| 1 | CHRNA6, CHRNB3, CYP2A6
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| Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.
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| Thorgeirsson TE, Gudbjartsson DF, Surakka I, Vink JM, Amin N, Geller F, Sulem P, Rafnar T, Esko T, Walter S, Gieger C, Rawal R, Mangino M, Prokopenko I, Mägi R, Keskitalo K, Gudjonsdottir IH, Gretarsdottir S, Stefansson H, Thompson JR, Aulchenko YS, Nelis M, Aben KK, den Heijer M, Dirksen A, Ashraf H, Soranzo N, Valdes AM, Steves C, Uitterlinden AG, Hofman A, Tönjes A, Kovacs P, Hottenga JJ, Willemsen G, Vogelzangs N, Döring A, Dahmen N, Nitz B, Pergadia ML, Saez B, De Diego V, Lezcano V, Garcia-Prats MD, Ripatti S, Perola M, Kettunen J, Hartikainen AL, Pouta A, Laitinen J, Isohanni M, Huei-Yi S, Allen M, Krestyaninova M, Hall AS, Jones GT, van Rij AM, Mueller T, Dieplinger B, Haltmayer M, Jonsson S, Matthiasson SE, Oskarsson H, Tyrfingsson T, Kiemeney LA, Mayordomo JI, Lindholt JS, Pedersen JH, Franklin WA, Wolf H, Montgomery GW, Heath AC, Martin NG, Madden PA, Giegling I, Rujescu D, Järvelin MR, Salomaa V, Stumvoll M, Spector TD, Wichmann HE, Metspalu A, Samani NJ, Penninx BW, Oostra BA, Boomsma DI, Tiemeier H, van Duijn CM, Kaprio J, Gulcher JR; ENGAGE Consortium, McCarthy MI, Peltonen L, Thorsteinsdottir U, Stefansson K.
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| Nat Genet 42(5):448-53. Epub 2010 Apr 25.
2010
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| 2 | CHRNA6, CHRNB3
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| Association of nAChR gene haplotypes with heavy alcohol use and body mass.
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| Landgren S, Engel JA, Andersson ME, Gonzalez-Quintela A, Campos J, Nilsson S, Zetterberg H, Blennow K, Jerlhag E.
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| Brain Res 1305 Suppl:S72-9. Epub 2009 Aug 19.PMID: 19698703 2009
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| 3 | CHRNA6, CHRNB3
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| SNPs in CHRNA6 and CHRNB3 are associated with alcohol consumption in a nationally representative sample.
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| Hoft NR, Corley RP, McQueen MB, Huizinga D, Menard S, Ehringer MA.
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| Genes Brain Behav 8(6):631-7. Epub 2009 Mar 23.PMID: 19500157 2009
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| 4 | CHRNA6, CHRNB3
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| Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample.
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| Hoft NR, Corley RP, McQueen MB, Schlaepfer IR, Huizinga D, Ehringer MA.
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| Neuropsychopharmacology 34(3):698-706. Epub 2008 Aug 13.PMID: 18704094 2009
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| 5 | CHRNA3, CHRNA5, CHRNB3
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| A variant associated with nicotine dependence, lung cancer and peripheral arterial disease.
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| Thorgeirsson TE, Geller F, Sulem P, Rafnar T, Wiste A, Magnusson KP, Manolescu A, Thorleifsson G, Stefansson H, Ingason A, Stacey SN, Bergthorsson JT, Thorlacius S, Gudmundsson J, Jonsson T, Jakobsdottir M, Saemundsdottir J, Olafsdottir O, Gudmundsson LJ, Bjornsdottir G, Kristjansson K, Skuladottir H, Isaksson HJ, Gudbjartsson T, Jones GT, Mueller T, Gottsäter A, Flex A, Aben KK, de Vegt F, Mulders PF, Isla D, Vidal MJ, Asin L, Saez B, Murillo L, Blondal T, Kolbeinsson H, Stefansson JG, Hansdottir I, Runarsdottir V, Pola R, Lindblad B, van Rij AM, Dieplinger B, Haltmayer M, Mayordomo JI, Kiemeney LA, Matthiasson SE, Oskarsson H, Tyrfingsson T, Gudbjartsson DF, Gulcher JR, Jonsson S, Thorsteinsdottir U, Kong A, Stefansson K.
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| Nature 452(7187):638-42.
2008
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| 6 | CHRNA3, CHRNA5, CHRNB3
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| Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.
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| Amos CI, Wu X, Broderick P, Gorlov IP, Gu J, Eisen T, Dong Q, Zhang Q, Gu X, Vijayakrishnan J, Sullivan K, Matakidou A, Wang Y, Mills G, Doheny K, Tsai YY, Chen WV, Shete S, Spitz MR, Houlston RS.
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| Nat Genet 40(5):616-22. Epub 2008 Apr 2.
2008
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| 7 | CHRNA6, CHRNB3
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| The neuronal nicotinic receptor subunit genes (CHRNA6 and CHRNB3) are associated with subjective responses to tobacco.
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| Zeiger JS, Haberstick BC, Schlaepfer I, Collins AC, Corley RP, Crowley TJ, Hewitt JK, Hopfer CJ, Lessem J, McQueen MB, Rhee SH, Ehringer MA.
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| Hum Mol Genet 17(5):724-34. Epub 2007 Nov 30.PMID: 18055561 2008
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| 8 | CHRNA5, CHRNB3
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| Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs.
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| Saccone SF, Hinrichs AL, Saccone NL, Chase GA, Konvicka K, Madden PA, Breslau N, Johnson EO, Hatsukami D, Pomerleau O, Swan GE, Goate AM, Rutter J, Bertelsen S, Fox L, Fugman D, Martin NG, Montgomery GW, Wang JC, Ballinger DG, Rice JP, Bierut LJ.
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| Hum Mol Genet 16(1):36-49. Epub 2006 Nov 29. 2007
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| 9 | CHRNA2, CHRNA3, CHRNA4, CHRNA5, CHRNA6, CHRNA7, CHRNB2, CHRNB3, CHRNB4
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| Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.
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| Elliott KJ, Ellis SB, Berckhan KJ, Urrutia A, Chavez-Noriega LE, Johnson EC, Veliçelebi G, Harpold MM.
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| J Mol Neurosci 7(3):217-28.
1996
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| 10 | CHRNB3
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| Mapping of the human nicotinic acetylcholine receptor beta3 gene (CHRNB3) within chromosome 8p11.2.
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| Koyama K, et al.
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| Genomics 21 : 460-461. 1994
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| 11 | CHRN@, CHRNA4, CHRNB2, CHRNA2, CHRNB3
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| Chromosomal localization of seven neuronal nicotinic acetylcholine receptor subunit genes in humans.
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| Anand R, et al.
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| Genomics 13 : 962-967. 1992
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| 12 | CHRNA2, CHRNA4, CHRNA5, CHRNB2, CHRNB3, CHRNB4
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| Chromosomal localization of seven neuronal nicotinic acetylcholine receptor subunit genes in humans.
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| Anand R, Lindstrom J.
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| Genomics 13(4):962-7.
1992
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