Citations for
1ANXA1, CDH1, SNAI1
Effect of Annexin A1 gene on the proliferation and invasion of esophageal squamous cell carcinoma cells and its regulatory mechanisms.
Han G, Lu K, Huang J, Ye J, Dai S, Ye Y, Zhang L.
Int J Mol Med 39(2):357-363. doi: 10.3892/ijmm.2016.2840. Epub 2016 Dec 28. 2017
2CDH1, GRHL3
Grhl3 induces human epithelial tumor cell migration and invasion via downregulation of E-cadherin.
Zhao P, Guo S, Tu Z, Di L, Zha X, Zhou H, Zhang X.
Acta Biochim Biophys Sin (Shanghai) 48(3):266-74. doi: 10.1093/abbs/gmw001. Epub 2016 Feb 1. 2016
3AHNAK, CDH1
AHNAK is downregulated in melanoma, predicts poor outcome, and may be required for the expression of functional cadherin-1.
Sheppard HM, Feisst V, Chen J, Print C, Dunbar PR.
Melanoma Res 26(2):108-16. doi: 10.1097/CMR.0000000000000228. 2016
4CDH1, MRCPH, MRDO, PLS3
Exome sequencing-based identification of mutations in non-syndromic genes among individuals with apparently syndromic features.
Nishi E, Masuda K, Arakawa M, Kawame H, Kosho T, Kitahara M, Kubota N, Hidaka E, Katoh Y, Shirahige K, Izumi K.
Am J Med Genet A 170(11):2889-2894. doi: 10.1002/ajmg.a.37826. 2016
5CDH1, CTNNB1, PROM1
CD133 expression correlates with membrane beta-catenin and E-cadherin loss from human hair follicle placodes during morphogenesis.
Gay DL, Yang CC, Plikus MV, Ito M, Rivera C, Treffeisen E, Doherty L, Spata M, Millar SE, Cotsarelis G.
J Invest Dermatol 135(1):45-55. doi: 10.1038/jid.2014.292. Epub 2014 Jul 10. 2015
6ADAM12, CDH1
ADAM12-directed ectodomain shedding of E-cadherin potentiates trophoblast fusion.
Aghababaei M, Hogg K, Perdu S, Robinson WP, Beristain AG.
Cell Death Differ 22(12):1970-84. doi: 10.1038/cdd.2015.44. 2015
7CDC20, CDH1, MAD2L2
Sequestration of CDH1 by MAD2L2 prevents premature APC/C activation prior to anaphase onset.
Listovsky T, Sale JE.
J Cell Biol 203(1):87-100. doi: 10.1083/jcb.201302060. Epub 2013 Oct 7. 2013
8CDH1, DSG2, SNAI1
The transcription factor Snail enhanced the degradation of E-cadherin and desmoglein 2 in oral squamous cell carcinoma cells.
Kume K, Haraguchi M, Hijioka H, Ishida T, Miyawaki A, Nakamura N, Ozawa M.
Biochem Biophys Res Commun 430(3):889-94. doi: 10.1016/j.bbrc.2012.12.060. Epub 2012 Dec 20. 2013
9CDH1, KLF4, ZEB2
Interplay between KLF4 and ZEB2/SIP1 in the regulation of E-cadherin expression.
Koopmansch B, Berx G, Foidart JM, Gilles C, Winkler R.
Biochem Biophys Res Commun 431(4):652-7. doi: 10.1016/j.bbrc.2013.01.070. Epub 2013 Jan 29. 2013
10CDH1, STAT3, ZEB1
Roles of STAT3 and ZEB1 proteins in E-cadherin down-regulation and human colorectal cancer epithelial-mesenchymal transition.
Xiong H, Hong J, Du W, Lin YW, Ren LL, Wang YC, Su WY, Wang JL, Cui Y, Wang ZH, Fang JY.
J Biol Chem 287(8):5819-32. doi: 10.1074/jbc.M111.295964. Epub 2011 Dec 28. 2012
11CDH1, GJA1, GJB2, TCF12
TCF12 protein functions as transcriptional repressor of E-cadherin, and its overexpression is correlated with metastasis of colorectal cancer.
Lee CC, Chen WS, Chen CC, Chen LL, Lin YS, Fan CS, Huang TS.
J Biol Chem 287(4):2798-809. doi: 10.1074/jbc.M111.258947. Epub 2011 Nov 30. 2012
12CDH1, RACK1
Rack1 promotes epithelial cell-cell adhesion by regulating E-cadherin endocytosis.
Swaminathan G, Cartwright CA.
Oncogene 31(3):376-89. doi: 10.1038/onc.2011.242. Epub 2011 Jun 20. 2012
13CDH1, CTNND1
Competitive regulation of E-cadherin juxtamembrane domain degradation by p120-catenin binding and Hakai-mediated ubiquitination.
Hartsock A, Nelson WJ.
PLoS One 7(5):e37476. doi: 10.1371/journal.pone.0037476. Epub 2012 May 31. 2012
14CDH1, SIK1
Salt-inducible kinase 1 regulates E-cadherin expression and intercellular junction stability.
Eneling K, Brion L, Pinto V, Pinho MJ, Sznajder JI, Mochizuki N, Emoto K, Soares-da-Silva P, Bertorello AM.
FASEB J 26(8):3230-9. doi: 10.1096/fj.12-205609. Epub 2012 Apr 20. 2012
15CDH1, GAB2, ZEB1
Gab2 regulates the migratory behaviors and E-cadherin expression via activation of the PI3K pathway in ovarian cancer cells.
Wang Y, Sheng Q, Spillman MA, Behbakht K, Gu H.
Oncogene 31(20):2512-20. doi: 10.1038/onc.2011.435. Epub 2011 Sep 26. 2012
16AKT2, CDH1, SNAI1
Akt2 interacts with Snail1 in the E-cadherin promoter.
Villagrasa P, Díaz VM, Viñas-Castells R, Peiró S, Del Valle-Pérez B, Dave N, Rodríguez-Asiain A, Casal JI, Lizcano JM, Duñach M, García de Herreros A.
Oncogene 31(36):4022-33. doi: 10.1038/onc.2011.562. 2012
17ATR, CDC6, CDH1
Hypoxic activation of ATR and the suppression of the initiation of DNA replication through cdc6 degradation.
Martin L, Rainey M, Santocanale C, Gardner LB.
Oncogene 31(36):4076-84. doi: 10.1038/onc.2011.585. 2012
18CDH1, RHOA, SMURF1
The E3 ligase Cdh1-anaphase promoting complex operates upstream of the E3 ligase Smurf1 in the control of axon growth.
Kannan M, Lee SJ, Schwedhelm-Domeyer N, Stegmüller J.
Development 139(19):3600-12. doi: 10.1242/dev.081786. 2012
19CDH1, ETV5, ZEB1
ETV5 cooperates with LPP as a sensor of extracellular signals and promotes EMT in endometrial carcinomas.
Colas E, Muinelo-Romay L, Alonso-Alconada L, Llaurado M, Monge M, Barbazan J, Gonzalez M, Schoumacher M, Pedrola N, Ertekin T, Devis L, Ruiz A, Castellvi J, Doll A, Gil-Moreno A, Vazquez-Levin M, Lapyckyj L, Lopez-Lopez R, Robine S, Friederich E, Castro M, Reventos J, Vignjevic D, Abal M.
Oncogene 31(45):4778-88. doi: 10.1038/onc.2011.632. Epub 2012 Jan 23. 2012
20ACTR2, ACTR3, CDH1, WASF2
A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens.
Verma S, Han SP, Michael M, Gomez GA, Yang Z, Teasdale RD, Ratheesh A, Kovacs EM, Ali RG, Yap AS.
Mol Biol Cell 23(23):4601-10. doi: 10.1091/mbc.E12-08-0574. Epub 2012 Oct 10. 2012
21CDH1, CDK2, USP37
Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry.
Huang X, Summers MK, Pham V, Lill JR, Liu J, Lee G, Kirkpatrick DS, Jackson PK, Fang G, Dixit VM.
Mol Cell 42(4):511-23. 2011
22ADAM10, CDH1, EPHB1, EPHB3
Cleavage of E-cadherin by ADAM10 mediates epithelial cell sorting downstream of EphB signalling.
Solanas G, Cortina C, Sevillano M, Batlle E.
Nat Cell Biol 13(9):1100-7. doi: 10.1038/ncb2298. 2011
23CDH1, MAGED1, TBX2
A pathway for the control of anoikis sensitivity by E-cadherin and epithelial-to-mesenchymal transition.
Kumar S, Park SH, Cieply B, Schupp J, Killiam E, Zhang F, Rimm DL, Frisch SM.
Mol Cell Biol 31(19):4036-51. Epub 2011 Jul 11. 2011
24CDH1
E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components.
Kim NG, Koh E, Chen X, Gumbiner BM.
Proc Natl Acad Sci U S A 108(29):11930-5. Epub 2011 Jul 5. 2011
25CDH1
E-cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming.
Redmer T, Diecke S, Grigoryan T, Quiroga-Negreira A, Birchmeier W, Besser D.
EMBO Rep 12(7):720-6. doi: 10.1038/embor.2011.88. 2011
26CDH1, MMP20
MMP20 cleaves E-cadherin and influences ameloblast development.
Bartlett JD, Yamakoshi Y, Simmer JP, Nanci A, Smith CE.
Cells Tissues Organs 194(2-4):222-6. Epub 2011 Apr 28. 2011
27CDH1
Down-regulation of epithelial cadherin is required to initiate metastatic outgrowth of breast cancer.
Wendt MK, Taylor MA, Schiemann BJ, Schiemann WP.
Mol Biol Cell 22(14):2423-35. Epub 2011 May 25. 2011
28CDH1, SMURF1
Cdh1 regulates osteoblast function through an APC/C-independent modulation of Smurf1.
Wan L, Zou W, Gao D, Inuzuka H, Fukushima H, Berg AH, Drapp R, Shaik S, Hu D, Lester C, Eguren M, Malumbres M, Glimcher LH, Wei W.
Mol Cell 44(5):721-33. doi: 10.1016/j.molcel.2011.09.024. 2011
29CDH1, FOXO3, IRS2
Insulin receptor substrate 2 and FoxO3a signalling are involved in E-cadherin expression and transforming growth factor-β1-induced repression in kidney epithelial cells.
Carew RM, Browne MB, Hickey FB, Brazil DP.
FEBS J 278(18):3370-80. doi: 10.1111/j.1742-4658.2011.08261.x. Epub 2011 Aug 16. 2011
30CDC6, CDH1
Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins.
Sideridou M, Zakopoulou R, Evangelou K, Liontos M, Kotsinas A, Rampakakis E, Gagos S, Kahata K, Grabusic K, Gkouskou K, Trougakos IP, Kolettas E, Georgakilas AG, Volarevic S, Eliopoulos AG, Zannis-Hadjopoulos M, Moustakas A, Gorgoulis VG.
J Cell Biol 195(7):1123-40. doi: 10.1083/jcb.201108121. 2011
31CDH1, CDH6
Distinct roles of cadherin-6 and E-cadherin in tubulogenesis and lumen formation.
Jia L, Liu F, Hansen SH, Ter Beest MB, Zegers MM.
Mol Biol Cell 22(12):2031-41. doi: 10.1091/mbc.E11-01-0038. 2011
32CDH1, CDH3, CTNND1, GNRH1
Cadherin switching and activation of p120 catenin signaling are mediators of gonadotropin-releasing hormone to promote tumor cell migration and invasion in ovarian cancer.
Cheung LW, Leung PC, Wong AS.
Oncogene 29(16):2427-40. Epub 2010 Feb 1. 2010
33CDH1, KLF4
Kruppel-like factor 4 inhibits epithelial-to-mesenchymal transition through regulation of E-cadherin gene expression.
Yori JL, Johnson E, Zhou G, Jain MK, Keri RA.
J Biol Chem 285(22):16854-63. Epub 2010 Mar 31. 2010
34CDH1, SMARCA4, ZEB1
ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1.
Sánchez-Tilló E, Lázaro A, Torrent R, Cuatrecasas M, Vaquero EC, Castells A, Engel P, Postigo A.
Oncogene 29(24):3490-500. Epub 2010 Apr 26. 2010
35CDH1, DNMT3A, EHMT1, MPHOSPH8, SETDB2
Methyl-H3K9-binding protein MPP8 mediates E-cadherin gene silencing and promotes tumour cell motility and invasion.
Kokura K, Sun L, Bedford MT, Fang J.
EMBO J 29(21):3673-87. Epub 2010 Sep 24.PMID: 20871592 2010
36CDH1, CDH3
Extracellular cleavage and shedding of P-cadherin: a mechanism underlying the invasive behaviour of breast cancer cells.
Ribeiro AS, Albergaria A, Sousa B, Correia AL, Bracke M, Seruca R, Schmitt FC, Paredes J.
Oncogene 29(3):392-402. Epub 2009 Nov 9. 2010
37CDH1, CDH3, GH1, ZEB2
Growth hormone (GH)-dependent expression of a natural antisense transcript induces zinc finger E-box-binding homeobox 2 (ZEB2) in the glomerular podocyte: a novel action of gh with implications for the pathogenesis of diabetic nephropathy.
Kumar PA, Kotlyarevska K, Dejkhmaron P, Reddy GR, Lu C, Bhojani MS, Menon RK.
J Biol Chem 285(41):31148-56. Epub 2010 Aug 3. 2010
38CDH1, PAK1
Pak1 control of E-cadherin endocytosis regulates salivary gland lumen size and shape.
Pirraglia C, Walters J, Myat MM.
Development 137(24):4177-89. Epub 2010 Nov 10. 2010
39CDH1, DDB1
Damaged DNA-binding protein 1 (DDB1) interacts with Cdh1 and modulates the function of APC/CCdh1.
Lv XB, Xie F, Hu K, Wu Y, Cao LL, Han X, Sang Y, Zeng YX, Kang T.
J Biol Chem 285(24):18234-40. Epub 2010 Apr 15. 2010
40CDH1, HDGC
Germline CDH1 deletions in hereditary diffuse gastric cancer families.
Oliveira C, Senz J, Kaurah P, Pinheiro H, Sanges R, Haegert A, Corso G, Schouten J, Fitzgerald R, Vogelsang H, Keller G, Dwerryhouse S, Grimmer D, Chin SF, Yang HK, Jackson CE, Seruca R, Roviello F, Stupka E, Caldas C, Huntsman D.
Hum Mol Genet 18(9):1545-55. Epub 2009 Jan 24. 2009
41CDH1, HDGC
Quantification of Epigenetic and Genetic 2nd Hits in CDH1 During Hereditary Diffuse Gastric Cancer Syndrome Progression.
Oliveira C, Sousa S, Pinheiro H, Karam R, Carriço R, Senz J, Kaurah P, Carvalho J, Pereira R, Gusmão L, Xiaogang W, Yokota J, Carneiro F, Huntsman D, Seruca R.
Gastroenterology astroenterology. 2009 Mar 6. [Epub ahead of print] 2009
42CDH1, MGAT3, MGAT5
The role of N-acetylglucosaminyltransferase III and V in the post-transcriptional modifications of E-cadherin.
Pinho SS, Reis CA, Paredes J, Magalhães AM, Ferreira AC, Figueiredo J, Xiaogang W, Carneiro F, Gärtner F, Seruca R.
Hum Mol Genet 18(14):2599-608. Epub 2009 Apr 29. 2009
43CDH1, CLDN1, VHL
Regulation of renal epithelial tight junctions by the von Hippel-Lindau tumor suppressor gene involves occludin and claudin 1 and is independent of E-cadherin.
Harten SK, Shukla D, Barod R, Hergovich A, Balda MS, Matter K, Esteban MA, Maxwell PH.
Mol Biol Cell 20(3):1089-101. Epub 2008 Dec 10.PMID: 19073886 2009
44CDH1, RAC1, RHOA, RHOB
Rac1 and Rho contribute to the migratory and invasive phenotype associated with somatic E-cadherin mutation.
Deplazes J, Fuchs M, Rauser S, Genth H, Lengyel E, Busch R, Luber B.
Hum Mol Genet 18(19):3632-44. Epub 2009 Jul 7.PMID: 19584084 2009
45CBX7, CDH1
Chromobox protein homologue 7 protein, with decreased expression in human carcinomas, positively regulates E-cadherin expression by interacting with the histone deacetylase 2 protein.
Federico A, Pallante P, Bianco M, Ferraro A, Esposito F, Monti M, Cozzolino M, Keller S, Fedele M, Leone V, Troncone G, Chiariotti L, Pucci P, Fusco A.
Cancer Res 69(17):7079-87. Epub 2009 Aug 25.PMID: 19706751 2009
46CDC42, CDH1
Cdc42 regulates E-cadherin ubiquitination and degradation through an epidermal growth factor receptor to Src-mediated pathway.
Shen Y, Hirsch DS, Sasiela CA, Wu WJ.
J Biol Chem 283(8):5127-37. Epub 2007 Dec 5. 2008
47CDH13, CDH1, RARB, BVES, KCNH5, MGMT
DNA methylation in tumor and matched normal tissues from non-small cell lung cancer patients.
Feng Q, Hawes SE, Stern JE, Wiens L, Lu H, Dong ZM, Jordan CD, Kiviat NB, Vesselle H.
Cancer Epidemiol Biomarkers Prev 17(3):645-54. 2008
48APC, BRCA1, BRCA2, CDH1, CDKN2A, MLH1, MSH2, MSH6, PMS2, PRSS1, PTEN, RB1, SPINK1, STK11, TP53
Inherited susceptibility to common cancers.
Foulkes WD.
N Engl J Med 359(20):2143-53. No abstract available. 2008
49CDH1
Endoplasmic reticulum quality control: a new mechanism of E-cadherin regulation and its implication in cancer.
Simões-Correia J, Figueiredo J, Oliveira C, van Hengel J, Seruca R, van Roy F, Suriano G.
Hum Mol Genet 17(22):3566-76. Epub 2008 Sep 4. 2008
50CDH1
APC/C Cdh1 targets aurora kinase to control reorganization of the mitotic spindle at anaphase.
Floyd S, Pines J, Lindon C.
Curr Biol 18(21):1649-58. Epub 2008 Oct 30. 2008
51CDH1
The morphogenic function of E-cadherin-mediated adherens junctions in epithelial ovarian carcinoma formation and progression.
Wu C, Cipollone J, Maines-Bandiera S, Tan C, Karsan A, Auersperg N, Roskelley CD.
Differentiation 76(2):193-205. Epub 2007 Jul 2.PMID: 17608733 2008
52CDH1
Identification of seven novel germline mutations in the human E-cadherin (CDH1) gene.
More H, Humar B, Weber W, Ward R, Christian A, Lintott C, Graziano F, Ruzzo AM, Acosta E, Boman B, Harlan M, Ferreira P, Seruca R, Suriano G, Guilford P.
Hum Mutat 28(2):203. 2007
53CDH1, ANK3
Ankyrin-G Is a Molecular Partner of E-cadherin in Epithelial Cells and Early Embryos.
Kizhatil K, Davis JQ, Davis L, Hoffman J, Hogan BL, Bennett V.
J Biol Chem 282(36):26552-61. Epub 2007 Jul 9. 2007
54CDH1
E-cadherin promotes retinal ganglion cell neurite outgrowth in a protein tyrosine phosphatase-mu-dependent manner.
Oblander SA, Ensslen-Craig SE, Longo FM, Brady-Kalnay SM.
Mol Cell Neurosci 34(3):481-92. Epub 2007 Feb 2. 2007
55CDH1
E-cadherin and cell adhesion: a role in architecture and function in the pancreatic islet.
Rogers GJ, Hodgkin MN, Squires PE.
Cell Physiol Biochem 20(6):987-94.PMID: 17982281 2007
56CDH1, SNX1
EGF induces macropinocytosis and SNX1-modulated recycling of E-cadherin.
Bryant DM, Kerr MC, Hammond LA, Joseph SR, Mostov KE, Teasdale RD, Stow JL.
J Cell Sci 120(Pt 10):1818-28. 2007
57CDH1
E-cadherin promoter polymorphism (C-160A) and risk of recurrence in patients with superficial bladder cancer.
Lin J, Dinney CP, Grossman HB, Jhamb M, Zhu Y, Spitz MR, Wu X.
Clin Genet 70(3):240-5. 2006
58CDH1, HDGC
Cleft lip/palate and CDH1/E-cadherin mutations in families with hereditary diffuse gastric cancer.
Frebourg T, Oliveira C, Hochain P, Karam R, Manouvrier S, Graziadio C, Vekemans M, Hartmann A, Baert-Desurmont S, Alexandre C, Lejeune Dumoulin S, Marroni C, Martin C, Castedo S, Lovett M, Winston J, Machado JC, Attie T, Jabs EW, Cai J, Pellerin P, Triboulet JP, Scotte M, Le Pessot F, Hedouin A, Carneiro F, Blayau M, Seruca R.
J Med Genet 43(2):138-42. Epub 2005 Apr 14. 2006
59CDH2, DIH1, ARRDC4, RGMA, DIH2, CDH1
Array comparative genomic hybridization in patients with congenital diaphragmatic hernia: mapping of four CDH-critical regions and sequencing of candidate genes at 15q26.1-15q26.2.
Slavotinek AM, Moshrefi A, Davis R, Leeth E, Schaeffer GB, Burchard GE, Shaw GM, James B, Ptacek L, Pennacchio LA.
Eur J Hum Genet 14(9):999-1008. Epub 2006 May 31. 2006
60CDH1
Association of E-cadherin gene 3'-UTR C/T polymorphism with primary open angle glaucoma.
Lin HJ, Tsai FJ, Hung P, Chen WC, Chen HY, Fan SS, Tsai SW.
Ophthalmic Res 38(1):44-8. Epub 2005 Nov 7. 2006
61CDH1
E-cadherin polymorphisms and haplotypes influence risk for prostate cancer.
Bonilla C, Mason T, Long L, Ahaghotu C, Chen W, Zhao A, Coulibaly A, Bennett F, Aiken W, Tullock T, Coard K, Freeman V, Kittles RA.
Prostate 66(5):546-56. 2006
62KLF6, CDH1
E-cadherin is a novel transcriptional target of the KLF6 tumor suppressor.
DiFeo A, Narla G, Camacho-Vanegas O, Nishio H, Rose SL, Buller RE, Friedman SL, Walsh MJ, Martignetti JA.
Oncogene 25(44):6026-31. Epub 2006 May 15. 2006
63CDH1
Polymorphisms in the E-cadherin (CDH1) gene promoter and the risk of bladder cancer.
Kiemeney LA, van Houwelingen KP, Bogaerts M, Witjes JA, Swinkels DW, den Heijer M, Franke B, Schalken JA, Verhaegh GW.
Eur J Cancer 42(18):3219-27. Epub 2006 Aug 28. 2006
64CDH1, ADAM10
ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation.
Maretzky T, Reiss K, Ludwig A, Buchholz J, Scholz F, Proksch E, de Strooper B, Hartmann D, Saftig P.
Proc Natl Acad Sci U S A 102(26):9182-7. Epub 2005 Jun 15. 2005
65SNAI1, CDH1, VDR, ZEB1
E-cadherin and vitamin D receptor regulation by SNAIL and ZEB1 in colon cancer: clinicopathological correlations.
Pena C, Garcia JM, Silva J, Garcia V, Rodriguez R, Alonso I, Millan I, Salas C, de Herreros AG, Munoz A, Bonilla F.
Hum Mol Genet 14(22):3361-70. Epub 2005 Oct 3. 2005
66HDGC, CDH1, CTNNB1
Gastric cancer: new genetic developments.
Lynch HT, Grady W, Suriano G, Huntsman D.
J Surg Oncol 90(3):114-33; discussion 133. 2005
67CDH1, HDGC
Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria.
Brooks-Wilson AR, Kaurah P, Suriano G, Leach S, Senz J, Grehan N, Butterfield YS, Jeyes J, Schinas J, Bacani J, Kelsey M, Ferreira P, MacGillivray B, MacLeod P, Micek M, Ford J, Foulkes W, Australie K, Greenberg C, LaPointe M, Gilpin C, Nikkel S, Gilchrist D, Hughes R, Jackson CE, Monaghan KG, Oliveira MJ, Seruca R, Gallinger S, Caldas C, Huntsman D.
J Med Genet 41(7):508-17. 2004
68CDH1, WNT7A
WNT7a induces E-cadherin in lung cancer cells.
Ohira T, Gemmill RM, Ferguson K, Kusy S, Roche J, Brambilla E, Zeng C, Baron A, Bemis L, Erickson P, Wilder E, Rustgi A, Kitajewski J, Gabrielson E, Bremnes R, Franklin W, Drabkin HA.
Proc Natl Acad Sci U S A 100(18):10429-34. Epub 2003 Aug 22. 2003
69ADGRG1, ALG5, APLP2, B3GNT3, BGN, C14orf1, CD151, CD99, CDH1, CDH32, CLPTM1, CNPY3, DAG1, DHX8, FXYD5, GDF15, HSP90B1, HSPA5, KRTCAP2, LAMA3, LMAN2, LYPD3, SPINT2, TEX261, TNFRSF12A
Identification of novel genes for secreted and membrane-anchored proteins in human keratinocytes.
Bonkobara M, Das A, Takao J, Cruz PD, Ariizumi K.
Br J Dermatol 148(4):654-64. 2003
70CDH1
Differential expression, localization and activity of two alternatively spliced isoforms of human APC regulator CDH1.
Zhou Y, Ching YP, Ng RW, Jin DY.
Biochem J 374(Pt 2):349-58. 2003
71CDH1, HDGC
Identification of CDH1 germline missense mutations associated with functional inactivation of the E-cadherin protein in young gastric cancer probands.
Suriano G, Oliveira C, Ferreira P, Machado JC, Bordin MC, De Wever O, Bruyneel EA, Moguilevsky N, Grehan N, Porter TR, Richards FM, Hruban RH, Roviello F, Huntsman D, Mareel M, Carneiro F, Caldas C, Seruca R.
Hum Mol Genet 12(5):575-82. 2003
72AXIN1, AXIN2, CDH1, CTNNA1, JUP
Cadherin and catenin alterations in human cancer.
Hajra KM, Fearon ER.
Genes Chromosomes Cancer 34(3):255-68. Review. 2002
73CDH1
Epigenetic control of the E-cadherin gene (CDH1) by CpG methylation in colectomy samples of patients with ulcerative colitis.
Azarschab P, Porschen R, Gregor M, Blin N, Holzmann K.
Genes Chromosomes Cancer 35(2):121-6. 2002
74CAV1, CD44, CDH1, LPL, PMEPA1
Cytogenetics and molecular genetics of cancer of the prostate.
Brothman AR.
Am J Med Genet 115(3):150-6. 2002
75CCND1, CDH1
Contribution of cyclin d1 (CCND1) and E-cadherin (CDH1) polymorphisms to familial and sporadic colorectal cancer.
Porter TR, Richards FM, Houlston RS, Evans DG, Jankowski JA, Macdonald F, Norbury G, Payne SJ, Fisher SA, Tomlinson I, Maher ER.
Oncogene 21(12):1928-33. 2002
76CDH1
Single-nucleotide polymorphism in the E-cadherin gene promoter modifies the risk of prostate cancer.
Verhage BA, van Houwelingen K, Ruijter TE, Kiemeney LA, Schalken JA.
Int J Cancer 100(6):683-5. Erratum in: Int J Cancer 2002 Oct 20;101(6):600. 2002
77CDH1
Altered expression of E-cadherin in hepatocellular carcinoma: correlations with genetic alterations, beta-catenin expression, and clinical features.
Wei Y, Van Nhieu JT, Prigent S, Srivatanakul P, Tiollais P, Buendia MA.
Hepatology 36(3):692-701. 2002
78CDH1, HDGC
Screening E-cadherin in gastric cancer families reveals germline mutations only in hereditary diffuse gastric cancer kindred.
Oliveira C, Bordin MC, Grehan N, Huntsman D, Suriano G, Machado JC, Kiviluoto T, Aaltonen L, Jackson CE, Seruca R, Caldas C.
Hum Mutat 19(5):510-7. 2002
79CDC20, CDH1, PTTG1
Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesis.
Zur A, Brandeis M.
EMBO J 20(4):792-801. 2001
80CDH1, CTNNB1
The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin.
Huber AH, Weis WI.
Cell 105(3):391-402. 2001
81CDH1
Mapping the chromosome 16 cadherin gene cluster to a minimal deleted region in ductal breast cancer.
Chalmers IJ, Aubele M, Hartmann E, Braungart E, Werner M, Hofler H, Atkinson MJ.
Cancer Genet Cytogenet 126(1):39-44. 2001
82CDH1, HDGC
Early gastric cancer in young, asymptomatic carriers of germ-line E-cadherin mutations.
Huntsman DG, Carneiro F, Lewis FR, MacLeod PM, Hayashi A, Monaghan KG, Maung R, Seruca R, Jackson CE, Caldas C.
N Engl J Med 344(25):1904-9. 2001
83CDH1, TSG16A
Aberrant DNA methylation precedes loss of heterozygosity on chromosome 16 in chronic hepatitis and liver cirrhosis.
Kanai Y, Ushijima S, Tsuda H, Sakamoto M, Hirohashi S.
Cancer Lett 148(1):73-80. 2000
84CDH1, CDH16
Assignment of E-cadherin (CDH1) and KSP-cadherin (CDH16) to chromosome 16q22.1 by radiation hybrid mapping.
Baudry D, Jeanpierre C.
Cytogenet Cell Genet 88(3-4):253-4. No abstract available. 2000
85CDH1
Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer.
Grady WM, Willis J, Guilford PJ, Dunbier AK, Toro TT, Lynch H, Wiesner G, Ferguson K, Eng C, Park JG, Kim SJ, Markowitz S.
Nat Genet 26(1):16-7. No abstract available. 2000
86CDH1, CDH10, CDH11, CDH12, CDH12P, CDH13, CDH15, CDH16, CDH17, CDH18, CDH19, CDH2, CDH20, CDH23, CDH3, CDH4, CDH5, CDH6, CDH7, CDH8, CDH9, PCDH11Y, PCDHA@, PCDHA1, PCDHA10, PCDHA11, PCDHA12, PCDHA13, PCDHA14, PCDHA2, PCDHA3, PCDHA4, PCDHA5, PCDHA6, PCDHA7, PCDHA8, PCDHA9, PCDHACT, PCDHB1, PCDHB10, PCDHB11, PCDHB12, PCDHB13, PCDHB14, PCDHB15, PCDHB16, PCDHB2, PCDHB3, PCDHB4, PCDHB5, PCDHB6, PCDHB7, PCDHB8, PCDHB9, PCDHAC1, PCDHAC2, PCDHGA1, PCDHGA10, PCDHGA11, PCDHGA12, PCDHGA2, PCDHGA3, PCDHGA4, PCDHGA5, PCDHGA6, PCDHGA7, PCDHGA8, PCDHGA9, PCDHGB1, PCDHGB2, PCDHGB3, PCDHGB4, PCDHGB5, PCDHGB6, PCDHGB7, PCDHGC3, PCDHGC4, PCDHGC5, PCDHGCT
Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.
Nollet F, Kools P, van Roy F.
J Mol Biol 299(3):551-72. Review. 2000
87CDH1
Molecular alterations of E-cadherin gene: possible role in human bladder carcinogenesis.
Taddei I, Piazzini M, Bartoletti R, Dal Canto M, Sardi I.
Int J Mol Med 6(2):201-8. 2000
88CDH1
Germline E-cadherin gene (CDH1) mutations predispose to familial gastric cancer and colorectal cancer.
Richards FM, et al.
Hum Mol Genet 8(4):607-10. 1999
89CDH1
Mutated epithelial cadherin is associated with increased tumorigenicity and loss of adhesion and of responsiveness to the motogenic trefoil factor 2 in colon carcinoma cells.
Efstathiou JA, et al.
Proc Natl Acad Sci U S A 96(5):2316-21. 1999
90CDH1, TSG16A
E-cadherin induces mesenchymal-to-epithelial transition in human ovarian surface epithelium.
Auersperg N, et al.
Proc Natl Acad Sci U S A 96(11):6249-54. 1999
91CDH1, HDGC
E-cadherin germline mutations define an inherited cancer syndrome dominated by diffuse gastric cancer.
Guilford PJ, et al.
Hum Mutat 14(3):249-255 1999
92CDH1
E-cadherin gene mutations are rare in adenocarcinomas of the oesophagus.
Wijnhoven BP, et al.
Br J Cancer 80(10):1652-7 1999
93CDH1
Chromosome alterations and E-cadherin gene mutations in human lobular breast cancer.
Huiping C, Sigurgeirsdottir JR, Jonasson JG, Eiriksdottir G, Johannsdottir JT, Egilsson V, Ingvarsson S.
Br J Cancer 81(7):1103-10 1999
94CDH1, TSG16A
E-cadherin germline mutations in familial gastric cancer.
Guilford P, et al.
Nature 392 : 402-405. 1998
95CDH1, CDKN1A, KIT, MMP2, TFAP2A
Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells.
Jean D, et al.
J Biol Chem 273 : 16501-16508. 1998
96CDH1
Mutations of the human E-cadherin (CDH1) gene.
Berx G, Becker KF, Hofler H, van Roy F.
Hum Mutat 12 : 226-237. 1998
97CDH1
Insights from model systems. The tumor-suppressor function of E-cadherin.
Semb H, et al.
Am J Hum Genet 63 : 1588-1593. 1998
98CDH1
Assignment of the E-cadherin gene (CDH1) to chromosome 16q22.1 by radiation hybrid mapping.
Huntsman DG, et al.
Cytogenet Cell Genet 83 : 82-83. 1998
99CDH1, CDH13
H-cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer.
Lee SW.
Nat Med 2 : 776-782. 1996
100CDH1
E-cadherin gene mutations in signet ring cell carcinoma of the stomach.
Muta H, et al.
Jpn J Cancer Res 87 : 843-848. 1996
101CDH1
Single nucleotide polymorphisms in the human E-cadherin gene.
Becker KF, et al.
Hum Genet 96 : 739-740. 1995
102CDH1, TSG16A
E-cadherin is a tumour/invasion suppressor gene mutated in human lobularbreast cancers.
Berx G, et al.
EMBO J 14 : 6107-6115. 1995
103CDH1
Cloning and characterization of the human invasion suppressor gene E-cadherin (CDH1).
Berx G, et al.
Genomics 26 : 281-289. 1995
104CDH1
Isolation and cDNA cloning of Ksp-cadherin, a novel kidney-specific member of the cadherin multigene family.
Thomson RB, et al.
J Biol Chem 270 : 17594-17601. 1995
105TSG16A, CDH1
Mutations of the E-cadherin gene in human gynecologic cancers.
Risinger JI, et al.
Nat Genet 7 : 98-102. 1994
106CDH1
Molecular cloning of human E-cadherin suggests a novel subdivision of the cadherin superfamily.
Rimm DL, et al.
Biochem Biophys Res Commun 200 : 1754-1761. 1994
107CDH1
Molecular cloning and characterization of the human E-cadherin cDNA.
Bussemakers MJ, van Bokhoven A, Mees SG, Kemler R, Schalken JA.
Mol Biol Rep 17(2):123-8. 1993
108CTRB1, CDH1
Regional assignment of the human loci for uvomorulin (UVO) and chymotrypsinogen (CTRB) with the help of two overlapping deletions on the long arm of chromosome 16.
Natt E, et al.
Cytogenet Cell Genet 50 : 145-148. 1989
109CDH1
Regional assignment of the loci for uvomorulin (UVO) and chymotrypsinogen B (CTRB) on human chromosome 16q.
Natt E, et al.
(HGM10) Cytogenet Cell Genet 51 : 1050-1051. 1989
110CDH1
Characterization and chromosomal localization of the gene encoding the human cell adhesion molecule uvomorulin.
Mansouri A, et al.
Differentiation 38 : 67-71. 1988
111CDH1
Molecular cloning and chromosomal localization of the human cell adhesion molecule uvomorulin (UVO).
Mansouri A, et al.
(HGM9) Cytogenet Cell Genet 46 : 655. 1987