Citations for
Role of 1q21 in Multiple Myeloma: From Pathogenesis to Possible Therapeutic Targets
Burroughs Garcěa J, Eufemiese RA, Storti P, Sammarelli G, Craviotto L, Todaro G, Toscani D, Marchica V, Giuliani N.
Cells. Jun 1;10(6):1360. doi: 10.3390/cells10061360 2021
The survival impact of CKS1B gains or amplification is dependent on the background karyotype and TP53 deletion status in patients with myeloma
Hao S, Lu X, Gong Z, Bassett RL, Hu S, Konoplev SN, Tang G, Li S, Xu J, Khanlari M, Lee HC, Manasanch EE, Weber DM, Orlowski RZ, Medeiros LJ, Lin P.
Mod Pathol. Feb;34(2):327-335. doi: 10.1038/s41379-020-00669-7. Epub 2020 Sep 9 2021
CKS1B as Drug Resistance-Inducing Gene-A Potential Target to Improve Cancer Therapy
Shi W, Huang Q, Xie J, Wang H, Yu X, Zhou Y.
Front Oncol. Sep 25;10:582451. doi: 10.3389/fonc.2020.582451 2020
Downregulation of CKS1B restrains the proliferation, migration, invasion and angiogenesis of retinoblastoma cells through the MEK/ERK signaling pathway.
Zeng Z, Gao ZL, Zhang ZP, Jiang HB, Yang CQ, Yang J, Xia XB.
Int J Mol Med. Jul;44(1):103-114. doi: 10.3892/ijmm.2019.4183. Epub 2019 May 8 2019
CKS1B amplification is a frequent event in cutaneous squamous cell carcinoma with aggressive clinical behaviour.
Salgado R, Toll A, Alameda F, Baró T, Martín-Ezquerra G, Sanmartín O, Martorell-Calatayud A, Salido M, Almenar S, Solé F, Pujol RM, Espinet B.
Genes Chromosomes Cancer 49(11):1054-61. 2010
Role of Cks1 amplification and overexpression in breast cancer.
Wang XC, Tian J, Tian LL, Wu HL, Meng AM, Ma TH, Xiao J, Xiao XL, Li CH.
Biochem Biophys Res Commun 379(4):1107-13. Epub 2009 Jan 20. 2009
Expression of cyclin-dependent kinase subunit 1 (Cks1) is regulated during the cell cycle by a CDE/CHR tandem element and is downregulated by p53 but not by p63 or p73.
Rother K, Li YY, Tschöp K, Kirschner R, Müller GA, Mössner J, Engeland K.
Cell Cycle 6(7):853-62. Epub 2007 Apr 14. 2007
CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms.
Zhan F, Colla S, Wu X, Chen B, Stewart JP, Kuehl WM, Barlogie B, Shaughnessy JD Jr.
Blood 109(11):4995-5001. Epub 2007 Feb 15. 2007
Amplification and overexpression of CKS1B at chromosome band 1q21 is associated with reduced levels of p27Kip1 and an aggressive clinical course in multiple myeloma.
Shaughnessy J.
Hematology 10 Suppl 1:117-26. 2005
Inhibition of F-Box protein p45(SKP2) expression and stabilization of cyclin-dependent kinase inhibitor p27(KIP1) in vitamin D analog-treated cancer cells.
Lin R, Wang TT, Miller WH Jr, White JH.
Endocrinology 144(3):749-53. 2003
Cell Cycle Alterations in the Blastoid Variant of Mantle Cell Lymphoma (MCL-BV) as Detected by Gene Expression Profiling of Mantle Cell Lymphoma (MCL) and MCL-BV.
De Vos S, Krug U, Hofmann WK, Pinkus GS, Swerdlow SH, Wachsman W, Grogan TM, Said JW, Koeffler HP.
Diagn Mol Pathol 12(1):35-43. 2003
Loss of Mitotic Spindle Checkpoint Activity Predisposes to Chromosomal Instability at Early Stages of Fibrosarcoma Development.
Gascoyne DM, Hixon ML, Gualberto A, Vivanco MD.
Cell Cycle 2(3):238-245. 2003
Weak cooperativity in the core causes a switch in folding mechanism between two proteins of the cks family.
Seeliger MA, Breward SE, Itzhaki LS.
J Mol Biol 325(1):189-99. 2003
High expression of Cks1 in human non-small cell lung carcinomas.
Inui N, Kitagawa K, Miwa S, Hattori T, Chida K, Nakamura H, Kitagawa M.
Biochem Biophys Res Commun 303(3):978-84. 2003
Three different binding sites of Cks1 are required for p27-ubiquitin ligation.
Sitry D, Seeliger MA, Ko TK, Ganoth D, Breward SE, Itzhaki LS, Pagano M, Hershko A.
J Biol Chem 277(44):42233-40. Epub 2002 Jul 24. 2002
The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27.
Ganoth D, Bornstein G, Ko TK, Larsen B, Tyers M, Pagano M, Hershko A.
Nat Cell Biol 3(3):321-4. 2001
Crystal structure and mutational analysis of the human CDK2 kinase complex withcell cycle-regulatory protein CksHs1.
Bourne Y, Watson MH, Hickey MJ, Holmes W, Rocque W, Reed SI, Tainer JA.
Cell 84(6):863-74. 1996
Chromosomal mapping of the human genes CKS1 to 8q21 and CKS2 to 9q22.
Demetrick DJ, Zhang H, Beach DH.
Cytogenet Cell Genet 73(3):250-4. 1996
Transforming growth factor beta down-regulation of CKShs1 transcripts in growth-inhibited epithelial cells.
Simon KE, Cha HH, Firestone GL.
Cell Growth Differ 6(10):1261-9. 1995
Human cDNAs encoding homologs of the small p34Cdc28/Cdc2-associated protein ofSaccharomyces cerevisiae and Schizosaccharomyces pombe.
Richardson HE, Stueland CS, Thomas J, Russell P, Reed SI.
Genes Dev 4(8):1332-44. 1990