Citations for
1CDKN1B, UBE2L3
Stabilization of p27Kip1/CDKN1B by UBCH7/UBE2L3 catalyzed ubiquitinylation: a new paradigm in cell-cycle control.
Whitcomb EA, Tsai YC, Basappa J, Liu K, Le Feuvre AK, Weissman AM, Taylor A.
FASEB J ASEB J. 2018 Aug 16:fj201800960R. doi: 10.1096/fj.201800960R. [Epub ahead of print] 2018
2CDKN1B, SGK1
SGK1-Sensitive Regulation of Cyclin-Dependent Kinase Inhibitor 1B (p27) in Cardiomyocyte Hypertrophy.
Voelkl J, Castor T, Musculus K, Viereck R, Mia S, Feger M, Alesutan I, Lang F.
Cell Physiol Biochem 37(2):603-614. [Epub ahead of print] 2015
3CDKN1B, STMN1
Genetic characterization of p27(kip1) and stathmin in controlling cell proliferation in vivo.
Berton S, Pellizzari I, Fabris L, D'Andrea S, Segatto I, Canzonieri V, Marconi D, Schiappacassi M, Benevol S, Gattei V, Colombatti A, Belletti B, Baldassarre G.
Cell Cycle 13(19):3100-11. doi: 10.4161/15384101.2014.949512. 2014
4CDKN1B, CDKN2B, RB1, SMAD2
Smad2 overexpression reduces the proliferation of the junctional epithelium.
Alotaibi MK, Kitase Y, Shuler CF.
J Dent Res 93(9):898-903. doi: 10.1177/0022034514543016. Epub 2014 Jul 14. 2014
5CDKN1B, COPS5, EXOC3, SIAH1
Sec6 regulated cytoplasmic translocation and degradation of p27 via interactions with Jab1 and Siah1.
Tanaka T, Iino M.
Cell Signal 26(10):2071-85. doi: 10.1016/j.cellsig.2014.06.003. Epub 2014 Jun 18. 2014
6CDKN1B, F3
p27(Kip1) inhibits tissue factor expression.
Breitenstein A, Akhmedov A, Camici GG, Lüscher TF, Tanner FC.
Biochem Biophys Res Commun 439(4):559-63. doi: 10.1016/j.bbrc.2013.09.002. Epub 2013 Sep 8. 2013
7CDKN1B, CDKN2B, KDM2A
Depletion of histone demethylase KDM2A inhibited cell proliferation of stem cells from apical papilla by de-repression of p15INK4B and p27Kip1.
Gao R, Dong R, Du J, Ma P, Wang S, Fan Z.
Mol Cell Biochem 379(1-2):115-22. doi: 10.1007/s11010-013-1633-7. Epub 2013 Apr 5. 2013
8CDKN1B, NOTCH2
A receptor-specific function for Notch2 in mediating vascular smooth muscle cell growth arrest through cyclin-dependent kinase inhibitor 1B.
Boucher JM, Harrington A, Rostama B, Lindner V, Liaw L.
Circ Res 113(8):975-85. doi: 10.1161/CIRCRESAHA.113.301272. Epub 2013 Aug 21. 2013
9CDKN1B, CDKN1C
p57(KIP2) regulates radial glia and intermediate precursor cell cycle dynamics and lower layer neurogenesis in developing cerebral cortex.
Mairet-Coello G, Tury A, Van Buskirk E, Robinson K, Genestine M, DiCicco-Bloom E.
Development 139(3):475-87. doi: 10.1242/dev.067314. 2012
10CDKN1B, KAT2B
PCAF regulates the stability of the transcriptional regulator and cyclin-dependent kinase inhibitor p27 Kip1.
Pérez-Luna M, Aguasca M, Perearnau A, Serratosa J, Martínez-Balbas M, Jesús Pujol M, Bachs O.
Nucleic Acids Res 40(14):6520-33. doi: 10.1093/nar/gks343. Epub 2012 Apr 29. 2012
11CDKN1B, GJA1
Connexin 43 controls the multipolar phase of neuronal migration to the cerebral cortex.
Liu X, Sun L, Torii M, Rakic P.
Proc Natl Acad Sci U S A 109(21):8280-5. doi: 10.1073/pnas.1205880109. Epub 2012 May 7. 2012
12CDKN1B, CIT
p27(Kip1) controls cytokinesis via the regulation of citron kinase activation.
Serres MP, Kossatz U, Chi Y, Roberts JM, Malek NP, Besson A.
J Clin Invest 122(3):844-58. doi: 10.1172/JCI60376. Epub 2012 Feb 1. 2012
13CDKN1B, SKP2, TADA3
Mammalian alteration/deficiency in activation 3 (Ada3) is essential for embryonic development and cell cycle progression.
Mohibi S, Gurumurthy CB, Nag A, Wang J, Mirza S, Mian Y, Quinn M, Katafiasz B, Eudy J, Pandey S, Guda C, Naramura M, Band H, Band V.
J Biol Chem 287(35):29442-56. doi: 10.1074/jbc.M112.378901. Epub 2012 Jun 26. 2012
14CDKN1B, E2F4, RBL2
p27Kip1 represses transcription by direct interaction with p130/E2F4 at the promoters of target genes.
Pippa R, Espinosa L, Gundem G, García-Escudero R, Dominguez A, Orlando S, Gallastegui E, Saiz C, Besson A, Pujol MJ, López-Bigas N, Paramio JM, Bigas A, Bachs O.
Oncogene 31(38):4207-20. doi: 10.1038/onc.2011.582. Epub 2011 Dec 19. 2012
15AIP, CDKN1B, MEN1
Novel mutations in MEN1, CDKN1B and AIP genes in patients with multiple endocrine neoplasia type 1 syndrome in Spain.
Belar O, De La Hoz C, Pérez-Nanclares G, Castańo L, Gaztambide S; Spanish MEN1 Group.
Clin Endocrinol (Oxf) 76(5):719-24. doi: 10.1111/j.1365-2265.2011.04269.x. 2012
16CCNE1, CDKN1B, YWHAE
14-3-3ε plays a role in cardiac ventricular compaction by regulating the cardiomyocyte cell cycle.
Kosaka Y, Cieslik KA, Li L, Lezin G, Maguire CT, Saijoh Y, Toyo-oka K, Gambello MJ, Vatta M, Wynshaw-Boris A, Baldini A, Yost HJ, Brunelli L.
Mol Cell Biol 32(24):5089-102. doi: 10.1128/MCB.00829-12. Epub 2012 Oct 15. 2012
17CDKN1B, MITF
Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny.
Cheli Y, Giuliano S, Botton T, Rocchi S, Hofman V, Hofman P, Bahadoran P, Bertolotto C, Ballotti R.
Oncogene 30(20):2307-18. Epub 2011 Jan 31. Erratum in: Oncogene. 2011 May 19;30(20):2390. Guiliano, S [corrected to Giuliano, S]. 2011
18CDKN1B, CDKN1C, HSPA8
p57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70.
Zou P, Yoshihara H, Hosokawa K, Tai I, Shinmyozu K, Tsukahara F, Maru Y, Nakayama K, Nakayama KI, Suda T.
Cell Stem Cell 9(3):247-61. 2011
19CDKN1B, HIPK2
Homeodomain-interacting protein kinase-2 stabilizes p27(kip1) by its phosphorylation at serine 10 and contributes to cell motility.
Pierantoni GM, Esposito F, Tornincasa M, Rinaldo C, Viglietto G, Soddu S, Fusco A.
J Biol Chem 286(33):29005-13. Epub 2011 Jun 29. 2011
20CDKN1B
Role of T198 modification in the regulation of p27(Kip1) protein stability and function.
Schiappacassi M, Lovisa S, Lovat F, Fabris L, Colombatti A, Belletti B, Baldassarre G.
PLoS One 6(3):e17673. 2011
21CDKN1B, JAK2
Phosphorylation of p27Kip1 by JAK2 directly links cytokine receptor signaling to cell cycle control.
Jäkel H, Weinl C, Hengst L.
Oncogene 30(32):3502-12. doi: 10.1038/onc.2011.68. Epub 2011 Mar 21. 2011
22CDKN1B, RAS
p27(Kip1) is required to maintain proliferative quiescence in the adult cochlea and pituitary.
Oesterle EC, Chien WM, Campbell S, Nellimarla P, Fero ML.
Cell Cycle 10(8):1237-48. Epub 2011 Apr 15. 2011
23CDKN1B, MEN4
p27kip1: a new multiple endocrine neoplasia gene?
Marinoni I, Pellegata NS.
Neuroendocrinology 93(1):19-28. Epub 2010 Oct 27. Review. 2011
24CDKN1B, WWP1
WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) delays cellular senescence by promoting p27(Kip1) degradation in human diploid fibroblasts.
Cao X, Xue L, Han L, Ma L, Chen T, Tong T.
J Biol Chem 286(38):33447-56. Epub 2011 Jul 27. 2011
25CDKN1B, NR4A3, SKP2
Transcriptional regulation of S phase kinase-associated protein 2 by NR4A orphan nuclear receptor NOR1 in vascular smooth muscle cells.
Gizard F, Zhao Y, Findeisen HM, Qing H, Cohn D, Heywood EB, Jones KL, Nomiyama T, Bruemmer D.
J Biol Chem 286(41):35485-93. doi: 10.1074/jbc.M111.295840. Epub 2011 Aug 25. 2011
26CAPN1, CAPN2, CDKN1B
Calpain modulates cyclin-dependent kinase inhibitor 1B (p27(Kip1)) in cells of the osteoblast lineage.
Kashiwagi A, Fein MJ, Shimada M.
Calcif Tissue Int 89(1):36-42. doi: 10.1007/s00223-011-9491-3. Epub 2011 May 5. 2011
27CDKN1B, CDKN1C, E2F1
CDKN1C negatively regulates RNA polymerase II C-terminal domain phosphorylation in an E2F1-dependent manner.
Ma Y, Chen L, Wright GM, Pillai SR, Chellappan SP, Cress WD.
J Biol Chem 285(13):9813-22. Epub 2010 Jan 27.PMID: 20106982 2010
28CDKN1B, MEN4
MEN-4 and other multiple endocrine neoplasias due to cyclin-dependent kinase inhibitors (p27(Kip1) and p18(INK4C)) mutations.
Georgitsi M.
Best Pract Res Clin Endocrinol Metab 24(3):425-37. Review. 2010
29CDKN1B, MEN4
A novel germline CDKN1B mutation causing multiple endocrine tumors: clinical, genetic and functional characterization.
Molatore S, Marinoni I, Lee M, Pulz E, Ambrosio MR, degli Uberti EC, Zatelli MC, Pellegata NS.
Hum Mutat 31(11):E1825-35. 2010
30CDKN1B
Regulation of memory CD8 T-cell differentiation by cyclin-dependent kinase inhibitor p27Kip1.
Singh A, Jatzek A, Plisch EH, Srinivasan R, Svaren J, Suresh M.
Mol Cell Biol 30(21):5145-59. Epub 2010 Aug 30. 2010
31CDKN1B
CCND1 and CDKN1B polymorphisms and risk of breast cancer.
Canbay E, Eraltan IY, Cercel A, Isbir T, Gazioglu E, Aydogan F, Cacina C, Cengiz A, Ferahman M, Zengin E, Unal H.
Anticancer Res 30(7):3093-8. 2010
32CDKN1B, CFL1
Regulated expression of cofilin and the consequent regulation of p27(kip1) are essential for G(1) phase progression.
Tsai CH, Chiu SJ, Liu CC, Sheu TJ, Hsieh CH, Keng PC, Lee YJ.
Cell Cycle 8(15):2365-74. Epub 2009 Aug 20.PMID: 19556892 2009
33CDKN1B
Localization of p27kip1 in the developing avian retina: sustained expression in the mature tissue.
Portugal LC, Ventura AL.
Neurosci Lett 466(1):35-40. Epub 2009 Sep 27. 2009
34CDKN1B
The function of p27 KIP1 during tumor development.
Lee J, Kim SS.
Exp Mol Med 41(11):765-71. Review. 2009
35CDKN1B
p27Kip1 constrains proliferation of neural progenitor cells in adult brain under homeostatic and ischemic conditions.
Qiu J, Takagi Y, Harada J, Topalkara K, Wang Y, Sims JR, Zheng G, Huang P, Ling Y, Scadden DT, Moskowitz MA, Cheng T.
Stem Cells 27(4):920-7. 2009
36CDKN1B
Inhibition of p27Kip1 gene transcription by mitogens.
Bagui TK, Cui D, Roy S, Mohapatra S, Shor AC, Ma L, Pledger WJ.
Cell Cycle 8(1):115-24. 2009
37CDKN1B, STAT1
Stat1 phosphorylation determines Ras oncogenicity by regulating p27 kip1.
Wang S, Raven JF, Durbin JE, Koromilas AE.
PLoS One 3(10):e3476. Epub 2008 Oct 22. 2008
38CDKN1B, PDPK1
PDK1 regulates cell proliferation and cell cycle progression through control of cyclin D1 and p27Kip1 expression.
Nakamura K, Sakaue H, Nishizawa A, Matsuki Y, Gomi H, Watanabe E, Hiramatsua R, Tamamori-Adachi M, Kitajima S, Noda T, Ogawa W, Kasuga M.
J Biol Chem 283(25):17702-11. Epub 2008 Apr 22. 2008
39CDKN1B,TSC2
p27Kip1 localization depends on the tumor suppressor protein tuberin.
Rosner M, Freilinger A, Hanneder M, Fujita N, Lubec G, Tsuruo T, Hengstschlager M.
Hum Mol Genet 16(13):1541-56. Epub 2007 Apr 30. 2007
40CDKN1B, CKS1B, SKP2
CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms.
Zhan F, Colla S, Wu X, Chen B, Stewart JP, Kuehl WM, Barlogie B, Shaughnessy JD Jr.
Blood 109(11):4995-5001. Epub 2007 Feb 15. 2007
41CDKN1B
Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans.
Pellegata NS, Quintanilla-Martinez L, Siggelkow H, Samson E, Bink K, Hofler H, Fend F, Graw J, Atkinson MJ.
Proc Natl Acad Sci U S A 103(42):15558-63. Epub 2006 Oct 9. 2006
42CDKN1A, CDKN1B, CDKN2A, RB1
Age differences in cyclin-dependent kinase inhibitor expression and rb hyperphosphorylation in human corneal endothelial cells.
Enomoto K, Mimura T, Harris DL, Joyce NC.
Invest Ophthalmol Vis Sci 47(10):4330-40. 2006
43OLIG2, CDKN1B
A novel function of OLIG2 to suppress human glial tumor cell growth via p27Kip1 transactivation.
Tabu K, Ohnishi A, Sunden Y, Suzuki T, Tsuda M, Tanaka S, Sakai T, Nagashima K, Sawa H.
J Cell Sci 119(Pt 7):1433-41. 2006
44CDKN1B, MCM7
The cell cycle regulator p27Kip1 interacts with MCM7, a DNA replication licensing factor, to inhibit initiation of DNA replication.
Nallamshetty S, Crook M, Boehm M, Yoshimoto T, Olive M, Nabel EG.
FEBS Lett 579(29):6529-36. Epub 2005 Nov 2. 2005
45CDKN1B, CDKN1C, RNF123
Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase.
Kotoshiba S, Kamura T, Hara T, Ishida N, Nakayama KI.
J Biol Chem 280(18):17694-700. Epub 2005 Mar 3. 2005
46TSC2, SKP2, CDKN1B
Tuberin binds p27 and negatively regulates its interaction with the SCF component Skp2.
Rosner M, Hengstschlager M.
J Biol Chem 279(47):48707-15. Epub 2004 Sep 8. 2004
47SKP2, CDKN1B, CKS1B
High expression of Cks1 in human non-small cell lung carcinomas.
Inui N, Kitagawa K, Miwa S, Hattori T, Chida K, Nakamura H, Kitagawa M.
Biochem Biophys Res Commun 303(3):978-84. 2003
48CDKN1A, CDKN1B
CDKN1A and CDKN1B polymorphisms and risk of advanced prostate carcinoma.
Kibel AS, Suarez BK, Belani J, Oh J, Webster R, Brophy-Ebbers M, Guo C, Catalona WJ, Picus J, Goodfellow PJ.
Cancer Res 63(9):2033-6. 2003
49CDKN1B, RPS6KA1
Phosphorylation of p27Kip1 at threonine 198 by p90 ribosomal protein S6 kinases promotes its binding to 14-3-3 and cytoplasmic localization.
Fujita N, Sato S, Tsuruo T.
J Biol Chem 278(49):49254-60. Epub 2003 Sep 22. 2003
50BRCA1, CDKN1B
BRCA1 transactivates the cyclin-dependent kinase inhibitor p27(Kip1).
Williamson EA, Dadmanesh F, Koeffler HP.
Oncogene 21(20):3199-206. 2002
51CDKN1B, CUL1, NEDD8, SKP2
The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1.
Yang X, Menon S, Lykke-Andersen K, Tsuge T, Di Xiao, Wang X, Rodriguez-Suarez RJ, Zhang H, Wei N.
Curr Biol 12(8):667-72. 2002
52CDKN1B, COPS5, UCHL1
Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1).
Caballero OL, Resto V, Patturajan M, Meerzaman D, Guo MZ, Engles J, Yochem R, Ratovitski E, Sidransky D, Jen J.
Oncogene 21(19):3003-10. 2002
53CDKN1B, COPS5, JUN
Jab1 co-activation of c-Jun is abrogated by the serine 10-phosphorylated form of p27Kip1.
Chopra S, Fernandez De Mattos S, Lam EW, Mann DJ.
J Biol Chem 277(36):32413-6. 2002
54CDKN1B
p27(Kip1) enhances myelin basic protein gene promoter activity.
Miskimins R, Srinivasan R, Marin-Husstege M, Miskimins WK, Casaccia-Bonnefil P.
J Neurosci Res 67(1):100-5. 2002
55CDKN1B
Cloning and functional expression of a degradation-resistant novel isoform of p27Kip1.
Hirano K, Hirano M, Zeng Y, Nishimura J, Hara K, Muta K, Nawata H, Kanaide H.
Biochem J 353(Pt 1):51-57. 2001
56CDKN1B
p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes.
Boussiotis VA, Freeman GJ, Taylor PA, Berezovskaya A, Grass I, Blazar BR, Nadler LM.
Nat Med 6(3):290-7. 2000
57CDKN1B
Involvement of retinoblastoma protein in p27Kip1-induced apoptosis.
Oh S, Kim TK, Hwang DS, Yim J.
Cancer Lett 148(1):105-10. 2000
58CDKN1B
Loss of p27(KIP1) expression predicts poor prognosis in patients with esophageal squamous cell carcinoma.
Shamma A, Doki Y, Tsujinaka T, Shiozaki H, Inoue M, Yano M, Kawanishi K, Monden M.
Oncology 58(2):152-8. 2000
59CDKN1B, COPS5, MIF
Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1.
Kleemann R, Hausser A, Geiger G, Mischke R, Burger-Kentischer A, Flieger O, Johannes FJ, Roger T, Calandra T, Kapurniotu A, Grell M, Finkelmeier D, Brunner H, Bernhagen J.
Nature 408(6809):211-6. 2000
60CDKN1B, FOXO3, FOXO4
AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1.
Medema RH, Kops GJ, Bos JL, Burgering BM.
Nature 404(6779):782-7. 2000
61CDKN1B, AP3S1P, ETV6, LRP6
A physical, transcript, and deletion map of chromosome region 12p12. 3 flanked by ETV6 and CDKN1B: hypermethylation of the LRP6 CpG island in two leukemia patients with hemizygous del(12p).
Baens M, et al.
Genomics 56(1):40-50. 1999
62CDKN1B, ITGB1
p27(kip1) acts as a downstream effector of and is coexpressed with the beta1C integrin in prostatic adenocarcinoma.
Fornaro M, Tallini G, Zheng DQ, Flanagan WM, Manzotti M, Languino LR.
J Clin Invest 103(3):321-9. 1999
63CDKN1B, TGFBR2
Transforming growth factor beta receptors and p27kip in thyroid carcinoma.
Muro-Cacho CA, et al.
Arch Otolaryngol Head Neck Surg 125(1):76-81. 1999
64CDKN1B
p27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers.
Lloyd RV, et al.
Am J Pathol 154(2):313-23. Review. 1999
65CDKN1B
Low p27 expression correlates with poor prognosis for patients with oral tongue squamous cell carcinoma.
Mineta H, et al.
Cancer 85(5):1011-7. 1999
66CDKN1B
Loss of p27Kip1 expression independently predicts poor prognosis for patients with resectable pancreatic adenocarcinoma.
Lu CD, et al.
Cancer 85(6):1250-60. 1999
67CDKN1B
Two short sequences have positive effects on the human p27Kip1 gene transcription.
Ito E, et al.
Gene 228(1-2):93-100. 1999
68CDKN1B
Regulatory role of p27kip1 in the mouse and human testis.
Beumer TL, et al.
Endocrinology 140(4):1834-40. 1999
69CDKN1B, CDKN1A
Expression of p21(Cip1/Waf1/Sdi1) and p27(Kip1) cyclin-dependent kinase inhibitors during human hematopoiesis.
Taniguchi T, et al.
Blood 93(12):4167-78. 1999
70GPR19, CDKN1B
Physical mapping of the G-protein coupled receptor 19 (GPR19) in the chromosome 12p12.3 region frequently rearranged in cancer cells.
Montpetit A, et al.
Hum Genet 105(1-2):162-4. 1999
71CDKN1B
Loss of P27Kip1 expression correlates with tumor grade and with reduced disease-free survival in primary superficial bladder cancers.
Sgambato A, et al.
Cancer Res 59(13):3245-50 1999
72CCND3, CDKN1B
Anomalous high p27/KIP1 expression in a subset of aggressive B-cell lymphomas is associated with cyclin D3 overexpression. p27/KIP1-cyclin D3 colocalization in tumor cells.
Sanchez-Beato M, et al.
Blood 94(2):765-72 1999
73CDKN1B
Proteasome-dependent degradation of p27/kip1 in gliomas.
Piva R, et al.
J Neuropathol Exp Neurol 58(7):691-6 1999
74CDKN1B, SKP2
SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27.
Carrano AC, Eytan E, Hershko A, Pagano M.
Nat Cell Biol 1(4):193-9. 1999
75CDKN1B
Mutation and expression analysis of the p27/kip1 gene in corticotrophin-secreting tumours.
Dahia PLM, et al.
Oncogene 16 : 69-76. 1998
76CDKN1B, CDKN1C
Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development.
Zhang P, Wong C, DePinho RA, Harper JW, Elledge SJ.
Genes Dev 12 : 3162-3167. 1998
77CDKN1B
Reduced expression of cyclin-dependent kinase inhibitor p27Kip1 is an indicator of malignant behavior in oral squamous cell carcinoma.
Kudo Y, et al.
Cancer 83 : 2447-2455. 1998
78PPARA, CDKN1B, VHL
Peroxisome proliferator-activated receptor alpha-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis.
Costet P, et al.
J Biol Chem 273(45):29577-85. 1998
79CDKN1B, ETV6
Deletions of CDKN1B and ETV6 in acute myeloid leukemia and myelodysplastic syndromes without cytogenetic evidence of 12p abnormalities.
Andreasson P, Johansson B, Arheden K, Billstrom R, Mitelman F, Hoglund M.
Genes Chromosomes Cancer 19(2):77-83. 1997
80CDKN1B
Molecular cloning and characterization of the human p27Kip1 gene promoter.
Minami S, Ohtani-Fujita N, Igata E, Tamaki T, Sakai T.
FEBS Lett 411(1):1-6. 1997
81CDKN1B
Mutational analysis of the human cyclin-dependent kinase inhibitor p27kip1 in primary breast carcinomas.
Ferrando AA, et al.
Hum Genet 97 : 91-94. 1996
82CDKN1B
Characterization of the human p57KIP2 gene : alternative splicing, insertion/deletion polymorphisms in VNTR sequences in the coding region, and mutational analysis.
Tokino T, et al.
Hum Genet 97 : 625-631. 1996
83CDKN1B, TSG12B
Frequent loss of heterozygosity in region of the KIP1 locus in non-small cell lung cancer : evidence for a new tumor suppressor gene on the short arm of chromosome 12.
Takeuchi S, et al.
Cancer Res 56 : 738-740. 1996
84CDKN1B
Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, p57KIP2, on chromosome 11p15.
Matsuoka S, et al.
Proc Natl Acad Sci U S A 93 : 3026-3030. 1996
85CDKN1B
Genomic imprinting of human p57KIP2 and its reduced expression in Wilms'tumors.
Hatada I, et al.
Hum Mol Genet 5 : 783-788. 1996
86D12S178, ARHGDIB, ETV6, CDKN1B
The ETV6, CDKN1B and D12S178 loci are involved in a segment commonly deleted in various 12p aberrations in different hematological malignancies.
Wlodarska I, et al.
Cytogenet Cell Genet 72 : 229-235. 1996
87CDKN1B, ETV6, TSG12B
Acute lymphoblastic leukemia of childhood : identification of two distinct regions of deletion on the short arm of chromosome 12 in the region of TEL and KIP1.
Takeuchi S, et al.
Blood 87 : 3368-3374. 1996
88CDKN1B
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27Kip1-deficient mice.
Fero ML, et al.
Cell 85 : 733-744. 1996
89CDKN1B
Selective maternal-allele loss in human lung cancers of the maternally expressed p57KIP2 gene at 11p15.5.
Kondo M, et al.
Oncogene 12 : 1365-1368. 1996
90CDKN1B
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function pf p27Kip1.
Kiyokawa H, et al.
Cell 85 : 721-732. 1996
91CDKN1B
Mice lacking p27Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors.
Nakayama K, et al.
Cell 85 : 707-720. 1996
92CDKN1B,ETV6
TEL and K1P1 define the smallest region of deletions on 12p13 in hematopoietic malignancies.
Sato Y, et al.
Blood 86 : 1525-1533. 1995
93CDKN1B
Localization of the CDNK4/p27Kip1 gene to human chromosome 12p12.3.
Martin E, et al.
Hum Genet 96 : 668-670. 1995
94CDKN1B, TSG12B
Loss of heterozygosity in the chromosomal region 12p12-13 is very common in childhood acute lymphoblastic leukemia and permits the precise localization of a tumor-suppressor gene distinct from p27KIP1.
CavŽ H, et al.
Blood 86 : 3869-3875. 1995
95CDKN1B
p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene.
Matsuoka S, et al.
Genes Dev 9 : 650-662. 1995
96CDKN1B
Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution.
Lee MH, et al.
Genes Dev 9 : 639-649. 1995
97CDK10, CDK9, CDK3, CDK6, CDKN1B
Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer.
Bullrich F, et al.
Cancer Res 55 : 1199-1205. 1995
98CDKN1B
p27Kip1 : chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors.
Ponce-Castaneda MV, et al.
Cancer Res 55 : 1211-1214. 1995
99CDKN1B
Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias.
Pietenpol JA, et al.
Cancer Res 55 : 1206-1210. 1995
100CDKN1B
Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies.
Kawamata N, et al.
Cancer Res 55 : 2266-2269. 1995
101CDKN1B
Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation.
Kato JY, et al.
Cell 79 : 487-496. 1994
102CDKN1B
Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals.
Polyak K, et al.
Cell 78 : 59-66. 1994
103CDKN1B
p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity, is related to p21.
Toyoshima H, et al.
Cell 78 : 67-74. 1994