| 1 | CDKN1B, PUM1
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| PUM1 represses CDKN1B translation and contributes to prostate cancer progression
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| Li X, Yang J, Chen X, Cao D, Xu EY.
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| J Biomed Res. Jul 16;35(5):371-382. doi: 10.7555/JBR.35.20210067. 2021
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| 2 | CDKN1B, MAST1
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| MAST1 modulates neuronal differentiation and cell cycle exit via P27 in neuroblastoma cells
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| Jing T, Ma J, Zhao H, Zhang J, Jiang N, Ma D.
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| FEBS Open Bio. Jun;10(6):1104-1114. doi: 10.1002/2211-5463.12860. Epub 2020 Apr 29. 2020
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| 3 | CDKN1B, UBE2L3
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| Stabilization of p27Kip1/CDKN1B by UBCH7/UBE2L3 catalyzed ubiquitinylation: a new paradigm in cell-cycle control.
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| Whitcomb EA, Tsai YC, Basappa J, Liu K, Le Feuvre AK, Weissman AM, Taylor A.
|
| FASEB J ASEB J. 2018 Aug 16:fj201800960R. doi: 10.1096/fj.201800960R. [Epub ahead of print]
2018
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| 4 | CDKN1B, GJA4
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| Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification.
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| Fang JS, Coon BG, Gillis N, Chen Z, Qiu J, Chittenden TW, Burt JM, Schwartz MA, Hirschi KK.
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| Nat Commun. Dec 15;8(1):2149. doi: 10.1038/s41467-017-01742-7 2017
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| 5 | CDKN1B, SGK1
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| SGK1-Sensitive Regulation of Cyclin-Dependent Kinase Inhibitor 1B (p27) in Cardiomyocyte Hypertrophy.
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| Voelkl J, Castor T, Musculus K, Viereck R, Mia S, Feger M, Alesutan I, Lang F.
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| Cell Physiol Biochem 37(2):603-614. [Epub ahead of print]
2015
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| 6 | CDKN1B, STMN1
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| Genetic characterization of p27(kip1) and stathmin in controlling cell proliferation in vivo.
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| Berton S, Pellizzari I, Fabris L, D'Andrea S, Segatto I, Canzonieri V, Marconi D, Schiappacassi M, Benevol S, Gattei V, Colombatti A, Belletti B, Baldassarre G.
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| Cell Cycle 13(19):3100-11. doi: 10.4161/15384101.2014.949512.
2014
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| 7 | CDKN1B, CDKN2B, RB1, SMAD2
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| Smad2 overexpression reduces the proliferation of the junctional epithelium.
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| Alotaibi MK, Kitase Y, Shuler CF.
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| J Dent Res 93(9):898-903. doi: 10.1177/0022034514543016. Epub 2014 Jul 14.
2014
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| 8 | CDKN1B, COPS5, EXOC3, SIAH1
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| Sec6 regulated cytoplasmic translocation and degradation of p27 via interactions with Jab1 and Siah1.
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| Tanaka T, Iino M.
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| Cell Signal 26(10):2071-85. doi: 10.1016/j.cellsig.2014.06.003. Epub 2014 Jun 18.
2014
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| 9 | CDKN1B, F3
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| p27(Kip1) inhibits tissue factor expression.
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| Breitenstein A, Akhmedov A, Camici GG, Lüscher TF, Tanner FC.
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| Biochem Biophys Res Commun 439(4):559-63. doi: 10.1016/j.bbrc.2013.09.002. Epub 2013 Sep 8.
2013
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| 10 | CDKN1B, CDKN2B, KDM2A
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| Depletion of histone demethylase KDM2A inhibited cell proliferation of stem cells from apical papilla by de-repression of p15INK4B and p27Kip1.
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| Gao R, Dong R, Du J, Ma P, Wang S, Fan Z.
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| Mol Cell Biochem 379(1-2):115-22. doi: 10.1007/s11010-013-1633-7. Epub 2013 Apr 5.
2013
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| 11 | CDKN1B, NOTCH2
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| A receptor-specific function for Notch2 in mediating vascular smooth muscle cell growth arrest through cyclin-dependent kinase inhibitor 1B.
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| Boucher JM, Harrington A, Rostama B, Lindner V, Liaw L.
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| Circ Res 113(8):975-85. doi: 10.1161/CIRCRESAHA.113.301272. Epub 2013 Aug 21.
2013
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| 12 | CDKN1B, CDKN1C
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| p57(KIP2) regulates radial glia and intermediate precursor cell cycle dynamics and lower layer neurogenesis in developing cerebral cortex.
|
| Mairet-Coello G, Tury A, Van Buskirk E, Robinson K, Genestine M, DiCicco-Bloom E.
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| Development 139(3):475-87. doi: 10.1242/dev.067314.
2012
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| 13 | CDKN1B, KAT2B
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| PCAF regulates the stability of the transcriptional regulator and cyclin-dependent kinase inhibitor p27 Kip1.
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| Pérez-Luna M, Aguasca M, Perearnau A, Serratosa J, Martínez-Balbas M, Jesús Pujol M, Bachs O.
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| Nucleic Acids Res 40(14):6520-33. doi: 10.1093/nar/gks343. Epub 2012 Apr 29. 2012
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| 14 | CDKN1B, GJA1
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| Connexin 43 controls the multipolar phase of neuronal migration to the cerebral cortex.
|
| Liu X, Sun L, Torii M, Rakic P.
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| Proc Natl Acad Sci U S A 109(21):8280-5. doi: 10.1073/pnas.1205880109. Epub 2012 May 7. 2012
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| 15 | CDKN1B, CIT
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| p27(Kip1) controls cytokinesis via the regulation of citron kinase activation.
|
| Serres MP, Kossatz U, Chi Y, Roberts JM, Malek NP, Besson A.
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| J Clin Invest 122(3):844-58. doi: 10.1172/JCI60376. Epub 2012 Feb 1.
2012
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| 16 | CDKN1B, SKP2, TADA3
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| Mammalian alteration/deficiency in activation 3 (Ada3) is essential for embryonic development and cell cycle progression.
|
| Mohibi S, Gurumurthy CB, Nag A, Wang J, Mirza S, Mian Y, Quinn M, Katafiasz B, Eudy J, Pandey S, Guda C, Naramura M, Band H, Band V.
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| J Biol Chem 287(35):29442-56. doi: 10.1074/jbc.M112.378901. Epub 2012 Jun 26. 2012
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| 17 | CDKN1B, E2F4, RBL2
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| p27Kip1 represses transcription by direct interaction with p130/E2F4 at the promoters of target genes.
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| Pippa R, Espinosa L, Gundem G, García-Escudero R, Dominguez A, Orlando S, Gallastegui E, Saiz C, Besson A, Pujol MJ, López-Bigas N, Paramio JM, Bigas A, Bachs O.
|
| Oncogene 31(38):4207-20. doi: 10.1038/onc.2011.582. Epub 2011 Dec 19.
2012
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| 18 | AIP, CDKN1B, MEN1
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| Novel mutations in MEN1, CDKN1B and AIP genes in patients with multiple endocrine neoplasia type 1 syndrome in Spain.
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| Belar O, De La Hoz C, Pérez-Nanclares G, Castańo L, Gaztambide S; Spanish MEN1 Group.
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| Clin Endocrinol (Oxf) 76(5):719-24. doi: 10.1111/j.1365-2265.2011.04269.x.
2012
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| 19 | CCNE1, CDKN1B, YWHAE
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| 14-3-3ε plays a role in cardiac ventricular compaction by regulating the cardiomyocyte cell cycle.
|
| Kosaka Y, Cieslik KA, Li L, Lezin G, Maguire CT, Saijoh Y, Toyo-oka K, Gambello MJ, Vatta M, Wynshaw-Boris A, Baldini A, Yost HJ, Brunelli L.
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| Mol Cell Biol 32(24):5089-102. doi: 10.1128/MCB.00829-12. Epub 2012 Oct 15.
2012
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| 20 | CDKN1B, MITF
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| Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny.
|
| Cheli Y, Giuliano S, Botton T, Rocchi S, Hofman V, Hofman P, Bahadoran P, Bertolotto C, Ballotti R.
|
| Oncogene 30(20):2307-18. Epub 2011 Jan 31. Erratum in: Oncogene. 2011 May 19;30(20):2390. Guiliano, S [corrected to Giuliano, S].
2011
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| 21 | CDKN1B, CDKN1C, HSPA8
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| p57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70.
|
| Zou P, Yoshihara H, Hosokawa K, Tai I, Shinmyozu K, Tsukahara F, Maru Y, Nakayama K, Nakayama KI, Suda T.
|
| Cell Stem Cell 9(3):247-61.
2011
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| 22 | CDKN1B, HIPK2
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| Homeodomain-interacting protein kinase-2 stabilizes p27(kip1) by its phosphorylation at serine 10 and contributes to cell motility.
|
| Pierantoni GM, Esposito F, Tornincasa M, Rinaldo C, Viglietto G, Soddu S, Fusco A.
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| J Biol Chem 286(33):29005-13. Epub 2011 Jun 29.
2011
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| 23 | CDKN1B
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| Role of T198 modification in the regulation of p27(Kip1) protein stability and function.
|
| Schiappacassi M, Lovisa S, Lovat F, Fabris L, Colombatti A, Belletti B, Baldassarre G.
|
| PLoS One 6(3):e17673.
2011
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| 24 | CDKN1B, JAK2
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| Phosphorylation of p27Kip1 by JAK2 directly links cytokine receptor signaling to cell cycle control.
|
| Jäkel H, Weinl C, Hengst L.
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| Oncogene 30(32):3502-12. doi: 10.1038/onc.2011.68. Epub 2011 Mar 21.
2011
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| 25 | CDKN1B, RAS
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| p27(Kip1) is required to maintain proliferative quiescence in the adult cochlea and pituitary.
|
| Oesterle EC, Chien WM, Campbell S, Nellimarla P, Fero ML.
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| Cell Cycle 10(8):1237-48. Epub 2011 Apr 15.
2011
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| 26 | CDKN1B, MEN4
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| p27kip1: a new multiple endocrine neoplasia gene?
|
| Marinoni I, Pellegata NS.
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| Neuroendocrinology 93(1):19-28. Epub 2010 Oct 27. Review.
2011
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| 27 | CDKN1B, WWP1
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| WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) delays cellular senescence by promoting p27(Kip1) degradation in human diploid fibroblasts.
|
| Cao X, Xue L, Han L, Ma L, Chen T, Tong T.
|
| J Biol Chem 286(38):33447-56. Epub 2011 Jul 27.
2011
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| 28 | CDKN1B, NR4A3, SKP2
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| Transcriptional regulation of S phase kinase-associated protein 2 by NR4A orphan nuclear receptor NOR1 in vascular smooth muscle cells.
|
| Gizard F, Zhao Y, Findeisen HM, Qing H, Cohn D, Heywood EB, Jones KL, Nomiyama T, Bruemmer D.
|
| J Biol Chem 286(41):35485-93. doi: 10.1074/jbc.M111.295840. Epub 2011 Aug 25.
2011
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| 29 | CAPN1, CAPN2, CDKN1B
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| Calpain modulates cyclin-dependent kinase inhibitor 1B (p27(Kip1)) in cells of the osteoblast lineage.
|
| Kashiwagi A, Fein MJ, Shimada M.
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| Calcif Tissue Int 89(1):36-42. doi: 10.1007/s00223-011-9491-3. Epub 2011 May 5. 2011
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| 30 | CDKN1B, CDKN1C, E2F1
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| CDKN1C negatively regulates RNA polymerase II C-terminal domain phosphorylation in an E2F1-dependent manner.
|
| Ma Y, Chen L, Wright GM, Pillai SR, Chellappan SP, Cress WD.
|
| J Biol Chem 285(13):9813-22. Epub 2010 Jan 27.PMID: 20106982 2010
|
| 31 | CDKN1B, MEN4
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| MEN-4 and other multiple endocrine neoplasias due to cyclin-dependent kinase inhibitors (p27(Kip1) and p18(INK4C)) mutations.
|
| Georgitsi M.
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| Best Pract Res Clin Endocrinol Metab 24(3):425-37. Review.
2010
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| 32 | CDKN1B, MEN4
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| A novel germline CDKN1B mutation causing multiple endocrine tumors: clinical, genetic and functional characterization.
|
| Molatore S, Marinoni I, Lee M, Pulz E, Ambrosio MR, degli Uberti EC, Zatelli MC, Pellegata NS.
|
| Hum Mutat 31(11):E1825-35.
2010
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| 33 | CDKN1B
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| Regulation of memory CD8 T-cell differentiation by cyclin-dependent kinase inhibitor p27Kip1.
|
| Singh A, Jatzek A, Plisch EH, Srinivasan R, Svaren J, Suresh M.
|
| Mol Cell Biol 30(21):5145-59. Epub 2010 Aug 30.
2010
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| 34 | CDKN1B
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| CCND1 and CDKN1B polymorphisms and risk of breast cancer.
|
| Canbay E, Eraltan IY, Cercel A, Isbir T, Gazioglu E, Aydogan F, Cacina C, Cengiz A, Ferahman M, Zengin E, Unal H.
|
| Anticancer Res 30(7):3093-8.
2010
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| 35 | CDKN1B, CFL1
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| Regulated expression of cofilin and the consequent regulation of p27(kip1) are essential for G(1) phase progression.
|
| Tsai CH, Chiu SJ, Liu CC, Sheu TJ, Hsieh CH, Keng PC, Lee YJ.
|
| Cell Cycle 8(15):2365-74. Epub 2009 Aug 20.PMID: 19556892 2009
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| 36 | CDKN1B
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| Localization of p27kip1 in the developing avian retina: sustained expression in the mature tissue.
|
| Portugal LC, Ventura AL.
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| Neurosci Lett 466(1):35-40. Epub 2009 Sep 27.
2009
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| 37 | CDKN1B
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| The function of p27 KIP1 during tumor development.
|
| Lee J, Kim SS.
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| Exp Mol Med 41(11):765-71. Review.
2009
|
| 38 | CDKN1B
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| p27Kip1 constrains proliferation of neural progenitor cells in adult brain under homeostatic and ischemic conditions.
|
| Qiu J, Takagi Y, Harada J, Topalkara K, Wang Y, Sims JR, Zheng G, Huang P, Ling Y, Scadden DT, Moskowitz MA, Cheng T.
|
| Stem Cells 27(4):920-7.
2009
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| 39 | CDKN1B
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| Inhibition of p27Kip1 gene transcription by mitogens.
|
| Bagui TK, Cui D, Roy S, Mohapatra S, Shor AC, Ma L, Pledger WJ.
|
| Cell Cycle 8(1):115-24.
2009
|
| 40 | CDKN1B, STAT1
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| Stat1 phosphorylation determines Ras oncogenicity by regulating p27 kip1.
|
| Wang S, Raven JF, Durbin JE, Koromilas AE.
|
| PLoS One 3(10):e3476. Epub 2008 Oct 22.
2008
|
| 41 | CDKN1B, PDPK1
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| PDK1 regulates cell proliferation and cell cycle progression through control of cyclin D1 and p27Kip1 expression.
|
| Nakamura K, Sakaue H, Nishizawa A, Matsuki Y, Gomi H, Watanabe E, Hiramatsua R, Tamamori-Adachi M, Kitajima S, Noda T, Ogawa W, Kasuga M.
|
| J Biol Chem 283(25):17702-11. Epub 2008 Apr 22. 2008
|
| 42 | CDKN1B,TSC2
|
| p27Kip1 localization depends on the tumor suppressor protein tuberin.
|
| Rosner M, Freilinger A, Hanneder M, Fujita N, Lubec G, Tsuruo T, Hengstschlager M.
|
| Hum Mol Genet 16(13):1541-56. Epub 2007 Apr 30. 2007
|
| 43 | CDKN1B, CKS1B, SKP2
|
| CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms.
|
| Zhan F, Colla S, Wu X, Chen B, Stewart JP, Kuehl WM, Barlogie B, Shaughnessy JD Jr.
|
| Blood 109(11):4995-5001. Epub 2007 Feb 15.
2007
|
| 44 | CDKN1B
|
| Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans.
|
| Pellegata NS, Quintanilla-Martinez L, Siggelkow H, Samson E, Bink K, Hofler H, Fend F, Graw J, Atkinson MJ.
|
| Proc Natl Acad Sci U S A 103(42):15558-63. Epub 2006 Oct 9. 2006
|
| 45 | CDKN1A, CDKN1B, CDKN2A, RB1
|
| Age differences in cyclin-dependent kinase inhibitor expression and rb hyperphosphorylation in human corneal endothelial cells.
|
| Enomoto K, Mimura T, Harris DL, Joyce NC.
|
| Invest Ophthalmol Vis Sci 47(10):4330-40. 2006
|
| 46 | OLIG2, CDKN1B
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| A novel function of OLIG2 to suppress human glial tumor cell growth via p27Kip1 transactivation.
|
| Tabu K, Ohnishi A, Sunden Y, Suzuki T, Tsuda M, Tanaka S, Sakai T, Nagashima K, Sawa H.
|
| J Cell Sci 119(Pt 7):1433-41. 2006
|
| 47 | CDKN1B, MCM7
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| The cell cycle regulator p27Kip1 interacts with MCM7, a DNA replication licensing factor, to inhibit initiation of DNA replication.
|
| Nallamshetty S, Crook M, Boehm M, Yoshimoto T, Olive M, Nabel EG.
|
| FEBS Lett 579(29):6529-36. Epub 2005 Nov 2. 2005
|
| 48 | CDKN1B, CDKN1C, RNF123
|
| Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase.
|
| Kotoshiba S, Kamura T, Hara T, Ishida N, Nakayama KI.
|
| J Biol Chem 280(18):17694-700. Epub 2005 Mar 3.
2005
|
| 49 | TSC2, SKP2, CDKN1B
|
| Tuberin binds p27 and negatively regulates its interaction with the SCF component Skp2.
|
| Rosner M, Hengstschlager M.
|
| J Biol Chem 279(47):48707-15. Epub 2004 Sep 8. 2004
|
| 50 | SKP2, CDKN1B, CKS1B
|
| High expression of Cks1 in human non-small cell lung carcinomas.
|
| Inui N, Kitagawa K, Miwa S, Hattori T, Chida K, Nakamura H, Kitagawa M.
|
| Biochem Biophys Res Commun 303(3):978-84. 2003
|
| 51 | CDKN1A, CDKN1B
|
| CDKN1A and CDKN1B polymorphisms and risk of advanced prostate carcinoma.
|
| Kibel AS, Suarez BK, Belani J, Oh J, Webster R, Brophy-Ebbers M, Guo C, Catalona WJ, Picus J, Goodfellow PJ.
|
| Cancer Res 63(9):2033-6. 2003
|
| 52 | CDKN1B, RPS6KA1
|
| Phosphorylation of p27Kip1 at threonine 198 by p90 ribosomal protein S6 kinases promotes its binding to 14-3-3 and cytoplasmic localization.
|
| Fujita N, Sato S, Tsuruo T.
|
| J Biol Chem 278(49):49254-60. Epub 2003 Sep 22. 2003
|
| 53 | BRCA1, CDKN1B
|
| BRCA1 transactivates the cyclin-dependent kinase inhibitor p27(Kip1).
|
| Williamson EA, Dadmanesh F, Koeffler HP.
|
| Oncogene 21(20):3199-206. 2002
|
| 54 | CDKN1B, CUL1, NEDD8, SKP2
|
| The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1.
|
| Yang X, Menon S, Lykke-Andersen K, Tsuge T, Di Xiao, Wang X, Rodriguez-Suarez RJ, Zhang H, Wei N.
|
| Curr Biol 12(8):667-72. 2002
|
| 55 | CDKN1B, COPS5, UCHL1
|
| Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1).
|
| Caballero OL, Resto V, Patturajan M, Meerzaman D, Guo MZ, Engles J, Yochem R, Ratovitski E, Sidransky D, Jen J.
|
| Oncogene 21(19):3003-10. 2002
|
| 56 | CDKN1B, COPS5, JUN
|
| Jab1 co-activation of c-Jun is abrogated by the serine 10-phosphorylated form of p27Kip1.
|
| Chopra S, Fernandez De Mattos S, Lam EW, Mann DJ.
|
| J Biol Chem 277(36):32413-6. 2002
|
| 57 | CDKN1B
|
| p27(Kip1) enhances myelin basic protein gene promoter activity.
|
| Miskimins R, Srinivasan R, Marin-Husstege M, Miskimins WK, Casaccia-Bonnefil P.
|
| J Neurosci Res 67(1):100-5. 2002
|
| 58 | CDKN1B
|
| Cloning and functional expression of a degradation-resistant novel isoform of p27Kip1.
|
| Hirano K, Hirano M, Zeng Y, Nishimura J, Hara K, Muta K, Nawata H, Kanaide H.
|
| Biochem J 353(Pt 1):51-57. 2001
|
| 59 | CDKN1B
|
| p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes.
|
| Boussiotis VA, Freeman GJ, Taylor PA, Berezovskaya A, Grass I, Blazar BR, Nadler LM.
|
| Nat Med 6(3):290-7. 2000
|
| 60 | CDKN1B
|
| Involvement of retinoblastoma protein in p27Kip1-induced apoptosis.
|
| Oh S, Kim TK, Hwang DS, Yim J.
|
| Cancer Lett 148(1):105-10. 2000
|
| 61 | CDKN1B
|
| Loss of p27(KIP1) expression predicts poor prognosis in patients with esophageal squamous cell carcinoma.
|
| Shamma A, Doki Y, Tsujinaka T, Shiozaki H, Inoue M, Yano M, Kawanishi K, Monden M.
|
| Oncology 58(2):152-8. 2000
|
| 62 | CDKN1B, COPS5, MIF
|
| Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1.
|
| Kleemann R, Hausser A, Geiger G, Mischke R, Burger-Kentischer A, Flieger O, Johannes FJ, Roger T, Calandra T, Kapurniotu A, Grell M, Finkelmeier D, Brunner H, Bernhagen J.
|
| Nature 408(6809):211-6. 2000
|
| 63 | CDKN1B, FOXO3, FOXO4
|
| AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1.
|
| Medema RH, Kops GJ, Bos JL, Burgering BM.
|
| Nature 404(6779):782-7. 2000
|
| 64 | CDKN1B, AP3S1P, ETV6, LRP6
|
| A physical, transcript, and deletion map of chromosome region 12p12. 3 flanked by ETV6 and CDKN1B: hypermethylation of the LRP6 CpG island in two leukemia patients with hemizygous del(12p).
|
| Baens M, et al.
|
| Genomics 56(1):40-50. 1999
|
| 65 | CDKN1B, ITGB1
|
| p27(kip1) acts as a downstream effector of and is coexpressed with the beta1C integrin in prostatic adenocarcinoma.
|
| Fornaro M, Tallini G, Zheng DQ, Flanagan WM, Manzotti M, Languino LR.
|
| J Clin Invest 103(3):321-9. 1999
|
| 66 | CDKN1B, TGFBR2
|
| Transforming growth factor beta receptors and p27kip in thyroid carcinoma.
|
| Muro-Cacho CA, et al.
|
| Arch Otolaryngol Head Neck Surg 125(1):76-81. 1999
|
| 67 | CDKN1B
|
| p27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers.
|
| Lloyd RV, et al.
|
| Am J Pathol 154(2):313-23. Review. 1999
|
| 68 | CDKN1B
|
| Low p27 expression correlates with poor prognosis for patients with oral tongue squamous cell carcinoma.
|
| Mineta H, et al.
|
| Cancer 85(5):1011-7. 1999
|
| 69 | CDKN1B
|
| Loss of p27Kip1 expression independently predicts poor prognosis for patients with resectable pancreatic adenocarcinoma.
|
| Lu CD, et al.
|
| Cancer 85(6):1250-60. 1999
|
| 70 | CDKN1B
|
| Two short sequences have positive effects on the human p27Kip1 gene transcription.
|
| Ito E, et al.
|
| Gene 228(1-2):93-100. 1999
|
| 71 | CDKN1B
|
| Regulatory role of p27kip1 in the mouse and human testis.
|
| Beumer TL, et al.
|
| Endocrinology 140(4):1834-40. 1999
|
| 72 | CDKN1B, CDKN1A
|
| Expression of p21(Cip1/Waf1/Sdi1) and p27(Kip1) cyclin-dependent kinase inhibitors during human hematopoiesis.
|
| Taniguchi T, et al.
|
| Blood 93(12):4167-78. 1999
|
| 73 | GPR19, CDKN1B
|
| Physical mapping of the G-protein coupled receptor 19 (GPR19) in the chromosome 12p12.3 region frequently rearranged in cancer cells.
|
| Montpetit A, et al.
|
| Hum Genet 105(1-2):162-4. 1999
|
| 74 | CDKN1B
|
| Loss of P27Kip1 expression correlates with tumor grade and with reduced disease-free survival in primary superficial bladder cancers.
|
| Sgambato A, et al.
|
| Cancer Res 59(13):3245-50 1999
|
| 75 | CCND3, CDKN1B
|
| Anomalous high p27/KIP1 expression in a subset of aggressive B-cell lymphomas is associated with cyclin D3 overexpression. p27/KIP1-cyclin D3 colocalization in tumor cells.
|
| Sanchez-Beato M, et al.
|
| Blood 94(2):765-72 1999
|
| 76 | CDKN1B
|
| Proteasome-dependent degradation of p27/kip1 in gliomas.
|
| Piva R, et al.
|
| J Neuropathol Exp Neurol 58(7):691-6 1999
|
| 77 | CDKN1B, SKP2
|
| SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27.
|
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| Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, p57KIP2, on chromosome 11p15.
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| Mice lacking p27Kip1 display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors.
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| 97 | CDKN1B, TSG12B
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| Loss of heterozygosity in the chromosomal region 12p12-13 is very common in childhood acute lymphoblastic leukemia and permits the precise localization of a tumor-suppressor gene distinct from p27KIP1.
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| p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene.
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| Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution.
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| 100 | CDK10, CDK9, CDK3, CDK6, CDKN1B
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| Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer.
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| Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies.
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| Cancer Res 55 : 2266-2269. 1995
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| Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation.
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| Cell 79 : 487-496. 1994
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| 105 | CDKN1B
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| Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals.
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| Cell 78 : 59-66. 1994
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| 106 | CDKN1B
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| p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity, is related to p21.
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