| 1 | CD81, MMP14
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| The tetraspanin CD81 protein increases melanoma cell motility by up-regulating metalloproteinase MT1-MMP expression through the pro-oncogenic Akt-dependent Sp1 activation signaling pathways.
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| Hong IK, Byun HJ, Lee J, Jin YJ, Wang SJ, Jeoung DI, Kim YM, Lee H.
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| J Biol Chem 289(22):15691-704. doi: 10.1074/jbc.M113.534206. Epub 2014 Apr 14.
2014
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| 2 | CD81
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| A role for CD81 and hepatitis C virus in hepatoma mobility.
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| Brimacombe CL, Wilson GK, Hübscher SG, McKeating JA, Farquhar MJ.
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| Viruses 6(3):1454-72. doi: 10.3390/v6031454.
2014
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| 3 | CD81
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| CD81 controls sustained T cell activation signaling and defines the maturation stages of cognate immunological synapses.
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| Rocha-Perugini V, Zamai M, González-Granado JM, Barreiro O, Tejera E, Yañez-Mó M, Caiolfa VR, Sanchez-Madrid F.
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| Mol Cell Biol 33(18):3644-58. doi: 10.1128/MCB.00302-13. Epub 2013 Jul 15.
2013
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| 4 | CD81, GPC3, HHEX
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| Regulation of liver growth by glypican 3, CD81, hedgehog, and Hhex.
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| Bhave VS, Mars W, Donthamsetty S, Zhang X, Tan L, Luo J, Bowen WC, Michalopoulos GK.
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| Am J Pathol 183(1):153-9. doi: 10.1016/j.ajpath.2013.03.013. Epub 2013 May 8.
2013
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| 5 | CD81, CD9
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| Normal muscle regeneration requires tight control of muscle cell fusion by tetraspanins CD9 and CD81.
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| Charrin S, Latil M, Soave S, Polesskaya A, Chrétien F, Boucheix C, Rubinstein E.
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| Nat Commun 4:1674. doi: 10.1038/ncomms2675.
2013
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| 6 | CD81
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| CD81 regulates cell migration through its association with Rac GTPase.
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| Tejera E, Rocha-Perugini V, López-Martín S, Pérez-Hernández D, Bachir AI, Horwitz AR, Vázquez J, Sánchez-Madrid F, Yáñez-Mo M.
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| Mol Biol Cell 24(3):261-73. doi: 10.1091/mbc.E12-09-0642. Epub 2012 Dec 21.
2013
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| 7 | CD81
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| CD81 interacts with the T cell receptor to suppress signaling.
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| Cevik SI, Keskin N, Belkaya S, Ozlu MI, Deniz E, Tazebay UH, Erman B.
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| PLoS One 7(11):e50396. doi: 10.1371/journal.pone.0050396. Epub 2012 Nov 30.
2012
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| 8 | CD81
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| In silico directed mutagenesis identifies the CD81/claudin-1 hepatitis C virus receptor interface.
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| Davis C, Harris HJ, Hu K, Drummer HE, McKeating JA, Mullins JG, Balfe P.
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| Cell Microbiol 14(12):1892-903. doi: 10.1111/cmi.12008. Epub 2012 Sep 25.
2012
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| 9 | CD81, FKBP11, IFITM1, IFITM2, IFITM3, IFITM5, PTGFRN
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| Osteoblast-enriched membrane protein IFITM5 regulates the association of CD9 with an FKBP11-CD81-FPRP complex and stimulates expression of interferon-induced genes.
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| Hanagata N, Li X.
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| Biochem Biophys Res Commun 409(3):378-84. Epub 2011 May 11.
2011
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| 10 | CD81
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| CD81 is essential for the formation of membrane protrusions and regulates Rac1-activation in adhesion-dependent immune cell migration.
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| Quast T, Eppler F, Semmling V, Schild C, Homsi Y, Levy S, Lang T, Kurts C, Kolanus W.
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| Blood 118(7):1818-27. Epub 2011 Jun 15.
2011
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| 11 | CD19, CD81, CVID6
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| CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency.
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| van Zelm MC, Smet J, Adams B, Mascart F, Schandené L, Janssen F, Ferster A, Kuo CC, Levy S, van Dongen JJ, van der Burg M.
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| J Clin Invest 120(4):1265-74. doi: 10.1172/JCI39748. Epub 2010 Mar 8. 2010
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| 12 | BCAP31, CD44, CD81, MARCHF4, MARCHF8
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| Membrane-Associated RING-CH proteins associate with Bap31 and target CD81 and CD44 to lysosomes.
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| Bartee E, Eyster CA, Viswanathan K, Mansouri M, Donaldson JG, Früh K.
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| PLoS One 5(12):e15132. 2010
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| 13 | CD63, CD81, CD9
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| Distinct roles for tetraspanins CD9, CD63 and CD81 in the formation of multinucleated giant cells.
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| Parthasarathy V, Martin F, Higginbottom A, Murray H, Moseley GW, Read RC, Mal G, Hulme R, Monk PN, Partridge LJ.
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| Immunology 127(2):237-48.PMID: 19489128 2009
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| 14 | ADI1, CD81
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| 293 cells over-expressing human ADI1 and CD81 are permissive for serum-derived hepatitis C virus infection.
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| Cheng JC, Yeh YJ, Pai LM, Chang ML, Yeh CT.
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| J Med Virol 81(9):1560-8.
2009
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| 15 | CD151, CD81, RNF128
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| The single subunit transmembrane E3 ligase gene related to anergy in lymphocytes (GRAIL) captures and then ubiquitinates transmembrane proteins across the cell membrane.
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| Lineberry N, Su L, Soares L, Fathman CG.
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| J Biol Chem 283(42):28497-505. Epub 2008 Aug 18.
2008
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| 16 | CD9, CD19, CD81, CD82
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| CD19 is linked to the integrin-associated tetraspans CD9, CD81, and CD82.
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| Horvath G, Serru V, Clay D, Billard M, Boucheix C, Rubinstein E.
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| J Biol Chem 273 : 30537-30543. 1998
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| 17 | CD81, ST5
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| A 1-Mb physical map and PAC contig of the imprinted domain in 11p15.5 that contains TAPA1 and the BWSCR1/WT2 region.
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| Reid LH, Davies C, Cooper PR, Crider-Miller SJ, Sait SN, Nowak NJ, Evans G, Stanbridge EJ, deJong P, Shows TB, Weissman BE, Higgins MJ.
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| Genomics 43(3):366-75. 1997
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| 18 | ASCL2, BWS, CDKN1C, PHLDA2, KCNQ1, TSSC2, CD81, ST5, TSSC1
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| A 2.5-Mb transcript map of a tumor-suppressing subchromosomal transferable fragment from 11p15.5, and isolation and sequence analysis of three novel genes.
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| Hu RJ, Lee MP, Connors TD, Johnson LA, Burn TC, Su K, Landes GM, Feinberg AP.
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| Genomics 46(1):9-17. 1997
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| 19 | TSPAN7, TM4SF1, CD81
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| Chromosomal localization of three human genes coding for A15, L6, and S5.7(TAPA1) : all members of the transmembrane 4 superfamily of proteins.
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| Virtaneva KI, et al.
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| Immunogenetics 39 : 329-334. 1994
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| 20 | CD81
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| Genomic organization and chromosomal localization of the TAPA-1 gene.
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| Andria ML, et al.
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| J Immunol 147 : 1030-1036. 1991
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