Citations for
1CEP250, CEP68, CNTLN
Centlein, a novel microtubule-associated protein stabilizing microtubules and involved in neurite formation.
Jing Z, Yin H, Wang P, Gao J, Yuan L.
Biochem Biophys Res Commun 472(2):360-5. doi: 10.1016/j.bbrc.2016.02.079. Epub 2016 Feb 23. 2016
2CEP135, CEP250
Multisite phosphorylation of C-Nap1 releases it from Cep135 to trigger centrosome disjunction.
Hardy T, Lee M, Hames RS, Prosser SL, Cheary DM, Samant MD, Schultz F, Baxter JE, Rhee K, Fry AM.
J Cell Sci 127(Pt 11):2493-506. doi: 10.1242/jcs.142331. Epub 2014 Apr 2. 2014
3CEP250, SCYL1
TEIF associated centrosome activity is regulated by EGF/PI3K/Akt signaling.
Zhao J, Zou Y, Liu H, Wang H, Zhang H, Hou W, Li X, Jia X, Zhang J, Hou L, Zhang B.
Biochim Biophys Acta 1843(9):1851-64. doi: 10.1016/j.bbamcr.2014.04.021. Epub 2014 Apr 25. 2014
4CEP250, CEP68, CNTLN
Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion.
Fang G, Zhang D, Yin H, Zheng L, Bi X, Yuan L.
J Cell Sci 127(Pt 8):1631-9. doi: 10.1242/jcs.139451. Epub 2014 Feb 19. 2014
5CEP250, CROCC
Multisite phosphorylation of C-Nap1 releases it from Cep135 to trigger centrosome disjunction.
Hardy T, Lee M, Hames RS, Prosser SL, Cheary DM, Samant MD, Schultz F, Baxter JE, Rhee K, Fry AM.
J Cell Sci 127(Pt 11):2493-506. doi: 10.1242/jcs.142331. Epub 2014 Apr 2. 2014
6CEP250, CROCC, LRRC45, NEK2
LRRC45 is a centrosome linker component required for centrosome cohesion.
He R, Huang N, Bao Y, Zhou H, Teng J, Chen J.
Cell Rep 4(6):1100-7. doi: 10.1016/j.celrep.2013.08.005. Epub 2013 Sep 12. 2013
7CEP135, CEP250, DCTN2, MCPH8
A Truncating Mutation of CEP135 Causes Primary Microcephaly and Disturbed Centrosomal Function.
Hussain MS, Baig SM, Neumann S, Nürnberg G, Farooq M, Ahmad I, Alef T, Hennies HC, Technau M, Altmüller J, Frommolt P, Thiele H, Noegel AA, Nürnberg P.
Am J Hum Genet 90(5):871-8. Epub 2012 Apr 19. 2012
8CEP250, NEK2
Nek2 localises to the distal portion of the mother centriole/basal body and is required for timely cilium disassembly at the G2/M transition.
Spalluto C, Wilson DI, Hearn T.
Eur J Cell Biol 91(9):675-86. doi: 10.1016/j.ejcb.2012.03.009. Epub 2012 May 19. 2012
9CEP250, CROCC
C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis.
Conroy PC, Saladino C, Dantas TJ, Lalor P, Dockery P, Morrison CG.
Cell Cycle 11(20):3769-78. doi: 10.4161/cc.21986. 2012
10CDK1, CEP250, KIF11
Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1.
Smith E, Hégarat N, Vesely C, Roseboom I, Larch C, Streicher H, Straatman K, Flynn H, Skehel M, Hirota T, Kuriyama R, Hochegger H.
EMBO J 30(11):2233-45. Epub 2011 Apr 26. 2011
11AXIN2, CEP250, CTNNB1
Conductin/axin2 and Wnt signalling regulates centrosome cohesion.
Hadjihannas MV, Brückner M, Behrens J.
EMBO Rep 11(4):317-24. Epub 2010 Mar 19.PMID: 20300119 2010
12CEP250, SIK2
SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer.
Ahmed AA, Lu Z, Jennings NB, Etemadmoghadam D, Capalbo L, Jacamo RO, Barbosa-Morais N, Le XF; Australian Ovarian Cancer Study Group, Vivas-Mejia P, Lopez-Berestein G, Grandjean G, Bartholomeusz G, Liao W, Andreeff M, Bowtell D, Glover DM, Sood AK, Bast RC Jr.
Cancer Cell 18(2):109-21. doi: 10.1016/j.ccr.2010.06.018. 2010
13CEP250, CROCC, NEK2
beta-Catenin is a Nek2 substrate involved in centrosome separation.
Bahmanyar S, Kaplan DD, Deluca JG, Giddings TH Jr, O'Toole ET, Winey M, Salmon ED, Casey PJ, Nelson WJ, Barth AI.
Genes Dev 22(1):91-105. Epub 2007 Dec 17.PMID: 18086858 2008
14CEP135, CEP250
A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization.
Kim K, Lee S, Chang J, Rhee K.
Exp Cell Res 314(20):3692-700. Epub 2008 Oct 1. 2008
15CDK5RAP2, CEP250, CEP68, CROCC
Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion.
Graser S, Stierhof YD, Nigg EA.
J Cell Sci 120(Pt 24):4321-31. Epub 2007 Nov 27.PMID: 18042621 2007
16CEP250, CROCC
Rootletin interacts with C-Nap1 and may function as a physical linker between the pair of centrioles/basal bodies in cells.
Yang J, Adamian M, Li T.
Mol Biol Cell 17(2):1033-40. Epub 2005 Dec 7.PMID: 16339073 2006
17CEP250, CROCC
Rootletin forms centriole-associated filaments and functions in centrosome cohesion.
Bahe S, Stierhof YD, Wilkinson CJ, Leiss F, Nigg EA.
J Cell Biol 171(1):27-33. Epub 2005 Oct 3.PMID: 16203858 2005
18CEP250
The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles.
Mayor T, Hacker U, Stierhof YD, Nigg EA.
J Cell Sci 115(Pt 16):3275-84. 2002
19CEP250
C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2.
Fry AM, Mayor T, Meraldi P, Stierhof YD, Tanaka K, Nigg EA.
J Cell Biol 141(7):1563-74. 1998
20CEP250
Autoantibodies to a group of centrosomal proteins in human autoimmune sera reactive with the centrosome.
Mack GJ, Rees J, Sandblom O, Balczon R, Fritzler MJ, Rattner JB.
Arthritis Rheum 41(3):551-8. 1998