Citations for
Ligand of Numb proteins LNX1p80 and LNX2 interact with the human glycoprotein CD8α and promote its ubiquitylation and endocytosis.
D'Agostino M, Tornillo G, Caporaso MG, Barone MV, Ghigo E, Bonatti S, Mottola G.
J Cell Sci 124(Pt 21):3545-56. Epub 2011 Nov 1. 2011
Cd8 enhancer E8I and Runx factors regulate CD8α expression in activated CD8+ T cells.
Hassan H, Sakaguchi S, Tenno M, Kopf A, Boucheron N, Carpenter AC, Egawa T, Taniuchi I, Ellmeier W.
Proc Natl Acad Sci U S A 108(45):18330-5. Epub 2011 Oct 24. 2011
Interplay between CD8α+ dendritic cells and monocytes in response to Listeria monocytogenes infection attenuates T cell responses.
Kapadia D, Sadikovic A, Vanloubbeeck Y, Brockstedt D, Fong L.
PLoS One 6(4):e19376. 2011
NFIL3/E4BP4 is a key transcription factor for CD8α⁺ dendritic cell development.
Kashiwada M, Pham NL, Pewe LL, Harty JT, Rothman PB.
Blood 117(23):6193-7. Epub 2011 Apr 7. 2011
Structural basis of the CD8 alpha beta/MHC class I interaction: focused recognition orients CD8 beta to a T cell proximal position.
Wang R, Natarajan K, Margulies DH.
J Immunol 183(4):2554-64. Epub 2009 Jul 22. 2009
Gly111Ser mutation in CD8A gene causing CD8 immunodeficiency is found in Spanish Gypsies.
Mancebo E, Moreno-Pelayo MA, Mencía A, de la Calle-Martín O, Allende LM, Sivadorai P, Kalaydjieva L, Bertranpetit J, Coto E, Calleja-Antolín S, Ruiz-Contreras J, Paz-Artal E.
Mol Immunol 45(2):479-84. Epub 2007 Jul 20. 2008
Rescue of cytotoxic function in the CD8alpha knockout mouse by removal of MHC class II.
Riddle DS, Miller PJ, Vincent BG, Kepler TB, Maile R, Frelinger JA, Collins EJ.
Eur J Immunol 38(6):1511-21. 2008
CD40L-expressing CD8 T cells prime CD8alpha(+) DC for IL-12p70 production.
Wong KL, Lew FC, MacAry PA, Kemeny DM.
Eur J Immunol 38(8):2251-62. 2008
CD8 alpha is expressed by human monocytes and enhances Fc gamma R-dependent responses.
Gibbings DJ, Marcet-Palacios M, Sekar Y, Ng MC, Befus AD.
BMC Immunol 8:12. 2007
CD8 alpha coreceptor to improve TCR gene transfer to treat melanoma: down-regulation of tumor-specific production of IL-4, IL-5, and IL-10.
Willemsen RA, Sebestyén Z, Ronteltap C, Berrevoets C, Drexhage J, Debets R.
J Immunol 177(2):991-8. Erratum in: J Immunol. 2006 Dec 15;177(12):8875-6. 2006
CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes.
Garcia KC, et al.
Nature 384 : 577-581. 1996
The CD8alpha locus is located on the telomere side of the immunoglobulin kappa locus at a distance of 2 Mb.
Weichhold GM, et al.
Genomics 16 : 512-514. 1993
13CD4, CD8A
Characterization of cytokine gene expression in CD4+ and CD8+ T cells after activation with phorbol myristate acetate and phytohaemagglutinin.
Leung JC, et al.
Clin Exp Immunol 90 : 147-153. 1992
Dinucleotide repeat polymorphism at the human MHC class I CD8 alpha-chain (LEU-2/T8) gene.
Polymeropoulos MH, et al.
Nucleic Acids Res 19 : 1718. 1991
Assignment of MAP2 to chromosome 2 and other extensions of the genetic linkage map on chromosome in non-CEPH families.
Pakstis AJ, et al.
Am J Hum Genet 47 : A193. 1990
Gene for the human T-cell differentiation antigen Leu-2/T8 is closely linked to the kappa light chain locus on chromosome 2.
Sukhatme VP, et al.
J Exp Med 161 : 429-434. 1985
The human T cell antigen Leu-2 (T8) is encoded on chromosome 2.
Bruns G, et al.
Hum Genet 70 : 311-314. 1985
Isolation of the gene encoding the human T-lymphocyte differentiation antigen LEU-2 (T8) by gene transfer and cDNA subtraction.
Kavathas P, et al.
Proc Natl Acad Sci U S A 81 : 7688-7692. 1984