Citations for
1CFH, CFHR3
Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations
Kumar V, Pouw RB, Autio MI, Sagmeister MG, Phua ZY, Borghini L, Wright VJ, Hoggart C, Pan B, Tan AKY, Binder A, Brouwer MC, Pinnock E, De Groot R, Hazelzet J, Emonts M, Van Der Flier M, Reiter K, Nöthen MM, Hoffmann P; EUCLIDS consortium, Schlapbach LJ, Bellos E, Anderson S, Secka F, Martinón-Torres F, Salas A, Fink C, Carrol ED, Pollard AJ, Coin LJ, Zenz W, Wouters D, Ang LT, Hibberd ML, Levin M, Kuijpers TW, Davila S.
Am J Hum Genet. Sep 1;109(9):1680-1691. doi: 10.1016/j.ajhg.2022.08.001. Epub 2022 Aug 24. 2022
2ARMD4, CFH, CFHR1, CFHR2, CFHR3, CFHR4
Beyond factor H: The impact of genetic-risk variants for age-related macular degeneration on circulating factor-H-like 1 and factor-H-related protein concentrations
Cipriani V, Tierney A, Griffiths JR, Zuber V, Sergouniotis PI, Yates JRW, Moore AT, Bishop PN, Clark SJ, Unwin RD.
Am J Hum Genet. Aug 5;108(8):1385-1400. doi: 10.1016/j.ajhg.2021.05.015. Epub 2021 Jul 13 2021
3CFHR3
CFHR3 is a potential novel biomarker for hepatocellular carcinoma
Liu J, Li W, Zhao H.
J Cell Biochem. Apr;121(4):2970-2980. doi: 10.1002/jcb.29551. Epub 2019 Nov 10 2020
4CFHR3
Complement factor H‑related 3 overexpression affects hepatocellular carcinoma proliferation and apoptosis.
Liu H, Zhang L, Wang P
Mol Med Rep. Sep;20(3):2694-2702. doi: 10.3892/mmr.2019.10514. Epub 2019 Jul 23. 2019
5CFHR3
FHR3 Blocks C3d-Mediated Coactivation of Human B Cells
Buhlmann D, Eberhardt HU, Medyukhina A, Prodinger WM, Figge MT, Zipfel PF, Skerka C.
J Immunol. Jul 15;197(2):620-9. doi: 10.4049/jimmunol.1600053. Epub 2016 Jun 8. 2016
6CFHR1, CFHR3
Variants in Complement Factor H and Complement Factor H-Related Protein Genes, CFHR3 and CFHR1, Affect Complement Activation in IgA Nephropathy..
Zhu L, Zhai YL, Wang FM, Hou P, Lv JC, Xu DM, Shi SF, Liu LJ, Yu F, Zhao MH, Novak J, Gharavi AG, Zhang H.
J Am Soc Nephrol May;26(5):1195-204. doi: 10.1681/ASN.2014010096. Epub 2014 Sep 9. 2015
7CFH, CFHR1, CFHR3
Complement factor H, FHR-3 and FHR-1 variants associate in an extended haplotype conferring increased risk of atypical hemolytic uremic syndrome.. 2015 PMID:
Bernabéu-Herrero ME, Jiménez-Alcázar M, Anter J, Pinto S, Sánchez Chinchilla D, Garrido S, López-Trascasa M, Rodríguez de Córdoba S, Sánchez-Corral P
Mol Immunol. Oct;67(2 Pt B):276-86. doi: 10.1016/j.molimm.2015.06.021. Epub 2015 Jul 7. 2015
8CFHR1, CFHR2, CFHR3, CFHR4, CFHR5
Complement factor H related proteins (CFHRs). 201. PMID:
Skerka C, Chen Q, Fremeaux-Bacchi V, Roumenina LT.
Mol Immunol. 3 Dec 15;56(3):170-80. doi: 10.1016/j.molimm.2013.06.001. Epub 2013 Jul 3 2013
9CFHR1, CFHR3
Factor H-related protein 1 neutralizes anti-factor H autoantibodies in autoimmune hemolytic uremic syndrome.
Strobel S, Abarrategui-Garrido C, Fariza-Requejo E, Seeberger H, Sánchez-Corral P, Józsi M.
Kidney Int idney Int. 2011 Jun 15. doi: 10.1038/ki.2011.152. [Epub ahead of print] 2011
10CFHR1, CFHR3, CROCC, RTT
Investigation of modifier genes within copy number variations in Rett syndrome.
Artuso R, Papa FT, Grillo E, Mucciolo M, Yasui DH, Dunaway KW, Disciglio V, Mencarelli MA, Pollazzon M, Zappella M, Hayek G, Mari F, Renieri A, Lasalle JM, Ariani F.
J Hum Genet Hum Genet. 2011 May 19. [Epub ahead of print] 2011
11CFH, CFHR3
Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease.
Davila S, Wright VJ, Khor CC, Sim KS, Binder A, Breunis WB, Inwald D, Nadel S, Betts H, Carrol ED, de Groot R, Hermans PW, Hazelzet J, Emonts M, Lim CC, Kuijpers TW, Martinon-Torres F, Salas A, Zenz W, Levin M, Hibberd ML; International Meningococcal Genetics Consortium.
Nat Genet 42(9):772-6. Epub 2010 Aug 8. 2010
12CFHR1, CFHR3
An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD).
Fritsche LG, Lauer N, Hartmann A, Stippa S, Keilhauer CN, Oppermann M, Pandey MK, Köhl J, Zipfel PF, Weber BH, Skerka C.
Hum Mol Genet 19(23):4694-704. Epub 2010 Sep 15. 2010
13CFHR3
Complement factor h autoantibodies and age-related macular degeneration.
Dhillon B, Wright AF, Tufail A, Pappworth I, Hayward C, Moore I, Strain L, Kavanagh D, Barlow PN, Herbert AP, Schmidt CQ, Armbrecht AM, Laude A, Deary IJ, Staniforth SJ, Holmes LV, Goodship TH, Marchbank KJ.
Invest Ophthalmol Vis Sci 51(11):5858-63. Epub 2010 Jun 30. 2010
14CFHR1, CFHR3, CFHR4
Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome.
Moore I, Strain L, Pappworth I, Kavanagh D, Barlow PN, Herbert AP, Schmidt CQ, Staniforth SJ, Holmes LV, Ward R, Morgan L, Goodship TH, Marchbank KJ.
Blood 115(2):379-87. Epub 2009 Oct 27. 2010
15CFHR1, CFHR3
Atypical hemolytic uremic syndrome associated with complement factor H autoantibodies and CFHR1/CFHR3 deficiency.
Lee BH, Kwak SH, Shin JI, Lee SH, Choi HJ, Kang HG, Ha IS, Lee JS, Dragon-Durey MA, Choi Y, Cheong HI.
Pediatr Res 66(3):336-40. 2009
16CFHR3
Contribution of copy number variation in the regulation of complement activation locus to development of age-related macular degeneration.
Schmid-Kubista KE, Tosakulwong N, Wu Y, Ryu E, Hecker LA, Baratz KH, Brown WL, Edwards AO.
Invest Ophthalmol Vis Sci 50(11):5070-9. Epub 2009 Jun 24. 2009
17CFHR1, CFHR3
Deletion of CFHR3 and CFHR1 genes in age-related macular degeneration.
Spencer KL, Hauser MA, Olson LM, Schmidt S, Scott WK, Gallins P, Agarwal A, Postel EA, Pericak-Vance MA, Haines JL.
Hum Mol Genet 17(7):971-7. Epub 2007 Dec 15. 2008
18CFHR1, CFHR3
A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degeneration.
Hughes AE, Orr N, Esfandiary H, Diaz-Torres M, Goodship T, Chakravarthy U.
Nat Genet 38(10):1173-7. Epub 2006 Sep 24. 2006
19CFHR4, CR1, CR2, CR1L, CFHR1, CFHR2, CFHR3, CFHR5
FHR-4A: a new factor H-related protein is encoded by the human FHR-4 gene.
Jozsi M, Richter H, Loschmann I, Skerka C, Buck F, Beisiegel U, Erdei A, Zipfel PF.
Eur J Hum Genet 13(3):321-9. 2005
20CFHR3, CFHR4
A radiation hybrid map of complement factor H and factor H-related genes.
Diaz-Guillen MA, Rodriguez de Cordoba S, Heine-Suner D.
Immunogenetics 49(6):549-52. No abstract available. 1999
21CFHR3
A novel short consensus repeat-containing molecule is related to human complement factor H.
Skerka C, Kuhn S, Gunther K, Lingelbach K, Zipfel PF.
J Biol Chem 268(4):2904-8. 1993