| 1 | CDC7, DBF4
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| Molecular mechanism of activation of human Cdc7 kinase: bipartite interaction with Dbf4/activator of S phase kinase (ASK) activation subunit stimulates ATP binding and substrate recognition.
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| Kitamura R, Fukatsu R, Kakusho N, Cho YS, Taniyama C, Yamazaki S, Toh GT, Yanagi K, Arai N, Chang HJ, Masai H.
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| J Biol Chem 286(26):23031-43. Epub 2011 May 2.
2011
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| 2 | CDC7, POLH, RAD18
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| Phosphorylated Rad18 directs DNA polymerase η to sites of stalled replication.
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| Day TA, Palle K, Barkley LR, Kakusho N, Zou Y, Tateishi S, Verreault A, Masai H, Vaziri C.
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| J Cell Biol 191(5):953-66. Epub 2010 Nov 22.
2010
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| 3 | CDC7, DBF4
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| Dbf4 regulates the Cdc5 Polo-like kinase through a distinct non-canonical binding interaction.
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| Chen YC, Weinreich M.
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| J Biol Chem 285(53):41244-54. Epub 2010 Oct 29.
2010
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| 4 | CDC7
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| Targeting cell division cycle 7 kinase: a new approach for cancer therapy.
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| Montagnoli A, Moll J, Colotta F.
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| Clin Cancer Res 16(18):4503-8. Epub 2010 Jul 20. Review.
2010
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| 5 | CDC45, CDC7, CDT1
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| Human CDT1 associates with CDC7 and recruits CDC45 to chromatin during S phase.
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| Ballabeni A, Zamponi R, Caprara G, Melixetian M, Bossi S, Masiero L, Helin K.
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| J Biol Chem 284(5):3028-36. Epub 2008 Dec 3.
2009
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| 6 | CDC7, DBF4
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| Cdc7p-Dbf4p regulates mitotic exit by inhibiting Polo kinase.
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| Miller CT, Gabrielse C, Chen YC, Weinreich M.
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| PLoS Genet 5(5):e1000498. Epub 2009 May 29.
2009
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| 7 | CDC7
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| Cdc7 kinase is a predictor of survival and a novel therapeutic target in epithelial ovarian carcinoma.
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| Kulkarni AA, Kingsbury SR, Tudzarova S, Hong HK, Loddo M, Rashid M, Rodriguez-Acebes S, Prevost AT, Ledermann JA, Stoeber K, Williams GH.
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| Clin Cancer Res 15(7):2417-25. Epub 2009 Mar 24.
2009
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| 8 | CDC7, CLSPN
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| Cdc7 kinase mediates Claspin phosphorylation in DNA replication checkpoint.
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| Kim JM, Kakusho N, Yamada M, Kanoh Y, Takemoto N, Masai H.
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| Oncogene 27(24):3475-82. Epub 2007 Dec 17.PMID: 18084324 2008
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| 9 | CDC7, DBF4, MCM2
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| Inhibition of Cdc7/Dbf4 kinase activity affects specific phosphorylation sites on MCM2 in cancer cells.
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| Charych DH, Coyne M, Yabannavar A, Narberes J, Chow S, Wallroth M, Shafer C, Walter AO.
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| J Cell Biochem 104(3):1075-86.
2008
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| 10 | CDC7
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| Identification and characterization of human cdc7 nuclear retention and export sequences in the context of chromatin binding.
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| Kim BJ, Kim SY, Lee H.
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| J Biol Chem 282(41):30029-38. Epub 2007 Aug 20. 2007
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| 11 | CDC7
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| Cdc7 is an active kinase in human cancer cells undergoing replication stress.
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| Tenca P, Brotherton D, Montagnoli A, Rainoldi S, Albanese C, Santocanale C.
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| J Biol Chem 282(1):208-15. Epub 2006 Oct 24. 2007
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| 12 | MCM2, MCM4, MCM6, CDC7
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| Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin.
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| Masai H, Taniyama C, Ogino K, Matsui E, Kakusho N, Matsumoto S, Kim JM, Ishii A, Tanaka T, Kobayashi T, Tamai K, Ohtani K, Arai K.
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| J Biol Chem 281(51):39249-61. Epub 2006 Oct 17. 2006
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| 13 | CDC7
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| Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells.
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| Tsuji T, Ficarro SB, Jiang W.
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| Mol Biol Cell 17(10):4459-72. Epub 2006 Aug 9. 2006
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| 14 | CDC7
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| CDC7 kinase phosphorylates serine residues adjacent to acidic amino acids in the minichromosome maintenance 2 protein.
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| Cho WH, Lee YJ, Kong SI, Hurwitz J, Lee JK.
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| Proc Natl Acad Sci U S A 103(31):11521-6. Epub 2006 Jul 24. 2006
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| 15 | CHAF1A, CDC7, DFB4
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| The replication kinase Cdc7-Dbf4 promotes the interaction of the p150 subunit of chromatin assembly factor 1 with proliferating cell nuclear antigen.
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| Grard A, Koundrioukoff S, Ramillon V, Sergre JC, Mailand N, Quivy JP, Almouzni G.
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| EMBO Rep 7(8):817-23. Epub 2006 Jul 7. 2006
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| 16 | CDC7
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| Hypomorphic mutation in an essential cell-cycle kinase causes growth retardation and impaired spermatogenesis.
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| Kim JM, Takemoto N, Arai K, Masai H.
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| EMBO J 22(19):5260-72. 2003
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| 17 | CDC7
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| A human homolog of the yeast CDC7 gene is overexpressed in some tumors and transformed cell lines.
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| Hess GF, Drong RF, Weiland KL, Slightom JL, Sclafani RA, Hollingsworth RE.
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| Gene 211(1):133-40. 1998
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| 18 | CDC7
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| Human and xenopus cDNAs encoding budding yeast Cdc7-related kinases : in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7.
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| Sato N, et al.
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| EMBO J 16 : 4340-4351. 1997
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| 19 | CDC7, MCM3
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| Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7.
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| Sato N, Arai K, Masai H.
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| EMBO J 16(14):4340-51. 1997
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| 20 | CDC7
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| Identification and characterization of a human protein kinase related to budding yeast Cdc7p.
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| Jiang W, Hunter T.
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| Proc Natl Acad Sci U S A 94(26):14320-5. 1997
|