Citations for
1CHKA, EGFR
Functional interactions between Choline kinase α, epidermal growth factor receptor and c-Src in breast cancer cell proliferation.
Miyake T, Parsons SJ.
Oncogene 31(11):1431-41. doi: 10.1038/onc.2011.332. Epub 2011 Aug 8. 2012
2CHKA, CHKB
Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity.
Hong BS, Allali-Hassani A, Tempel W, Finerty PJ Jr, Mackenzie F, Dimov S, Vedadi M, Park HW.
J Biol Chem 285(21):16330-40. Epub 2010 Mar 18. 2010
3CHKA, CHKB
Choline kinase and its function.
Wu G, Vance DE.
Biochem Cell Biol 88(4):559-64. Review. 2010
4CHKA, CHKB
Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatment.
Gallego-Ortega D, Ramirez de Molina A, Ramos MA, Valdes-Mora F, Barderas MG, Sarmentero-Estrada J, Lacal JC.
PLoS One 4(11):e7819. 2009
5CHKA, CHKB
Understanding the muscular dystrophy caused by deletion of choline kinase beta in mice.
Wu G, Sher RB, Cox GA, Vance DE.
Biochim Biophys Acta 1791(5):347-56. Erratum in: Biochim Biophys Acta. 2010 Feb;1801(2):205. 2009
6CHKA
Overexpression of choline kinase is a frequent feature in human tumor-derived cell lines and in lung, prostate, and colorectal human cancers.
Ramirez de Molina A, Rodriguez-Gonzalez A, Gutierrez R, Martinez-Pineiro L, Sanchez J, Bonilla F, Rosell R, Lacal J.
Biochem Biophys Res Commun 296(3):580-3. 2002
7CHKA
Increased choline kinase activity in human breast carcinomas: clinical evidence for a potential novel antitumor strategy.
Ramirez de Molina A, Gutierrez R, Ramos MA, Silva JM, Silva J, Bonilla F, Sanchez JJ, Lacal JC.
Oncogene 21(27):4317-22. 2002
8CHKA
Regulation of choline kinase activity by Ras proteins involves Ral-GDS and PI3K.
Ramirez de Molina A, Penalva V, Lucas L, Lacal JC.
Oncogene 21(6):937-46. 2002
9CHKA
Increased choline kinase activity and elevated phosphocholine levels in humancolon cancer.
Nakagami K, Uchida T, Ohwada S, Koibuchi Y, Suda Y, Sekine T, Morishita Y.
Jpn J Cancer Res 90(4):419-24. 1999
10CHKA
Cloning of a human choline kinase cDNA by complementation of the yeast ckimutation.
Hosaka K, Tanaka S, Nikawa J, Yamashita S.
FEBS Lett 304(2-3):229-32. 1992