1 | CDK16, MRTFB, SRF
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| Genetic variation in MKL2 and decreased downstream PCTAIRE1 expression in extreme, fatal primary human microcephaly.
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| Ramos EI, Bien-Willner GA, Li J, Hughes AE, Giacalone J, Chasnoff S, Kulkarni S, Parmacek M, Cole FS, Druley TE.
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| Clin Genet 85(5):423-32. doi: 10.1111/cge.12197. Epub 2013 Jun 18. 2014
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2 | CCNY, CDK16
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| Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis.
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| Mikolcevic P, Sigl R, Rauch V, Hess MW, Pfaller K, Barisic M, Pelliniemi LJ, Boesl M, Geley S.
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| Mol Cell Biol 32(4):868-79. doi: 10.1128/MCB.06261-11. Epub 2011 Dec 19.
2012
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3 | BRSK2, CDK16
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| Brain-selective kinase 2 (BRSK2) phosphorylation on PCTAIRE1 negatively regulates glucose-stimulated insulin secretion in pancreatic β-cells.
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| Chen XY, Gu XT, Saiyin H, Wan B, Zhang YJ, Li J, Wang YL, Gao R, Wang YF, Dong WP, Najjar SM, Zhang CY, Ding HF, Liu JO, Yu L.
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| J Biol Chem 287(36):30368-75. doi: 10.1074/jbc.M112.375618. Epub 2012 Jul 13.
2012
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4 | CCNY, CDK16
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| Orphan kinases turn eccentric: a new class of cyclin Y-activated, membrane-targeted CDKs.
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| Mikolcevic P, Rainer J, Geley S.
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| Cell Cycle 11(20):3758-68. doi: 10.4161/cc.21592. Epub 2012 Aug 16. Review.
2012
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5 | CDK16, CDK5
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| Cyclin-dependent kinase 5-dependent phosphorylation of Pctaire1 regulates dendrite development.
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| Fu WY, Cheng K, Fu AK, Ip NY.
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| Neuroscience 180:353-9. doi: 10.1016/j.neuroscience.2011.02.024. Epub 2011 Feb 16.
2011
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6 | CDK12, CDK13, CDK16, CDK17, CDK20
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| Cyclin-dependent kinases: a family portrait.
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| Malumbres M, Harlow E, Hunt T, Hunter T, Lahti JM, Manning G, Morgan DO, Tsai LH, Wolgemuth DJ.
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| Nat Cell Biol 11(11):1275-6. No abstract available. 2009
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7 | CDK16
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| Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein: implications in the regulation of its hexamerization and exocytosis.
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| Liu Y, Cheng K, Gong K, Fu AK, Ip NY.
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| J Biol Chem 281(15):9852-8. Epub 2006 Feb 6.
2006
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8 | CDK16
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| Regulation of the CDK-related protein kinase PCTAIRE-1 and its possible role in neurite outgrowth in Neuro-2A cells.
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| Graeser R, Gannon J, Poon RY, Dubois T, Aitken A, Hunt T.
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| J Cell Sci 115(Pt 17):3479-90. 2002
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9 | CDK16, CDK5
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| Pctaire1 interacts with p35 and is a novel substrate for Cdk5/p35.
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| Cheng K, Li Z, Fu WY, Wang JH, Fu AK, Ip NY.
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| J Biol Chem 277(35):31988-93. Epub 2002 Jun 25. 2002
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10 | CDK16, CSNB1A, CSNB2A, RP2, USP11
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| UHX1 and PCTK1 : precise characterisation and localisation within a gene-rich region in Xp11.23 and evaluation as candidate genes for retinal diseases mapped to Xp21.1-p11.2.
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| Brandau O, et al.
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| Eur J Hum Genet 6 : 459-466. 1998
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11 | CDK16, PCTK1IR
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| Characterization of brain PCTAIRE-1 kinase immunoreactivity and its interactions with p11 and 14-3-3 proteins.
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| Le Bouffant F, et al.
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| Eur J Biochem 257 : 112-120. 1998
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12 | CDK16, UBA1
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| X inactivation analysis and DNA methylation studies of the ubiquitin activating enzyme E1 and PCTAIRE-1 genes in human and mouse.
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| Carrel L, Clemson CM, Dunn JM, Miller AP, Hunt PA, Lawrence JB, Willard HF.
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| Hum Mol Genet 5(3):391-401. 1996
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13 | CDK16, UBA1
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| Physical linkage of the cdc2-related gene (PCTK1) and the ubiquitin-activating enzyme E1 gene (UBE1) on human Xp11.3.
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| Knight JC, Renwick PJ, Downing JR, Okuda T.
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| Cytogenet Cell Genet 71(2):155-7. 1995
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14 | CDK16, PCTK3
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| Cloning of genomic loci and chromosomal localization of the human PCTAIRE-1 and -3 protein kinase genes.
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| Okuda T, et al.
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| Genomics 21 : 217-221. 1994
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15 | CDK16, CDK17, CDKL1, CDKL3, PCTK3
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| A family of human cdc2-related protein kinases.
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| Meyerson M, Enders GH, Wu CL, Su LK, Gorka C, Nelson C, Harlow E, Tsai LH.
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| EMBO J 11(8):2909-17. 1992
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