Citations for
1CCL4
CCL4 Signaling in the Tumor Microenvironment.
Mukaida N, Sasaki SI, Baba T.
Adv Exp Med Biol 1231:23-32. doi: 10.1007/978-3-030-36667-4_3. Review. 2020
2CCL4
The Cooperative Induction of CCL4 in Human Monocytic Cells by TNF-α and Palmitate Requires MyD88 and Involves MAPK/NF-κB Signaling Pathways.
Sindhu S, Kochumon S, Shenouda S, Wilson A, Al-Mulla F, Ahmad R.
Int J Mol Sci 20(18). pii: E4658. doi: 10.3390/ijms20184658. 2019
3CCL4, TNF
TNF-α Drives the CCL4 Expression in Human Monocytic Cells: Involvement of the SAPK/JNK and NF-κB Signaling Pathways.
Ahmad R, Kochumon S, Chandy B, Shenouda S, Koshy M, Hasan A, Arefanian H, Al-Mulla F, Sindhu S.
Cell Physiol Biochem 52(4):908-921. doi: 10.33594/000000063. 2019
4CCL4
Correlation between CCL4 gene polymorphisms and clinical aspects of breast cancer.
Hu GN, Tzeng HE, Chen PC, Wang CQ, Zhao YM, Wang Y, Su CM, Tang CH.
Int J Med Sci 15(11):1179-1186. doi: 10.7150/ijms.26771. eCollection 2018. 2018
5CCL3, CCL4
Decreased macrophage inflammatory protein (MIP)-1α and MIP-1β increase the risk of developing nasopharyngeal carcinoma.
Yang MJ, Guo J, Ye YF, Chen SH, Peng LX, Lin CY, Hu T, Xie SH, Xie CB, Huang QH, Lu YQ, Liu Q, Qian CN, Cao SM.
Cancer Commun (Lond) 38(1):7. doi: 10.1186/s40880-018-0279-y. 2018
6CCL4
Macrophage-derived foam cells impair endothelial barrier function by inducing endothelial-mesenchymal transition via CCL-4.
Yang Y, Luo NS, Ying R, Xie Y, Chen JY, Wang XQ, Gu ZJ, Mai JT, Liu WH, Wu MX, Chen ZT, Fang YB, Zhang HF, Zuo ZY, Wang JF, Chen YX.
Int J Mol Med 40(2):558-568. doi: 10.3892/ijmm.2017.3034. Epub 2017 Jun 19. 2017
7CCL4
Impact of CCL4 gene polymorphisms and environmental factors on oral cancer development and clinical characteristics.
Lien MY, Lin CW, Tsai HC, Chen YT, Tsai MH, Hua CH, Yang SF, Tang CH.
Oncotarget 8(19):31424-31434. doi: 10.18632/oncotarget.15615. 2017
8CCL3, CCL4
T regulatory cell chemokine production mediates pathogenic T cell attraction and suppression.
Patterson SJ, Pesenacker AM, Wang AY, Gillies J, Mojibian M, Morishita K, Tan R, Kieffer TJ, Verchere CB, Panagiotopoulos C, Levings MK.
J Clin Invest 126(3):1039-51. doi: 10.1172/JCI83987. Epub 2016 Feb 8. 2016
9CCL4, IL12B, IL1A, IL1B, STX3
An essential role of syntaxin 3 protein for granule exocytosis and secretion of IL-1α, IL-1β, IL-12b, and CCL4 from differentiated HL-60 cells.
Naegelen I, Plançon S, Nicot N, Kaoma T, Muller A, Vallar L, Tschirhart EJ, Bréchard S.
J Leukoc Biol 97(3):557-71. doi: 10.1189/jlb.3A0514-254RR. Epub 2014 Dec 29. 2015
10CCL4
Increased expression of CCL4/MIP-1β in CD8+ cells and CD4+ cells in sarcoidosis.
Barczyk A, Pierzchała E, Caramori G, Sozańska E.
Int J Immunopathol Pharmacol 27(2):185-93. 2014
11AR, CCL4, STAT3
Infiltrating macrophages promote prostate tumorigenesis via modulating androgen receptor-mediated CCL4-STAT3 signaling.
Fang LY, Izumi K, Lai KP, Liang L, Li L, Miyamoto H, Lin WJ, Chang C.
Cancer Res 73(18):5633-46. doi: 10.1158/0008-5472.CAN-12-3228. Epub 2013 Jul 22. 2013
12CCL4, CCR5
CC-chemokine ligand 4/macrophage inflammatory protein-1β participates in the induction of neuropathic pain after peripheral nerve injury.
Saika F, Kiguchi N, Kobayashi Y, Fukazawa Y, Kishioka S.
Eur J Pain 16(9):1271-80. doi: 10.1002/j.1532-2149.2012.00146.x. Epub 2012 Apr 24. 2012
13CCL2, CCL3, CCL4, CCL5
Adiponectin stimulates release of CCL2, -3, -4 and -5 while the surface abundance of CCR2 and -5 is simultaneously reduced in primary human monocytes.
Neumeier M, Bauer S, Brühl H, Eisinger K, Kopp A, Abke S, Walter R, Schäffler A, Buechler C.
Cytokine 56(3):573-80. doi: 10.1016/j.cyto.2011.08.017. Epub 2011 Sep 3. Erratum in: Cytokine. 2013 Jun;62(3):453. 2011
14CCL3, CCL4
Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme.
Ren M, Guo Q, Guo L, Lenz M, Qian F, Koenen RR, Xu H, Schilling AB, Weber C, Ye RD, Dinner AR, Tang WJ.
EMBO J 29(23):3952-66. doi: 10.1038/emboj.2010.256. Epub 2010 Oct 19. 2010
15CCL4
CCL4/MIP-1beta levels in tear fluid and serum of patients with cystic fibrosis.
Mrugacz M.
J Interferon Cytokine Res 30(7):509-12. doi: 10.1089/jir.2009.0102. 2010
16CCL4, CCR5
An arrestin-dependent multi-kinase signaling complex mediates MIP-1beta/CCL4 signaling and chemotaxis of primary human macrophages.
Cheung R, Malik M, Ravyn V, Tomkowicz B, Ptasznik A, Collman RG.
J Leukoc Biol 86(4):833-45. Epub 2009 Jul 20.PMID: 19620252 2009
17CCL4, CXCL1, IL8, PROK1
Prokineticin 1 induces CCL4, CXCL1 and CXCL8 in human monocytes but not in macrophages and dendritic cells.
Monnier J, Quillien V, Piquet-Pellorce C, Leberre C, Preisser L, Gascan H, Samson M.
Eur Cytokine Netw 19(4):166-75.PMID: 19103522 2008
18CCL3, CCL4
Possible role of the innate immunity in temporal lobe epilepsy.
van Gassen KL, de Wit M, Koerkamp MJ, Rensen MG, van Rijen PC, Holstege FC, Lindhout D, de Graan PN.
Epilepsia 49(6):1055-65. Epub 2007 Dec 11.PMID: 18076643 2008
19CCL3, CCL4, CCL18
Genetic Variation in the CCL18-CCL3-CCL4 Chemokine Gene Cluster Influences HIV Type 1 Transmission and AIDS Disease Progression.
Modi WS, Lautenberger J, An P, Scott K, Goedert JJ, Kirk GD, Buchbinder S, Phair J, Donfield S, O'brien SJ, Winkler C.
Am J Hum Genet 79(1):120-8. Epub 2006 May 30. 2006
20CCL14, CCL4, CX3CL1
The chemokines, CX3CL1, CCL14, and CCL4, promote human trophoblast migration at the feto-maternal interface.
Hannan NJ, Jones RL, White CA, Salamonsen LA.
Biol Reprod 74(5):896-904. Epub 2006 Feb 1. 2006
21CCL3L1, CCL3L2, CCL4, CCL4L1, CCL4L2
Multiple products derived from two CCL4 loci: high incidence of a new polymorphism in HIV+ patients.
Colobran R, Adreani P, Ashhab Y, Llano A, Este JA, Dominguez O, Pujol-Borrell R, Juan M.
J Immunol 174(9):5655-64. 2005
22CCL3L1, CCL3, CCL4, CCL4L1
CCL3L1 and CCL4L1 chemokine genes are located in a segmental duplication at chromosome 17q12.
Modi WS.
Genomics 83(4):735-8. 2004
23CCL4
Identification of human macrophage inflammatory proteins 1alpha and 1beta as a native secreted heterodimer.
Guan E, Wang J, Norcross MA.
J Biol Chem 276(15):12404-9. 2001
24CCL4, CCL4L1
The human MIP-1beta chemokine is encoded by two paralogous genes, ACT-2 and LAG-1
Modi WS, Bergeron J, Sanford M.
Immunogenetics 53(7):543-9. 2001
25CCL17, CCL4
The assignment of chemokine-chemokine receptor pairs: TARC and MIP-1 beta are not ligands for human CC-chemokine receptor 8.
Garlisi CG, Xiao H, Tian F, Hedrick JA, Billah MM, Egan RW, Umland SP.
Eur J Immunol 29(10):3210-5 1999
26CCL3, CCL4, CCL4L1, CCL5, CCL7, CCL11, CCL13, CCL20, CXCL12
Chemokines--chemotactic cytokines that mediate inflammation.
Luster AD.
N Engl J Med 338(7):436-45. Review. No abstract available. 1998
27CCL3, CCL4, CCL4L1, CCL3L1, CXCL2
Two inflammatory mediator cytokine genes are closely linked and variably amplified on chromosome 17q.
Irving SG, et al.
Nucleic Acids Res 18 : 3261-3270. 1990
28CCL4
Cloning and expression of a lymphocyte activation gene (LAG-1).
Baixeras E, Roman-Roman S, Jitsukawa S, Genevee C, Mechiche S, Viegas-Pequignot E, Hercend T, Triebel F.
Mol Immunol 27(11):1091-102.PMID: 2247088 1990