Citations for
B-cell homeostasis requires complementary CD22 and BLyS/BR3 survival signals.
Smith SH, Haas KM, Poe JC, Yanaba K, Ward CD, Migone TS, Tedder TF.
Int Immunol 22(8):681-91. Epub 2010 May 31.PMID: 20513733 2010
CD22 x Siglec-G double-deficient mice have massively increased B1 cell numbers and develop systemic autoimmunity.
Jellusova J, Wellmann U, Amann K, Winkler TH, Nitschke L.
J Immunol 184(7):3618-27. Epub 2010 Mar 3.PMID: 20200274 2010
Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo.
Duong BH, Tian H, Ota T, Completo G, Han S, Vela JL, Ota M, Kubitz M, Bovin N, Paulson JC, Nemazee D.
J Exp Med 207(1):173-87. Epub 2009 Dec 28. Erratum in: J Exp Med. 2010 Feb 15;207(2):445. Paulson, James [corrected to Paulson, James C]. 2010
CD22 EXON 12 deletion as a pathogenic mechanism of human B-precursor leukemia.
Uckun FM, Goodman P, Ma H, Dibirdik I, Qazi S.
Proc Natl Acad Sci U S A 107(39):16852-7. Epub 2010 Sep 14. 2010
5CD22, SH2D1A
SAP binds to CD22 and regulates B cell inhibitory signaling and calcium flux.
Ostrakhovitch EA, Wang Y, Li SS.
Cell Signal 21(4):540-50. Epub 2008 Dec 24. 2009
CD22 regulates time course of both B cell division and antibody response.
Onodera T, Poe JC, Tedder TF, Tsubata T.
J Immunol 180(2):907-13.PMID: 18178830 2008
Novel binding site for Src homology 2-containing protein-tyrosine phosphatase-1 in CD22 activated by B lymphocyte stimulation with antigen.
Zhu C, Sato M, Yanagisawa T, Fujimoto M, Adachi T, Tsubata T.
J Biol Chem 283(3):1653-9. Epub 2007 Nov 15. Erratum in: J Biol Chem. 2008 Feb 29;283(9):5972. Adachi, Takahiro [added]. PMID: 18024433 2008
Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity.
Tateno H, Li H, Schur MJ, Bovin N, Crocker PR, Wakarchuk WW, Paulson JC.
Mol Cell Biol 27(16):5699-710. Epub 2007 Jun 11. 2007
Decreased expression levels of CD22 and L-selectin on peripheral blood B lymphocytes from patients with bullous pemphigoid.
Inaoki M, Echigo T, Hayashi H, Nagaoka T, Hasegawa M, Takehara K, Fujimoto W, Tedder TF, Sato S.
J Autoimmun 27(3):196-202. Epub 2006 Oct 18. 2006
Diagnostic usefulness of aberrant CD22 expression in differentiating neoplastic cells of B-Cell chronic lymphoproliferative disorders from admixed benign B cells in four-color multiparameter flow cytometry.
Huang J, Fan G, Zhong Y, Gatter K, Braziel R, Gross G, Bakke A.
Am J Clin Pathol 123(6):826-32. 2005
CD22 attenuates calcium signaling by potentiating plasma membrane calcium-ATPase activity.
Chen J, McLean PA, Neel BG, Okunade G, Shull GE, Wortis HH.
Nat Immunol 5(6):651-7. Epub 2004 May 9. 2004
Identification of the gene variations in human CD22.
Hatta Y, et al.
Immunogenetics 49(4):280-6. 1999
13SIGLEC1, CD22, CD33, MAG
Sialoadhesin (Sn) maps to mouse chromosome 2 and human chromosome 20 and is not linked to the other members of the sialoadhesin family, CD22, MAG and CD33.
Mucklow S, et al.
Genomics 28 : 344-346. 1995
Genomic structure and chromosomal mapping of the human CD22 gene.
Wilson GL, et al.
J Immunol 150 : 5013-5024. 1993