| 1 | CHRNA3, CHRNA5
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| Four SNPs in the CHRNA3/5 alpha-neuronal nicotinic acetylcholine receptor subunit locus are associated with COPD risk based on meta-analyses.
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| Cui K, Ge X, Ma H.
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| PLoS One 9(7):e102324. doi: 10.1371/journal.pone.0102324. eCollection 2014.
2014
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| 2 | CHRNA3, CHRNA5, CHRNB4, VPS13A
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| Genetics of alcohol dependence.
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| Gelernter J, Kranzler HR.
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| Hum Genet 126(1):91-9. Epub 2009 Jun 17. Review.
2009
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| 3 | CHRNA3, CHRNA5, CHRNB4
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| A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.
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| Hung RJ, McKay JD, Gaborieau V, Boffetta P, Hashibe M, Zaridze D, Mukeria A, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, Chen C, Goodman G, Field JK, Liloglou T, Xinarianos G, Cassidy A, McLaughlin J, Liu G, Narod S, Krokan HE, Skorpen F, Elvestad MB, Hveem K, Vatten L, Linseisen J, Clavel-Chapelon F, Vineis P, Bueno-de-Mesquita HB, Lund E, Martinez C, Bingham S, Rasmuson T, Hainaut P, Riboli E, Ahrens W, Benhamou S, Lagiou P, Trichopoulos D, Holcátová I, Merletti F, Kjaerheim K, Agudo A, Macfarlane G, Talamini R, Simonato L, Lowry R, Conway DI, Znaor A, Healy C, Zelenika D, Boland A, Delepine M, Foglio M, Lechner D, Matsuda F, Blanche H, Gut I, Heath S, Lathrop M, Brennan P.
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| Nature 452(7187):633-7.
2008
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| 4 | CHRNA3, CHRNA5, CHRNB3
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| A variant associated with nicotine dependence, lung cancer and peripheral arterial disease.
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| Thorgeirsson TE, Geller F, Sulem P, Rafnar T, Wiste A, Magnusson KP, Manolescu A, Thorleifsson G, Stefansson H, Ingason A, Stacey SN, Bergthorsson JT, Thorlacius S, Gudmundsson J, Jonsson T, Jakobsdottir M, Saemundsdottir J, Olafsdottir O, Gudmundsson LJ, Bjornsdottir G, Kristjansson K, Skuladottir H, Isaksson HJ, Gudbjartsson T, Jones GT, Mueller T, Gottsäter A, Flex A, Aben KK, de Vegt F, Mulders PF, Isla D, Vidal MJ, Asin L, Saez B, Murillo L, Blondal T, Kolbeinsson H, Stefansson JG, Hansdottir I, Runarsdottir V, Pola R, Lindblad B, van Rij AM, Dieplinger B, Haltmayer M, Mayordomo JI, Kiemeney LA, Matthiasson SE, Oskarsson H, Tyrfingsson T, Gudbjartsson DF, Gulcher JR, Jonsson S, Thorsteinsdottir U, Kong A, Stefansson K.
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| Nature 452(7187):638-42.
2008
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| 5 | CHRNA5
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| A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.
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| Hung RJ, McKay JD, Gaborieau V, Boffetta P, Hashibe M, Zaridze D, Mukeria A, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, Chen C, Goodman G, Field JK, Liloglou T, Xinarianos G, Cassidy A, McLaughlin J, Liu G, Narod S, Krokan HE, Skorpen F, Elvestad MB, Hveem K, Vatten L, Linseisen J, Clavel-Chapelon F, Vineis P, Bueno-de-Mesquita HB, Lund E, Martinez C, Bingham S, Rasmuson T, Hainaut P, Riboli E, Ahrens W, Benhamou S, Lagiou P, Trichopoulos D, Holc‡tov‡ I, Merletti F, Kjaerheim K, Agudo A, Macfarlane G, Talamini R, Simonato L, Lowry R, Conway DI, Znaor A, Healy C, Zelenika D, Boland A, Delepine M, Foglio M, Lechner D, Matsuda F, Blanche H, Gut I, Heath S, Lathrop M, Brennan P.
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| Nature 452(7187):633-7. 2008
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| 6 | CHRNA3, CHRNA5, CHRNB3
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| Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.
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| Amos CI, Wu X, Broderick P, Gorlov IP, Gu J, Eisen T, Dong Q, Zhang Q, Gu X, Vijayakrishnan J, Sullivan K, Matakidou A, Wang Y, Mills G, Doheny K, Tsai YY, Chen WV, Shete S, Spitz MR, Houlston RS.
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| Nat Genet 40(5):616-22. Epub 2008 Apr 2.
2008
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| 7 | CHRNA3, CHRNA5, CHRNB4
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| Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans.
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| Joslyn G, Brush G, Robertson M, Smith TL, Kalmijn J, Schuckit M, White RL.
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| Proc Natl Acad Sci U S A 105(51):20368-73. Epub 2008 Dec 8.
2008
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| 8 | CHRNA5
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| The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer.
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| Spitz MR, Amos CI, Dong Q, Lin J, Wu X.
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| J Natl Cancer Inst 100(21):1552-6. Epub 2008 Oct 28.
2008
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| 9 | CHRNA5, CHRNB3
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| Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs.
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| Saccone SF, Hinrichs AL, Saccone NL, Chase GA, Konvicka K, Madden PA, Breslau N, Johnson EO, Hatsukami D, Pomerleau O, Swan GE, Goate AM, Rutter J, Bertelsen S, Fox L, Fugman D, Martin NG, Montgomery GW, Wang JC, Ballinger DG, Rice JP, Bierut LJ.
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| Hum Mol Genet 16(1):36-49. Epub 2006 Nov 29. 2007
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| 10 | CHRNA3, CHRNA5, CHRNB4
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| Characterization of the genomic structure of the human neuronal nicotinic acetylcholine receptor CHRNA5/A3/B4 gene cluster and identification of novel intragenic polymorphisms
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| Duga S, Solda G, Asselta R, Bonati MT, Dalpra L, Malcovati M, Tenchini ML.
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| J Hum Genet 46(11):640-8. 2001
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| 11 | CHRNA2, CHRNA3, CHRNA4, CHRNA5, CHRNA6, CHRNA7, CHRNB2, CHRNB3, CHRNB4
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| Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.
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| Elliott KJ, Ellis SB, Berckhan KJ, Urrutia A, Chavez-Noriega LE, Johnson EC, Veliçelebi G, Harpold MM.
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| J Mol Neurosci 7(3):217-28.
1996
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| 12 | CHRN@, CHRNA3, CHRNA5, CHRNB4
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| Chromosomal localization and physical linkage of the genes encoding the human alpha 3, alpha 5, and beta 4 neuronal nicotinic receptor subunits.
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| Raimondi E, et al.
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| Genomics 12 : 849-850. 1992
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| 13 | CHRNA2, CHRNA4, CHRNA5, CHRNB2, CHRNB3, CHRNB4
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| Chromosomal localization of seven neuronal nicotinic acetylcholine receptor subunit genes in humans.
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| Anand R, Lindstrom J.
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| Genomics 13(4):962-7.
1992
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