| 1 | CDH1, METTL3, ZMYM1
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| METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancer.
|
| Yue B, Song C, Yang L, Cui R, Cheng X, Zhang Z, Zhao G.
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| Mol Cancer 18(1):142. doi: 10.1186/s12943-019-1065-4.
2019
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| 2 | CDH1, S100P
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| S100P is a molecular determinant of E-cadherin function in gastric cancer.
|
| Carneiro P, Moreira AM, Figueiredo J, Barros R, Oliveira P, Fernandes MS, Ferro A, Almeida R, Oliveira C, Carneiro F, Schmitt F, Paredes J, Velho S, Seruca R.
|
| Cell Commun Signal 17(1):155. doi: 10.1186/s12964-019-0465-9.
2019
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| 3 | CDH1, HSPD1
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| HSPD1 repressed E-cadherin expression to promote cell invasion and migration for poor prognosis in oral squamous cell carcinoma.
|
| Kang BH, Shu CW, Chao JK, Lee CH, Fu TY, Liou HH, Ger LP, Liu PF.
|
| Sci Rep 9(1):8932. doi: 10.1038/s41598-019-45489-1. Erratum in: Sci Rep. 2020 Jan 30;10(1):1829.
2019
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| 4 | AKT1, CDH1, DSC3
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| Desmocollin 3 has a tumor suppressive activity through inhibition of AKT pathway in colorectal cancer.
|
| Cui T, Yang L, Ma Y, Petersen I, Chen Y.
|
| Exp Cell Res 378(2):124-130. doi: 10.1016/j.yexcr.2019.03.015. Epub 2019 Mar 8.
2019
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| 5 | ANXA1, CDH1, SNAI1
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| Effect of Annexin A1 gene on the proliferation and invasion of esophageal squamous cell carcinoma cells and its regulatory mechanisms.
|
| Han G, Lu K, Huang J, Ye J, Dai S, Ye Y, Zhang L.
|
| Int J Mol Med 39(2):357-363. doi: 10.3892/ijmm.2016.2840. Epub 2016 Dec 28.
2017
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| 6 | CDH1, GRHL3
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| Grhl3 induces human epithelial tumor cell migration and invasion via downregulation of E-cadherin.
|
| Zhao P, Guo S, Tu Z, Di L, Zha X, Zhou H, Zhang X.
|
| Acta Biochim Biophys Sin (Shanghai) 48(3):266-74. doi: 10.1093/abbs/gmw001. Epub 2016 Feb 1.
2016
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| 7 | AHNAK, CDH1
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| AHNAK is downregulated in melanoma, predicts poor outcome, and may be required for the expression of functional cadherin-1.
|
| Sheppard HM, Feisst V, Chen J, Print C, Dunbar PR.
|
| Melanoma Res 26(2):108-16. doi: 10.1097/CMR.0000000000000228.
2016
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| 8 | CDH1, MRCPH, MRDO, PLS3
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| Exome sequencing-based identification of mutations in non-syndromic genes among individuals with apparently syndromic features.
|
| Nishi E, Masuda K, Arakawa M, Kawame H, Kosho T, Kitahara M, Kubota N, Hidaka E, Katoh Y, Shirahige K, Izumi K.
|
| Am J Med Genet A 170(11):2889-2894. doi: 10.1002/ajmg.a.37826.
2016
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| 9 | CDH1, DDB1, XPC
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| TGF-β signaling links E-cadherin loss to suppression of nucleotide excision repair.
|
| Qiang L, Shah P, Barcellos-Hoff MH, He YY.
|
| Oncogene. Jun 23;35(25):3293-302. doi: 10.1038/onc.2015.390. Epub 2015 Oct 19. 2016
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| 10 | CDH1, CTNNB1, PROM1
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| CD133 expression correlates with membrane beta-catenin and E-cadherin loss from human hair follicle placodes during morphogenesis.
|
| Gay DL, Yang CC, Plikus MV, Ito M, Rivera C, Treffeisen E, Doherty L, Spata M, Millar SE, Cotsarelis G.
|
| J Invest Dermatol 135(1):45-55. doi: 10.1038/jid.2014.292. Epub 2014 Jul 10.
2015
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| 11 | ADAM12, CDH1
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| ADAM12-directed ectodomain shedding of E-cadherin potentiates trophoblast fusion.
|
| Aghababaei M, Hogg K, Perdu S, Robinson WP, Beristain AG.
|
| Cell Death Differ 22(12):1970-84. doi: 10.1038/cdd.2015.44.
2015
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| 12 | CDH1, NOSTRIN, TRIP10
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| Cooperative functions of the two F-BAR proteins Cip4 and Nostrin in the regulation of E-cadherin in epithelial morphogenesis.
|
| Zobel T, Brinkmann K, Koch N, Schneider K, Seemann E, Fleige A, Qualmann B, Kessels MM, Bogdan S
|
| J Cell Sci. Feb 1;128(3):499-515. doi: 10.1242/jcs.155929. Erratum in: J Cell Sci. 2015 Apr 1;128(7):1453 2015
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| 13 | CDH1, LRP12
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| A gene panel, including LRP12, is frequently hypermethylated in major types of B-cell lymphoma
|
| Bethge N, Honne H, Andresen K, Hilden V, Trøen G, Liestøl K, Holte H, Delabie J, Lind GE, Smeland EB.
|
| PLoS One. Sep 16;9(9):e104249. doi: 10.1371/journal.pone.0104249. 2014
|
| 14 | CDC20, CDH1, MAD2L2
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| Sequestration of CDH1 by MAD2L2 prevents premature APC/C activation prior to anaphase onset.
|
| Listovsky T, Sale JE.
|
| J Cell Biol 203(1):87-100. doi: 10.1083/jcb.201302060. Epub 2013 Oct 7.
2013
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| 15 | CDH1, DSG2, SNAI1
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| The transcription factor Snail enhanced the degradation of E-cadherin and desmoglein 2 in oral squamous cell carcinoma cells.
|
| Kume K, Haraguchi M, Hijioka H, Ishida T, Miyawaki A, Nakamura N, Ozawa M.
|
| Biochem Biophys Res Commun 430(3):889-94. doi: 10.1016/j.bbrc.2012.12.060. Epub 2012 Dec 20.
2013
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| 16 | CDH1, KLF4, ZEB2
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| Interplay between KLF4 and ZEB2/SIP1 in the regulation of E-cadherin expression.
|
| Koopmansch B, Berx G, Foidart JM, Gilles C, Winkler R.
|
| Biochem Biophys Res Commun 431(4):652-7. doi: 10.1016/j.bbrc.2013.01.070. Epub 2013 Jan 29.
2013
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| 17 | CDH1, STAT3, ZEB1
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| Roles of STAT3 and ZEB1 proteins in E-cadherin down-regulation and human colorectal cancer epithelial-mesenchymal transition.
|
| Xiong H, Hong J, Du W, Lin YW, Ren LL, Wang YC, Su WY, Wang JL, Cui Y, Wang ZH, Fang JY.
|
| J Biol Chem 287(8):5819-32. doi: 10.1074/jbc.M111.295964. Epub 2011 Dec 28.
2012
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| 18 | CDH1, GJA1, GJB2, TCF12
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| TCF12 protein functions as transcriptional repressor of E-cadherin, and its overexpression is correlated with metastasis of colorectal cancer.
|
| Lee CC, Chen WS, Chen CC, Chen LL, Lin YS, Fan CS, Huang TS.
|
| J Biol Chem 287(4):2798-809. doi: 10.1074/jbc.M111.258947. Epub 2011 Nov 30.
2012
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| 19 | CDH1, RACK1
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| Rack1 promotes epithelial cell-cell adhesion by regulating E-cadherin endocytosis.
|
| Swaminathan G, Cartwright CA.
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| Oncogene 31(3):376-89. doi: 10.1038/onc.2011.242. Epub 2011 Jun 20. 2012
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| 20 | CDH1, CTNND1
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| Competitive regulation of E-cadherin juxtamembrane domain degradation by p120-catenin binding and Hakai-mediated ubiquitination.
|
| Hartsock A, Nelson WJ.
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| PLoS One 7(5):e37476. doi: 10.1371/journal.pone.0037476. Epub 2012 May 31.
2012
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| 21 | CDH1, SIK1
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| Salt-inducible kinase 1 regulates E-cadherin expression and intercellular junction stability.
|
| Eneling K, Brion L, Pinto V, Pinho MJ, Sznajder JI, Mochizuki N, Emoto K, Soares-da-Silva P, Bertorello AM.
|
| FASEB J 26(8):3230-9. doi: 10.1096/fj.12-205609. Epub 2012 Apr 20.
2012
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| 22 | CDH1, GAB2, ZEB1
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| Gab2 regulates the migratory behaviors and E-cadherin expression via activation of the PI3K pathway in ovarian cancer cells.
|
| Wang Y, Sheng Q, Spillman MA, Behbakht K, Gu H.
|
| Oncogene 31(20):2512-20. doi: 10.1038/onc.2011.435. Epub 2011 Sep 26.
2012
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| 23 | AKT2, CDH1, SNAI1
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| Akt2 interacts with Snail1 in the E-cadherin promoter.
|
| Villagrasa P, Díaz VM, Viñas-Castells R, Peiró S, Del Valle-Pérez B, Dave N, Rodríguez-Asiain A, Casal JI, Lizcano JM, Duñach M, García de Herreros A.
|
| Oncogene 31(36):4022-33. doi: 10.1038/onc.2011.562.
2012
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| 24 | ATR, CDC6, CDH1
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| Hypoxic activation of ATR and the suppression of the initiation of DNA replication through cdc6 degradation.
|
| Martin L, Rainey M, Santocanale C, Gardner LB.
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| Oncogene 31(36):4076-84. doi: 10.1038/onc.2011.585.
2012
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| 25 | CDH1, RHOA, SMURF1
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| The E3 ligase Cdh1-anaphase promoting complex operates upstream of the E3 ligase Smurf1 in the control of axon growth.
|
| Kannan M, Lee SJ, Schwedhelm-Domeyer N, Stegmüller J.
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| Development 139(19):3600-12. doi: 10.1242/dev.081786.
2012
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| 26 | CDH1, ETV5, ZEB1
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| ETV5 cooperates with LPP as a sensor of extracellular signals and promotes EMT in endometrial carcinomas.
|
| Colas E, Muinelo-Romay L, Alonso-Alconada L, Llaurado M, Monge M, Barbazan J, Gonzalez M, Schoumacher M, Pedrola N, Ertekin T, Devis L, Ruiz A, Castellvi J, Doll A, Gil-Moreno A, Vazquez-Levin M, Lapyckyj L, Lopez-Lopez R, Robine S, Friederich E, Castro M, Reventos J, Vignjevic D, Abal M.
|
| Oncogene 31(45):4778-88. doi: 10.1038/onc.2011.632. Epub 2012 Jan 23.
2012
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| 27 | ACTR2, ACTR3, CDH1, WASF2
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| A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens.
|
| Verma S, Han SP, Michael M, Gomez GA, Yang Z, Teasdale RD, Ratheesh A, Kovacs EM, Ali RG, Yap AS.
|
| Mol Biol Cell 23(23):4601-10. doi: 10.1091/mbc.E12-08-0574. Epub 2012 Oct 10.
2012
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| 28 | CDH1, CDK2, USP37
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| Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry.
|
| Huang X, Summers MK, Pham V, Lill JR, Liu J, Lee G, Kirkpatrick DS, Jackson PK, Fang G, Dixit VM.
|
| Mol Cell 42(4):511-23.
2011
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| 29 | ADAM10, CDH1, EPHB1, EPHB3
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| Cleavage of E-cadherin by ADAM10 mediates epithelial cell sorting downstream of EphB signalling.
|
| Solanas G, Cortina C, Sevillano M, Batlle E.
|
| Nat Cell Biol 13(9):1100-7. doi: 10.1038/ncb2298.
2011
|
| 30 | CDH1, MAGED1, TBX2
|
| A pathway for the control of anoikis sensitivity by E-cadherin and epithelial-to-mesenchymal transition.
|
| Kumar S, Park SH, Cieply B, Schupp J, Killiam E, Zhang F, Rimm DL, Frisch SM.
|
| Mol Cell Biol 31(19):4036-51. Epub 2011 Jul 11.
2011
|
| 31 | CDH1
|
| E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components.
|
| Kim NG, Koh E, Chen X, Gumbiner BM.
|
| Proc Natl Acad Sci U S A 108(29):11930-5. Epub 2011 Jul 5.
2011
|
| 32 | CDH1
|
| E-cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming.
|
| Redmer T, Diecke S, Grigoryan T, Quiroga-Negreira A, Birchmeier W, Besser D.
|
| EMBO Rep 12(7):720-6. doi: 10.1038/embor.2011.88.
2011
|
| 33 | CDH1, MMP20
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| MMP20 cleaves E-cadherin and influences ameloblast development.
|
| Bartlett JD, Yamakoshi Y, Simmer JP, Nanci A, Smith CE.
|
| Cells Tissues Organs 194(2-4):222-6. Epub 2011 Apr 28.
2011
|
| 34 | CDH1
|
| Down-regulation of epithelial cadherin is required to initiate metastatic outgrowth of breast cancer.
|
| Wendt MK, Taylor MA, Schiemann BJ, Schiemann WP.
|
| Mol Biol Cell 22(14):2423-35. Epub 2011 May 25.
2011
|
| 35 | CDH1, SMURF1
|
| Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1.
|
| Wan L, Zou W, Gao D, Inuzuka H, Fukushima H, Berg AH, Drapp R, Shaik S, Hu D, Lester C, Eguren M, Malumbres M, Glimcher LH, Wei W.
|
| Mol Cell 44(5):721-33. doi: 10.1016/j.molcel.2011.09.024.
2011
|
| 36 | CDH1, FOXO3, IRS2
|
| Insulin receptor substrate 2 and FoxO3a signalling are involved in E-cadherin expression and transforming growth factor-β1-induced repression in kidney epithelial cells.
|
| Carew RM, Browne MB, Hickey FB, Brazil DP.
|
| FEBS J 278(18):3370-80. doi: 10.1111/j.1742-4658.2011.08261.x. Epub 2011 Aug 16.
2011
|
| 37 | CDC6, CDH1
|
| Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins.
|
| Sideridou M, Zakopoulou R, Evangelou K, Liontos M, Kotsinas A, Rampakakis E, Gagos S, Kahata K, Grabusic K, Gkouskou K, Trougakos IP, Kolettas E, Georgakilas AG, Volarevic S, Eliopoulos AG, Zannis-Hadjopoulos M, Moustakas A, Gorgoulis VG.
|
| J Cell Biol 195(7):1123-40. doi: 10.1083/jcb.201108121.
2011
|
| 38 | CDH1, CDH6
|
| Distinct roles of cadherin-6 and E-cadherin in tubulogenesis and lumen formation.
|
| Jia L, Liu F, Hansen SH, Ter Beest MB, Zegers MM.
|
| Mol Biol Cell 22(12):2031-41. doi: 10.1091/mbc.E11-01-0038.
2011
|
| 39 | CDH1, CDH3, CTNND1, GNRH1
|
| Cadherin switching and activation of p120 catenin signaling are mediators of gonadotropin-releasing hormone to promote tumor cell migration and invasion in ovarian cancer.
|
| Cheung LW, Leung PC, Wong AS.
|
| Oncogene 29(16):2427-40. Epub 2010 Feb 1.
2010
|
| 40 | CDH1, KLF4
|
| Kruppel-like factor 4 inhibits epithelial-to-mesenchymal transition through regulation of E-cadherin gene expression.
|
| Yori JL, Johnson E, Zhou G, Jain MK, Keri RA.
|
| J Biol Chem 285(22):16854-63. Epub 2010 Mar 31.
2010
|
| 41 | CDH1, SMARCA4, ZEB1
|
| ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1.
|
| Sánchez-Tilló E, Lázaro A, Torrent R, Cuatrecasas M, Vaquero EC, Castells A, Engel P, Postigo A.
|
| Oncogene 29(24):3490-500. Epub 2010 Apr 26. 2010
|
| 42 | CDH1, DNMT3A, EHMT1, MPHOSPH8, SETDB2
|
| Methyl-H3K9-binding protein MPP8 mediates E-cadherin gene silencing and promotes tumour cell motility and invasion.
|
| Kokura K, Sun L, Bedford MT, Fang J.
|
| EMBO J 29(21):3673-87. Epub 2010 Sep 24.PMID: 20871592 2010
|
| 43 | CDH1, CDH3
|
| Extracellular cleavage and shedding of P-cadherin: a mechanism underlying the invasive behaviour of breast cancer cells.
|
| Ribeiro AS, Albergaria A, Sousa B, Correia AL, Bracke M, Seruca R, Schmitt FC, Paredes J.
|
| Oncogene 29(3):392-402. Epub 2009 Nov 9.
2010
|
| 44 | CDH1, CDH3, GH1, ZEB2
|
| Growth hormone (GH)-dependent expression of a natural antisense transcript induces zinc finger E-box-binding homeobox 2 (ZEB2) in the glomerular podocyte: a novel action of gh with implications for the pathogenesis of diabetic nephropathy.
|
| Kumar PA, Kotlyarevska K, Dejkhmaron P, Reddy GR, Lu C, Bhojani MS, Menon RK.
|
| J Biol Chem 285(41):31148-56. Epub 2010 Aug 3.
2010
|
| 45 | CDH1, PAK1
|
| Pak1 control of E-cadherin endocytosis regulates salivary gland lumen size and shape.
|
| Pirraglia C, Walters J, Myat MM.
|
| Development 137(24):4177-89. Epub 2010 Nov 10.
2010
|
| 46 | CDH1, DDB1
|
| Damaged DNA-binding protein 1 (DDB1) interacts with Cdh1 and modulates the function of APC/CCdh1.
|
| Lv XB, Xie F, Hu K, Wu Y, Cao LL, Han X, Sang Y, Zeng YX, Kang T.
|
| J Biol Chem 285(24):18234-40. Epub 2010 Apr 15.
2010
|
| 47 | CDH1, HDGC
|
| Germline CDH1 deletions in hereditary diffuse gastric cancer families.
|
| Oliveira C, Senz J, Kaurah P, Pinheiro H, Sanges R, Haegert A, Corso G, Schouten J, Fitzgerald R, Vogelsang H, Keller G, Dwerryhouse S, Grimmer D, Chin SF, Yang HK, Jackson CE, Seruca R, Roviello F, Stupka E, Caldas C, Huntsman D.
|
| Hum Mol Genet 18(9):1545-55. Epub 2009 Jan 24.
2009
|
| 48 | CDH1, HDGC
|
| Quantification of Epigenetic and Genetic 2nd Hits in CDH1 During Hereditary Diffuse Gastric Cancer Syndrome Progression.
|
| Oliveira C, Sousa S, Pinheiro H, Karam R, Carriço R, Senz J, Kaurah P, Carvalho J, Pereira R, Gusmão L, Xiaogang W, Yokota J, Carneiro F, Huntsman D, Seruca R.
|
| Gastroenterology astroenterology. 2009 Mar 6. [Epub ahead of print]
2009
|
| 49 | CDH1, MGAT3, MGAT5
|
| The role of N-acetylglucosaminyltransferase III and V in the post-transcriptional modifications of E-cadherin.
|
| Pinho SS, Reis CA, Paredes J, Magalhães AM, Ferreira AC, Figueiredo J, Xiaogang W, Carneiro F, Gärtner F, Seruca R.
|
| Hum Mol Genet 18(14):2599-608. Epub 2009 Apr 29.
2009
|
| 50 | CDH1, CLDN1, VHL
|
| Regulation of renal epithelial tight junctions by the von Hippel-Lindau tumor suppressor gene involves occludin and claudin 1 and is independent of E-cadherin.
|
| Harten SK, Shukla D, Barod R, Hergovich A, Balda MS, Matter K, Esteban MA, Maxwell PH.
|
| Mol Biol Cell 20(3):1089-101. Epub 2008 Dec 10.PMID: 19073886 2009
|
| 51 | CDH1, RAC1, RHOA, RHOB
|
| Rac1 and Rho contribute to the migratory and invasive phenotype associated with somatic E-cadherin mutation.
|
| Deplazes J, Fuchs M, Rauser S, Genth H, Lengyel E, Busch R, Luber B.
|
| Hum Mol Genet 18(19):3632-44. Epub 2009 Jul 7.PMID: 19584084 2009
|
| 52 | CBX7, CDH1
|
| Chromobox protein homologue 7 protein, with decreased expression in human carcinomas, positively regulates E-cadherin expression by interacting with the histone deacetylase 2 protein.
|
| Federico A, Pallante P, Bianco M, Ferraro A, Esposito F, Monti M, Cozzolino M, Keller S, Fedele M, Leone V, Troncone G, Chiariotti L, Pucci P, Fusco A.
|
| Cancer Res 69(17):7079-87. Epub 2009 Aug 25.PMID: 19706751 2009
|
| 53 | CDC42, CDH1
|
| Cdc42 regulates E-cadherin ubiquitination and degradation through an epidermal growth factor receptor to Src-mediated pathway.
|
| Shen Y, Hirsch DS, Sasiela CA, Wu WJ.
|
| J Biol Chem 283(8):5127-37. Epub 2007 Dec 5. 2008
|
| 54 | CDH13, CDH1, RARB, BVES, KCNH5, MGMT
|
| DNA methylation in tumor and matched normal tissues from non-small cell lung cancer patients.
|
| Feng Q, Hawes SE, Stern JE, Wiens L, Lu H, Dong ZM, Jordan CD, Kiviat NB, Vesselle H.
|
| Cancer Epidemiol Biomarkers Prev 17(3):645-54. 2008
|
| 55 | APC, BRCA1, BRCA2, CDH1, CDKN2A, MLH1, MSH2, MSH6, PMS2, PRSS1, PTEN, RB1, SPINK1, STK11, TP53
|
| Inherited susceptibility to common cancers.
|
| Foulkes WD.
|
| N Engl J Med 359(20):2143-53. No abstract available.
2008
|
| 56 | CDH1
|
| Endoplasmic reticulum quality control: a new mechanism of E-cadherin regulation and its implication in cancer.
|
| Simões-Correia J, Figueiredo J, Oliveira C, van Hengel J, Seruca R, van Roy F, Suriano G.
|
| Hum Mol Genet 17(22):3566-76. Epub 2008 Sep 4.
2008
|
| 57 | CDH1
|
| APC/C Cdh1 targets aurora kinase to control reorganization of the mitotic spindle at anaphase.
|
| Floyd S, Pines J, Lindon C.
|
| Curr Biol 18(21):1649-58. Epub 2008 Oct 30.
2008
|
| 58 | CDH1
|
| The morphogenic function of E-cadherin-mediated adherens junctions in epithelial ovarian carcinoma formation and progression.
|
| Wu C, Cipollone J, Maines-Bandiera S, Tan C, Karsan A, Auersperg N, Roskelley CD.
|
| Differentiation 76(2):193-205. Epub 2007 Jul 2.PMID: 17608733 2008
|
| 59 | CDH1
|
| Identification of seven novel germline mutations in the human E-cadherin (CDH1) gene.
|
| More H, Humar B, Weber W, Ward R, Christian A, Lintott C, Graziano F, Ruzzo AM, Acosta E, Boman B, Harlan M, Ferreira P, Seruca R, Suriano G, Guilford P.
|
| Hum Mutat 28(2):203. 2007
|
| 60 | CDH1, ANK3
|
| Ankyrin-G Is a Molecular Partner of E-cadherin in Epithelial Cells and Early Embryos.
|
| Kizhatil K, Davis JQ, Davis L, Hoffman J, Hogan BL, Bennett V.
|
| J Biol Chem 282(36):26552-61. Epub 2007 Jul 9. 2007
|
| 61 | CDH1
|
| E-cadherin promotes retinal ganglion cell neurite outgrowth in a protein tyrosine phosphatase-mu-dependent manner.
|
| Oblander SA, Ensslen-Craig SE, Longo FM, Brady-Kalnay SM.
|
| Mol Cell Neurosci 34(3):481-92. Epub 2007 Feb 2.
2007
|
| 62 | CDH1
|
| E-cadherin and cell adhesion: a role in architecture and function in the pancreatic islet.
|
| Rogers GJ, Hodgkin MN, Squires PE.
|
| Cell Physiol Biochem 20(6):987-94.PMID: 17982281 2007
|
| 63 | CDH1, SNX1
|
| EGF induces macropinocytosis and SNX1-modulated recycling of E-cadherin.
|
| Bryant DM, Kerr MC, Hammond LA, Joseph SR, Mostov KE, Teasdale RD, Stow JL.
|
| J Cell Sci 120(Pt 10):1818-28.
2007
|
| 64 | CDH1
|
| E-cadherin promoter polymorphism (C-160A) and risk of recurrence in patients with superficial bladder cancer.
|
| Lin J, Dinney CP, Grossman HB, Jhamb M, Zhu Y, Spitz MR, Wu X.
|
| Clin Genet 70(3):240-5. 2006
|
| 65 | CDH1, HDGC
|
| Cleft lip/palate and CDH1/E-cadherin mutations in families with hereditary diffuse gastric cancer.
|
| Frebourg T, Oliveira C, Hochain P, Karam R, Manouvrier S, Graziadio C, Vekemans M, Hartmann A, Baert-Desurmont S, Alexandre C, Lejeune Dumoulin S, Marroni C, Martin C, Castedo S, Lovett M, Winston J, Machado JC, Attie T, Jabs EW, Cai J, Pellerin P, Triboulet JP, Scotte M, Le Pessot F, Hedouin A, Carneiro F, Blayau M, Seruca R.
|
| J Med Genet 43(2):138-42. Epub 2005 Apr 14. 2006
|
| 66 | CDH2, DIH1, ARRDC4, RGMA, DIH2, CDH1
|
| Array comparative genomic hybridization in patients with congenital diaphragmatic hernia: mapping of four CDH-critical regions and sequencing of candidate genes at 15q26.1-15q26.2.
|
| Slavotinek AM, Moshrefi A, Davis R, Leeth E, Schaeffer GB, Burchard GE, Shaw GM, James B, Ptacek L, Pennacchio LA.
|
| Eur J Hum Genet 14(9):999-1008. Epub 2006 May 31. 2006
|
| 67 | CDH1
|
| Association of E-cadherin gene 3'-UTR C/T polymorphism with primary open angle glaucoma.
|
| Lin HJ, Tsai FJ, Hung P, Chen WC, Chen HY, Fan SS, Tsai SW.
|
| Ophthalmic Res 38(1):44-8. Epub 2005 Nov 7. 2006
|
| 68 | CDH1
|
| E-cadherin polymorphisms and haplotypes influence risk for prostate cancer.
|
| Bonilla C, Mason T, Long L, Ahaghotu C, Chen W, Zhao A, Coulibaly A, Bennett F, Aiken W, Tullock T, Coard K, Freeman V, Kittles RA.
|
| Prostate 66(5):546-56. 2006
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| 69 | KLF6, CDH1
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| E-cadherin is a novel transcriptional target of the KLF6 tumor suppressor.
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| Oncogene 25(44):6026-31. Epub 2006 May 15. 2006
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| 70 | CDH1
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| Polymorphisms in the E-cadherin (CDH1) gene promoter and the risk of bladder cancer.
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| Eur J Cancer 42(18):3219-27. Epub 2006 Aug 28. 2006
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| 71 | CDH1, ADAM10
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| ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation.
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| Maretzky T, Reiss K, Ludwig A, Buchholz J, Scholz F, Proksch E, de Strooper B, Hartmann D, Saftig P.
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| Proc Natl Acad Sci U S A 102(26):9182-7. Epub 2005 Jun 15. 2005
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| 72 | SNAI1, CDH1, VDR, ZEB1
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| E-cadherin and vitamin D receptor regulation by SNAIL and ZEB1 in colon cancer: clinicopathological correlations.
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| Pena C, Garcia JM, Silva J, Garcia V, Rodriguez R, Alonso I, Millan I, Salas C, de Herreros AG, Munoz A, Bonilla F.
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| Hum Mol Genet 14(22):3361-70. Epub 2005 Oct 3. 2005
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| 73 | HDGC, CDH1, CTNNB1
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| Gastric cancer: new genetic developments.
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| Lynch HT, Grady W, Suriano G, Huntsman D.
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| J Surg Oncol 90(3):114-33; discussion 133. 2005
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| 74 | CDH1, HDGC
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| Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria.
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| Brooks-Wilson AR, Kaurah P, Suriano G, Leach S, Senz J, Grehan N, Butterfield YS, Jeyes J, Schinas J, Bacani J, Kelsey M, Ferreira P, MacGillivray B, MacLeod P, Micek M, Ford J, Foulkes W, Australie K, Greenberg C, LaPointe M, Gilpin C, Nikkel S, Gilchrist D, Hughes R, Jackson CE, Monaghan KG, Oliveira MJ, Seruca R, Gallinger S, Caldas C, Huntsman D.
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| J Med Genet 41(7):508-17. 2004
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| 75 | CDH1, WNT7A
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| WNT7a induces E-cadherin in lung cancer cells.
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| Ohira T, Gemmill RM, Ferguson K, Kusy S, Roche J, Brambilla E, Zeng C, Baron A, Bemis L, Erickson P, Wilder E, Rustgi A, Kitajewski J, Gabrielson E, Bremnes R, Franklin W, Drabkin HA.
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| Proc Natl Acad Sci U S A 100(18):10429-34. Epub 2003 Aug 22. 2003
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| 76 | ADGRG1, ALG5, APLP2, B3GNT3, BGN, C14orf1, CD151, CD99, CDH1, CDH32, CLPTM1, CNPY3, DAG1, DHX8, FXYD5, GDF15, HSP90B1, HSPA5, KRTCAP2, LAMA3, LMAN2, LYPD3, SPINT2, TEX261, TNFRSF12A
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| Identification of novel genes for secreted and membrane-anchored proteins in human keratinocytes.
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| Bonkobara M, Das A, Takao J, Cruz PD, Ariizumi K.
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| Br J Dermatol 148(4):654-64. 2003
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| 77 | CDH1
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| Differential expression, localization and activity of two alternatively spliced isoforms of human APC regulator CDH1.
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| Zhou Y, Ching YP, Ng RW, Jin DY.
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| Biochem J 374(Pt 2):349-58. 2003
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| 78 | CDH1, HDGC
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| Identification of CDH1 germline missense mutations associated with functional inactivation of the E-cadherin protein in young gastric cancer probands.
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| Suriano G, Oliveira C, Ferreira P, Machado JC, Bordin MC, De Wever O, Bruyneel EA, Moguilevsky N, Grehan N, Porter TR, Richards FM, Hruban RH, Roviello F, Huntsman D, Mareel M, Carneiro F, Caldas C, Seruca R.
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| Hum Mol Genet 12(5):575-82. 2003
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| 79 | AXIN1, AXIN2, CDH1, CTNNA1, JUP
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| Cadherin and catenin alterations in human cancer.
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| Hajra KM, Fearon ER.
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| Genes Chromosomes Cancer 34(3):255-68. Review. 2002
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| 80 | CDH1
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| Epigenetic control of the E-cadherin gene (CDH1) by CpG methylation in colectomy samples of patients with ulcerative colitis.
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| Azarschab P, Porschen R, Gregor M, Blin N, Holzmann K.
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| Genes Chromosomes Cancer 35(2):121-6. 2002
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| 81 | CAV1, CD44, CDH1, LPL, PMEPA1
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| Cytogenetics and molecular genetics of cancer of the prostate.
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| Brothman AR.
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| Am J Med Genet 115(3):150-6. 2002
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| 82 | CCND1, CDH1
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| Contribution of cyclin d1 (CCND1) and E-cadherin (CDH1) polymorphisms to familial and sporadic colorectal cancer.
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| Porter TR, Richards FM, Houlston RS, Evans DG, Jankowski JA, Macdonald F, Norbury G, Payne SJ, Fisher SA, Tomlinson I, Maher ER.
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| Oncogene 21(12):1928-33. 2002
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| 83 | CDH1
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| Single-nucleotide polymorphism in the E-cadherin gene promoter modifies the risk of prostate cancer.
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| Verhage BA, van Houwelingen K, Ruijter TE, Kiemeney LA, Schalken JA.
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| Int J Cancer 100(6):683-5. Erratum in: Int J Cancer 2002 Oct 20;101(6):600. 2002
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| 84 | CDH1
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| Altered expression of E-cadherin in hepatocellular carcinoma: correlations with genetic alterations, beta-catenin expression, and clinical features.
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| Wei Y, Van Nhieu JT, Prigent S, Srivatanakul P, Tiollais P, Buendia MA.
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| Hepatology 36(3):692-701. 2002
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| 85 | CDH1, HDGC
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| Screening E-cadherin in gastric cancer families reveals germline mutations only in hereditary diffuse gastric cancer kindred.
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| Oliveira C, Bordin MC, Grehan N, Huntsman D, Suriano G, Machado JC, Kiviluoto T, Aaltonen L, Jackson CE, Seruca R, Caldas C.
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| Hum Mutat 19(5):510-7. 2002
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| 86 | CDC20, CDH1, PTTG1
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| Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesis.
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| Zur A, Brandeis M.
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| EMBO J 20(4):792-801. 2001
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| 87 | CDH1, CTNNB1
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| The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin.
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| Huber AH, Weis WI.
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| Cell 105(3):391-402. 2001
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| 88 | CDH1
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| Mapping the chromosome 16 cadherin gene cluster to a minimal deleted region in ductal breast cancer.
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| Chalmers IJ, Aubele M, Hartmann E, Braungart E, Werner M, Hofler H, Atkinson MJ.
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| Cancer Genet Cytogenet 126(1):39-44. 2001
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| 89 | CDH1, HDGC
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| Early gastric cancer in young, asymptomatic carriers of germ-line E-cadherin mutations.
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| Huntsman DG, Carneiro F, Lewis FR, MacLeod PM, Hayashi A, Monaghan KG, Maung R, Seruca R, Jackson CE, Caldas C.
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| N Engl J Med 344(25):1904-9. 2001
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| 90 | CDH1, TSG16A
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| Aberrant DNA methylation precedes loss of heterozygosity on chromosome 16 in chronic hepatitis and liver cirrhosis.
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| Kanai Y, Ushijima S, Tsuda H, Sakamoto M, Hirohashi S.
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| Cancer Lett 148(1):73-80. 2000
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| 91 | CDH1, CDH16
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| Assignment of E-cadherin (CDH1) and KSP-cadherin (CDH16) to chromosome 16q22.1 by radiation hybrid mapping.
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| Baudry D, Jeanpierre C.
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| Cytogenet Cell Genet 88(3-4):253-4. No abstract available. 2000
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| 92 | CDH1
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| Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer.
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| Grady WM, Willis J, Guilford PJ, Dunbier AK, Toro TT, Lynch H, Wiesner G, Ferguson K, Eng C, Park JG, Kim SJ, Markowitz S.
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| Nat Genet 26(1):16-7. No abstract available. 2000
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| 93 | CDH1, CDH10, CDH11, CDH12, CDH12P, CDH13, CDH15, CDH16, CDH17, CDH18, CDH19, CDH2, CDH20, CDH23, CDH3, CDH4, CDH5, CDH6, CDH7, CDH8, CDH9, PCDH11Y, PCDHA@, PCDHA1, PCDHA10, PCDHA11, PCDHA12, PCDHA13, PCDHA14, PCDHA2, PCDHA3, PCDHA4, PCDHA5, PCDHA6, PCDHA7, PCDHA8, PCDHA9, PCDHACT, PCDHB1, PCDHB10, PCDHB11, PCDHB12, PCDHB13, PCDHB14, PCDHB15, PCDHB16, PCDHB2, PCDHB3, PCDHB4, PCDHB5, PCDHB6, PCDHB7, PCDHB8, PCDHB9, PCDHAC1, PCDHAC2, PCDHGA1, PCDHGA10, PCDHGA11, PCDHGA12, PCDHGA2, PCDHGA3, PCDHGA4, PCDHGA5, PCDHGA6, PCDHGA7, PCDHGA8, PCDHGA9, PCDHGB1, PCDHGB2, PCDHGB3, PCDHGB4, PCDHGB5, PCDHGB6, PCDHGB7, PCDHGC3, PCDHGC4, PCDHGC5, PCDHGCT
|
| Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.
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| Nollet F, Kools P, van Roy F.
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| J Mol Biol 299(3):551-72. Review. 2000
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| 94 | CDH1
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| Molecular alterations of E-cadherin gene: possible role in human bladder carcinogenesis.
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| Taddei I, Piazzini M, Bartoletti R, Dal Canto M, Sardi I.
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| Int J Mol Med 6(2):201-8. 2000
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| 95 | CDH1
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| Germline E-cadherin gene (CDH1) mutations predispose to familial gastric cancer and colorectal cancer.
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| Richards FM, et al.
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| Hum Mol Genet 8(4):607-10. 1999
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| 96 | CDH1
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| Mutated epithelial cadherin is associated with increased tumorigenicity and loss of adhesion and of responsiveness to the motogenic trefoil factor 2 in colon carcinoma cells.
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| Efstathiou JA, et al.
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| Proc Natl Acad Sci U S A 96(5):2316-21. 1999
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| 97 | CDH1, TSG16A
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| E-cadherin induces mesenchymal-to-epithelial transition in human ovarian surface epithelium.
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| Auersperg N, et al.
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| Proc Natl Acad Sci U S A 96(11):6249-54. 1999
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| 98 | CDH1, HDGC
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| E-cadherin germline mutations define an inherited cancer syndrome dominated by diffuse gastric cancer.
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| Guilford PJ, et al.
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| Hum Mutat 14(3):249-255 1999
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| 99 | CDH1
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| E-cadherin gene mutations are rare in adenocarcinomas of the oesophagus.
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| Br J Cancer 80(10):1652-7 1999
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| 100 | CDH1
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| Chromosome alterations and E-cadherin gene mutations in human lobular breast cancer.
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| Huiping C, Sigurgeirsdottir JR, Jonasson JG, Eiriksdottir G, Johannsdottir JT, Egilsson V, Ingvarsson S.
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| Br J Cancer 81(7):1103-10 1999
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| 101 | CDH1, TSG16A
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| E-cadherin germline mutations in familial gastric cancer.
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| Guilford P, et al.
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| Nature 392 : 402-405. 1998
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| 102 | CDH1, CDKN1A, KIT, MMP2, TFAP2A
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| Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells.
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| Jean D, et al.
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| J Biol Chem 273 : 16501-16508. 1998
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| 103 | CDH1
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| Mutations of the human E-cadherin (CDH1) gene.
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| Berx G, Becker KF, Hofler H, van Roy F.
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| Hum Mutat 12 : 226-237. 1998
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| 104 | CDH1
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| Insights from model systems. The tumor-suppressor function of E-cadherin.
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| Semb H, et al.
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| Am J Hum Genet 63 : 1588-1593. 1998
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| 105 | CDH1
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| Assignment of the E-cadherin gene (CDH1) to chromosome 16q22.1 by radiation hybrid mapping.
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| Huntsman DG, et al.
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| Cytogenet Cell Genet 83 : 82-83. 1998
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| 106 | CDH1, CDH13
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| H-cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer.
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| Lee SW.
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| Nat Med 2 : 776-782. 1996
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| 107 | CDH1
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| E-cadherin gene mutations in signet ring cell carcinoma of the stomach.
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| Jpn J Cancer Res 87 : 843-848. 1996
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| 108 | CDH1
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| Single nucleotide polymorphisms in the human E-cadherin gene.
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| Becker KF, et al.
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| Hum Genet 96 : 739-740. 1995
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| 109 | CDH1, TSG16A
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| E-cadherin is a tumour/invasion suppressor gene mutated in human lobularbreast cancers.
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| Berx G, et al.
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| EMBO J 14 : 6107-6115. 1995
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| 110 | CDH1
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| Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1).
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| Genomics 26 : 281-289. 1995
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| 111 | CDH1
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| Isolation and cDNA cloning of Ksp-cadherin, a novel kidney-specific member of the cadherin multigene family.
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| 112 | TSG16A, CDH1
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| 113 | CDH1
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| Molecular cloning of human E-cadherin suggests a novel subdivision of the cadherin superfamily.
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| Mol Biol Rep 17(2):123-8. 1993
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| 115 | CTRB1, CDH1
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| Regional assignment of the human loci for uvomorulin (UVO) and chymotrypsinogen (CTRB) with the help of two overlapping deletions on the long arm of chromosome 16.
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| 116 | CDH1
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| Regional assignment of the loci for uvomorulin (UVO) and chymotrypsinogen B (CTRB) on human chromosome 16q.
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| 117 | CDH1
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| Characterization and chromosomal localization of the gene encoding the human cell adhesion molecule uvomorulin.
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| 118 | CDH1
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