Citations for
1CD1D, CD86
Decreased CD1d level is associated with CD86 over-expression in B cells from systemic lupus erythematosus.
Liu F, Ji J, Li X, Li X, Xu J, Yue H, Zhao S, Fan H, Hou Y.
Acta Biochim Biophys Sin (Shanghai) 49(4):328-337. doi: 10.1093/abbs/gmx011. 2017
2CD86
IL-10-produced by human transitional B-cells down-regulates CD86 expression on B-cells leading to inhibition of CD4+T-cell responses.
Nova-Lamperti E, Fanelli G, Becker PD, Chana P, Elgueta R, Dodd PC, Lord GM, Lombardi G, Hernandez-Fuentes MP.
Sci Rep 6:20044. doi: 10.1038/srep20044. 2016
3CD86, DEF103B, P2RX7
Human β Defensin-3 Increases CD86 Expression on Monocytes by Activating the ATP-Gated Channel P2X7.
Lioi AB, Ferrari BM, Dubyak GR, Weinberg A, Sieg SF.
J Immunol 195(9):4438-45. doi: 10.4049/jimmunol.1401319. Epub 2015 Sep 28. 2015
4CD80, CD86
CD80 and CD86 IgC domains are important for quaternary structure, receptor binding and co-signaling function.
Girard T, Gaucher D, El-Far M, Breton G, Sékaly RP.
Immunol Lett 161(1):65-75. doi: 10.1016/j.imlet.2014.05.002. Epub 2014 May 15. 2014
5CD86, IL21
IL-21 promotes CD4 T cell responses by phosphatidylinositol 3-kinase-dependent upregulation of CD86 on B cells.
Attridge K, Kenefeck R, Wardzinski L, Qureshi OS, Wang CJ, Manzotti C, Okkenhaug K, Walker LS.
J Immunol 192(5):2195-201. doi: 10.4049/jimmunol.1302082. Epub 2014 Jan 27. 2014
6CD80, CD86, IL6
Novel regulation of CD80/CD86-induced phosphatidylinositol 3-kinase signaling by NOTCH1 protein in interleukin-6 and indoleamine 2,3-dioxygenase production by dendritic cells.
Koorella C, Nair JR, Murray ME, Carlson LM, Watkins SK, Lee KP.
J Biol Chem 289(11):7747-62. doi: 10.1074/jbc.M113.519686. Epub 2014 Jan 10. 2014
7CD80, CD86
Differential DNA methylation patterns in the CD86 gene controls its constitutive expression in keratinocytes.
Romero-Tlalolini MA, Chávez Olmos P, Garrido E.
Biochem Biophys Res Commun 438(1):54-60. doi: 10.1016/j.bbrc.2013.07.023. Epub 2013 Jul 16. 2013
8CD86, IGHG1, PHB, PHB2
Prohibitins and the cytoplasmic domain of CD86 cooperate to mediate CD86 signaling in B lymphocytes.
Lucas CR, Cordero-Nieves HM, Erbe RS, McAlees JW, Bhatia S, Hodes RJ, Campbell KS, Sanders VM.
J Immunol 190(2):723-36. doi: 10.4049/jimmunol.1201646. Epub 2012 Dec 12. 2013
9CD86
A conserved polylysine motif in CD86 cytoplasmic tail is necessary for cytoskeletal association and effective co-stimulation.
Girard T, El-Far M, Gaucher D, Acuto O, Beaulé G, Michel F, Mourad W, Sékaly RP.
Biochem Biophys Res Commun 423(2):301-7. doi: 10.1016/j.bbrc.2012.05.116. Epub 2012 May 30. 2012
10CD86, IL2, NFATC1
IL-2 upregulates CD86 expression on human CD4(+) and CD8(+) T cells.
Paine A, Kirchner H, Immenschuh S, Oelke M, Blasczyk R, Eiz-Vesper B.
J Immunol 188(4):1620-9. doi: 10.4049/jimmunol.1100181. Epub 2012 Jan 13. 2012
11CD86, MARCH1
Ubiquitination of CD86 is a key mechanism in regulating antigen presentation by dendritic cells.
Baravalle G, Park H, McSweeney M, Ohmura-Hoshino M, Matsuki Y, Ishido S, Shin JS.
J Immunol 187(6):2966-73. Epub 2011 Aug 17. 2011
12CD86, MARCH1
Ubiquitin-mediated regulation of CD86 protein expression by the ubiquitin ligase membrane-associated RING-CH-1 (MARCH1).
Corcoran K, Jabbour M, Bhagwandin C, Deymier MJ, Theisen DL, Lybarger L.
J Biol Chem 286(43):37168-80. doi: 10.1074/jbc.M110.204040. Epub 2011 Sep 6. 2011
13CD80, CD86, SPI1
Critical role of transcription factor PU.1 in the expression of CD80 and CD86 on dendritic cells.
Kanada S, Nishiyama C, Nakano N, Suzuki R, Maeda K, Hara M, Kitamura N, Ogawa H, Okumura K.
Blood 117(7):2211-22. doi: 10.1182/blood-2010-06-291898. Epub 2010 Nov 30. 2011
14CD80, CD86
B7-1/2 (CD80/CD86) direct signaling to B cells enhances IgG secretion.
Rau FC, Dieter J, Luo Z, Priest SO, Baumgarth N.
J Immunol 183(12):7661-71. doi: 10.4049/jimmunol.0803783. 2009
15CD86
Expression of CD86 on human islet endothelial cells facilitates T cell adhesion and migration.
Lozanoska-Ochser B, Klein NJ, Huang GC, Alvarez RA, Peakman M.
J Immunol 181(9):6109-16. 2008
16CD86
Expression of the costimulatory molecule CD86, but not CD80, in keratinocytes of normal cervical epithelium and human papillomavirus-16 positive low squamous intraepithelial lesions.
Ortiz-Sanchez E, Chavez-Olmos P, Pina-Sanchez P, Salcedo M, Garrido E.
Int J Gynecol Cancer 17(3):571-80. Epub 2007 Mar 26. 2007
17CD86
A functional CD86 polymorphism associated with asthma and related allergic disorders.
Corydon TJ, Haagerup A, Jensen TG, Binderup HG, Petersen MS, Kaltoft K, Vestbo J, Kruse TA, Borglum AD.
J Med Genet 44(8):509-15. Epub 2007 May 18. 2007
18CD28, CD86
Ligation of CD28 by its natural ligand CD86 in the absence of TCR stimulation induces lipid raft polarization in human CD4 T cells.
Kovacs B, Parry RV, Ma Z, Fan E, Shivers DK, Freiberg BA, Thomas AK, Rutherford R, Rumbley CA, Riley JL, Finkel TH.
J Immunol 175(12):7848-54. 2005
19CD86, CD80
CD86 and CD80 differentially modulate the suppressive function of human regulatory T cells.
Zheng Y, Manzotti CN, Liu M, Burke F, Mead KI, Sansom DM.
J Immunol 172(5):2778-84. 2004
20CD86, CTLA4
Structural basis for co-stimulation by the human CTLA-4/B7-2 complex.
Schwartz JC, Zhang X, Fedorov AA, Nathenson SG, Almo SC.
Nature 410(6828):604-608. 2001
21CD86
Identification of an alternatively spliced variant of human CD86 mRNA.
Magistrelli G, Caron G, Gauchat JF, Jeannin P, Bonnefoy JY, Delneste Y.
Biochem Biophys Res Commun 280(5):1211-5. 2001
22CD86
Soluble CD86 is a costimulatory molecule for human T lymphocytes.
Jeannin P, Magistrelli G, Aubry JP, Caron G, Gauchat JF, Renno T, Herbault N, Goetsch L, Blaecke A, Dietrich PY, Bonnefoy JY, Delneste Y.
Immunity 13(3):303-12. 2000
23CD86
Cloning and functional characterization of the 5'-regulatory region of the human CD86 gene.
Li J, Colovai AI, Cortesini R, Suciu-Foca N.
Hum Immunol 61(5):486-98. 2000
24CD80, CD86
The costimulatory genes Cd80 and Cd86 are linked on mouse chromosome 16 and human chromosome 3.
Reeves RH, Patch D, Sharpe AH, Borriello F, Freeman GJ, Edelhoff S, Disteche C.
Mamm Genome 8(8):581-2. 1997
25CD80, CD86
CD28/CTLA-4 ligands : the gene encoding CD86 (B70/B7.2) maps to the same region as CD80 (B7/B7.1) gene in human chromosome 3q13-q23.
Fernandez-Ruiz E, et al.
Eur J Immunol 25 : 1453-1456. 1995
26CD86
Genomic organization of the gene coding for the costimulatory human B-lymphocyte antigen B7-2 (CD86).
Jellis CL, Wang SS, Rennert P, Borriello F, Sharpe AH, Green NR, Gray GS.
Immunogenetics 42(2):85-9. 1995
27CD80, CD86, CTLA4
CTLA-4 is a second receptor for the B cell activation antigen B7.
Linsley PS, et al.
J Exp Med 174(3):561-9. 1991