| 1 | CCNE1, USP27X
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| USP27-mediated Cyclin E stabilization drives cell cycle progression and hepatocellular tumorigenesis. .
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| Dong L, Yu L, Bai C, Liu L, Long H, Shi L, Lin Z.
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| Oncogene May;37(20):2702-2713. doi: 10.1038/s41388-018-0137-z. Epub 2018 Mar 2. 2018
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| 2 | CCND1, CCNE1, CDK2, CDK4, CIAPIN1
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| The study on expression of CIAPIN1 interfering hepatocellular carcinoma cell proliferation and its mechanisms.
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| Huang Z, Su GF, Hu WJ, Bi XX, Zhang L, Wan G.
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| Eur Rev Med Pharmacol Sci 21(13):3054-3060.
2017
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| 3 | CCNE1, ESR1, REL, TUBA1B
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| Identification of crucial genes related to postmenopausal osteoporosis using gene expression profiling
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| Ma M, Chen X, Lu L, Yuan F, Zeng W, Luo S, Yin F, Cai J.
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| Aging Clin Exp Res. Dec;28(6):1067-1074. doi: 10.1007/s40520-015-0509-y. Epub 2015 Dec 16. 2016
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| 4 | CCNE1, CDK2, HOXA7
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| HOXA7 stimulates human hepatocellular carcinoma proliferation through cyclin E1/CDK2.
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| Li Y, Yang XH, Fang SJ, Qin CF, Sun RL, Liu ZY, Jiang BY, Wu X, Li G.
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| Oncol Rep 33(2):990-6. doi: 10.3892/or.2014.3668. Epub 2014 Dec 11.
2015
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| 5 | BMI1, CCNE1, CDKN1A
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| p21/Cyclin E pathway modulates anticlastogenic function of Bmi-1 in cancer cells.
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| Deng W, Zhou Y, Tiwari AF, Su H, Yang J, Zhu D, Lau VM, Hau PM, Yip YL, Cheung AL, Guan XY, Tsao SW.
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| Int J Cancer 136(6):1361-70. doi: 10.1002/ijc.29114. Epub 2014 Aug 7.
2015
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| 6 | CCNE1, KCNB1
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| p21/Cyclin E pathway modulates anticlastogenic function of Bmi-1 in cancer cells.
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| Deng W, Zhou Y, Tiwari AF, Su H, Yang J, Zhu D, Lau VM, Hau PM, Yip YL, Cheung AL, Guan XY, Tsao SW.
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| Int J Cancer 136(6):1361-70. doi: 10.1002/ijc.29114. Epub 2014 Aug 7.
2015
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| 7 | CCNE1, LIN9, RBL1, RBL2
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| LIN-9 phosphorylation on threonine-96 is required for transcriptional activation of LIN-9 target genes and promotes cell cycle progression.
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| Eckerdt F, Perez-Neut M, Colamonici OR.
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| PLoS One 9(1):e87620. doi: 10.1371/journal.pone.0087620. eCollection 2014.
2014
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| 8 | CCNE1
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| Why are the truncated cyclin Es more effective CDK2 activators than the full-length isoforms?
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| Rath SL, Senapati S.
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| Biochemistry 53(28):4612-24. doi: 10.1021/bi5004052. Epub 2014 Jul 10.
2014
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| 9 | CCNE1, CCNE2
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| Mammalian E-type cyclins control chromosome pairing, telomere stability and CDK2 localization in male meiosis.
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| Martinerie L, Manterola M, Chung SS, Panigrahi SK, Weisbach M, Vasileva A, Geng Y, Sicinski P, Wolgemuth DJ.
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| PLoS Genet 10(2):e1004165. doi: 10.1371/journal.pgen.1004165. eCollection 2014 Feb. Erratum in: PLoS Genet. 2014 Apr;10(4):e1004350.
2014
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| 10 | CCNE1
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| Cyclin E1 (CCNE1) as independent positive prognostic factor in advanced stage serous ovarian cancer patients - a study of the OVCAD consortium.
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| Pils D, Bachmayr-Heyda A, Auer K, Svoboda M, Auner V, Hager G, Obermayr E, Reiner A, Reinthaller A, Speiser P, Braicu I, Sehouli J, Lambrechts S, Vergote I, Mahner S, Berger A, Cacsire Castillo-Tong D, Zeillinger R.
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| Eur J Cancer 50(1):99-110. doi: 10.1016/j.ejca.2013.09.011. Epub 2013 Oct 28.
2014
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| 11 | CCND1, CCNE1, CSF2
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| GM-CSF induces cyclin D1 expression and proliferation of endothelial progenitor cells via PI3K and MAPK signaling.
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| Qiu C, Xie Q, Zhang D, Chen Q, Hu J, Xu L.
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| Cell Physiol Biochem 33(3):784-95. doi: 10.1159/000358652. Epub 2014 Mar 7.
2014
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| 12 | CCNE1, RHOBTB3
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| Golgi-associated RhoBTB3 targets cyclin E for ubiquitylation and promotes cell cycle progression.
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| Lu A, Pfeffer SR.
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| J Cell Biol 203(2):233-50. doi: 10.1083/jcb.201305158. Epub 2013 Oct 21.
2013
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| 13 | CCNE1, RSF1
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| Rsf-1, a chromatin remodelling protein, interacts with cyclin E1 and promotes tumour development.
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| Sheu JJ, Choi JH, Guan B, Tsai FJ, Hua CH, Lai MT, Wang TL, Shih IeM.
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| J Pathol 229(4):559-68. doi: 10.1002/path.4147. Epub 2013 Feb 4.
2013
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| 14 | CCNE1, CCNE2
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| Cyclin E2 induces genomic instability by mechanisms distinct from cyclin E1.
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| Caldon CE, Sergio CM, Burgess A, Deans AJ, Sutherland RL, Musgrove EA.
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| Cell Cycle 12(4):606-17. doi: 10.4161/cc.23512. Epub 2013 Jan 16.
2013
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| 15 | CCND1, CCNE1, KDM5A
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| Histone demethylase RBP2 promotes lung tumorigenesis and cancer metastasis.
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| Teng YC, Lee CF, Li YS, Chen YR, Hsiao PW, Chan MY, Lin FM, Huang HD, Chen YT, Jeng YM, Hsu CH, Yan Q, Tsai MD, Juan LJ.
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| Cancer Res 73(15):4711-21. doi: 10.1158/0008-5472.CAN-12-3165. Epub 2013 May 30.
2013
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| 16 | CCNE1, MRPL21, NDUFA6, TEAD1
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| TEAD1 controls C2C12 cell proliferation and differentiation and regulates three novel target genes.
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| Wang F, Wang H, Wu H, Qiu H, Zeng C, Sun L, Liu B.
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| Cell Signal 25(3):674-81. doi: 10.1016/j.cellsig.2012.11.027. Epub 2012 Dec 3.
2013
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| 17 | BMI1, CCNE1, FBXW7
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| Cyclin E1 is a common target of BMI1 and MYCN and a prognostic marker for neuroblastoma progression.
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| Mao L, Ding J, Perdue A, Yang L, Zha Y, Ren M, Huang S, Cui H, Ding HF.
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| Oncogene 31(33):3785-95. doi: 10.1038/onc.2011.536. Epub 2011 Nov 28.
2012
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| 18 | CCNE1, FYB1, SKAP1
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| ADAP regulates cell cycle progression of T cells via control of cyclin E and Cdk2 expression through two distinct CARMA1-dependent signaling pathways.
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| Srivastava R, Burbach BJ, Mitchell JS, Pagán AJ, Shimizu Y.
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| Mol Cell Biol 32(10):1908-17. doi: 10.1128/MCB.06541-11. Epub 2012 Mar 12. 2012
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| 19 | CCNE1, CDKN1B, YWHAE
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| 14-3-3ε plays a role in cardiac ventricular compaction by regulating the cardiomyocyte cell cycle.
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| Kosaka Y, Cieslik KA, Li L, Lezin G, Maguire CT, Saijoh Y, Toyo-oka K, Gambello MJ, Vatta M, Wynshaw-Boris A, Baldini A, Yost HJ, Brunelli L.
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| Mol Cell Biol 32(24):5089-102. doi: 10.1128/MCB.00829-12. Epub 2012 Oct 15.
2012
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| 20 | CCNE1, CCNE2
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| Hypoxia-inducible factor 1 is activated by dysregulated cyclin E during mammary epithelial morphogenesis.
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| Sengupta T, Abraham G, Xu Y, Clurman BE, Minella AC.
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| Mol Cell Biol 31(18):3885-95. doi: 10.1128/MCB.05089-11. Epub 2011 Jul 11.
2011
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| 21 | CCNE1
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| Cyclin E1 is amplified and overexpressed in osteosarcoma.
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| Lockwood WW, Stack D, Morris T, Grehan D, O'Keane C, Stewart GL, Cumiskey J, Lam WL, Squire JA, Thomas DM, O'Sullivan MJ.
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| J Mol Diagn 13(3):289-96. doi: 10.1016/j.jmoldx.2010.11.020. Epub 2011 Mar 31.
2011
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| 22 | CCNE1, CCNE2
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| Expression of cyclin E in postmitotic neurons during development and in the adult mouse brain.
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| Ikeda Y, Matsunaga Y, Takiguchi M, Ikeda MA.
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| Gene Expr Patterns 11(1-2):64-71. doi: 10.1016/j.gep.2010.09.004. Epub 2010 Sep 21.
2011
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| 23 | CCNE1, CD79A, POU2AF1
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| BOB.1, CD79a and cyclin E are the most appropriate markers to discriminate classical Hodgkin's lymphoma from primary mediastinal large B-cell lymphoma.
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| Hoeller S, Zihler D, Zlobec I, Obermann EC, Pileri SA, Dirnhofer S, Tzankov A.
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| Histopathology 56(2):217-28.
2010
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| 24 | CCNE1, DDX3X
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| DDX3 regulates cell growth through translational control of cyclin E1.
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| Lai MC, Chang WC, Shieh SY, Tarn WY.
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| Mol Cell Biol 30(22):5444-53. doi: 10.1128/MCB.00560-10. Epub 2010 Sep 13.
2010
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| 25 | CCNE1, CCNE2
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| New roles for cyclin E in megakaryocytic polyploidization.
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| Eliades A, Papadantonakis N, Ravid K.
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| J Biol Chem 285(24):18909-17. doi: 10.1074/jbc.M110.102145. Epub 2010 Apr 14.
2010
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| 26 | CCNE1, CDK2, HINFP, NPAT
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| The histone gene activator HINFP is a nonredundant cyclin E/CDK2 effector during early embryonic cell cycles.
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| Xie R, Medina R, Zhang Y, Hussain S, Colby J, Ghule P, Sundararajan S, Keeler M, Liu LJ, van der Deen M, Mitra P, Lian JB, Rivera-Perez JA, Jones SN, Stein JL, van Wijnen AJ, Stein GS.
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| Proc Natl Acad Sci U S A 106(30):12359-64. Epub 2009 Jul 9.
2009
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| 27 | CCNE1
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| Post-translational modification and stability of low molecular weight cyclin E.
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| Mull BB, Cox J, Bui T, Keyomarsi K.
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| Oncogene 28(35):3167-76. Epub 2009 Jun 29.PMID: 19561641 2009
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| 28 | CCNE1
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| Prognostic relevance of cyclin E expression in operable breast cancer.
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| Potemski P, Kusińska R, Pasz-Walczak G, Piekarski JH, Watała C, Płuciennik E, Bednarek AK, Kordek R.
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| Med Sci Monit 15(2):MT34-40.PMID: 19179977 2009
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| 29 | CCNE1, CCNE2, E2F1
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| Role of E2F1-cyclin E1-cyclin E2 circuit in human coronary smooth muscle cell proliferation and therapeutic potential of its downregulation by siRNAs.
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| Dapas B, Farra R, Grassi M, Giansante C, Fiotti N, Uxa L, Rainaldi G, Mercatanti A, Colombatti A, Spessotto P, Lacovich V, Guarnieri G, Grassi G.
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| Mol Med 15(9-10):297-306. doi: 10.2119/molmed.2009.00030. Epub 2009 Jun 25.
2009
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| 30 | CCNE1, CCNE2
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| SCF(Fbxw7/hCdc4) targets cyclin E2 for ubiquitin-dependent proteolysis.
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| Klotz K, Cepeda D, Tan Y, Sun D, Sangfelt O, Spruck C.
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| Exp Cell Res 315(11):1832-9. doi: 10.1016/j.yexcr.2008.11.017. Epub 2008 Dec 3.
2009
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| 31 | CCNE1, MCM5
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| Cyclin E-dependent localization of MCM5 regulates centrosome duplication.
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| Ferguson RL, Maller JL.
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| J Cell Sci 121(Pt 19):3224-32.PMID: 18799789 2008
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| 32 | CCNE1
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| Kinase-independent function of cyclin E.
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| Geng Y, Lee YM, Welcker M, Swanger J, Zagozdzon A, Winer JD, Roberts JM, Kaldis P, Clurman BE, Sicinski P.
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| Mol Cell 25(1):127-39.PMID: 17218276 2007
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| 33 | CCNE1, XRCC6
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| Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis.
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| Mazumder S, Plesca D, Kinter M, Almasan A.
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| Mol Cell Biol 27(9):3511-20. Epub 2007 Feb 26.PMID: 17325036 2007
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| 34 | CCNE1, CCNE2
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| Kinase-independent function of cyclin E.
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| Geng Y, Lee YM, Welcker M, Swanger J, Zagozdzon A, Winer JD, Roberts JM, Kaldis P, Clurman BE, Sicinski P.
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| Mol Cell 25(1):127-39.
2007
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| 35 | CARM1, PRMT5, CCNE1
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| Coactivator-associated arginine methyltransferase 1 (CARM1) is a positive regulator of the Cyclin E1 gene.
|
| El Messaoudi S, Fabbrizio E, Rodriguez C, Chuchana P, Fauquier L, Cheng D, Theillet C, Vandel L, Bedford MT, Sardet C.
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| Proc Natl Acad Sci U S A 103(36):13351-6. Epub 2006 Aug 28. 2006
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| 36 | CCNE1
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| The prognostic value and overexpression of cyclin A is correlated with gene amplification of both cyclin A and cyclin E in breast cancer patient.
|
| Husdal A, Bukholm G, Bukholm IR.
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| Cell Oncol 28(3):107-16. 2006
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| 37 | CCNE1
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| Cyclin E expression in breast cancer correlates with negative steroid receptor status, HER2 expression, tumor grade and proliferation.
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| Potemski P, Kusinska R, Watala C, Pluciennik E, Bednarek AK, Kordek R.
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| J Exp Clin Cancer Res 25(1):59-64. 2006
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| 38 | FBXW7, CCNE1
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| Inactivation of hCDC4 can cause chromosomal instability.
|
| Rajagopalan H, Jallepalli PV, Rago C, Velculescu VE, Kinzler KW, Vogelstein B, Lengauer C.
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| Nature 428(6978):77-81. 2004
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| 39 | CCNE1
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| A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry.
|
| Matsumoto Y, Maller JL.
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| Science 306(5697):885-8. 2004
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| 40 | CCND1, CCNE1
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| Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.
|
| Duman-Scheel M, Weng L, Xin S, Du W.
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| Nature 417(6886):299-304. 2002
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| 41 | FBXW7, CCNE1
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| Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase.
|
| Koepp DM, Schaefer LK, Ye X, Keyomarsi K, Chu C, Harper JW, Elledge SJ.
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| Science 294(5540):173-7. 2001
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| 42 | CCNE1, CDK2, NPM1
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| Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication.
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| Okuda M, Horn HF, Tarapore P, Tokuyama Y, Smulian AG, Chan PK, Knudsen ES, Hofmann IA, Snyder JD, Bove KE, Fukasawa K.
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| Cell 103(1):127-40. 2000
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| 43 | CDK2, CCNE1
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| Deregulated cyclin E induces chromosome instability.
|
| Spruck CH, et al.
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| Nature 401(6750):297-300 1999
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| 44 | CCNE1, CCT2, CCT4, CCT7
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| Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT.
|
| Won KA, et al.
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| Mol Cell Biol 18(12):7584-9. 1998
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| 45 | CCNE1
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| Cyclin ET, a new splice variant of human cyclin E with a unique expression pattern during cell cycle progression and differentiation.
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| Mumberg D, Wick M, Burger C, Haas K, Funk M, Muller R.
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| Nucleic Acids Res 25(11):2098-105. 1997
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| 46 | CCNC, CCNE1
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| Molecular cloning and chromosomal localization of the human cyclin C (CCNC) and cyclin E (CCNE) genes : deletion of the CCNC gene in human tumors.
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| Li H, et al.
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| Genomics 32 : 253-259. 1996
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| 47 | CCNC, CCNE1, CDKN1A, CDKN3
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| Chromosomal mapping of the genes for the human cell cycle proteins cyclin C (CCNC), cyclin E (CCNE), p21 (CDKN1) and KAP (CDKN3).
|
| Demetrick DJ, et al.
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| Cytogenet Cell Genet 69 : 190-192. 1995
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| 48 | CCNE1
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| Alternative splicing of human cyclin E.
|
| Sewing A, Ronicke V, Burger C, Funk M, Muller R.
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| J Cell Sci 107 ( Pt 2):581-8. 1994
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| 49 | CCNE1
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| Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle.
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| Koff A, Giordano A, Desai D, Yamashita K, Harper JW, Elledge S, Nishimoto T, Morgan DO, Franza BR, Roberts JM.
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| Science 257(5077):1689-94.PMID: 1388288 1992
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| 50 | CCNE1
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| Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family.
|
| Koff A, et al.
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| Cell 66 : 1217-1228. 1991
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| 51 | CCNC, CCNE1
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| Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast.
|
| Lew DJ, et al.
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| Cell 66 : 1197-1206. 1991
|