| 1 | CDK11A, GADD45A, GADD45G, SPDEF
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| GADD45α and γ interaction with CDK11p58 regulates SPDEF protein stability and SPDEF-mediated effects on cancer cell migration.
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| Tamura RE, Paccez JD, Duncan KC, Morale MG, Simabuco FM, Dillon S, Correa RG, Gu X, Libermann TA, Zerbini LF.
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| Oncotarget 7(12):13865-79. doi: 10.18632/oncotarget.7355.
2016
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| 2 | CDK11A, ITGB3
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| CDK11p58 inhibits ERα-positive breast cancer invasion by targeting integrin β3 via the repression of ERα signaling.
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| Chi Y, Huang S, Wang L, Zhou R, Wang L, Xiao X, Li D, Cai Y, Zhou X, Wu J.
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| BMC Cancer 14:577. doi: 10.1186/1471-2407-14-577.
2014
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| 3 | CDK11A, CHEK2
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| CHK2 kinase promotes pre-mRNA splicing via phosphorylating CDK11(p110).
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| Choi HH, Choi HK, Jung SY, Hyle J, Kim BJ, Yoon K, Cho EJ, Youn HD, Lahti JM, Qin J, Kim ST.
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| Oncogene 33(1):108-15. doi: 10.1038/onc.2012.535. Epub 2012 Nov 26.
2014
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| 4 | CDK11A, MED27, MED4
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| Cdk11-cyclinL controls the assembly of the RNA polymerase II mediator complex
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| Drogat J, Migeot V, Mommaerts E, Mullier C, Dieu M, van Bakel H, Hermand D.
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| Cell Rep. Nov 29;2(5):1068-76. doi: 10.1016/j.celrep.2012.09.027. Epub 2012 Nov 1. 2012
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| 5 | CCND3, CDK11A
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| Cyclin D3/CDK11(p58) complex involved in Schwann cells proliferation repression caused by lipopolysaccharide.
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| Duan Y, He X, Yang H, Ji Y, Tao T, Chen J, Hu L, Zhang F, Li X, Wang H, Shen A, Lu X.
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| Inflammation 33(3):189-99.
2010
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| 6 | CDK11A, CDK11B, PAK1
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| CDK11p58 phosphorylation of PAK1 Ser174 promotes DLC2 binding and roles on cell cycle progression.
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| Kong X, Gan H, Hao Y, Cheng C, Jiang J, Hong Y, Yang J, Zhu H, Chi Y, Yun X, Gu J.
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| J Biochem 146(3):417-27. Epub 2009 Jun 11.PMID: 19520772 2009
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| 7 | CDK11A, CDK11B
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| Repression of estrogen receptor alpha by CDK11p58 through promoting its ubiquitin-proteasome degradation.
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| Wang Y, Zong H, Chi Y, Hong Y, Yang Y, Zou W, Yun X, Gu J.
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| J Biochem 145(3):331-43. Epub 2009 Jan 2.PMID: 19122208 2009
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| 8 | CCNL1, CCNL2, CDK11A, CDK11B
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| Characterization of cyclin L1 and L2 interactions with CDK11 and splicing factors: Influence of cyclin L isoforms on splice site selection.
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| Loyer P, Trembley JH, Grenet JA, Busson A, Corlu A, Zhao W, Kocak M, Kidd VJ, Lahti JM.
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| J Biol Chem [Epub ahead of print] 2008
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| 9 | CDK11A
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| Genetic variations of the CDC2L2 gene are associated with type 2 diabetes in a Han Chinese cohort.
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| Li Y, Wu G, Zuo J, Gao J, Chang Y, Fang FD.
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| Diabetes Metab Res Rev 23(6):455-61.PMID: 17177267 2007
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| 10 | CDK11A
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| CDK11(p58) is required for the maintenance of sister chromatid cohesion.
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| Hu D, Valentine M, Kidd VJ, Lahti JM.
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| J Cell Sci 120(Pt 14):2424-34.PMID: 17606997 2007
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| 11 | CDK11A
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| The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation.
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| Petretti C, Savoian M, Montembault E, Glover DM, Prigent C, Giet R.
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| EMBO Rep 7(4):418-24. Epub 2006 Feb 3.PMID: 16462731 2006
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| 12 | CDK11A, CDK11B
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| The cyclin-dependent kinase 11 interacts with 14-3-3 proteins.
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| Feng Y, Qi W, Martinez J, Nelson MA.
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| Biochem Biophys Res Commun 331(4):1503-9. 2005
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| 13 | CDK11A
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| Regulation of the cell-cycle-dependent internal ribosome entry site of the PITSLRE protein kinase: roles of Unr (upstream of N-ras) protein and phosphorylated translation initiation factor eIF-2alpha.
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| Tinton SA, Schepens B, Bruynooghe Y, Beyaert R, Cornelis S.
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| Biochem J 385(Pt 1):155-63. 2005
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| 14 | CDK11A, CDK11B
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| Failure to proliferate and mitotic arrest of CDK11(p110/p58)-null mutant mice at the blastocyst stage of embryonic cell development.
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| Li T, Inoue A, Lahti JM, Kidd VJ.
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| Mol Cell Biol 24(8):3188-97. 2004
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| 15 | CDK11A
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| Identification and characterization of the human Cdc2l2 gene promoter.
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| Feng Y, Goulet AC, Nelson MA.
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| Gene 330:75-84. 2004
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| 16 | CDK11A, CDK11B
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| Identification and characterization of a novel cell cycle-regulated internal ribosome entry site.
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| Cornelis S, Bruynooghe Y, Denecker G, Van Huffel S, Tinton S, Beyaert R.
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| Mol Cell 5(4):597-605. 2000
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| 17 | CDK11A, CDK11B, MMP23A, MMP23B
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| Duplication of a genomic region containing the Cdc2L1-2 and MMP21-22 genes on human chromosome 1p36.3 and their linkage to D1Z2.
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| Gururajan R, Lahti JM, Grenet J, Easton J, Gruber I, Ambros PF, Kidd VJ.
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| Genome Res 8(9):929-39. 1998
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| 18 | CDK11A, CDK11B
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| Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP32/CASP-3 during apoptosis induced by tumor necrosis factor.
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| Beyaert R, Kidd VJ, Cornelis S, Van de Craen M, Denecker G, Lahti JM, Gururajan R, Vandenabeele P, Fiers W.
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| J Biol Chem 272(18):11694-7. 1997
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| 19 | CDK11A, CDK11B, NBL, TSG1A, TSG1C
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| A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3.
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| White PS, et al.
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| Proc Natl Acad Sci U S A 92 : 5520-5524. 1995
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| 20 | CDK11A, CDK11B
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| Molecular cloning and expression of alternatively spliced PITSLRE protein kinase isoforms.
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| Xiang J, Lahti JM, Grenet J, Easton J, Kidd VJ.
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| J Biol Chem 269(22):15786-94. 1994
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| 21 | CDC2LR, CDK11A, CDK11B
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| Localization of the expressed human p58 protein kinase chromosomal gene to chromosome 1p36 and a hihgly related sequence to chromosome 15.
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| Eipers PG, et al.
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| Genomics 11 : 621-629. 1991
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| 22 | CDK11A, CDK11B
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| Increased expression of a 58-kDa protein kinase leads to changes in the CHO cell cycle.
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| Bunnell BA, Heath LS, Adams DE, Lahti JM, Kidd VJ.
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| Proc Natl Acad Sci U S A 87(19):7467-71. 1990
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