| 1 | CHN1, CNTNAP1
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| Novel Mutation in CNTNAP1 results in Congenital Hypomyelinating Neuropathy.
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| Mehta P, Küspert M, Bale T, Brownstein CA, Towne MC, De Girolami U, Shi J, Beggs AH, Darras BT, Wegner M, Piao X, Agrawal PB.
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| Muscle Nerve uscle Nerve. 2016 Sep 26. doi: 10.1002/mus.25416. [Epub ahead of print]
2016
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| 2 | CHN1
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| Developmental RacGAP α2-Chimaerin Signaling Is a Determinant of the Morphological Features of Dendritic Spines in Adulthood.
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| Iwata R, Matsukawa H, Yasuda K, Mizuno H, Itohara S, Iwasato T.
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| J Neurosci 35(40):13728-44. doi: 10.1523/JNEUROSCI.0419-15.2015.
2015
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| 3 | CHN1
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| α2-chimaerin is required for Eph receptor-class-specific spinal motor axon guidance and coordinate activation of antagonistic muscles.
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| Kao TJ, Nicholl GC, Johansen JA, Kania A, Beg AA.
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| J Neurosci 35(6):2344-57. doi: 10.1523/JNEUROSCI.4151-14.2015.
2015
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| 4 | CHN1
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| RacGAP α2-chimaerin function in development adjusts cognitive ability in adulthood.
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| Iwata R, Ohi K, Kobayashi Y, Masuda A, Iwama M, Yasuda Y, Yamamori H, Tanaka M, Hashimoto R, Itohara S, Iwasato T.
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| Cell Rep 8(5):1257-64. doi: 10.1016/j.celrep.2014.07.047.
2014
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| 5 | CHN1, DURS2
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| α2-Chimaerin regulates a key axon guidance transition during development of the oculomotor projection.
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| Clark C, Austen O, Poparic I, Guthrie S.
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| J Neurosci 33(42):16540-51. doi: 10.1523/JNEUROSCI.1869-13.2013.
2013
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| 6 | CHN1, DURS2, PLXNA1, PLXNA2
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| Axon guidance in the developing ocular motor system and Duane retraction syndrome depends on Semaphorin signaling via alpha2-chimaerin.
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| Ferrario JE, Baskaran P, Clark C, Hendry A, Lerner O, Hintze M, Allen J, Chilton JK, Guthrie S.
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| Proc Natl Acad Sci U S A 109(36):14669-74. doi: 10.1073/pnas.1116481109.
2012
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| 7 | CHN1, CHN2, SEMA3F
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| The RacGAP β2-Chimaerin selectively mediates axonal pruning in the hippocampus.
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| Riccomagno MM, Hurtado A, Wang H, Macopson JG, Griner EM, Betz A, Brose N, Kazanietz MG, Kolodkin AL.
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| Cell 149(7):1594-606. doi: 10.1016/j.cell.2012.05.018.
2012
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| 8 | CHN1, DPYSL2
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| α2-chimaerin controls neuronal migration and functioning of the cerebral cortex through CRMP-2.
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| Ip JP, Shi L, Chen Y, Itoh Y, Fu WY, Betz A, Yung WH, Gotoh Y, Fu AK, Ip NY.
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| Nat Neurosci 15(1):39-47. doi: 10.1038/nn.2972.
2011
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| 9 | CHN1, DURS2
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| Two novel CHN1 mutations in 2 families with Duane retraction syndrome.
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| Chan WM, Miyake N, Zhu-Tam L, Andrews C, Engle EC.
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| Arch Ophthalmol 129(5):649-52. doi: 10.1001/archophthalmol.2011.84.
2011
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| 10 | CHN1
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| Cortical control of adaptive locomotion in wild-type mice and mutant mice lacking the ephrin-Eph effector protein alpha2-chimaerin.
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| Asante CO, Chu A, Fisher M, Benson L, Beg A, Scheiffele P, Martin J.
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| J Neurophysiol 104(6):3189-202. doi: 10.1152/jn.00671.2010.
2010
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| 11 | CHN1, DURS2
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| Human CHN1 mutations hyperactivate alpha2-chimaerin and cause Duane's retraction syndrome.
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| Miyake N, Chilton J, Psatha M, Cheng L, Andrews C, Chan WM, Law K, Crosier M, Lindsay S, Cheung M, Allen J, Gutowski NJ, Ellard S, Young E, Iannaccone A, Appukuttan B, Stout JT, Christiansen S, Ciccarelli ML, Baldi A, Campioni M, Zenteno JC, Davenport D, Mariani LE, Sahin M, Guthrie S, Engle EC.
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| Science 321(5890):839-43. Epub 2008 Jul 24. 2008
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| 12 | CHN1, CHN2
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| Role of chimaerins, a group of Rac-specific GTPase activating proteins, in T-cell receptor signaling.
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| Caloca MJ, Delgado P, Alarcón B, Bustelo XR.
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| Cell Signal 20(4):758-70. Epub 2007 Dec 28. 2008
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| 13 | CDK5, CHN1
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| Alpha-chimaerin exists in a functional complex with the Cdk5 kinase in brain.
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| Qi RZ, Ching YP, Kung HF, Wang JH.
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| FEBS Lett 561(1-3):177-80.
2004
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| 14 | CHN1, CHN1P1
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| Alpha 2-chimerin, an SH2-containing GTPase-activating protein for the ras-related protein p21rac derived by alternate splicing of the human n-chimerin gene, is selectively expressed in brain regions and testes.
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| Hall C, et al.
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| Mol Cell Biol 13 : 4986-4998. 1993
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| 15 | CHN1, CHN2
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| Novel human brain cDNA encoding a 34,000 Mr protein n-chimaerin, related to both the regulatory domain of protein kinase C and BCR, the product of the breakpoint cluster region gene.
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| Hall C, et al.
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| J Mol Biol 211 : 11-16. 1990
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