| 1 | CDH1, CDH3, CTNND1, GNRH1
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| Cadherin switching and activation of p120 catenin signaling are mediators of gonadotropin-releasing hormone to promote tumor cell migration and invasion in ovarian cancer.
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| Cheung LW, Leung PC, Wong AS.
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| Oncogene 29(16):2427-40. Epub 2010 Feb 1.
2010
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| 2 | CDH3, HJMD
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| Splice site mutations in the P-cadherin gene underlie hypotrichosis with juvenile macular dystrophy.
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| Shimomura Y, Wajid M, Kurban M, Christiano AM.
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| Dermatology 220(3):208-12. Epub 2010 Mar 5.
2010
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| 3 | CDH1, CDH3
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| Extracellular cleavage and shedding of P-cadherin: a mechanism underlying the invasive behaviour of breast cancer cells.
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| Ribeiro AS, Albergaria A, Sousa B, Correia AL, Bracke M, Seruca R, Schmitt FC, Paredes J.
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| Oncogene 29(3):392-402. Epub 2009 Nov 9.
2010
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| 4 | CDH1, CDH3, GH1, ZEB2
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| Growth hormone (GH)-dependent expression of a natural antisense transcript induces zinc finger E-box-binding homeobox 2 (ZEB2) in the glomerular podocyte: a novel action of gh with implications for the pathogenesis of diabetic nephropathy.
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| Kumar PA, Kotlyarevska K, Dejkhmaron P, Reddy GR, Lu C, Bhojani MS, Menon RK.
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| J Biol Chem 285(41):31148-56. Epub 2010 Aug 3.
2010
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| 5 | CDH3
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| Demethylation of the CDH3 gene is frequently detected in advanced colorectal cancer.
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| Hibi K, Goto T, Mizukami H, Kitamura YH, Sakuraba K, Sakata M, Saito M, Ishibashi K, Kigawa G, Nemoto H, Sanada Y.
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| Anticancer Res 29(6):2215-7.
2009
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| 6 | CDH3, TP63
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| P-cadherin is a p63 target gene with a crucial role in the developing human limb bud and hair follicle.
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| Shimomura Y, Wajid M, Shapiro L, Christiano AM.
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| Development 135(4):743-53. Epub 2008 Jan 16.PMID: 18199584 2008
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| 7 | CDH3
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| Identification of a novel tumor-associated antigen, cadherin 3/P-cadherin, as a possible target for immunotherapy of pancreatic, gastric, and colorectal cancers.
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| Imai K, Hirata S, Irie A, Senju S, Ikuta Y, Yokomine K, Harao M, Inoue M, Tsunoda T, Nakatsuru S, Nakagawa H, Nakamura Y, Baba H, Nishimura Y.
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| Clin Cancer Res 14(20):6487-95.
2008
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| 8 | CDH3
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| Ectopic expression of P-cadherin correlates with promoter hypomethylation early in colorectal carcinogenesis and enhanced intestinal crypt fission in vivo.
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| Milicic A, Harrison LA, Goodlad RA, Hardy RG, Nicholson AM, Presz M, Sieber O, Santander S, Pringle JH, Mandir N, East P, Obszynska J, Sanders S, Piazuelo E, Shaw J, Harrison R, Tomlinson IP, McDonald SA, Wright NA, Jankowski JA.
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| Cancer Res 68(19):7760-8.
2008
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| 9 | CDH3
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| Relationship of P-cadherin expression to basal phenotype of breast carcinoma.
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| Potemski P, Kusińska R, Kubiak R, Piekarski JH, Płuciennik E, Bednarek AK, Kordek R.
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| Pol J Pathol 58(3):183-8.
2007
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| 10 | CDH3
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| beta-Catenin regulates P-cadherin expression in mammary basal epithelial cells.
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| Faraldo MM, Teulière J, Deugnier MA, Birchmeier W, Huelsken J, Thiery JP, Cano A, Glukhova MA.
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| FEBS Lett 581(5):831-6. Epub 2007 Feb 2.
2007
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| 11 | CDH3
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| Functional implication of truncated P-cadherin expression in malignant melanoma.
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| Bauer R, Bosserhoff AK.
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| Exp Mol Pathol 81(3):224-30. Epub 2006 Aug 17.
2006
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| 12 | CDH3, EEM
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| Distinct CDH3 mutations cause ectodermal dysplasia, ectrodactyly, macular dystrophy (EEM syndrome).
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| Kjaer KW, Hansen L, Schwabe GC, Marques-de-Faria AP, Eiberg H, Mundlos S, Tommerup N, Rosenberg T.
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| J Med Genet 42(4):292-8. 2005
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| 13 | CDH3
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| P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation.
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| Paredes J, Albergaria A, Oliveira JT, Jeronimo C, Milanezi F, Schmitt FC.
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| Clin Cancer Res 11(16):5869-77. 2005
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| 14 | CDH3
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| A secreted form of P-cadherin is expressed in malignant melanoma.
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| Bauer R, Hein R, Bosserhoff AK.
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| Exp Cell Res 305(2):418-26. 2005
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| 15 | CDH3, HJMD
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| Molecular basis of hypotrichosis with juvenile macular dystrophy in two siblings.
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| Indelman M, Leibu R, Jammal A, Bergman R, Sprecher E.
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| Br J Dermatol 153(3):635-8. 2005
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| 16 | CDH3, DFNB12, USH1D
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| CDH23 mutation and phenotype heterogeneity: a profile of 107 diverse families with Usher syndrome and nonsyndromic deafness.
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| Astuto LM, Bork JM, Weston MD, Askew JW, Fields RR, Orten DJ, Ohliger SJ, Riazuddin S, Morell RJ, Khan S, Riazuddin S, Kremer H, van Hauwe P, Moller CG, Cremers CW, Ayuso C, Heckenlively JR, Rohrschneider K, Spandau U, Greenberg J, Ramesar R, Reardon W, Bitoun P, Millan J, Legge R, Friedman TB, Kimberling WJ.
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| Am J Hum Genet 71(2):262-75. 2002
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| 17 | CDH3, HJMD
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| A missense mutation in CDH3, encoding P-cadherin, causes hypotrichosis with juvenile macular dystrophy.
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| Indelman M, Bergman R, Lurie R, Richard G, Miller B, Petronius D, Ciubutaro D, Leibu R, Sprecher E.
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| J Invest Dermatol 119(5):1210-3. 2002
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| 18 | CDH3, HJMD
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| Hypotrichosis with juvenile macular dystrophy is caused by a mutation in CDH3, encoding P-cadherin.
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| Sprecher E, Bergman R, Richard G, Lurie R, Shalev S, Petronius D, Shalata A, Anbinder Y, Leibu R, Perlman I, Cohen N, Szargel R.
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| Nat Genet 29(2):134-6. 2001
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| 19 | CDH1, CDH10, CDH11, CDH12, CDH12P, CDH13, CDH15, CDH16, CDH17, CDH18, CDH19, CDH2, CDH20, CDH23, CDH3, CDH4, CDH5, CDH6, CDH7, CDH8, CDH9, PCDH11Y, PCDHA@, PCDHA1, PCDHA10, PCDHA11, PCDHA12, PCDHA13, PCDHA14, PCDHA2, PCDHA3, PCDHA4, PCDHA5, PCDHA6, PCDHA7, PCDHA8, PCDHA9, PCDHACT, PCDHB1, PCDHB10, PCDHB11, PCDHB12, PCDHB13, PCDHB14, PCDHB15, PCDHB16, PCDHB2, PCDHB3, PCDHB4, PCDHB5, PCDHB6, PCDHB7, PCDHB8, PCDHB9, PCDHAC1, PCDHAC2, PCDHGA1, PCDHGA10, PCDHGA11, PCDHGA12, PCDHGA2, PCDHGA3, PCDHGA4, PCDHGA5, PCDHGA6, PCDHGA7, PCDHGA8, PCDHGA9, PCDHGB1, PCDHGB2, PCDHGB3, PCDHGB4, PCDHGB5, PCDHGB6, PCDHGB7, PCDHGC3, PCDHGC4, PCDHGC5, PCDHGCT
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| Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.
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| Nollet F, Kools P, van Roy F.
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| J Mol Biol 299(3):551-72. Review. 2000
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| 20 | CDH3, CDH5, CDH6, CDH7, CDH8, CDH11, CDH13, CDH15, CDH17
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| Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity.
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| Kremmidiotis G, et al.
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| Genomics 49 : 467-471. 1998
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| 21 | CDH3
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| Sequential changes in cadherin-catenin expression associated with the progression and heterogeneity of primary oesophageal squamous carcinoma.
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| Sanders DS, et al.
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| Int J Cancer 79 : 573-579. 1998
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