| 1 | CD8A, LNX1, LNX2
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| Ligand of Numb proteins LNX1p80 and LNX2 interact with the human glycoprotein CD8α and promote its ubiquitylation and endocytosis.
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| D'Agostino M, Tornillo G, Caporaso MG, Barone MV, Ghigo E, Bonatti S, Mottola G.
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| J Cell Sci 124(Pt 21):3545-56. Epub 2011 Nov 1.
2011
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| 2 | CD8A
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| Cd8 enhancer E8I and Runx factors regulate CD8α expression in activated CD8+ T cells.
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| Hassan H, Sakaguchi S, Tenno M, Kopf A, Boucheron N, Carpenter AC, Egawa T, Taniuchi I, Ellmeier W.
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| Proc Natl Acad Sci U S A 108(45):18330-5. Epub 2011 Oct 24.
2011
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| 3 | CD8A
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| Interplay between CD8α+ dendritic cells and monocytes in response to Listeria monocytogenes infection attenuates T cell responses.
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| Kapadia D, Sadikovic A, Vanloubbeeck Y, Brockstedt D, Fong L.
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| PLoS One 6(4):e19376.
2011
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| 4 | CD8A, NFIL3
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| NFIL3/E4BP4 is a key transcription factor for CD8α⁺ dendritic cell development.
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| Kashiwada M, Pham NL, Pewe LL, Harty JT, Rothman PB.
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| Blood 117(23):6193-7. Epub 2011 Apr 7.
2011
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| 5 | CD8A, CD8B
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| Structural basis of the CD8 alpha beta/MHC class I interaction: focused recognition orients CD8 beta to a T cell proximal position.
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| Wang R, Natarajan K, Margulies DH.
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| J Immunol 183(4):2554-64. Epub 2009 Jul 22.
2009
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| 6 | CD8A
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| Gly111Ser mutation in CD8A gene causing CD8 immunodeficiency is found in Spanish Gypsies.
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| Mancebo E, Moreno-Pelayo MA, Menc’a A, de la Calle-Mart’n O, Allende LM, Sivadorai P, Kalaydjieva L, Bertranpetit J, Coto E, Calleja-Antol’n S, Ruiz-Contreras J, Paz-Artal E.
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| Mol Immunol 45(2):479-84. Epub 2007 Jul 20. 2008
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| 7 | CD8A
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| Rescue of cytotoxic function in the CD8alpha knockout mouse by removal of MHC class II.
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| Riddle DS, Miller PJ, Vincent BG, Kepler TB, Maile R, Frelinger JA, Collins EJ.
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| Eur J Immunol 38(6):1511-21.
2008
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| 8 | CD8A
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| CD40L-expressing CD8 T cells prime CD8alpha(+) DC for IL-12p70 production.
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| Wong KL, Lew FC, MacAry PA, Kemeny DM.
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| Eur J Immunol 38(8):2251-62.
2008
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| 9 | CD8A
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| CD8 alpha is expressed by human monocytes and enhances Fc gamma R-dependent responses.
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| Gibbings DJ, Marcet-Palacios M, Sekar Y, Ng MC, Befus AD.
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| BMC Immunol 8:12. 2007
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| 10 | CD8A
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| CD8 alpha coreceptor to improve TCR gene transfer to treat melanoma: down-regulation of tumor-specific production of IL-4, IL-5, and IL-10.
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| Willemsen RA, SebestyŽn Z, Ronteltap C, Berrevoets C, Drexhage J, Debets R.
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| J Immunol 177(2):991-8. Erratum in: J Immunol. 2006 Dec 15;177(12):8875-6. 2006
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| 11 | CD8A
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| CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes.
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| Garcia KC, et al.
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| Nature 384 : 577-581. 1996
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| 12 | CD8A
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| The CD8alpha locus is located on the telomere side of the immunoglobulin kappa locus at a distance of 2 Mb.
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| Weichhold GM, et al.
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| Genomics 16 : 512-514. 1993
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| 13 | CD4, CD8A
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| Characterization of cytokine gene expression in CD4+ and CD8+ T cells after activation with phorbol myristate acetate and phytohaemagglutinin.
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| Leung JC, et al.
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| Clin Exp Immunol 90 : 147-153. 1992
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| 14 | CD8A
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| Dinucleotide repeat polymorphism at the human MHC class I CD8 alpha-chain (LEU-2/T8) gene.
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| Polymeropoulos MH, et al.
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| Nucleic Acids Res 19 : 1718. 1991
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| 15 | CD8A, GYPC, CRYG@, CRYGB, CRYGC, CRYGFP, CRYGP1, CRYGP2, MAP2
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| Assignment of MAP2 to chromosome 2 and other extensions of the genetic linkage map on chromosome in non-CEPH families.
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| Pakstis AJ, et al.
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| Am J Hum Genet 47 : A193. 1990
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| 16 | CD8A
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| Gene for the human T-cell differentiation antigen Leu-2/T8 is closely linked to the kappa light chain locus on chromosome 2.
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| Sukhatme VP, et al.
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| J Exp Med 161 : 429-434. 1985
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| 17 | CD8A
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| The human T cell antigen Leu-2 (T8) is encoded on chromosome 2.
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| Bruns G, et al.
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| Hum Genet 70 : 311-314. 1985
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| 18 | CD8A
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| Isolation of the gene encoding the human T-lymphocyte differentiation antigen LEU-2 (T8) by gene transfer and cDNA subtraction.
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| Kavathas P, et al.
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| Proc Natl Acad Sci U S A 81 : 7688-7692. 1984
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