1 | CD82, PPFIA1
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| Liprin-α1 modulates cancer cell signaling by transmembrane protein CD82 in adhesive membrane domains linked to cytoskeleton.
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| Pehkonen H, Lento M, von Nandelstadh P, Filippou A, Grénman R, Lehti K, Monni O.
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| Cell Commun Signal. Jul 13;16(1):41. doi: 10.1186/s12964-018-0253-y. 2018
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2 | CD82, KISS1
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| Immunohistochemical expression pattern of metastasis suppressors KAI1 and KISS1 in endometriosis and normal endometrium.
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| Timologou A, Zafrakas M, Grimbizis G, Miliaras D, Kotronis K, Stamatopoulos P, Tarlatzis BC.
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| Eur J Obstet Gynecol Reprod Biol 199:110-5. doi: 10.1016/j.ejogrb.2016.02.004. Epub 2016 Feb 16.
2016
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3 | CD82, CDH2
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| Tetraspanin CD82 regulates bone marrow homing of acute myeloid leukemia by modulating the molecular organization of N-cadherin.
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| Marjon KD, Termini CM, Karlen KL, Saito-Reis C, Soria CE, Lidke KA, Gillette JM.
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| Oncogene 35(31):4132-40. doi: 10.1038/onc.2015.449. Epub 2015 Nov 23.
2016
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4 | AKT1, BCL2L12, CD82, STAT5A
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| The novel function of CD82 and its impact on BCL2L12 via AKT/STAT5 signal pathway in acute myelogenous leukemia cells.
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| Nishioka C, Ikezoe T, Takeuchi A, Nobumoto A, Tsuda M, Yokoyama A.
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| Leukemia 29(12):2296-306. doi: 10.1038/leu.2015.219. Epub 2015 Aug 11.
2015
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5 | CD82
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| Metastasis suppressor tetraspanin CD82/KAI1 regulates ubiquitylation of epidermal growth factor receptor.
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| Odintsova E, van Niel G, Conjeaud H, Raposo G, Iwamoto R, Mekada E, Berditchevski F.
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| J Biol Chem 288(36):26323-34. doi: 10.1074/jbc.M112.439380. Epub 2013 Jul 29.
2013
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6 | CD82
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| Metastasis suppressor KAI1/CD82 attenuates the matrix adhesion of human prostate cancer cells by suppressing fibronectin expression and β1 integrin activation.
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| Lee HA, Park I, Byun HJ, Jeoung D, Kim YM, Lee H.
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| Cell Physiol Biochem 27(5):575-86. Epub 2011 Jun 15.
2011
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7 | CD82
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| Overexpression of KAI1 induces autophagy and increases MiaPaCa-2 cell survival through the phosphorylation of extracellular signal-regulated kinases.
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| Wu CY, Yan J, Yang YF, Xiao FJ, Li QF, Zhang QW, Wang LS, Guo XZ, Wang H.
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| Biochem Biophys Res Commun 404(3):802-8. Epub 2010 Dec 17.
2011
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8 | CD82, EPAS1
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| HIF-2 directly activates CD82 gene expression in endothelial cells.
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| Nagao K, Oka K.
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| Biochem Biophys Res Commun 407(1):260-5. Epub 2011 Mar 5.
2011
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9 | ATF3, CD82, NDRG1
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| KAI1 gene is engaged in NDRG1 gene-mediated metastasis suppression through the ATF3-NFkappaB complex in human prostate cancer.
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| Liu W, Iiizumi-Gairani M, Okuda H, Kobayashi A, Watabe M, Pai SK, Pandey PR, Xing F, Fukuda K, Modur V, Hirota S, Suzuki K, Chiba T, Endo M, Sugai T, Watabe K.
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| J Biol Chem 286(21):18949-59. Epub 2011 Mar 21. 2011
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10 | CD82
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| Identification of the KAI1 metastasis suppressor gene as a hypoxia target gene.
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| Kim B, Boo K, Lee JS, Kim KI, Kim WH, Cho HJ, Park YB, Kim HS, Baek SH.
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| Biochem Biophys Res Commun 393(1):179-84. Epub 2010 Feb 1.
2010
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11 | AMFR, CD82
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| A role for KAI1 in promotion of cell proliferation and mammary gland hyperplasia by the gp78 ubiquitin ligase.
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| Joshi B, Li L, Nabi IR.
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| J Biol Chem 285(12):8830-9. doi: 10.1074/jbc.M109.074344. Epub 2010 Jan 20.
2010
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12 | CD82
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| CD82 endocytosis and cholesterol-dependent reorganization of tetraspanin webs and lipid rafts.
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| Xu C, Zhang YH, Thangavel M, Richardson MM, Liu L, Zhou B, Zheng Y, Ostrom RS, Zhang XA.
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| FASEB J 23(10):3273-88. Epub 2009 Jun 4.
2009
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13 | CD82
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| Decreased expression of KAI1/CD82 metastasis suppressor gene is associated with loss of heterozygosity in melanoma cell lines.
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| Kim YI, Shin MK, Lee JW, Chung JH, Lee MH.
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| Oncol Rep 21(1):159-64.
2009
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14 | CD82
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| Regulation of c-Met signaling by the tetraspanin KAI-1/CD82 affects cancer cell migration.
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| Takahashi M, Sugiura T, Abe M, Ishii K, Shirasuna K.
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| Int J Cancer 121(9):1919-29.
2007
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15 | ACKR1, CD82
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| Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression.
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| Bandyopadhyay S, Zhan R, Chaudhuri A, Watabe M, Pai SK, Hirota S, Hosobe S, Tsukada T, Miura K, Takano Y, Saito K, Pauza ME, Hayashi S, Wang Y, Mohinta S, Mashimo T, Iiizumi M, Furuta E, Watabe K.
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| Nat Med 12(8):933-8. Epub 2006 Jul 23. 2006
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16 | CD82
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| KAI1/CD82 suppresses tumor invasion by MMP9 inactivation via TIMP1 up-regulation in the H1299 human lung carcinoma cell line.
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| Jee BK, Park KM, Surendran S, Lee WK, Han CW, Kim YS, Lim Y.
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| Biochem Biophys Res Commun 342(2):655-61. Epub 2006 Feb 8. 2006
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17 | CD82
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| CD82 metastasis suppressor gene: a potential target for new therapeutics?
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| Tonoli H, Barrett JC.
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| Trends Mol Med 11(12):563-70. Epub 2005 Nov 3. Review. 2005
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18 | VANGL1, CD82
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| KAI1 COOH-terminal interacting tetraspanin (KITENIN), a member of the tetraspanin family, interacts with KAI1, a tumor metastasis suppressor, and enhances metastasis of cancer.
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| Lee JH, Park SR, Chay KO, Seo YW, Kook H, Ahn KY, Kim YJ, Kim KK.
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| Cancer Res 64(12):4235-43. 2004
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19 | CD82, TSG11G
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| Identification of candidate liver tumor suppressor genes from human 11p11.2-p12.
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| Ricketts SL, Garcia NF, Betz BL, Coleman WB.
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| Genes Chromosomes Cancer 33(1):47-59. 2002
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20 | CD82
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| KAI1 metastasis suppressor gene is frequently down-regulated in cervical carcinoma.
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| Liu FS, Chen JT, Dong JT, Hsieh YT, Lin AJ, Ho ES, Hung MJ, Lu CH.
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| Am J Pathol 159(5):1629-34. 2001
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21 | CD82
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| Down-regulation of KAI1 messenger RNA expression is not associated with loss of heterozygosity of the KAI1 gene region in lung adenocarcinoma.
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| Tagawa K, Arihiro K, Takeshima Y, Hiyama E, Yamasaki M, Inai K.
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| Jpn J Cancer Res 90(9):970-6 1999
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22 | CD82
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| Overexpression of CD82 on human T cells enhances LFA-1 / ICAM-1-mediated cell-cell adhesion: functional association between CD82 and LFA-1 in T cell activation.
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| Shibagaki N, Hanada Ki, Yamashita H, Shimada S, Hamada H.
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| Eur J Immunol 29(12):4081-91. 1999
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23 | CD82
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| Loss of KAI1 expression in the progression of colorectal cancer.
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| Lombardi DP, Geradts J, Foley JF, Chiao C, Lamb PW, Barrett JC.
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| Cancer Res 59(22):5724-31. 1999
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24 | CD82, TP53
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| The expression of the KAI1 gene, a tumor metastasis suppressor, is directly activated by p53.
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| Mashimo T, et al.
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| Proc Natl Acad Sci U S A 95 : 11307-11311. 1998
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25 | CD9, CD19, CD81, CD82
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| CD19 is linked to the integrin-associated tetraspans CD9, CD81, and CD82.
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| Horvath G, Serru V, Clay D, Billard M, Boucheix C, Rubinstein E.
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| J Biol Chem 273 : 30537-30543. 1998
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26 | CD82
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| KAI1, a new metastasis suppressor gene, is reduced in metastatic hepatocellular carcinoma.
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| Guo XZ, et al.
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| Hepatology 28 : 1481-1488. 1998
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27 | FOLH1, CD82, TSG11A
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| Detailed genetic mapping around a putative prostate-specific membrane antigen locus on human chromosome 11p11.2.
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| Maraj BH, Leek JP, Karayi M, Ali M, Lench NJ, Markham AF.
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| Cytogenet Cell Genet 81(1):3-9. 1998
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28 | CD82
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| Genomic organization of the human KAI1 metastasis-suppressor gene.
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| Dong JT, et al.
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| Genomics 41 : 25-32. 1997
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29 | CD82
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| KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2.
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| Dong JT, et al.
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| Science 268 : 884-886. 1995
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30 | CD37, CD53, CD82
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| The genes for CD53 CD37, and R2LSA, all members of a novel gene family, are located on different chromosomes.
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| Virtaneva KI, et al.
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| Immunogenetics 37 : 461-465. 1993
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31 | CD82, PCMS
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| Localization of metastasis suppressor gene(s) for prostatic cancer to the short arm of human chromosome 11.
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| Ichikawa T, et al.
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| Cancer Res 52 : 3486-3490. 1992
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