Citations for
1CFL1, WDR1
Real-Time Single Molecule Kinetics Analyses of AIP1-Enhanced Actin Filament Severing in the Presence of Cofilin.
Hayakawa K, Sekiguchi C, Sokabe M, Ono S, Tatsumi H.
J Mol Biol Mol Biol. 2018 Nov 12. pii: S0022-2836(18)30523-0. doi: 10.1016/j.jmb.2018.11.010. [Epub ahead of print] 2018
2CFL1, WDR1
Wdr-1 is essential for F-actin interaction with focal adhesions in platelets.
Dasgupta SK, Thiagarajan P.
Blood Coagul Fibrinolysis 29(6):540-545. doi: 10.1097/MBC.0000000000000756. 2018
3CFL1, TESK1
Regulation of cofilin phosphorylation in glomerular podocytes by testis specific kinase 1 (TESK1).
Wang L, Buckley AF, Spurney RF.
Sci Rep 8(1):12286. doi: 10.1038/s41598-018-30115-3. 2018
4CFL1
Cofilin-1 levels and intracellular localization are associated with melanoma prognosis in a cohort of patients.
Bracalente C, Rinflerch AR, Ibañez IL, García FM, Volonteri V, Galimberti GN, Klamt F, Durán H.
Oncotarget 9(35):24097-24108. doi: 10.18632/oncotarget.25303. eCollection 2018 May 8. 2018
5CFL1, UGP2
Expression of UGP2 and CFL1 expression levels in benign and malignant pancreatic lesions and their clinicopathological significance.
Wang L, Xiong L, Wu Z, Miao X, Liu Z, Li D, Zou Q, Yang Z.
World J Surg Oncol 16(1):11. doi: 10.1186/s12957-018-1316-7. 2018
6CFL1, LIMK1, WDR1
Trp-Asp (WD) Repeat Domain 1 Is Essential for Mouse Peri-implantation Development and Regulates Cofilin Phosphorylation.
Xiao Y, Ma H, Wan P, Qin D, Wang X, Zhang X, Xiang Y, Liu W, Chen J, Yi Z, Li L.
J Biol Chem 292(4):1438-1448. doi: 10.1074/jbc.M116.759886. Epub 2016 Dec 19. 2017
7CFL1
A transient pool of nuclear F-actin at mitotic exit controls chromatin organization.
Baarlink C, Plessner M, Sherrard A, Morita K, Misu S, Virant D, Kleinschnitz EM, Harniman R, Alibhai D, Baumeister S, Miyamoto K, Endesfelder U, Kaidi A, Grosse R.
Nat Cell Biol 19(12):1389-1399. doi: 10.1038/ncb3641. Epub 2017 Nov 13. 2017
8CFL1, FRAXA, RAC1
Aberrant Rac1-cofilin signaling mediates defects in dendritic spines, synaptic function, and sensory perception in fragile X syndrome.
Pyronneau A, He Q, Hwang JY, Porch M, Contractor A, Zukin RS.
Sci Signal 10(504). pii: eaan0852. doi: 10.1126/scisignal.aan0852. 2017
9CAPZB, CFL1, DIAPH1
Actin cortex architecture regulates cell surface tension.
Chugh P, Clark AG, Smith MB, Cassani DAD, Dierkes K, Ragab A, Roux PP, Charras G, Salbreux G, Paluch EK.
Nat Cell Biol 19(6):689-697. doi: 10.1038/ncb3525. Epub 2017 May 22. 2017
10CFL1
Cofilin 1 induces the epithelial-mesenchymal transition of gastric cancer cells by promoting cytoskeletal rearrangement.
Wang H, Tao L, Jin F, Gu H, Dai X, Ni T, Feng J, Ding Y, Xiao W, Qian Y, Liu Y.
Oncotarget 8(24):39131-39142. doi: 10.18632/oncotarget.16608. 2017
11CFL1
Association of epithelial-mesenchymal transition and nuclear cofilin with advanced urothelial cancer.
Hensley PJ, Zetter D, Horbinski CM, Strup SE, Kyprianou N.
Hum Pathol 57:68-77. doi: 10.1016/j.humpath.2016.06.020. Epub 2016 Jul 8. 2016
12AURKA, CFL1
Aurora kinase A induces papillary thyroid cancer lymph node metastasis by promoting cofilin-1 activity.
Maimaiti Y, Jie T, Jing Z, Changwen W, Pan Y, Chen C, Tao H.
Biochem Biophys Res Commun 473(1):212-218. doi: 10.1016/j.bbrc.2016.03.081. Epub 2016 Mar 19. 2016
13CFL1
ADF and Cofilin1 Control Actin Stress Fibers, Nuclear Integrity, and Cell Survival.
Kanellos G, Zhou J, Patel H, Ridgway RA, Huels D, Gurniak CB, Sandilands E, Carragher NO, Sansom OJ, Witke W, Brunton VG, Frame MC.
Cell Rep 13(9):1949-64. doi: 10.1016/j.celrep.2015.10.056. Epub 2015 Nov 19. 2015
14CFL1
Inhibiting actin depolymerization enhances osteoblast differentiation and bone formation in human stromal stem cells.
Chen L, Shi K, Frary CE, Ditzel N, Hu H, Qiu W, Kassem M.
Stem Cell Res 15(2):281-9. doi: 10.1016/j.scr.2015.06.009. Epub 2015 Jun 30. 2015
15CFL1
Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains.
Grego-Bessa J, Hildebrand J, Anderson KV.
Development 142(7):1305-14. doi: 10.1242/dev.115493. Epub 2015 Mar 5. 2015
16ATP2C1, CFL1
Cofilin recruits F-actin to SPCA1 and promotes Ca2+-mediated secretory cargo sorting.
Kienzle C, Basnet N, Crevenna AH, Beck G, Habermann B, Mizuno N, von Blume J.
J Cell Biol 206(5):635-54. doi: 10.1083/jcb.201311052. 2014
17CFL1
Cofilin/actin rod formation by dysregulation of cofilin-1 activity as a central initial step in neurodegeneration.
Schönhofen P, de Medeiros LM, Chatain CP, Bristot IJ, Klamt F.
Mini Rev Med Chem 14(5):393-400. Review. 2014
18CFL1
EWS represses cofilin 1 expression by inducing nuclear retention of cofilin 1 mRNA.
Huang L, Kuwahara I, Matsumoto K.
Oncogene 33(23):2995-3003. doi: 10.1038/onc.2013.255. Epub 2013 Jul 8. 2014
19CFL1, IRS4, SSH1
Insulin receptor substrate-4 binds to Slingshot-1 phosphatase and promotes cofilin dephosphorylation.
Homma Y, Kanno S, Sasaki K, Nishita M, Yasui A, Asano T, Ohashi K, Mizuno K.
J Biol Chem. Sep 19;289(38):26302-13. doi: 10.1074/jbc.M114.565945. Epub 2014 Aug 6 2014
20CFL1
Non-overlapping activities of ADF and cofilin-1 during the migration of metastatic breast tumor cells.
Tahtamouni LH, Shaw AE, Hasan MH, Yasin SR, Bamburg JR.
BMC Cell Biol 14:45. doi: 10.1186/1471-2121-14-45. 2013
21CFL1, VANGL2
Cofilin and Vangl2 cooperate in the initiation of planar cell polarity in the mouse embryo.
Mahaffey JP, Grego-Bessa J, Liem KF Jr, Anderson KV.
Development 140(6):1262-71. doi: 10.1242/dev.085316. Epub 2013 Feb 13. 2013
22CFL1, WDR1
AIP1 acts with cofilin to control actin dynamics during epithelial morphogenesis.
Chu D, Pan H, Wan P, Wu J, Luo J, Zhu H, Chen J.
Development 139(19):3561-71. doi: 10.1242/dev.079491. Epub 2012 Aug 16. 2012
23CFL1
Cofilin aggregation blocks intracellular trafficking and induces synaptic loss in hippocampal neurons.
Cichon J, Sun C, Chen B, Jiang M, Chen XA, Sun Y, Wang Y, Chen G.
J Biol Chem 287(6):3919-29. doi: 10.1074/jbc.M111.301911. Epub 2011 Dec 19. 2012
24CAMK2D, CFL1, PPP3CA, SSH1
Regulation of cofilin activity by CaMKII and calcineurin.
Zhao JW, Gao ZL, Ji QY, Wang H, Zhang HY, Yang YD, Xing FJ, Meng LJ, Wang Y.
Am J Med Sci 344(6):462-72. doi: 10.1097/MAJ.0b013e318244745b. 2012
25CFL1, FAS
The death receptor CD95 activates the cofilin pathway to stimulate tumour cell invasion.
Steller EJ, Ritsma L, Raats DA, Hoogwater FJ, Emmink BL, Govaert KM, Laoukili J, Rinkes IH, van Rheenen J, Kranenburg O.
EMBO Rep 12(9):931-7. doi: 10.1038/embor.2011.129. 2011
26CFL1, FSCN1
Cofilin cooperates with fascin to disassemble filopodial actin filaments.
Breitsprecher D, Koestler SA, Chizhov I, Nemethova M, Mueller J, Goode BL, Small JV, Rottner K, Faix J.
J Cell Sci 124(Pt 19):3305-18. doi: 10.1242/jcs.086934. 2011
27CFL1, LIMK1
LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes.
Ishaq M, Lin BR, Bosche M, Zheng X, Yang J, Huang D, Lempicki RA, Natarajan V.
BMC Mol Biol 12:41. doi: 10.1186/1471-2199-12-41. 2011
28CFL1, LIMK1
LIM kinase mediates estrogen action on the actin depolymerization factor Cofilin.
Yuen GS, McEwen BS, Akama KT.
Brain Res 1379:44-52. doi: 10.1016/j.brainres.2010.07.067. Epub 2010 Aug 7. 2011
29CFL1
Remodeling of actin filaments by ADF/cofilin proteins.
Galkin VE, Orlova A, Kudryashov DS, Solodukhin A, Reisler E, Schröder GF, Egelman EH.
Proc Natl Acad Sci U S A 108(51):20568-72. doi: 10.1073/pnas.1110109108. Epub 2011 Dec 7. 2011
30CFL1
Tyrosine phosphorylation of cofilin at Y68 by v-Src leads to its degradation through ubiquitin-proteasome pathway.
Yoo Y, Ho HJ, Wang C, Guan JL.
Oncogene 29(2):263-72. Epub 2009 Oct 5.PMID: 19802004 2010
31CFL1, HUNK, PPP2R4
HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1.
Quintela-Fandino M, Arpaia E, Brenner D, Goh T, Yeung FA, Blaser H, Alexandrova R, Lind EF, Tusche MW, Wakeham A, Ohashi PS, Mak TW.
Proc Natl Acad Sci U S A 107(6):2622-7. Epub 2010 Jan 22.PMID: 20133759 2010
32CFL1
ADF/cofilin-mediated actin dynamics regulate AMPA receptor trafficking during synaptic plasticity.
Gu J, Lee CW, Fan Y, Komlos D, Tang X, Sun C, Yu K, Hartzell HC, Chen G, Bamburg JR, Zheng JQ.
Nat Neurosci. 13(10):1208-15. 2010
33CFL1, CORO2A
Coronin 2A regulates a subset of focal-adhesion-turnover events through the cofilin pathway.
Marshall TW, Aloor HL, Bear JE.
J Cell Sci 122(Pt 17):3061-9. Epub 2009 Aug 4.PMID: 19654210 [ 2009
34CDKN1B, CFL1
Regulated expression of cofilin and the consequent regulation of p27(kip1) are essential for G(1) phase progression.
Tsai CH, Chiu SJ, Liu CC, Sheu TJ, Hsieh CH, Keng PC, Lee YJ.
Cell Cycle 8(15):2365-74. Epub 2009 Aug 20.PMID: 19556892 2009
35CFL1
Essential role of cofilin-1 in regulating thrombin-induced RelA/p65 nuclear translocation and intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells.
Fazal F, Bijli KM, Minhajuddin M, Rein T, Finkelstein JN, Rahman A.
J Biol Chem 284(31):21047-56. Epub 2009 May 29.PMID: 19483084 2009
36CFL1
Decreased cofilin1 expression is important for compaction during early mouse embryo development.
Ma M, Zhou L, Guo X, Lv Z, Yu Y, Ding C, Zhang P, Bi Y, Xie J, Wang L, Lin M, Zhou Z, Huo R, Sha J, Zhou Q.
Biochim Biophys Acta 1793(12):1804-10. Epub 2009 Sep 12.PMID: 19751773 2009
37CFL1, ERBB2, MEMO1, PLCG1
Memo is a cofilin-interacting protein that influences PLCgamma1 and cofilin activities, and is essential for maintaining directionality during ErbB2-induced tumor-cell migration.
Meira M, Masson R, Stagljar I, Lienhard S, Maurer F, Boulay A, Hynes NE.
J Cell Sci 122(Pt 6):787-97. Epub 2009 Feb 17. 2009
38CFL1
Cofilin mediates tight-junction opening by redistributing actin and tight-junction proteins.
Nagumo Y, Han J, Bellila A, Isoda H, Tanaka T.
Biochem Biophys Res Commun 377(3):921-5. Epub 2008 Oct 24.PMID: 18952063 2008
39CFL1, PDXP
Chronophin mediates an ATP-sensing mechanism for cofilin dephosphorylation and neuronal cofilin-actin rod formation.
Huang TY, Minamide LS, Bamburg JR, Bokoch GM.
Dev Cell 15(5):691-703. doi: 10.1016/j.devcel.2008.09.017. 2008
40CFL1, LIMK1, PRKN
Parkin interacts with LIM Kinase 1 and reduces its cofilin-phosphorylation activity via ubiquitination.
Lim MK, Kawamura T, Ohsawa Y, Ohtsubo M, Asakawa S, Takayanagi A, Shimizu N.
Exp Cell Res 313(13):2858-74. Epub 2007 Apr 20.PMID: 17512523 2007
41CFL1
N-cofilin is associated with neuronal migration disorders and cell cycle control in the cerebral cortex.
Bellenchi GC, Gurniak CB, Perlas E, Middei S, Ammassari-Teule M, Witke W.
Genes Dev. 21(18):2347-57. 2007
42CFL1, CFL2, CFL3
Cofilin peptide homologs interfere with immunological synapse formation and T cell activation.
Eibert SM, Lee KH, Pipkorn R, Sester U, Wabnitz GH, Giese T, Meuer SC, Samstag Y.
Proc Natl Acad Sci U S A 101(7):1957-62. Epub 2004 Feb 03. 2004
43CFL1, CFL2, CFL3
Solution structure of human cofilin: actin binding, pH sensitivity, and relationship to actin-depolymerizing factor.
Pope BJ, Zierler-Gould KM, Kuhne R, Weeds AG, Ball LJ.
J Biol Chem 279(6):4840-8. Epub 2003 Nov 18. 2004
44BDNF, CFL1
Brain-derived neurotrophic factor regulation of retinal growth cone filopodial dynamics is mediated through actin depolymerizing factor/cofilin.
Gehler S, Shaw AE, Sarmiere PD, Bamburg JR, Letourneau PC.
J Neurosci 24(47):10741-9. 2004
45CFL1, UBA1
Screening of Hsp105alpha-binding proteins using yeast and bacterial two-hybrid systems.
Saito Y, Doi K, Yamagishi N, Ishihara K, Hatayama T.
Biochem Biophys Res Commun. 314(2):396-402. 2004
46CFL1
Control of growth cone motility and morphology by LIM kinase and Slingshot via phosphorylation and dephosphorylation of cofilin.
Endo M, Ohashi K, Sasaki Y, Goshima Y, Niwa R, Uemura T, Mizuno K.
J Neurosci 23(7):2527-37.PMID: 12684437 2003
47CFL1
Cofilin interacts with ClC-5 and regulates albumin uptake in proximal tubule cell lines.
Hryciw DH, Wang Y, Devuyst O, Pollock CA, Poronnik P, Guggino WB.
J Biol Chem. ;278(41):40169-76. 2003
48CFL1
Identification of cofilin and LIM-domain-containing protein kinase 1 as novel interaction partners of 14-3-3 zeta.
Birkenfeld J, Betz H, Roth D.
Biochem J. 369(Pt 1):45-54. 2003
49CAP1, CFL1
Human CAP1 is a key factor in the recycling of cofilin and actin for rapid actin turnover.
Moriyama K, Yahara I.
J Cell Sci 115(Pt 8):1591-601. 2002
50CFL1
Interaction of cofilin with triose-phosphate isomerase contributes glycolytic fuel for Na,K-ATPase via Rho-mediated signaling pathway.
Jung J, Yoon T, Choi EC, Lee K.
J Biol Chem. 277(50):48931-7. 2002
51CFL1
Structural conservation between the actin monomer-binding sites of twinfilin and actin-depolymerizing factor (ADF)/cofilin.
Paavilainen VO, Merckel MC, Falck S, Ojala PJ, Pohl E, Wilmanns M, Lappalainen P.
J Biol Chem. 277(45):43089-95. 2002
52CFL1
Interaction of the alpha subunit of Na,K-ATPase with cofilin.
Lee K, Jung J, Kim M, Guidotti G.
Biochem J. 353(Pt 2):377-85. 2001
53CFL1, GSN
Gelsolin and ADF/cofilin enhance the actin dynamics of motile cells.
Southwick FS.
Proc Natl Acad Sci U S A 97(13):6936-8. No abstract available. 2000
54CFL1
Aip1p interacts with cofilin to disassemble actin filaments.
Rodal AA, Tetreault JW, Lappalainen P, Drubin DG, Amberg DC.
J Cell Biol. 145(6):1251-64. 1999
55CFL1, LIMK1
Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization.
Yang N, et al.
Nature 393 : 809-812. 1998
56CFL1, CFL2, CFL3
Mapping of human non-muscle type cofilin (CFL1) to chromosome 11q13 and muscle-type cofilin (CFL2) to chromosome 14.
Gillett GT, et al.
Ann Hum Genet 60 : 201-211. 1996
57CFL1, CFL3
Coding sequence of human placenta Cofilin cDNA.
Ogawa K, et al.
Nucleic Acids Res 18 : 7169. 1990
58CFL1, TESK1
16.
Decreased TESK1-mediated cofilin 1 phosphorylation in the jejunum of IBS-D patients may explain increased female predisposition to epithelial dysfunction.
Rodiño-Janeiro BK, Martínez C, Fortea M, Lobo B, Pigrau M, Nieto A, González-Castro AM, Salvo-Romero E, Guagnozzi D, Pardo-Camac odiño-Janeiro BK, Martínez C, Fortea M, Lobo B, Pigrau M, Nieto A, González-Castro AM, Salvo-Romero E, Guagnozzi D, Pardo-Camach