| 1 | CCL11, CCR3
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| CCL11, a novel mediator of inflammatory bone resorption.
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| Kindstedt E, Holm CK, Sulniute R, Martinez-Carrasco I, Lundmark R, Lundberg P.
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| Sci Rep. Jul 13;7(1):5334. doi: 10.1038/s41598-017-05654-w 2017
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| 2 | CCL24, CCR3
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| Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart.
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| Diny NL, Hou X, Barin JG, Chen G, Talor MV, Schaub J, Russell SD, Klingel K, Rose NR, Čiháková D.
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| Eur J Immunol. Dec;46(12):2749-2760. doi: 10.1002/eji.201646557. Epub 2016 Oct 25 2016
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| 3 | CCR1, CCR3
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| A polymorphism in CCR1/CCR3 is associated with narcolepsy.
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| Toyoda H, Miyagawa T, Koike A, Kanbayashi T, Imanishi A, Sagawa Y, Kotorii N, Kotorii T, Hashizume Y, Ogi K, Hiejima H, Kamei Y, Hida A, Miyamoto M, Imai M, Fujimura Y, Tamura Y, Ikegami A, Wada Y, Moriya S, Furuya H, Takeuchi M, Kirino Y, Meguro A, Remmers EF, Kawamura Y, Otowa T, Miyashita A, Kashiwase K, Khor SS, Yamasaki M, Kuwano R, Sasaki T, Ishigooka J, Kuroda K, Kume K, Chiba S, Yamada N, Okawa M, Hirata K, Mizuki N, Uchimura N, Shimizu T, Inoue Y, Honda Y, Mishima K, Honda M, Tokunaga K.
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| Brain Behav Immun 49:148-55. doi: 10.1016/j.bbi.2015.05.003. Epub 2015 May 15.
2015
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| 4 | CCL24, CCR3
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| Chemokine CCL24 promotes the growth and invasiveness of trophoblasts through ERK1/2 and PI3K signaling pathways in human early pregnancy.
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| Li H, Meng YH, Shang WQ, Liu LB, Chen X, Yuan MM, Jin LP, Li MQ, Li DJ.
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| Reproduction Nov;150(5):417-27. doi: 10.1530/REP-15-0119. Epub 2015 Aug 27. 2015
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| 5 | CCL11, CCR3
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| Rapid transport of CCL11 across the blood-brain barrier: regional variation and importance of blood cells.
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| Erickson MA, Morofuji Y, Owen JB, Banks WA.
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| J Pharmacol Exp Ther. Jun;349(3):497-507. doi: 10.1124/jpet.114.213074. Epub 2014 Apr 4 2014
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| 6 | CCL11, CCR3
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| Blood expression levels of chemokine receptor CCR3 and chemokine CCL11 in age-related macular degeneration: a case-control study.
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| Falk MK, Singh A, Faber C, Nissen MH, Hviid T, Sřrensen TL.
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| BMC Ophthalmol. Feb 27;14:22. doi: 10.1186/1471-2415-14-22 2014
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| 7 | CCL11, CCL24, CCL26, CCR3
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| CCL26/eotaxin-3 is more effective to induce the migration of eosinophils of asthmatics than CCL11/eotaxin-1 and CCL24/eotaxin-2.
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| Provost V, Larose MC, Langlois A, Rola-Pleszczynski M, Flamand N, Laviolette M.
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| J Leukoc Biol. Aug;94(2):213-22. doi: 10.1189/jlb.0212074. Epub 2013 Mar 26 2013
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| 8 | CCR1, CCR3
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| Two-stage association study in Chinese Han identifies two independent associations in CCR1/CCR3 locus as candidate for Behçet's disease susceptibility.
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| Hou S, Xiao X, Li F, Jiang Z, Kijlstra A, Yang P.
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| Hum Genet 131(12):1841-50. doi: 10.1007/s00439-012-1200-4. Epub 2012 Jul 25.
2012
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| 9 | CCR3
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| Upregulation of CCR3 by age-related stresses promotes choroidal endothelial cell migration via VEGF-dependent and -independent signaling.
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| Wang H, Wittchen ES, Jiang Y, Ambati B, Grossniklaus HE, Hartnett ME.
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| Invest Ophthalmol Vis Sci. 52(11):8271-7. 2011
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| 10 | CCL26, CCR3, CX3CL1, CX3CR1, IL13, IL4
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| Eotaxin-3/CC chemokine ligand 26 is a functional ligand for CX3CR1.
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| Nakayama T, Watanabe Y, Oiso N, Higuchi T, Shigeta A, Mizuguchi N, Katou F, Hashimoto K, Kawada A, Yoshie O.
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| J Immunol. Dec 1;185(11):6472-9. doi: 10.4049/jimmunol.0904126. Epub 2010 Oct 25 2010
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| 11 | CCR3
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| CCR3 is a target for age-related macular degeneration diagnosis and therapy.
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| Takeda A, Baffi JZ, Kleinman ME, Cho WG, Nozaki M, Yamada K, Kaneko H, Albuquerque RJ, Dridi S, Saito K, Raisler BJ, Budd SJ, Geisen P, Munitz A, Ambati BK, Green MG, Ishibashi T, Wright JD, Humbles AA, Gerard CJ, Ogura Y, Pan Y, Smith JR, Grisanti S, Hartnett ME, Rothenberg ME, Ambati J.
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| Nature 460(7252):225-30. Epub 2009 Jun 14.
2009
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| 12 | CCR3, CENPB
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| Nuclear autoantigen CENP-B transactivation of the epidermal growth factor receptor via chemokine receptor 3 in vascular smooth muscle cells.
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| Robitaille G, Christin MS, Clément I, Senécal JL, Raymond Y.
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| Arthritis Rheum 60(9):2805-16. doi: 10.1002/art.24765.
2009
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| 13 | CCL26, CCR3
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| Post-transcriptional silencing of CCR3 downregulates IL-4 stimulated release of eotaxin-3 (CCL26) and other CCR3 ligands in alveolar type II cells.
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| Taka E, Errahali YJ, Abonyo BO, Bauer DM, Heiman AS.
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| Cytokine 44(3):342-51. Epub 2008 Nov 26.
2008
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| 14 | CCR3
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| Polymorphisms in chemokine receptor genes and susceptibility to Kawasaki disease.
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| Breunis WB, Biezeveld MH, Geissler J, Kuipers IM, Lam J, Ottenkamp J, Hutchinson A, Welch R, Chanock SJ, Kuijpers TW.
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| Clin Exp Immunol 150(1):83-90. Epub 2007 Aug 2.
2007
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| 15 | CCR1, CCR3
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| Dual role of CCL3/CCR1 in oral squamous cell carcinoma: implications in tumor metastasis and local host defense.
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| Silva TA, Ribeiro FL, Oliveira-Neto HH, Watanabe S, Alencar Rde C, Fukada SY, Cunha FQ, Leles CR, Mendonça EF, Batista AC.
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| Oncol Rep 18(5):1107-13.PMID: 17914560 2007
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| 16 | CCR3
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| A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation.
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| Fulkerson PC, Fischetti CA, McBride ML, Hassman LM, Hogan SP, Rothenberg ME.
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| Proc Natl Acad Sci U S A 103(44):16418-23. Epub 2006 Oct 23. 2006
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| 17 | CCL26, CCR3
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| Modulation of eotaxin-3 (CCL26) in alveolar type II epithelial cells.
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| Abonyo BO, Lebby KD, Tonry JH, Ahmad M, Heiman AS.
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| Cytokine 36(5-6):237-44. Epub 2007 Mar 9.
2006
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| 18 | CCR3
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| Transcription Regulation of Human Chemokine Receptor CCR3: Evidence for a Rare TATA-less Promoter Structure Conserved between Drosophila and Humans.
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| Vijh S, Dayhoff DE, Wang CE, Imam Z, Ehrenberg PK, Michael NL.
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| Genomics 80(1):86-95. 2002
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| 19 | CCL15, CCR1, CCR3
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| Leukotactin-1/CCL15-induced chemotaxis signaling through CCR1 in HOS cells.
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| Ko J, Kim IS, Jang SW, Lee YH, Shin SY, Min do S, Na DS.
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| FEBS Lett 515(1-3):159-64. 2002
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| 20 | CCR3
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| The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness.
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| Humbles AA, Lu B, Friend DS, Okinaga S, Lora J, Al-Garawi A, Martin TR, Gerard NP, Gerard C.
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| Proc Natl Acad Sci U S A. 99(3):1479-84. 2002
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| 21 | CCR3
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| CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation.
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| Ma W, Bryce PJ, Humbles AA, Laouini D, Yalcindag A, Alenius H, Friend DS, Oettgen HC, Gerard C, Geha RS.
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| J Clin Invest 109(5):621-8. 2002
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| 22 | CCR3
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| The ligands of CXC chemokine receptor 3, I-TAC, Mig, and IP10, are natural antagonists for CCR3.
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| Loetscher P, Pellegrino A, Gong JH, Mattioli I, Loetscher M, Bardi G, Baggiolini M, Clark-Lewis I.
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| J Biol Chem. 276(5):2986-91 2001
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| 23 | CCR3
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| Identification of potent, selective non-peptide CC chemokine receptor-3 antagonist that inhibits eotaxin-, eotaxin-2-, and monocyte chemotactic protein-4-induced eosinophil migration.
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| White JR, Lee JM, Dede K, Imburgia CS, Jurewicz AJ, Chan G, Fornwald JA, Dhanak D, Christmann LT, Darcy MG, Widdowson KL, Foley JJ, Schmidt DB, Sarau HM.
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| J Biol Chem 275(47):36626-31. 2000
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| 24 | CCR1, CCR3, CCR4, CXCR4
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| Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets.
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| Clemetson KJ, Clemetson JM, Proudfoot AE, Power CA, Baggiolini M, Wells TN.
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| Blood 96(13):4046-54. 2000
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| 25 | CCR3
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| Human thymocytes express CCR-3 and are activated by eotaxin.
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| Franz-Bacon K, et al.
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| Blood 93(10):3233-40. 1999
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| 26 | CCR1, CCR2, CCR3, CCR4, CCR5, CCR6, CCR7, CCR8, CCR9, CX3CR1, CXCR1, CXCR2, CXCR3, CXCR4, XCR1
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| Intracellular signalling pathways induced by chemokines in natural killer cells.
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| Maghazachi AA.
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| Cell Signal 11(6):385-90. Review 1999
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| 27 | C3CER1, CCR1, CCR2, CCR3, CCR4, CCR5, LTF
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| A 1-Mb PAC contig spanning the common eliminated region 1 (CER1) in microcell hybrid-derived SCID tumors.
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| Yang Y, Kiss H, Kost-Alimova M, Kedra D, Fransson I, Seroussi E, Li J, Szeles A, Kholodnyuk I, Imreh MP, Fodor K, Hadlaczky G, Klein G, Dumanski JP, Imreh S.
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| Genomics 62(2):147-55. 1999
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| 28 | CCR3
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| Novel association of the src family kinases, hck and c-fgr, with CCR3 receptor stimulation: A possible mechanism for eotaxin-induced human eosinophil chemotaxis.
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| El-Shazly A, Yamaguchi N, Masuyama K, Suda T, Ishikawa T.
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| Biochem Biophys Res Commun. 264(1):163-70. 1999
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| 29 | CCR3
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| Polymorphisms in the human CC chemokine receptor-3 gene.
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| Zimmermann N, Bernstein JA, Rothenberg ME.
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| Biochim Biophys Acta 1442 : 170-176. 1998
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| 30 | CCR1, CCR2, CCR3
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| The beta-chemokine receptor genes CCR1 (CMKBR1), CCR2 (CMKBR2), and CCR3 (CMKBR3) cluster within 285 kb on human chromosome 3p21.
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| Daugherty BL, et al.
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| Genomics 41 : 294-295. 1997
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| 31 | CCR3
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| Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells.
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| Sallusto F, Mackay CR, Lanzavecchia A.
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| Science 277(5334):2005-7. 1997
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| 32 | CCR1, CCR2, CCR3, CCR4, CCR5
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| The genes encoding the human CC-chemokine receptors CC-CKR1 to CC-CKR5 (CMKBR1-CMKBR5) are clustered in the p21.3-p24 region of chromosome 3.
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| Samson M, et al.
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| Genomics 36 : 522-526. 1996
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| 33 | CCR2, CCR3, CCR5
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| Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha.
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| Raport CJ, et al.
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| J Biol Chem 271 : 17161-17166. 1996
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| 34 | CCR3, CCL11
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| Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils.
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| Ponath PD, et al.
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| J Clin Invest 97 : 604-612. 1996
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| 35 | CCR3, CCL11
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| Molecular cloning of human eotaxin, an eosinophil-selective CC chemokine, and identification of a specific eosinophil eotaxin receptor, CC chemokine receptor 3.
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| Kitaura M, et al.
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| J Biol Chem 271 : 7725-7730. 1996
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| 36 | CCR3
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| Cloning and functional expression of a human eosinophil CC chemokine receptor.
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| Combadiere C, Ahuja SK, Murphy PM.
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| J Biol Chem 271(18):11034. No abstract available.
1996
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| 37 | CCR3
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| Cloning, expression, and characterization of the human eosinophil eotaxin receptor.
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| Daugherty BL, Siciliano SJ, DeMartino JA, Malkowitz L, Sirotina A, Springer MS.
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| J Exp Med. 183(5):2349-54. 1996
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