| 1 | CCNT1, HEXIM1
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| Hexim1, an RNA-controlled protein hub.
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| Michels AA, Bensaude O.
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| Transcription ranscription. 2018 Feb 23. doi: 10.1080/21541264.2018.1429836. [Epub ahead of print]
2018
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| 2 | CCNT1, MEPCE
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| Crosstalk between the RNA Methylation and Histone-Binding Activities of MePCE Regulates P-TEFb Activation on Chromatin.
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| Shelton SB, Shah NM, Abell NS, Devanathan SK, Mercado M, Xhemalçe B.
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| Cell Rep 22(6):1374-1383. doi: 10.1016/j.celrep.2018.01.028.
2018
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| 3 | CCNT1, CDK9, HEXIM1
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| An evolutionary conserved Hexim1 peptide binds to the Cdk9 catalytic site to inhibit P-TEFb.
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| Kobbi L, Demey-Thomas E, Braye F, Proux F, Kolesnikova O, Vinh J, Poterszman A, Bensaude O.
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| Proc Natl Acad Sci U S A roc Natl Acad Sci U S A. 2016 Oct 25. pii: 201612331. [Epub ahead of print]
2016
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| 4 | CCNT1, HEXIM1, LARP7, MEPCE, TAT
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| Solution structure of the 5'-terminal hairpin of the 7SK small nuclear RNA.
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| Bourbigot S, Dock-Bregeon AC, Eberling P, Coutant J, Kieffer B, Lebars I.
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| RNA 22(12):1844-1858. Epub 2016 Oct 20. 2016
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| 5 | CCNT1, PPM1G, RN7SK
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| PPM1G Binds 7SK RNA and Hexim1 To Block P-TEFb Assembly into the 7SK snRNP and Sustain Transcription Elongation.
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| Gudipaty SA, McNamara RP, Morton EL, D'Orso I.
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| Mol Cell Biol 35(22):3810-28. doi: 10.1128/MCB.00226-15. Epub 2015 Aug 31.
2015
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| 6 | CCNT1, LARP7
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| LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis.
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| Ji X, Lu H, Zhou Q, Luo K.
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| Elife 3:e02907. doi: 10.7554/eLife.02907.
2014
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| 7 | CCNT1, HEXIM1, LARP7, MEPCE
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| Release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein (snRNP) activates hexamethylene bisacetamide-inducible protein (HEXIM1) transcription.
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| Liu P, Xiang Y, Fujinaga K, Bartholomeeusen K, Nilson KA, Price DH, Peterlin BM.
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| J Biol Chem 289(14):9918-25. doi: 10.1074/jbc.M113.539015. Epub 2014 Feb 10.
2014
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| 8 | CCNT1
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| Inhibition of HIV-1 transcription and replication by a newly identified cyclin T1 splice variant.
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| Gao G, Wu X, Zhou J, He M, He JJ, Guo D.
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| J Biol Chem 288(20):14297-309. doi: 10.1074/jbc.M112.438465. Epub 2013 Apr 8.
2013
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| 9 | CCNT1, ELL, KMT2A
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| The super elongation complex (SEC) family in transcriptional control.
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| Luo Z, Lin C, Shilatifard A.
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| Nat Rev Mol Cell Biol 13(9):543-7. doi: 10.1038/nrm3417. Epub 2012 Aug 16. Review.
2012
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| 10 | CCNT1
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| Regulation of cyclin T1 expression and function by an alternative splice variant that skips exon 7 and contains a premature termination codon.
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| Urano E, Miyauchi K, Ichikawa R, Futahashi Y, Komano J.
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| Gene 505(1):1-8. doi: 10.1016/j.gene.2012.06.006. Epub 2012 Jun 9.
2012
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| 11 | CCNT1, HEXIM1
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| Functional characterization of a human cyclin T1 mutant reveals a different binding surface for Tat and HEXIM1.
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| Kuzmina A, Hadad U, Fujinaga K, Taube R.
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| Virology 426(2):152-61. doi: 10.1016/j.virol.2012.01.033. Epub 2012 Feb 18.
2012
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| 12 | CCNT1, HEXIM1
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| HEXIM1 controls satellite cell expansion after injury to regulate skeletal muscle regeneration.
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| Hong P, Chen K, Huang B, Liu M, Cui M, Rozenberg I, Chaqour B, Pan X, Barton ER, Jiang XC, Siddiqui MA.
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| J Clin Invest 122(11):3873-87.
2012
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| 13 | CCNT1, ELL, MED26
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| Human mediator subunit MED26 functions as a docking site for transcription elongation factors.
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| Takahashi H, Parmely TJ, Sato S, Tomomori-Sato C, Banks CA, Kong SE, Szutorisz H, Swanson SK, Martin-Brown S, Washburn MP, Florens L, Seidel CW, Lin C, Smith ER, Shilatifard A, Conaway RC, Conaway JW.
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| Cell 146(1):92-104. doi: 10.1016/j.cell.2011.06.005.
2011
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| 14 | CCNT1
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| Functional characterization of human cyclin T1 N-terminal region for human immunodeficiency virus-1 Tat transcriptional activation.
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| Asamitsu K, Hibi Y, Imai K, Victoriano AF, Kurimoto E, Kato K, Okamoto T.
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| J Mol Biol 410(5):887-95. doi: 10.1016/j.jmb.2011.04.061.
2011
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| 15 | CCNT1
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| Isolation and functional characterization of P-TEFb-associated factors that control general and HIV-1 transcriptional elongation.
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| Chen R, Liu M, Zhang K, Zhou Q.
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| Methods 53(1):85-90. doi: 10.1016/j.ymeth.2010.04.005. Epub 2010 Apr 10.
2011
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| 16 | CCNT1, HEXIM1
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| Structure and dynamics of a stabilized coiled-coil domain in the P-TEFb regulator Hexim1.
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| Bigalke JM, Dames SA, Blankenfeldt W, Grzesiek S, Geyer M.
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| J Mol Biol 414(5):639-53. doi: 10.1016/j.jmb.2011.10.022. Epub 2011 Oct 18.
2011
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| 17 | CCNT1, HEXIM1, RN7SK
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| The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SK.
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| Krueger BJ, Varzavand K, Cooper JJ, Price DH.
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| PLoS One 5(8):e12335. doi: 10.1371/journal.pone.0012335.
2010
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| 18 | CCNT1
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| Cyclin T1 overexpression induces malignant transformation and tumor growth.
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| Moiola C, De Luca P, Gardner K, Vazquez E, De Siervi A.
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| Cell Cycle 9(15):3119-26. doi: 10.4161/cc.9.15.12526.
2010
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| 19 | CCNT1, CDK9, HEXIM1, RNS7SK
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| T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes.
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| Dow EC, Liu H, Rice AP.
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| J Cell Physiol 224(1):84-93. doi: 10.1002/jcp.22096.
2010
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| 20 | CCNT1, HEXIM1, RN7SK
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| 7SK RNA, a non-coding RNA regulating P-TEFb, a general transcription factor.
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| Diribarne G, Bensaude O.
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| RNA Biol 6(2):122-8. Epub 2009 Apr 6. Review.PMID: 19246988 2009
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| 21 | LARP7, CCNT1
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| A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis.
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| He N, Jahchan NS, Hong E, Li Q, Bayfield MA, Maraia RJ, Luo K, Zhou Q.
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| Mol Cell 29(5):588-99. Epub 2008 Jan 31. 2008
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| 22 | LARP7, CCNT1
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| The La-related protein LARP7 is a component of the 7SK ribonucleoprotein and affects transcription of cellular and viral polymerase II genes.
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| Markert A, Grimm M, Martinez J, Wiesner J, Meyerhans A, Meyuhas O, Sickmann A, Fischer U.
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| EMBO Rep 9(6):569-75. Epub 2008 May 16. 2008
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| 23 | LARP7, CCNT1, HEXIM1
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| LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated.
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| Krueger BJ, Jeronimo C, Roy BB, Bouchard A, Barrandon C, Byers SA, Searcey CE, Cooper JJ, Bensaude O, Cohen EA, Coulombe B, Price DH.
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| Nucleic Acids Res 36(7):2219-29. Epub 2008 Feb 16. 2008
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| 24 | BRD4, CCNT1
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| Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression.
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| Yang Z, He N, Zhou Q.
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| Mol Cell Biol 28(3):967-76. Epub 2007 Nov 26.
2008
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| 25 | CCNT1, CDK9
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| Cdk9/Cyclin T1 complex: a key player during the activation/differentiation process of normal lymphoid B cells.
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| De Falco G, Leucci E, Onnis A, Bellan C, Tigli C, Wirths S, Cerino G, Cocco M, Crupi D, De Luca A, Lanzavecchia A, Tosi P, Leoncini L, Giordano A.
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| J Cell Physiol 215(1):276-82.PMID: 18205180 2008
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| 26 | CCNT1, HEXIM1, LARP7, MEPCE
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| LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated.
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| Krueger BJ, Jeronimo C, Roy BB, Bouchard A, Barrandon C, Byers SA, Searcey CE, Cooper JJ, Bensaude O, Cohen EA, Coulombe B, Price DH.
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| Nucleic Acids Res 36(7):2219-29. doi: 10.1093/nar/gkn061. Epub 2008 Feb 16.
2008
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| 27 | HEXIM1, CCNT1
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| Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb.
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| Dames SA, Schšnichen A, Schulte A, Barboric M, Peterlin BM, Grzesiek S, Geyer M.
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| Proc Natl Acad Sci U S A 104(36):14312-7. Epub 2007 Aug 27. 2007
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| 28 | MDFIC, CCNT1
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| The human I-mfa domain-containing protein, HIC, interacts with cyclin T1 and modulates P-TEFb-dependent transcription.
|
| Young TM, Wang Q, Pe'ery T, Mathews MB.
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| Mol Cell Biol 23(18):6373-84. 2003
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| 29 | CCNK, CCNT2, CDK9, CCNT1
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| P-TEFb containing cyclin K and Cdk9 can activate transcription via RNA.
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| Lin X, Taube R, Fujinaga K, Peterlin BM.
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| J Biol Chem 277(19):16873-8. 2002
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| 30 | CCNT1
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| in V3 loop region based on seroreactivity and amino acid sequences in Thailand.
|
| Balachandra K, Matsuo K, Sutthent R, Hoisanka N, Boonsarthorn N, Sawanpanyalert P, Warachit P, Yamazaki S, Honda M.
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| Asian Pac J Allergy Immunol 20(2):93-8. 2002
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| 31 | CCNT1
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| Isolation and characterization of the human cyclin T1 promoter.
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| Liu H, Rice AP.
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| Gene 252(1-2):39-49. 2000
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| 32 | CCNT1
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| A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA.
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| Wei P, et al.
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| Cell 92 : 451-462. 1998
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| 33 | CCNT1
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| Identification of multiple cyclin subunits of human P-TEFb.
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| Peng J, et al.
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| Genes Dev 12 : 755-762. 1998
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| 34 | CCNT1
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| Regional assignment of a gene(s) that encodes a cellular factor(s) for enhanced expression of primate lentiviruses in human/hamster hybrid cells.
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| Law ML, et al.
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| Am J Hum Genet 47 : A255. 1990
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| 35 | CCNT1
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| Human chromosome 12 encodes a species specific factor which increases human immunodeficiency virus type 1 tat-mediated trans activation in rodent cells.
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| Newstein M, et al.
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| J Virol 64 : 4565-4567. 1990
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| 36 | CCNT1
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| Human chromosome 12 is required for elevated HIV-1 expression in human-hamster hybrid cells.
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| Hart CE, et al.
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| Science 246 : 488-491. 1989
|