IL-6) regulates claudin-2 expression and tight junction permeability in intestinal epithelium.
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| Suzuki T, Yoshinaga N, Tanabe S.
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| J Biol Chem 286(36):31263-71. Epub 2011 Jul 19. 2011
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| 8 | CLDN2
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| Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation.
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| Dhawan P, Ahmad R, Chaturvedi R, Smith JJ, Midha R, Mittal MK, Krishnan M, Chen X, Eschrich S, Yeatman TJ, Harris RC, Washington MK, Wilson KT, Beauchamp RD, Singh AB.
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| Oncogene 30(29):3234-47. doi: 10.1038/onc.2011.43. Epub 2011 Mar 7.
2011
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| 9 | CLDN2, CSDA, SYMPK
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| Symplekin promotes tumorigenicity by up-regulating claudin-2 expression.
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| Buchert M, Papin M, Bonnans C, Darido C, Raye WS, Garambois V, Pélegrin A, Bourgaux JF, Pannequin J, Joubert D, Hollande F.
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| Proc Natl Acad Sci U S A 107(6):2628-33. Epub 2010 Jan 25.PMID: 20133805 2010
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| 10 | CLDN2
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| Downregulation of claudin-2 expression in renal epithelial cells by metabolic acidosis.
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| Balkovetz DF, Chumley P, Amlal H.
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| Am J Physiol Renal Physiol 297(3):F604-11. Epub 2009 Jul 8.
2009
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| 11 | CLDN2
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| Molecular basis for cation selectivity in claudin-2-based pores.
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| Yu AS.
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| Ann N Y Acad Sci 1165:53-7.
2009
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| 12 | CLDN2, RPS6KA6
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| Anti-invasive and antimetastatic activities of ribosomal protein S6 kinase 4 in breast cancer cells.
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| Thakur A, Sun Y, Bollig A, Wu J, Biliran H, Banerjee S, Sarkar FH, Liao DJ.
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| Clin Cancer Res 14(14):4427-36.
2008
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| 13 | CLDN1, CLDN2
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| Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation.
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| Weber CR, Nalle SC, Tretiakova M, Rubin DT, Turner JR.
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| Lab Invest 88(10):1110-20. Epub 2008 Aug 18.
2008
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| 14 | CLDN2
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| Claudin 2 mRNA and protein are present in human keratinocytes and may be regulated by all-trans-retinoic acid.
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| Telgenhoff D, Ramsay S, Hilz S, Slusarewicz P, Shroot B.
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| Skin Pharmacol Physiol 21(4):211-7. Epub 2008 May 29.
2008
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| 15 | CLDN2
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| Expression of claudin-2 in the multistage process of gastric carcinogenesis.
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| Song X, Li X, Tang Y, Chen H, Wong B, Wang J, Chen M.
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| Histol Histopathol 23(6):673-82.
2008
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| 16 | CLDN12, CLDN2
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| Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes.
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| Fujita H, Sugimoto K, Inatomi S, Maeda T, Osanai M, Uchiyama Y, Yamamoto Y, Wada T, Kojima T, Yokozaki H, Yamashita T, Kato S, Sawada N, Chiba H.
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| Mol Biol Cell 19(5):1912-21. Epub 2008 Feb 20.PMID: 18287530 2008
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| 17 | CLDN2, RBBP7, RPS6KA6
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| Aberrant expression of X-linked genes RbAp46, Rsk4, and Cldn2 in breast cancer.
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| Thakur A, Rahman KW, Wu J, Bollig A, Biliran H, Lin X, Nassar H, Grignon DJ, Sarkar FH, Liao JD.
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| Mol Cancer Res 5(2):171-81.
2007
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| 18 | CLDN1, CLDN2
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| Selective up-regulation of claudin-1 and claudin-2 in colorectal cancer.
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| Kinugasa T, Huo Q, Higashi D, Shibaguchi H, Kuroki M, Tanaka T, Futami K, Yamashita Y, Hachimine K, Maekawa S, Nabeshima K, Iwasaki H, Kuroki M.
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| Anticancer Res 27(6A):3729-34.PMID: 17970035 2007
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| 19 | CLDN1, CLDN12, CLDN14, CLDN18, CLDN2, CLDN3, CLDN6, CLDN8, CLDN9
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| Expression patterns of claudins, tight junction adhesion molecules, in the inner ear.
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| Kitajiri SI, Furuse M, Morita K, Saishin-Kiuchi Y, Kido H, Ito J, Tsukita S.
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| Hear Res 187(1-2):25-34.PMID: 14698084 2004
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| 20 | CLDN2
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| Cloning of the human claudin-2 5'-flanking region revealed a TATA-less promoter with conserved binding sites in mouse and human for caudal-related homeodomain proteins and hepatocyte nuclear factor-1alpha.
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| Sakaguchi T, Gu X, Golden HM, Suh E, Rhoads DB, Reinecker HC.
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| J Biol Chem 277(24):21361-70. 2002
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| 21 | CLDN1, CLDN10, CLDN11, CLDN12, CLDN14, CLDN15, CLDN16, CLDN17, CLDN18, CLDN19, CLDN2, CLDN20, CLDN21, CLDN22, CLDN3, CLDN4, CLDN5, CLDN6, CLDN7, CLDN8, CLDN9
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| Claudins create charge-selective channels in the paracellular pathway between epithelial cells.
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| Colegio OR, Van Itallie CM, McCrea HJ, Rahner C, Anderson JM.
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| Am J Physiol Cell Physiol 283(1):C142-7. 2002
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| 22 | CLDN1, CLDN2, CLDN3, CLDN4, CLDN5, CLDN6, CLDN7, CLDN8, CLDN9
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| Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands.
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| Morita K, Furuse M, Fujimoto K, Tsukita S.
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| Proc Natl Acad Sci U S A 96(2):511-6. 1999
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| 23 | CLDN1, CLDN10, CLDN2, CLDN3
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| Ca(2+)-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions.
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| Kubota K, Furuse M, Sasaki H, Sonoda N, Fujita K, Nagafuchi A, Tsukita S.
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| Curr Biol 9(18):1035-8. 1999
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| 24 | CLDN2, HNRNPAB, PWP1
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| A pancreatic cancer-specific expression profile.
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| Gress TM, Muller-Pillasch F, Geng M, Zimmerhackl F, Zehetner G, Friess H,Buchler M, Adler G, Lehrach H.
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| Oncogene 13(8):1819-30. 1996
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