1 | CHKA, EGFR
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| Functional interactions between Choline kinase α, epidermal growth factor receptor and c-Src in breast cancer cell proliferation.
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| Miyake T, Parsons SJ.
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| Oncogene 31(11):1431-41. doi: 10.1038/onc.2011.332. Epub 2011 Aug 8.
2012
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2 | CHKA, CHKB
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| Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity.
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| Hong BS, Allali-Hassani A, Tempel W, Finerty PJ Jr, Mackenzie F, Dimov S, Vedadi M, Park HW.
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| J Biol Chem 285(21):16330-40. Epub 2010 Mar 18.
2010
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3 | CHKA, CHKB
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| Choline kinase and its function.
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| Wu G, Vance DE.
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| Biochem Cell Biol 88(4):559-64. Review.
2010
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4 | CHKA, CHKB
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| Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatment.
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| Gallego-Ortega D, Ramirez de Molina A, Ramos MA, Valdes-Mora F, Barderas MG, Sarmentero-Estrada J, Lacal JC.
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| PLoS One 4(11):e7819.
2009
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5 | CHKA, CHKB
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| Understanding the muscular dystrophy caused by deletion of choline kinase beta in mice.
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| Wu G, Sher RB, Cox GA, Vance DE.
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| Biochim Biophys Acta 1791(5):347-56. Erratum in: Biochim Biophys Acta. 2010 Feb;1801(2):205.
2009
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6 | CHKA
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| Overexpression of choline kinase is a frequent feature in human tumor-derived cell lines and in lung, prostate, and colorectal human cancers.
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| Ramirez de Molina A, Rodriguez-Gonzalez A, Gutierrez R, Martinez-Pineiro L, Sanchez J, Bonilla F, Rosell R, Lacal J.
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| Biochem Biophys Res Commun 296(3):580-3. 2002
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7 | CHKA
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| Increased choline kinase activity in human breast carcinomas: clinical evidence for a potential novel antitumor strategy.
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| Ramirez de Molina A, Gutierrez R, Ramos MA, Silva JM, Silva J, Bonilla F, Sanchez JJ, Lacal JC.
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| Oncogene 21(27):4317-22. 2002
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8 | CHKA
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| Regulation of choline kinase activity by Ras proteins involves Ral-GDS and PI3K.
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| Ramirez de Molina A, Penalva V, Lucas L, Lacal JC.
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| Oncogene 21(6):937-46. 2002
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9 | CHKA
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| Increased choline kinase activity and elevated phosphocholine levels in humancolon cancer.
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| Nakagami K, Uchida T, Ohwada S, Koibuchi Y, Suda Y, Sekine T, Morishita Y.
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| Jpn J Cancer Res 90(4):419-24. 1999
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10 | CHKA
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| Cloning of a human choline kinase cDNA by complementation of the yeast ckimutation.
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| Hosaka K, Tanaka S, Nikawa J, Yamashita S.
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| FEBS Lett 304(2-3):229-32. 1992
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