| 1 | CCND2, GDDMP, MAX
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| A recurrent de novo MAX p.Arg60Gln variant causes a syndromic overgrowth disorder through differential expression of c-Myc target genes
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| Harris EL, Roy V, Montagne M, Rose AMS, Livesey H, Reijnders MRF, Hobson E, Sansbury FH, Willemsen MH, Pfundt R, Warren D, Long V, Carr IM, Brunner HG, Sheridan EG, Firth HV, Lavigne P, Poulter JA.
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| Am J Hum Genet. Jan 4;111(1):119-132. doi: 10.1016/j.ajhg.2023.11.010. Epub 2023 Dec 22 2024
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| 2 | CCND2, CDC25B, PTBP1, PTBP2, RBL1
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| Polypyrimidine tract-binding proteins are essential for B cell development.
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| Monzón-Casanova E, Matheson LS, Tabbada K, Zarnack K, Smith CW, Turner M.
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| Elife 9. pii: e53557. doi: 10.7554/eLife.53557.
2020
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| 3 | CCND2, NAV2
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| Neuron navigator-2 and cyclin D2 are new candidate prognostic markers in uterine sarcoma.
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| Davidson B, Hellesylt E, Holth A, Danielsen HE, Skeie-Jensen T, Katz B.
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| Virchows Arch 471(3):355-362. doi: 10.1007/s00428-017-2172-5. Epub 2017 Jun 22.
2017
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| 4 | CCND2, MPPH3
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| De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome.
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| Mirzaa GM, Parry DA, Fry AE, Giamanco KA, Schwartzentruber J, Vanstone M, Logan CV, Roberts N, Johnson CA, Singh S, Kholmanskikh SS, Adams C, Hodge RD, Hevner RF, Bonthron DT, Braun KP, Faivre L, Rivière JB, St-Onge J, Gripp KW, Mancini GM, Pang K, Sweeney E, van Esch H, Verbeek N, Wieczorek D, Steinraths M, Majewski J; FORGE Canada Consortium, Boycott KM, Pilz DT, Ross ME, Dobyns WB, Sheridan EG.
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| Nat Genet 46(5):510-5. doi: 10.1038/ng.2948. Epub 2014 Apr 6.
2014
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| 5 | CCND2
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| Cyclin D2 plays a regulatory role in HBV replication.
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| Song CL, Ren JH, Ran LK, Li YG, Li XS, Chen X, Li WY, Huang AL, Chen J.
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| Virology 462-463:149-57. doi: 10.1016/j.virol.2014.05.027. Epub 2014 Jul 1.
2014
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| 6 | CCND2, ETV4
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| Loss of a negative feedback loop involving pea3 and cyclin d2 is required for pea3-induced migration in transformed mammary epithelial cells.
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| Ladam F, Damour I, Dumont P, Kherrouche Z, de Launoit Y, Tulasne D, Chotteau-Lelievre A.
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| Mol Cancer Res 11(11):1412-24. doi: 10.1158/1541-7786.MCR-13-0229. Epub 2013 Aug 29.
2013
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| 7 | CCND2, SMO
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| Smoothened controls cyclin D2 expression and regulates the generation of intermediate progenitors in the developing cortex.
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| Komada M, Iguchi T, Takeda T, Ishibashi M, Sato M.
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| Neurosci Lett 547:87-91. doi: 10.1016/j.neulet.2013.05.006. Epub 2013 May 13.
2013
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| 8 | CCND2
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| Regulation of cyclin D2 expression and degradation by follicle-stimulating hormone during rat granulosa cell proliferation in vitro.
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| Han Y, Xia G, Tsang BK.
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| Biol Reprod 88(3):57. doi: 10.1095/biolreprod.112.105106. Print 2013 Mar.
2013
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| 9 | CCND2
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| Characterization of growth suppressive functions of a splice variant of cyclin D2.
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| Wafa K, MacLean J, Zhang F, Pasumarthi KB.
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| PLoS One 8(1):e53503. doi: 10.1371/journal.pone.0053503. Epub 2013 Jan 10.
2013
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| 10 | CCND2
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| The critical role of cyclin D2 in cell cycle progression and tumorigenicity of glioblastoma stem cells.
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| Koyama-Nasu R, Nasu-Nishimura Y, Todo T, Ino Y, Saito N, Aburatani H, Funato K, Echizen K, Sugano H, Haruta R, Matsui M, Takahashi R, Manabe E, Oda T, Akiyama T.
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| Oncogene 32(33):3840-5. doi: 10.1038/onc.2012.399. Epub 2012 Sep 10.
2013
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| 11 | CCND2, GATA4
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| Cyclin D2 rescues size and function of GATA4 haplo-insufficient hearts.
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| Yamak A, Temsah R, Maharsy W, Caron S, Paradis P, Aries A, Nemer M.
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| Am J Physiol Heart Circ Physiol 303(8):H1057-66. doi: 10.1152/ajpheart.00250.2012. Epub 2012 Aug 24.
2012
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| 12 | CCND2, GATA4
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| Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo.
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| Misra C, Sachan N, McNally CR, Koenig SN, Nichols HA, Guggilam A, Lucchesi PA, Pu WT, Srivastava D, Garg V.
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| PLoS Genet 8(5):e1002690. doi: 10.1371/journal.pgen.1002690. Epub 2012 May 10.
2012
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| 13 | CCND2
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| Cyclin D2 rescues size and function of GATA4 haplo-insufficient hearts.
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| Yamak A, Temsah R, Maharsy W, Caron S, Paradis P, Aries A, Nemer M.
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| Am J Physiol Heart Circ Physiol 303(8):H1057-66. doi: 10.1152/ajpheart.00250.2012. Epub 2012 Aug 24.
2012
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| 14 | CCND2
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| Age-dependent kinetics of dentate gyrus neurogenesis in the absence of cyclin D2.
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| Ansorg A, Witte OW, Urbach A.
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| BMC Neurosci 13:46. doi: 10.1186/1471-2202-13-46.
2012
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| 15 | CCND2
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| Cyclin D2 in the basal process of neural progenitors is linked to non-equivalent cell fates.
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| Tsunekawa Y, Britto JM, Takahashi M, Polleux F, Tan SS, Osumi N.
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| EMBO J 31(8):1879-92. doi: 10.1038/emboj.2012.43. Epub 2012 Mar 6.
2012
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| 16 | CCND2
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| Lack of cyclin D2 impairing adult brain neurogenesis alters hippocampal-dependent behavioral tasks without reducing learning ability.
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| Jedynak P, Jaholkowski P, Wozniak G, Sandi C, Kaczmarek L, Filipkowski RK.
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| Behav Brain Res 227(1):159-66. doi: 10.1016/j.bbr.2011.11.007. Epub 2011 Nov 15.
2012
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| 17 | CCND2, ZKSCAN3
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| Evidence of a role for the novel zinc-finger transcription factor ZKSCAN3 in modulating Cyclin D2 expression in multiple myeloma.
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| Yang L, Wang H, Kornblau SM, Graber DA, Zhang N, Matthews JA, Wang M, Weber DM, Thomas SK, Shah JJ, Zhang L, Lu G, Zhao M, Muddasani R, Yoo SY, Baggerly KA, Orlowski RZ.
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| Oncogene 30(11):1329-40. Epub 2010 Nov 8.
2011
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| 18 | CCND2
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| Developmental expression of the cyclin D2 splice variant in postnatal Purkinje cells of the mouse cerebellum.
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| Kajitani K, Wafa K, Pasumarthi KB, Robertson GS.
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| Neurosci Lett 477(2):100-4. doi: 10.1016/j.neulet.2010.04.042. Epub 2010 Apr 28.
2010
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| 19 | CCND2
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| Cyclin D2 is critical for intermediate progenitor cell proliferation in the embryonic cortex.
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| Glickstein SB, Monaghan JA, Koeller HB, Jones TK, Ross ME.
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| J Neurosci 29(30):9614-24. doi: 10.1523/JNEUROSCI.2284-09.2009.
2009
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| 20 | CCND2
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| Cyclin D2 is critical for intermediate progenitor cell proliferation in the embryonic cortex.
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| Glickstein SB, Monaghan JA, Koeller HB, Jones TK, Ross ME.
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| J Neurosci 29(30):9614-24. doi: 10.1523/JNEUROSCI.2284-09.2009.
2009
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| 21 | CCND2
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| Cyclin D2 protein stability is regulated in pancreatic beta-cells.
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| He LM, Sartori DJ, Teta M, Opare-Addo LM, Rankin MM, Long SY, Diehl JA, Kushner JA.
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| Mol Endocrinol 23(11):1865-75. doi: 10.1210/me.2009-0057. Epub 2009 Jul 23.
2009
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| 22 | CCND2
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| A splice variant of cyclin D2 regulates cardiomyocyte cell cycle through a novel protein aggregation pathway.
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| Sun Q, Zhang F, Wafa K, Baptist T, Pasumarthi KB.
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| J Cell Sci 122(Pt 10):1563-73. doi: 10.1242/jcs.047738. Epub 2009 Apr 28.
2009
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| 23 | CCND2
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| A polypyrimidine tract-binding protein-dependent pathway of mRNA stability initiates with CpG activation of primary B cells.
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| Porter JF, Vavassori S, Covey LR.
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| J Immunol 181(5):3336-45.
2008
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| 24 | CCND1, CCND2, CCND3
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| Crucial roles of D-type cyclins in the early stage of adipocyte differentiation.
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| Hishida T, Naito K, Osada S, Nishizuka M, Imagawa M.
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| Biochem Biophys Res Commun 370(2):289-94. Epub 2008 Mar 27.
2008
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| 25 | CCND2
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| Cyclin D2 translocates p27 out of the nucleus and promotes its degradation at the G0-G1 transition.
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| Susaki E, Nakayama K, Nakayama KI.
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| Mol Cell Biol 27(13):4626-40. Epub 2007 Apr 23.
2007
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| 26 | CCND2
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| Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer.
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| Henrique R, Costa VL, Cerveira N, Carvalho AL, Hoque MO, Ribeiro FR, Oliveira J, Teixeira MR, Sidransky D, Jerónimo C.
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| J Mol Med 84(11):911-8. Epub 2006 Sep 22.
2006
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| 27 | CCND1, CCND2, CCND3
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| Amplification and expression of cyclin D genes (CCND1, CCND2 and CCND3) in human malignant gliomas.
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| Buschges R, et al.
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| Brain Pathol 9(3):435-42; discussion 432-3 1999
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| 28 | CCND2
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| Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis.
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| Sicinski P, et al.
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| Nature 384 : 470-474. 1996
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| 29 | CCND2
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| The Vin-1 gene, identified by provirus insertional mutagenesis, is the cyclin D2.
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| Hanna Z, et al.
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| Oncogene 8 : 1661-1666. 1993
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| 30 | CCND2, CCND3
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| Molecular cloning and chromosomal mapping of CCND genes encoding human D-type cyclins.
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| Xiong Y, et al.
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| Genomics 13 : 575-584. 1992
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| 31 | CCND1, CCND2, CCND3, CCND2P, CCND3P
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| Genomic organization, chromosomal localization, and independent expression of human cyclin D genes.
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| Inaba T, et al.
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| Genomics 13 : 565-574. 1992
|