1 | CEP250, CEP68, CNTLN
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| Centlein, a novel microtubule-associated protein stabilizing microtubules and involved in neurite formation.
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| Jing Z, Yin H, Wang P, Gao J, Yuan L.
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| Biochem Biophys Res Commun 472(2):360-5. doi: 10.1016/j.bbrc.2016.02.079. Epub 2016 Feb 23.
2016
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2 | CEP135, CEP250
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| Multisite phosphorylation of C-Nap1 releases it from Cep135 to trigger centrosome disjunction.
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| Hardy T, Lee M, Hames RS, Prosser SL, Cheary DM, Samant MD, Schultz F, Baxter JE, Rhee K, Fry AM.
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| J Cell Sci 127(Pt 11):2493-506. doi: 10.1242/jcs.142331. Epub 2014 Apr 2.
2014
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3 | CEP250, SCYL1
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| TEIF associated centrosome activity is regulated by EGF/PI3K/Akt signaling.
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| Zhao J, Zou Y, Liu H, Wang H, Zhang H, Hou W, Li X, Jia X, Zhang J, Hou L, Zhang B.
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| Biochim Biophys Acta 1843(9):1851-64. doi: 10.1016/j.bbamcr.2014.04.021. Epub 2014 Apr 25.
2014
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4 | CEP250, CEP68, CNTLN
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| Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion.
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| Fang G, Zhang D, Yin H, Zheng L, Bi X, Yuan L.
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| J Cell Sci 127(Pt 8):1631-9. doi: 10.1242/jcs.139451. Epub 2014 Feb 19.
2014
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5 | CEP250, CROCC
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| Multisite phosphorylation of C-Nap1 releases it from Cep135 to trigger centrosome disjunction.
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| Hardy T, Lee M, Hames RS, Prosser SL, Cheary DM, Samant MD, Schultz F, Baxter JE, Rhee K, Fry AM.
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| J Cell Sci 127(Pt 11):2493-506. doi: 10.1242/jcs.142331. Epub 2014 Apr 2.
2014
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6 | CEP250, CROCC, LRRC45, NEK2
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| LRRC45 is a centrosome linker component required for centrosome cohesion.
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| He R, Huang N, Bao Y, Zhou H, Teng J, Chen J.
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| Cell Rep 4(6):1100-7. doi: 10.1016/j.celrep.2013.08.005. Epub 2013 Sep 12.
2013
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7 | CEP135, CEP250, DCTN2, MCPH8
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| A Truncating Mutation of CEP135 Causes Primary Microcephaly and Disturbed Centrosomal Function.
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| Hussain MS, Baig SM, Neumann S, Nürnberg G, Farooq M, Ahmad I, Alef T, Hennies HC, Technau M, Altmüller J, Frommolt P, Thiele H, Noegel AA, Nürnberg P.
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| Am J Hum Genet 90(5):871-8. Epub 2012 Apr 19. 2012
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8 | CEP250, NEK2
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| Nek2 localises to the distal portion of the mother centriole/basal body and is required for timely cilium disassembly at the G2/M transition.
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| Spalluto C, Wilson DI, Hearn T.
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| Eur J Cell Biol 91(9):675-86. doi: 10.1016/j.ejcb.2012.03.009. Epub 2012 May 19.
2012
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9 | CEP250, CROCC
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| C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis.
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| Conroy PC, Saladino C, Dantas TJ, Lalor P, Dockery P, Morrison CG.
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| Cell Cycle 11(20):3769-78. doi: 10.4161/cc.21986.
2012
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10 | CDK1, CEP250, KIF11
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| Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1.
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| Smith E, Hégarat N, Vesely C, Roseboom I, Larch C, Streicher H, Straatman K, Flynn H, Skehel M, Hirota T, Kuriyama R, Hochegger H.
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| EMBO J 30(11):2233-45. Epub 2011 Apr 26.
2011
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11 | AXIN2, CEP250, CTNNB1
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| Conductin/axin2 and Wnt signalling regulates centrosome cohesion.
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| Hadjihannas MV, Brückner M, Behrens J.
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| EMBO Rep 11(4):317-24. Epub 2010 Mar 19.PMID: 20300119 2010
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12 | CEP250, SIK2
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| SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer.
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| Ahmed AA, Lu Z, Jennings NB, Etemadmoghadam D, Capalbo L, Jacamo RO, Barbosa-Morais N, Le XF; Australian Ovarian Cancer Study Group, Vivas-Mejia P, Lopez-Berestein G, Grandjean G, Bartholomeusz G, Liao W, Andreeff M, Bowtell D, Glover DM, Sood AK, Bast RC Jr.
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| Cancer Cell 18(2):109-21. doi: 10.1016/j.ccr.2010.06.018.
2010
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13 | CEP250, CROCC, NEK2
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| beta-Catenin is a Nek2 substrate involved in centrosome separation.
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| Bahmanyar S, Kaplan DD, Deluca JG, Giddings TH Jr, O'Toole ET, Winey M, Salmon ED, Casey PJ, Nelson WJ, Barth AI.
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| Genes Dev 22(1):91-105. Epub 2007 Dec 17.PMID: 18086858 2008
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14 | CEP135, CEP250
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| A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization.
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| Kim K, Lee S, Chang J, Rhee K.
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| Exp Cell Res 314(20):3692-700. Epub 2008 Oct 1. 2008
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15 | CDK5RAP2, CEP250, CEP68, CROCC
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| Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion.
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| Graser S, Stierhof YD, Nigg EA.
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| J Cell Sci 120(Pt 24):4321-31. Epub 2007 Nov 27.PMID: 18042621 2007
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16 | CEP250, CROCC
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| Rootletin interacts with C-Nap1 and may function as a physical linker between the pair of centrioles/basal bodies in cells.
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| Yang J, Adamian M, Li T.
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| Mol Biol Cell 17(2):1033-40. Epub 2005 Dec 7.PMID: 16339073 2006
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17 | CEP250, CROCC
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| Rootletin forms centriole-associated filaments and functions in centrosome cohesion.
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| Bahe S, Stierhof YD, Wilkinson CJ, Leiss F, Nigg EA.
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| J Cell Biol 171(1):27-33. Epub 2005 Oct 3.PMID: 16203858 2005
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18 | CEP250
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| The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles.
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| Mayor T, Hacker U, Stierhof YD, Nigg EA.
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| J Cell Sci 115(Pt 16):3275-84.
2002
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19 | CEP250
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| C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2.
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| Fry AM, Mayor T, Meraldi P, Stierhof YD, Tanaka K, Nigg EA.
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| J Cell Biol 141(7):1563-74. 1998
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20 | CEP250
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| Autoantibodies to a group of centrosomal proteins in human autoimmune sera reactive with the centrosome.
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| Mack GJ, Rees J, Sandblom O, Balczon R, Fritzler MJ, Rattner JB.
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| Arthritis Rheum 41(3):551-8. 1998
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