| 1 | CDC42, PAK2
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| PAK2 activated by Cdc42 and caspase 3 mediates different cellular responses to oxidative stress-induced apoptosis
|
| Huang J, Huang A, Poplawski A, DiPino F Jr, Traugh JA, Ling J.
|
| Biochim Biophys Acta Mol Cell Res. Apr;1867(4):118645. doi: 10.1016/j.bbamcr.2020.118645. Epub 2020 Jan 8. 2020
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| 2 | CDC42, ODF2
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| CCDC42 Localizes to Manchette, HTCA and Tail and Interacts With ODF1 and ODF2 in the Formation of the Male Germ Cell Cytoskeleton.
|
| Tapia Contreras C, Hoyer-Fender S.
|
| Front Cell Dev Biol. Aug 14;7:151. doi: 10.3389/fcell.2019.00151. eCollection 2019. 2019
|
| 3 | CDC42, MTCMR
|
| Functional Dysregulation of CDC42 Causes Diverse Developmental Phenotypes.
|
| Martinelli S, Krumbach OHF, Pantaleoni F, Coppola S, Amin E, Pannone L, Nouri K, Farina L, Dvorsky R, Lepri F, Buchholzer M, Konopatzki R, Walsh L, Payne K, Pierpont ME, Vergano SS, Langley KG, Larsen D, Farwell KD, Tang S, Mroske C, Gallotta I, Di Schiavi E, Della Monica M, Lugli L, Rossi C, Seri M, Cocchi G, Henderson L, Baskin B, Alders M, Mendoza-Londono R, Dupuis L, Nickerson DA, Chong JX; University of Washington Center for Mendelian Genomics, Meeks N, Brown K, Causey T, Cho MT, Demuth S, Digilio MC, Gelb BD, Bamshad MJ, Zenker M, Ahmadian MR, Hennekam RC, Tartaglia M, Mirzaa GM.
|
| Am J Hum Genet m J Hum Genet. 2018 Jan 17. pii: S0002-9297(17)30504-9. doi: 10.1016/j.ajhg.2017.12.015. [Epub ahead of print]
2018
|
| 4 | CDC42, WNT4
|
| An Osteoporosis Risk SNP at 1p36.12 Acts as an Allele-Specific Enhancer to Modulate LINC00339 Expression via Long-Range Loop Formation.
|
| Chen XF, Zhu DL, Yang M, Hu WX, Duan YY, Lu BJ, Rong Y, Dong SS, Hao RH, Chen JB, Chen YX, Yao S, Thynn HN, Guo Y, Yang TL.
|
| Am J Hum Genet 102(5):776-793. doi: 10.1016/j.ajhg.2018.03.001. Epub 2018 Apr 26.
2018
|
| 5 | CDC42, RASIP1
|
| Rasip1 controls lymphatic vessel lumen maintenance by regulating endothelial cell junctions.
|
| Liu X, Gu X, Ma W, Oxendine M, Gil HJ, Davis GE, Cleaver O, Oliver G.
|
| Development 145(17). pii: dev165092. doi: 10.1242/dev.165092.
2018
|
| 6 | CDC42, ITSN1, ITSN2
|
| Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment.
|
| Ashraf S, Kudo H, Rao J, Kikuchi A, Widmeier E, Lawson JA, Tan W, Hermle T, Warejko JK, Shril S, Airik M, Jobst-Schwan T, Lovric S, Braun DA, Gee HY, Schapiro D, Majmundar AJ, Sadowski CE, Pabst WL, Daga A, van der Ven AT, Schmidt JM, Low BC, Gupta AB, Tripathi BK, Wong J, Campbell K, Metcalfe K, Schanze D, Niihori T, Kaito H, Nozu K, Tsukaguchi H, Tanaka R, Hamahira K, Kobayashi Y, Takizawa T, Funayama R, Nakayama K, Aoki Y, Kumagai N, Iijima K, Fehrenbach H, Kari JA, El Desoky S, Jalalah S, Bogdanovic R, Stajić N, Zappel H, Rakhmetova A, Wassmer SR, Jungraithmayr T, Strehlau J, Kumar AS, Bagga A, Soliman NA, Mane SM, Kaufman L, Lowy DR, Jairajpuri MA, Lifton RP, Pei Y, Zenker M, Kure S, Hildebrandt F.
|
| Nat Commun 9(1):1960. doi: 10.1038/s41467-018-04193-w.
2018
|
| 7 | CDC42, DOCK8, LURAP1
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| DOCK8 Protein Regulates Macrophage Migration through Cdc42 Protein Activation and LRAP35a Protein Interaction.
|
| Shiraishi A, Uruno T, Sanematsu F, Ushijima M, Sakata D, Hara T, Fukui Y.
|
| J Biol Chem 292(6):2191-2202. doi: 10.1074/jbc.M116.736306. Epub 2016 Dec 27.
2017
|
| 8 | CDC42, DOCK8, LRCH1
|
| LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis
|
| Xu X, Han L, Zhao G, Xue S, Gao Y, Xiao J, Zhang S, Chen P, Wu ZY, Ding J, Hu R, Wei B, Wang H.
|
| J Exp Med. Jan;214(1):209-226. doi: 10.1084/jem.20160068. 2017
|
| 9 | CDC42, GOPC, GRID2
|
| Potential of GRID2 receptor gene for preventing TNF-induced neurodegeneration in autism.
|
| Kalkan Z, Durasi İM, Sezerman U, Atasever-Arslan B.
|
| Neurosci Lett 620:62-9. doi: 10.1016/j.neulet.2016.03.043. Epub 2016 Mar 25.
2016
|
| 10 | CDC42, MTCMR
|
| Further evidence of a mutation in CDC42 as a cause of a recognizable syndromic form of thrombocytopenia.
|
| Takenouchi T, Okamoto N, Ida S, Uehara T, Kosaki K.
|
| Am J Med Genet A 170A(4):852-5. doi: 10.1002/ajmg.a.37526. Epub 2015 Dec 28.
2016
|
| 11 | CDC42, WASL, YAP1
|
| Cdc42 deficiency induces podocyte apoptosis by inhibiting the Nwasp/stress fibers/YAP pathway.
|
| Huang Z, Zhang L, Chen Y, Zhang H, Zhang Q, Li R, Ma J, Li Z, Yu C, Lai Y, Lin T, Zhao X, Zhang B, Ye Z, Liu S, Wang W, Liang X, Liao R, Shi W.
|
| Cell Death Dis 7:e2142. doi: 10.1038/cddis.2016.51.
2016
|
| 12 | CDC42, WASL
|
| The cell division control protein 42-Src family kinase-neural Wiskott-Aldrich syndrome protein pathway regulates human proplatelet formation.
|
| Palazzo A, Bluteau O, Messaoudi K, Marangoni F, Chang Y, Souquere S, Pierron G, Lapierre V, Zheng Y, Vainchenker W, Raslova H, Debili N.
|
| J Thromb Haemost 14(12):2524-2535. doi: 10.1111/jth.13519. Epub 2016 Nov 15.
2016
|
| 13 | CDC42, ERRFI1
|
| Inhibition of Cdc42 is essential for Mig-6 suppression of cell migration induced by EGF.
|
| Jiang X, Niu M, Chen D, Chen J, Cao Y, Li X, Ying H, Bergholz J, Zhang Y, Xiao ZX.
|
| Oncotarget 7(31):49180-49193. doi: 10.18632/oncotarget.10205.
2016
|
| 14 | CDC42, PICK1, RAC1
|
| PICK1 links AMPA receptor stimulation to Cdc42.
|
| Rocca DL, Hanley JG.
|
| Neurosci Lett 585:155-9. doi: 10.1016/j.neulet.2014.11.046. Epub 2014 Dec 2.
2015
|
| 15 | CDC42, MARCKS, RAC1
|
| Myristoylated Alanine-Rich Protein Kinase Substrate (MARCKS) Regulates Small GTPase Rac1 and Cdc42 Activity and Is a Critical Mediator of Vascular Smooth Muscle Cell Migration in Intimal Hyperplasia Formation.
|
| Yu D, Makkar G, Strickland DK, Blanpied TA, Stumpo DJ, Blackshear PJ, Sarkar R, Monahan TS.
|
| J Am Heart Assoc 4(10):e002255. doi: 10.1161/JAHA.115.002255.
2015
|
| 16 | CDC42, EPHB2, PAK3
|
| Regulation of AMPA receptor subunit GluA1 surface expression by PAK3 phosphorylation.
|
| Hussain NK, Thomas GM, Luo J, Huganir RL.
|
| Proc Natl Acad Sci U S A 112(43):E5883-90. doi: 10.1073/pnas.1518382112. Epub 2015 Oct 12.
2015
|
| 17 | CDC42, MTCMR
|
| Macrothrombocytopenia and developmental delay with a de novo CDC42 mutation: Yet another locus for thrombocytopenia and developmental delay.
|
| Takenouchi T, Kosaki R, Niizuma T, Hata K, Kosaki K.
|
| Am J Med Genet A 167A(11):2822-5. doi: 10.1002/ajmg.a.37275. Epub 2015 Aug 6.
2015
|
| 18 | ATP8B1, CDC42
|
| ATP8B1-mediated spatial organization of Cdc42 signaling maintains singularity during enterocyte polarization.
|
| Bruurs LJ, Donker L, Zwakenberg S, Zwartkruis FJ, Begthel H, Knisely AS, Posthuma G, van de Graaf SF, Paulusma CC, Bos JL.
|
| J Cell Biol 210(7):1055-63. doi: 10.1083/jcb.201505118.
2015
|
| 19 | CDC42, PTBP1
|
| Regulation and functional significance of CDC42 alternative splicing in ovarian cancer.
|
| He X, Yuan C, Yang J.
|
| Oncotarget 6(30):29651-63. doi: 10.18632/oncotarget.4865.
2015
|
| 20 | ARF1, ARHGAP21, CDC42
|
| CLN3 deficient cells display defects in the ARF1-Cdc42 pathway and actin-dependent events.
|
| Schultz ML, Tecedor L, Stein CS, Stamnes MA, Davidson BL.
|
| PLoS One 9(5):e96647. doi: 10.1371/journal.pone.0096647. eCollection 2014.
2014
|
| 21 | CDC42
|
| DNA binding properties of human Cdc45 suggest a function as molecular wedge for DNA unwinding.
|
| Szambowska A, Tessmer I, Kursula P, Usskilat C, Prus P, Pospiech H, Grosse F.
|
| Nucleic Acids Res 42(4):2308-19. doi: 10.1093/nar/gkt1217. Epub 2013 Nov 28.
2014
|
| 22 | CDC42, SH3PXD2A
|
| Cdc42 and Tks5: a minimal and universal molecular signature for functional invadosomes.
|
| Di Martino J, Paysan L, Gest C, Lagrée V, Juin A, Saltel F, Moreau V.
|
| Cell Adh Migr 8(3):280-92.
2014
|
| 23 | CDC42, RAC1, RACGAP1
|
| Deletion of MgcRacGAP in the male germ cells impairs spermatogenesis and causes male sterility in the mouse.
|
| Lorès P, Vernet N, Kurosaki T, Van de Putte T, Huylebroeck D, Hikida M, Gacon G, Touré A.
|
| Dev Biol 386(2):419-27. doi: 10.1016/j.ydbio.2013.12.006.
2014
|
| 24 | CDC42, RHOA, STARD13
|
| StarD13 is a tumor suppressor in breast cancer that regulates cell motility and invasion.
|
| Hanna S, Khalil B, Nasrallah A, Saykali BA, Sobh R, Nasser S, El-Sibai M.
|
| Int J Oncol 44(5):1499-511. doi: 10.3892/ijo.2014.2330. Epub 2014 Mar 7.
2014
|
| 25 | CDC42, ITSN1, NCK1, WASL
|
| Cdc42 and the Rho GEF intersectin-1 collaborate with Nck to promote N-WASP-dependent actin polymerisation.
|
| Humphries AC, Donnelly SK, Way M.
|
| J Cell Sci 127(Pt 3):673-85. doi: 10.1242/jcs.141366. Epub 2013 Nov 27.
2014
|
| 26 | CDC42, EXOC5
|
| Cdc42 Deficiency Causes Ciliary Abnormalities and Cystic Kidneys.
|
| Choi SY, Chacon-Heszele MF, Huang L, McKenna S, Wilson FP, Zuo X, Lipschutz JH.
|
| J Am Soc Nephrol Am Soc Nephrol. 2013 Jun 13. [Epub ahead of print]
2013
|
| 27 | BAIAP2, CDC42, TGFBR3, WAS
|
| The Type III TGF-β receptor regulates filopodia formation via a Cdc42-mediated IRSP53: NWASP interaction in epithelial cells.
|
| Oh SY, Knelson EH, Blobe GC, Mythreye K.
|
| Biochem J iochem J. 2013 Jun 10. [Epub ahead of print]
2013
|
| 28 | CDC42, DOCK7
|
| Prenylation and Membrane Localization of Cdc42 Are Essential for Activation by DOCK7.
|
| Zhou Y, Johnson JL, Cerione RA, Erickson JW.
|
| Biochemistry iochemistry. 2013 Jun 14. [Epub ahead of print]
2013
|
| 29 | CDC42
|
| Cdc42 promotes host defenses against fatal infection.
|
| Lee K, Boyd KL, Parekh DV, Kehl-Fie TE, Baldwin HS, Brakebusch C, Skaar EP, Boothby M, Zent R.
|
| Infect Immun nfect Immun. 2013 May 20. [Epub ahead of print]
2013
|
| 30 | CDC42, RAC1
|
| Divergent functions of the Rho GTPases Rac1 and Cdc42 in podocyte injury.
|
| Blattner SM, Hodgin JB, Nishio M, Wylie SA, Saha J, Soofi AA, Vining C, Randolph A, Herbach N, Wanke R, Atkins KB, Gyung Kang H, Henger A, Brakebusch C, Holzman LB, Kretzler M.
|
| Kidney Int idney Int. 2013 May 15. doi: 10.1038/ki.2013.175. [Epub ahead of print]
2013
|
| 31 | CDC42
|
| Cdc42 interacts with the exocyst complex to promote phagocytosis.
|
| Mohammadi S, Isberg RR.
|
| J Cell Biol 200(1):81-93. doi: 10.1083/jcb.201204090.
2013
|
| 32 | CDC42, RAC1
|
| Stage-specific functions of the small Rho GTPases Cdc42 and Rac1 for adult hippocampal neurogenesis.
|
| Vadodaria KC, Brakebusch C, Suter U, Jessberger S.
|
| J Neurosci 33(3):1179-89. doi: 10.1523/JNEUROSCI.2103-12.2013.
2013
|
| 33 | CDC42
|
| CDC42 is required for structural patterning of the lung during development.
|
| Wan H, Liu C, Wert SE, Xu W, Liao Y, Zheng Y, Whitsett JA.
|
| Dev Biol 374(1):46-57. doi: 10.1016/j.ydbio.2012.11.030. Epub 2012 Dec 5.
2013
|
| 34 | ARHGAP21, CDC42, TUBA1B
|
| ARHGAP21 protein, a new partner of α-tubulin involved in cell-cell adhesion formation and essential for epithelial-mesenchymal transition.
|
| Barcellos KS, Bigarella CL, Wagner MV, Vieira KP, Lazarini M, Langford PR, Machado-Neto JA, Call SG, Staley DM, Chung JY, Hansen MD, Saad ST.
|
| J Biol Chem 288(4):2179-89. doi: 10.1074/jbc.M112.432716. Epub 2012 Dec 12.
2013
|
| 35 | CDC42, ITSN1
|
| Small molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility.
|
| Friesland A, Zhao Y, Chen YH, Wang L, Zhou H, Lu Q.
|
| Proc Natl Acad Sci U S A 110(4):1261-6. doi: 10.1073/pnas.1116051110. Epub 2013 Jan 2.
2013
|
| 36 | CDC42, FGF8
|
| Regulation of neurogenesis by Fgf8a requires Cdc42 signaling and a novel Cdc42 effector protein.
|
| Hulstrand AM, Houston DW.
|
| Dev Biol 382(2):385-99. doi: 10.1016/j.ydbio.2013.08.020. Epub 2013 Aug 29.
2013
|
| 37 | CDC42, GNAQ
|
| Histaminylation of glutamine residues is a novel posttranslational modification implicated in G-protein signaling.
|
| Vowinckel J, Stahlberg S, Paulmann N, Bluemlein K, Grohmann M, Ralser M, Walther DJ.
|
| FEBS Lett 586(21):3819-24. doi: 10.1016/j.febslet.2012.09.027. Epub 2012 Sep 26.
2012
|
| 38 | CDC42
|
| Cdc42 promotes transendothelial migration of cancer cells through β1 integrin.
|
| Reymond N, Im JH, Garg R, Vega FM, Borda d'Agua B, Riou P, Cox S, Valderrama F, Muschel RJ, Ridley AJ.
|
| J Cell Biol 199(4):653-68. doi: 10.1083/jcb.201205169.
2012
|
| 39 | CDC42, EDN1
|
| Endothelin-1 stimulates human trophoblast cell migration through Cdc42 activation.
|
| Liu S, Li Q, Na Q, Liu C.
|
| Placenta 33(9):712-6. doi: 10.1016/j.placenta.2012.06.010. Epub 2012 Jul 6.
2012
|
| 40 | CDC42
|
| Essential role of Cdc42 in Ras-induced transformation revealed by gene targeting.
|
| Stengel KR, Zheng Y.
|
| PLoS One 7(6):e37317. doi: 10.1371/journal.pone.0037317. Epub 2012 Jun 18.
2012
|
| 41 | CDC42
|
| Podocyte-specific loss of Cdc42 leads to congenital nephropathy.
|
| Scott RP, Hawley SP, Ruston J, Du J, Brakebusch C, Jones N, Pawson T.
|
| J Am Soc Nephrol 23(7):1149-54. doi: 10.1681/ASN.2011121206. Epub 2012 Apr 19.
2012
|
| 42 | CDC42, PTK2
|
| Focal adhesion kinase modulates Cdc42 activity downstream of positive and negative axon guidance cues.
|
| Myers JP, Robles E, Ducharme-Smith A, Gomez TM.
|
| J Cell Sci 125(Pt 12):2918-29. doi: 10.1242/jcs.100107. Epub 2012 Mar 5.
2012
|
| 43 | CDC42
|
| Oscillatory dynamics of Cdc42 GTPase in the control of polarized growth.
|
| Das M, Drake T, Wiley DJ, Buchwald P, Vavylonis D, Verde F.
|
| Science 337(6091):239-43. doi: 10.1126/science.1218377. Epub 2012 May 17.
2012
|
| 44 | CDC42, PARD3, PARD6A
|
| Nuclear movement during myotube formation is microtubule and dynein dependent and is regulated by Cdc42, Par6 and Par3.
|
| Cadot B, Gache V, Vasyutina E, Falcone S, Birchmeier C, Gomes ER.
|
| EMBO Rep 13(8):741-9. doi: 10.1038/embor.2012.89. Epub 2012 Jun 26.
2012
|
| 45 | CDC42, DOCK8
|
| DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses.
|
| Harada Y, Tanaka Y, Terasawa M, Pieczyk M, Habiro K, Katakai T, Hanawa-Suetsugu K, Kukimoto-Niino M, Nishizaki T, Shirouzu M, Duan X, Uruno T, Nishikimi A, Sanematsu F, Yokoyama S, Stein JV, Kinashi T, Fukui Y.
|
| Blood 119(19):4451-61. doi: 10.1182/blood-2012-01-407098. Epub 2012 Mar 28.
2012
|
| 46 | CDC42, OPHN1, RAC1, RHOA
|
| The GRAF family member oligophrenin1 is a RhoGAP with BAR domain and regulates Rho GTPases in platelets.
|
| Elvers M, Beck S, Fotinos A, Ziegler M, Gawaz M.
|
| Cardiovasc Res 94(3):526-36. doi: 10.1093/cvr/cvs079. Epub 2012 Feb 1.
2012
|
| 47 | CDC42, SYNCRIP
|
| hnRNP Q regulates Cdc42-mediated neuronal morphogenesis.
|
| Chen HH, Yu HI, Chiang WC, Lin YD, Shia BC, Tarn WY.
|
| Mol Cell Biol 32(12):2224-38. doi: 10.1128/MCB.06550-11. Epub 2012 Apr 9.
2012
|
| 48 | CD2AP, CDC42, CGNL1, SH3BP1
|
| Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex.
|
| Elbediwy A, Zihni C, Terry SJ, Clark P, Matter K, Balda MS.
|
| J Cell Biol 198(4):677-93. doi: 10.1083/jcb.201202094. Epub 2012 Aug 13.
2012
|
| 49 | CDC42, PRKCI
|
| Cdc42 controls vascular network assembly through protein kinase Cι during embryonic vasculogenesis.
|
| Qi Y, Liu J, Wu X, Brakebusch C, Leitges M, Han Y, Corbett SA, Lowry SF, Graham AM, Li S.
|
| Arterioscler Thromb Vasc Biol 31(8):1861-70. Epub 2011 Jun 9.
2011
|
| 50 | ARHGEF9, CDC42
|
| Collybistin splice variants differentially interact with gephyrin and Cdc42 to regulate gephyrin clustering at GABAergic synapses.
|
| Tyagarajan SK, Ghosh H, Harvey K, Fritschy JM.
|
| J Cell Sci 124(Pt 16):2786-96.
2011
|
| 51 | CDC42, NPC1L1
|
| The small GTPase Cdc42 interacts with Niemann-Pick C1-like 1 (NPC1L1) and controls its movement from endocytic recycling compartment to plasma membrane in a cholesterol-dependent manner.
|
| Xie C, Li N, Chen ZJ, Li BL, Song BL.
|
| J Biol Chem 286(41):35933-42. doi: 10.1074/jbc.M111.270199. Epub 2011 Aug 15.
2011
|
| 52 | CDC42
|
| Phosphatidylserine is polarized and required for proper Cdc42 localization and for development of cell polarity.
|
| Fairn GD, Hermansson M, Somerharju P, Grinstein S.
|
| Nat Cell Biol 13(12):1424-30. doi: 10.1038/ncb2351.
2011
|
| 53 | CDC42
|
| Cdc42 localization and cell polarity depend on membrane traffic.
|
| Osmani N, Peglion F, Chavrier P, Etienne-Manneville S.
|
| J Cell Biol 191(7):1261-9. Epub 2010 Dec 20.
2010
|
| 54 | CDC42, CXCR4, UBE2I
|
| Ubc9 promotes breast cell invasion and metastasis in a sumoylation-independent manner.
|
| Zhu S, Sachdeva M, Wu F, Lu Z, Mo YY.
|
| Oncogene 29(12):1763-72. doi: 10.1038/onc.2009.459. Epub 2009 Dec 21.
2010
|
| 55 | ARHGDIA, CDC42
|
| Differential phosphorylation of RhoGDI mediates the distinct cycling of Cdc42 and Rac1 to regulate second-phase insulin secretion.
|
| Wang Z, Thurmond DC.
|
| J Biol Chem 285(9):6186-97. doi: 10.1074/jbc.M109.072421. Epub 2009 Dec 22.
2010
|
| 56 | CDC42
|
| Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets.
|
| Pleines I, Eckly A, Elvers M, Hagedorn I, Eliautou S, Bender M, Wu X, Lanza F, Gachet C, Brakebusch C, Nieswandt B.
|
| Blood 115(16):3364-73. doi: 10.1182/blood-2009-09-242271. Epub 2010 Feb 4.
2010
|
| 57 | CDC42, DLG1, DLGAP1
|
| Dlg1 binds GKAP to control dynein association with microtubules, centrosome positioning, and cell polarity
|
| Manneville JB, Jehanno M, Etienne-Manneville S.
|
| J Cell Biol. Nov 1;191(3):585-98. doi: 10.1083/jcb.201002151. 2010
|
| 58 | BRSK1, BRSK2, CDC42, DCX, DOCK7, DPYSL2, GSK3A, GSK3B, IGF1, KIF13B, KIF2A, KLC1, LIS1, MAP1B, MAP2, MAPK8, MAPT, NIN, PAFAH1B1, SCG10, SCLIP, STK11, STMN1, STMN2, STMN3, STRADA
|
| Microtubule assembly, organization and dynamics in axons and dendrites.
|
| Conde C, Caceres A.
|
| Nat Rev Neurosci. 10(5):319-32. 2009
|
| 59 | CDC42, IQGAP1
|
| IQGAP1 regulates cell proliferation through a novel CDC42-mTOR pathway.
|
| Wang JB, Sonn R, Tekletsadik YK, Samorodnitsky D, Osman MA.
|
| J Cell Sci 122(Pt 12):2024-33. Epub 2009 May 19.
2009
|
| 60 | CDC42, PAK1, PAK2
|
| Dual role of Cdc42 in spindle orientation control of adherent cells.
|
| Mitsushima M, Toyoshima F, Nishida E.
|
| Mol Cell Biol 29(10):2816-27. Epub 2009 Mar 9.
2009
|
| 61 | CDC42, OBSCN, RAC1, RHOQ, TCP10
|
| TC10 controls human myofibril organization and is activated by the sarcomeric RhoGEF obscurin.
|
| Coisy-Quivy M, Touzet O, Bourret A, Hipskind RA, Mercier J, Fort P, Philips A.
|
| J Cell Sci 122(Pt 7):947-56. Epub 2009 Mar 3. 2009
|
| 62 | ARHGAP32, CDC42, GABARAP
|
| PX-RICS mediates ER-to-Golgi transport of the N-cadherin/beta-catenin complex.
|
| Nakamura T, Hayashi T, Nasu-Nishimura Y, Sakaue F, Morishita Y, Okabe T, Ohwada S, Matsuura K, Akiyama T.
|
| Genes Dev 22(9):1244-56. 2008
|
| 63 | CDC42, CDH1
|
| Cdc42 regulates E-cadherin ubiquitination and degradation through an epidermal growth factor receptor to Src-mediated pathway.
|
| Shen Y, Hirsch DS, Sasiela CA, Wu WJ.
|
| J Biol Chem 283(8):5127-37. Epub 2007 Dec 5. 2008
|
| 64 | ARHGAP1, CDC42, NDEL1
|
| Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells.
|
| Shen Y, Li N, Wu S, Zhou Y, Shan Y, Zhang Q, Ding C, Yuan Q, Zhao F, Zeng R, Zhu X.
|
| Dev Cell 14(3):342-53.
2008
|
| 65 | CDC42, DOCK10
|
| DOCK10-mediated Cdc42 activation is necessary for amoeboid invasion of melanoma cells.
|
| Gadea G, Sanz-Moreno V, Self A, Godi A, Marshall CJ.
|
| Curr Biol 18(19):1456-65. Epub 2008 Oct 2.
2008
|
| 66 | CDC42
|
| Cdc42 deficiency causes Sonic hedgehog-independent holoprosencephaly.
|
| Chen L, Liao G, Yang L, Campbell K, Nakafuku M, Kuan CY, Zheng Y.
|
| Proc Natl Acad Sci U S A 103(44):16520-5. Epub 2006 Oct 18. 2006
|
| 67 | CDC42
|
| Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin.
|
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