| 1 | CDC20, CHEK1, MAD2L1
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| Chk1 is required for the metaphase-anaphase transition via regulating the expression and localization of Cdc20 and Mad2.
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| Yang X, Xu W, Hu Z, Zhang Y, Xu N.
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| Life Sci 106(1-2):12-8. doi: 10.1016/j.lfs.2014.04.011. Epub 2014 Apr 18.
2014
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| 2 | CDC20, FBXO43
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| The zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylation.
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| Shoji S, Muto Y, Ikeda M, He F, Tsuda K, Ohsawa N, Akasaka R, Terada T, Wakiyama M, Shirouzu M, Yokoyama S.
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| FEBS Open Bio. Jul 5;4:689-703. doi: 10.1016/j.fob.2014.06.010. 2014
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| 3 | CDC20, CDH1, MAD2L2
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| Sequestration of CDH1 by MAD2L2 prevents premature APC/C activation prior to anaphase onset.
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| Listovsky T, Sale JE.
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| J Cell Biol 203(1):87-100. doi: 10.1083/jcb.201302060. Epub 2013 Oct 7.
2013
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| 4 | CDC20, PHF8
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| The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20.
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| Lim HJ, Dimova NV, Tan MK, Sigoillot FD, King RW, Shi Y.
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| Mol Cell Biol 33(21):4166-80. doi: 10.1128/MCB.00689-13. Epub 2013 Aug 26.
2013
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| 5 | CDC20, MAD2L1
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| High expression of spindle assembly checkpoint proteins CDC20 and MAD2 is associated with poor prognosis in urothelial bladder cancer.
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| Choi JW, Kim Y, Lee JH, Kim YS.
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| Virchows Arch 463(5):681-7. doi: 10.1007/s00428-013-1473-6. Epub 2013 Aug 31.
2013
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| 6 | CDC20, MAD2L1
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| Mad2 and the APC/C compete for the same site on Cdc20 to ensure proper chromosome segregation.
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| Izawa D, Pines J.
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| J Cell Biol 199(1):27-37. doi: 10.1083/jcb.201205170. Epub 2012 Sep 24.
2012
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| 7 | BUB1B, CDC20
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| Insufficiency of BUBR1, a mitotic spindle checkpoint regulator, causes impaired ciliogenesis in vertebrates.
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| Miyamoto T, Porazinski S, Wang H, Borovina A, Ciruna B, Shimizu A, Kajii T, Kikuchi A, Furutani-Seiki M, Matsuura S.
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| Hum Mol Genet 20(10):2058-70. Epub 2011 Mar 9.
2011
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| 8 | CDC20, RASSF1
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| Regulation of APC/C(Cdc20) activity by RASSF1A-APC/C(Cdc20) circuitry.
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| Chow C, Wong N, Pagano M, Lun SW, Nakayama KI, Nakayama K, Lo KW.
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| Oncogene ncogene. 2011 Aug 29. doi: 10.1038/onc.2011.372. [Epub ahead of print]
2011
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| 9 | CDC20, UBE2C
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| Spindle assembly checkpoint protein Cdc20 transcriptionally activates expression of ubiquitin carrier protein UbcH10.
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| Nath S, Banerjee T, Sen D, Das T, Roychoudhury S.
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| J Biol Chem 286(18):15666-77. Epub 2011 Mar 15.
2011
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| 10 | CDC20
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| Cdc55 coordinates spindle assembly and chromosome disjunction during meiosis.
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| Bizzari F, Marston AL.
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| J Cell Biol 193(7):1213-28. Epub 2011 Jun 20.
2011
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| 11 | CDC20, FBXW5, PLK4, SASS6
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| FBXW5 controls centrosome number.
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| Pagan J, Pagano M.
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| Nat Cell Biol 13(8):888-90. doi: 10.1038/ncb2312. 2011
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| 12 | CDC20, SP100
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| Cdc20 mediates D-box-dependent degradation of Sp100.
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| Wang R, Li KM, Zhou CH, Xue JL, Ji CN, Chen JZ.
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| Biochem Biophys Res Commun 415(4):702-6. doi: 10.1016/j.bbrc.2011.10.146. Epub 2011 Nov 6.
2011
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| 13 | CDC20
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| APC/C(Cdc20) targets E2F1 for degradation in prometaphase.
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| Peart MJ, Poyurovsky MV, Kass EM, Urist M, Verschuren EW, Summers MK, Jackson PK, Prives C.
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| Cell Cycle 9(19):3956-64. Epub 2010 Oct 26.
2010
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| 14 | CDC20
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| Cdc20 is critical for meiosis I and fertility of female mice.
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| Jin F, Hamada M, Malureanu L, Jeganathan KB, Zhou W, Morbeck DE, van Deursen JM.
|
| PLoS Genet 6(9). pii: e1001147.
2010
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| 15 | CDC20
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| Cdc20 proteolysis requires p38 MAPK signaling and Cdh1-independent APC/C ubiquitination during spindle assembly checkpoint activation by cadmium.
|
| Yen AH, Yang JL.
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| J Cell Physiol 223(2):327-34.
2010
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| 16 | CDC20, CDC27, HSF2
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| Anaphase-promoting complex/cyclosome participates in the acute response to protein-damaging stress.
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| Ahlskog JK, Björk JK, Elsing AN, Aspelin C, Kallio M, Roos-Mattjus P, Sistonen L.
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| Mol Cell Biol 30(24):5608-20. doi: 10.1128/MCB.01506-09. Epub 2010 Oct 11.
2010
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| 17 | CDC20, HDAC6
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| A centrosomal Cdc20-APC pathway controls dendrite morphogenesis in postmitotic neurons.
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| Kim AH, Puram SV, Bilimoria PM, Ikeuchi Y, Keough S, Wong M, Rowitch D, Bonni A.
|
| Cell 136(2):322-36.
2009
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| 18 | CDC20, NEUROD2
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| A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation.
|
| Yang Y, Kim AH, Yamada T, Wu B, Bilimoria PM, Ikeuchi Y, de la Iglesia N, Shen J, Bonni A.
|
| Science 326(5952):575-8.PMID: 19900895 2009
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| 19 | BUB1B, CDC20, MAD2L1
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| The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction.
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| Nilsson J, Yekezare M, Minshull J, Pines J.
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| Nat Cell Biol 10(12):1411-20. Epub 2008 Nov 9.
2008
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| 20 | CDC20
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| CDC20, a potential cancer therapeutic target, is negatively regulated by p53.
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| Kidokoro T, Tanikawa C, Furukawa Y, Katagiri T, Nakamura Y, Matsuda K.
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| Oncogene 27(11):1562-71. Epub 2007 Sep 17.PMID: 17873905 2008
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| 21 | CDC20
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| The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint.
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| Mapelli M, Massimiliano L, Santaguida S, Musacchio A.
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| Cell 131(4):730-43. 2007
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| 22 | MAD2L1, CDC20
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| A new Mad2-interacting domain of Cdc20 is critical for the function of Mad2-Cdc20 complex in the spindle assembly checkpoint.
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| Mondal G, Baral RN, Roychoudhury S.
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| Biochem J 396(2):243-53. 2006
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| 23 | BUB3, CDC20
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| WD repeat-containing mitotic checkpoint proteins act as transcriptional repressors during interphase.
|
| Yoon YM, Baek KH, Jeong SJ, Shin HJ, Ha GH, Jeon AH, Hwang SG, Chun JS, Lee CW.
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| FEBS Lett 575(1-3):23-9. 2004
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| 24 | RASSF1, CDC20, FBXO5
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| RASSF1A, the new guardian of mitosis.
|
| Mathe E.
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| Nat Genet 36(2):117-8. No abstract available. 2004
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| 25 | SPATC1, SOSTDC1, CDC20
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| Speriolin is a novel spermatogenic cell-specific centrosomal protein associated with the seventh WD motif of Cdc20.
|
| Goto M, Eddy EM.
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| J Biol Chem 279(40):42128-38. Epub 2004 Jul 26. 2004
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| 26 | CDC20, FBXO5
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| Emi1 is required for cytostatic factor arrest in vertebrate eggs.
|
| Reimann JD, Jackson PK.
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| Nature 416(6883):850-4. 2002
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| 27 | CDC20, CDH1, PTTG1
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| Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesis.
|
| Zur A, Brandeis M.
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| EMBO J 20(4):792-801. 2001
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| 28 | CDC20, FBXO5
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| Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex.
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| Reimann JD, Freed E, Hsu JY, Kramer ER, Peters JM, Jackson PK.
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| Cell 105(5):645-55. 2001
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| 29 | BUB1, BUB1B, BUB3, CDC20, MAD1L1, MAD2L1, MAD2L2, TTK
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| Characterization of MAD2B and other mitotic spindle checkpoint genes.
|
| Cahill DP, et al.
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| Genomics 58(2):181-7. 1999
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| 30 | CDC20, CDC20P
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| Genomic organization, 5' flanking enhancer region, and chromosomal assignment of the cell cycle gene, p55Cdc.
|
| Weinstein J, et al.
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| Mol Genet Metab 64 : 52-57. 1998
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| 31 | CDC20, CDC27, MAD1L1
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| Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events.
|
| Kallio M, et al.
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| J Cell Biol 141(6):1393-406. 1998
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| 32 | CDC20, FZR1
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| Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1.
|
| Fang G, Yu H, Kirschner MW.
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| Mol Cell 2(2):163-71. 1998
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| 33 | APC, CDC20, MAD1L1
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| The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation.
|
| Fang G, Yu H, Kirschner MW.
|
| Genes Dev. 12(12):1871-83. 1998
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| 34 | CDC20
|
| Cell cycle-regulated expression, phosphorylation, and degradation of p55Cdc. A mammalian homolog of CDC20/Fizzy/slp1.
|
| Weinstein J.
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| J Biol Chem 272(45):28501-11. 1997
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| 35 | CDC20
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| Over-expression of p55Cdc inhibits granulocyte differentiation and accelerates apoptosis in myeloid cells.
|
| Kao CT, et al.
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| Oncogene 13 : 1221-1229. 1996
|
| 36 | CDC20
|
| A novel mammalian protein, p55CDC, present in dividing cells is associated with protein kinase activity and has homology to the Saccharomyces cerevisiae cell division cycle proteins Cdc20 and Cdc4.
|
| Weinstein J, et al.
|
| Mol Cell Biol 14 : 3350-3363. 1994
|