| 1 | CARMIL2, CD28
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| The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells.
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| Roncagalli R, Cucchetti M, Jarmuzynski N, Grégoire C, Bergot E, Audebert S, Baudelet E, Menoita MG, Joachim A, Durand S, Suchanek M, Fiore F, Zhang L, Liang Y, Camoin L, Malissen M, Malissen B.
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| J Exp Med. Oct 17;213(11):2437-2457. doi: 10.1084/jem.20160579. Epub 2016 Sep 19. 2016
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| 2 | BCL2L14, CD28, CD3D, FAU
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| Ubiquitin-like protein MNSFβ negatively regulates T cell function and survival.
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| Nakamura M, Nakagawa M, Watanabe J.
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| Immunol Invest 44(1):1-12. doi: 10.3109/08820139.2014.909454. Epub 2014 Sep 2.
2015
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| 3 | CD28, NDFIP1
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| Ndfip1 enforces a requirement for CD28 costimulation by limiting IL-2 production.
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| Ramos-Hernández N, Ramon HE, Beal AM, Laroche A, Dekleva EA, Oliver PM.
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| J Immunol 191(4):1536-46. doi: 10.4049/jimmunol.1203571. Epub 2013 Jul 12.
2013
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| 4 | CD28, HNRNPLL
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| CD28 costimulation regulates genome-wide effects on alternative splicing.
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| Butte MJ, Lee SJ, Jesneck J, Keir ME, Haining WN, Sharpe AH.
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| PLoS One 7(6):e40032. doi: 10.1371/journal.pone.0040032. Epub 2012 Jun 29.
2012
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| 5 | CD28, ICOS
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| CD28 and ICOS play complementary non-overlapping roles in the development of Th2 immunity in vivo.
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| Shilling RA, Clay BS, Tesciuba AG, Berry EL, Lu T, Moore TV, Bandukwala HS, Tong J, Weinstock JV, Flavell RA, Horan T, Yoshinaga SK, Welcher AA, Cannon JL, Sperling AI.
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| Cell Immunol 259(2):177-84. Epub 2009 Jul 10.
2009
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| 6 | CD28, CTLA4, ICOS
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| Signatures of strong population differentiation shape extended haplotypes across the human CD28, CTLA4, and ICOS costimulatory genes.
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| Butty V, Roy M, Sabeti P, Besse W, Benoist C, Mathis D.
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| Proc Natl Acad Sci U S A 104(2):570-5. Epub 2006 Dec 29. 2007
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| 7 | CTLA4, CD28
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| Expression of CD28 and cytotoxic T lymphocyte antigen 4 at the maternal-fetal interface in women with unexplained pregnancy loss.
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| Wang X, Ma Z, Hong Y, Lu P, Lin Q.
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| Int J Gynaecol Obstet 93(2):123-9. Epub 2006 Mar 6. 2006
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| 8 | CD28, CTLA4, ICOS
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| Genetic analysis of the 2q33 region containing CD28-CTLA4-ICOS genes: association with non-Hodgkin's lymphoma.
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| Piras G, Monne M, Uras A, Palmas A, Murineddu M, Arru L, Bianchi A, Calvisi A, Curreli L, Gaviano E, Lai P, Murgia A, Latte GC, Noli A, Gabbas A.
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| Br J Haematol 129(6):784-90. 2005
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| 9 | CD28, CD86
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| Ligation of CD28 by its natural ligand CD86 in the absence of TCR stimulation induces lipid raft polarization in human CD4 T cells.
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| Kovacs B, Parry RV, Ma Z, Fan E, Shivers DK, Freiberg BA, Thomas AK, Rutherford R, Rumbley CA, Riley JL, Finkel TH.
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| J Immunol 175(12):7848-54. 2005
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| 10 | HSH2D, CD28
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| Cloning and characterization of ALX, an adaptor downstream of CD28.
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| Greene TA, Powell P, Nzerem C, Shapiro MJ, Shapiro VS.
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| J Biol Chem 278(46):45128-34. Epub 2003 Sep 5. 2003
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| 11 | CD28, CTLA4
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| CTLA-4/CD28 gene region is associated with genetic susceptibility to coeliac disease in UK families.
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| King AL, Moodie SJ, Fraser JS, Curtis D, Reid E, Dearlove AM, Ellis HJ, Ciclitira PJ.
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| J Med Genet 39(1):51-4. No abstract available. 2002
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| 12 | CD28, PRKCQ
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| CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse.
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| Huang J, Lo PF, Zal T, Gascoigne NR, Smith BA, Levin SD, Grey HM.
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| Proc Natl Acad Sci U S A 99(14):9369-73. 2002
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| 13 | CD28, CTLA4
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| Variation in the CTLA4/CD28 gene region confers an increased risk of coeliac disease.
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| Popat S, Hearle N, Hogberg L, Braegger CP, O'Donoghue D, Falth-Magnusson K, Holmes GK, Howdle PD, Jenkins H, Johnston S, Kennedy NP, Kumar PJ, Logan RF, Marsh MN, Mulder CJ, Torinsson Naluai A, Sjoberg K, Stenhammar L, Walters JR, Jewell DP, Houlston RS.
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| Ann Hum Genet 66(Pt 2):125-37. 2002
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| 14 | CD28, CTLA4, ICOS
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| Assembly and annotation of human chromosome 2q33 sequence containing the CD28, CTLA4, and ICOS gene cluster: analysis by computational, comparative, and microarray approaches.
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| Ling V, Wu PW, Finnerty HF, Agostino MJ, Graham JR, Chen S, Jussiff JM, Fisk GJ, Miller CP, Collins M.
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| Genomics 78(3):155-68. 2001
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| 15 | CD28
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| Transcriptional regulation of CD28 expression by CD28GR, a novel promoter element located in exon 1 of the CD28 gene.
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| Lin CJ, Tam RC.
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| J Immunol 166(10):6134-43. 2001
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| 16 | CBLB, CD28
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| Cbl-b regulates the CD28 dependence of T-cell activation.
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| Chiang YJ, Kole HK, Brown K, Naramura M, Fukuhara S, Hu RJ, Jang IK, Gutkind JS, Shevach E, Gu H.
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| Nature 403(6766):216-20 2000
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| 17 | ABI2, AOX1, BMPR2, CASP10, CASP8, CD28, CFLAR, CLK1, CTLA4, DAZAP2, MAGI2, ORC2, PPH1, PSMA2, SATB2, SUMO1, TRAK2
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| A physical and transcript map based upon refinement of the critical interval for PPH1, a gene for familial primary pulmonary hypertension.
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| Machado RD, Pauciulo MW, Fretwell N, Veal C, Thomson JR, Vilarino Guell C, Aldred M, Brannon CA, Trembath RC, Nichols WC.
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| Genomics 68(2):220-8. 2000
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| 18 | CD28, CTLA4
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| Common polymorphisms in the CTLA-4 and CD28 genes at 2q33 are not associated with asthma or atopy.
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| Heinzmann A, Plesnar C, Kuehr J, Forster J, Deichmann KA.
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| Eur J Immunogenet 27(2):57-61. 2000
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| 19 | CD28, CDIG3, CTLA4
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| The CTLA4/CD28 gene region on chromosome 2q33 confers susceptibility to celiac disease in a way possibly distinct from that of type 1 diabetes and other chronic inflammatory disorders.
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| Naluai AT, Nilsson S, Samuelsson L, Gudjonsdottir AH, Ascher H, Ek J, Hallberg B, Kristiansson B, Martinsson T, Nerman O, Sollid LM, Wahlstrom J.
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| Tissue Antigens 56(4):350-5. 2000
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| 20 | CD28, CDIG3, CTLA4
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| CD28/CTLA4 gene region on chromosome 2q33 confers genetic susceptibility to celiac disease. A linkage and family-based association study.
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| Holopainen P, et al.
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| Tissue Antigens 53(5):470-5. 1999
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| 21 | CD3@, CD28
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| CD3- and CD28-dependent induction of PDE7 required for T cell activation.
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| Li L, et al.
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| Science 283(5403):848-51. 1999
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| 22 | CD28
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| Identification of three alternatively spliced variants of human CD28 mRNA.
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| Magistrelli G, et al.
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| Biochem Biophys Res Commun 259(1):34-7. 1999
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| 23 | CD28, CTLA4
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| CTLA-4 ligation blocks CD28-dependent T cell activation.
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| Walunas TL, et al.
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| J Exp Med 183(6):2541-50. 1996
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| 24 | CTLA4, CD28
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| Molecular linkage of the human CTLA4 and CD28 Ig-superfamily genes in yeast artificial chromosomes.
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| Buonavista N, et al.
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| Genomics 13 : 856-861. 1992
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| 25 | CD28, CTLA4
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| CTLA-4 and CD2S activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location.
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| Harper K, et al.
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| J Immunol 147 : 1037-1044. 1991
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| 26 | CD28, CTLA4
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| Human CD28 and CTLA-4 Ig superfamily genes are located on chromosome 2 at bands q33-q34.
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| Lafage-Pochitaloff M, et al.
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| Immunogenetics 31 : 198-201. 1990
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| 27 | CD28
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| Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system.
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| Aruffo A, et al.
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| Proc Natl Acad Sci U S A 84 : 8573-8577. 1987
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