| 1 | CCL21, GPR174
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| GPR174-CCL21 module imparts sexual dimorphism to humoral immunity
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| Zhao R, Chen X, Ma W, Zhang J, Guo J, Zhong X, Yao J, Sun J, Rubinfien J, Zhou X, Wang J, Qi H. A
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| Nature Jan;577(7790):416-420. doi: 10.1038/s41586-019-1873-0. Epub 2019 Dec 25. 2020
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| 2 | CCL21, CCR7
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| Solution structure of CCL21 and identification of a putative CCR7 binding site.
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| Love M, Sandberg JL, Ziarek JJ, Gerarden KP, Rode RR, Jensen DR, McCaslin DR, Peterson FC, Veldkamp CT.
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| Biochemistry 51(3):733-5. doi: 10.1021/bi201601k. Epub 2012 Jan 17.
2012
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| 3 | CCL21, CCR7
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| CCL21/CCR7 promotes G2/M phase progression via the ERK pathway in human non-small cell lung cancer cells.
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| Xu Y, Liu L, Qiu X, Jiang L, Huang B, Li H, Li Z, Luo W, Wang E.
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| PLoS One 6(6):e21119. Epub 2011 Jun 16.
2011
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| 4 | CCL21, P2RX4
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| Neuronal CCL21 up-regulates microglia P2X4 expression and initiates neuropathic pain development.
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| Biber K, Tsuda M, Tozaki-Saitoh H, Tsukamoto K, Toyomitsu E, Masuda T, Boddeke H, Inoue K.
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| EMBO J 30(9):1864-73. Epub 2011 Mar 25.
2011
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| 5 | CCL19, CCL21
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| Combinatorial guidance by CCR7 ligands for T lymphocytes migration in co-existing chemokine fields.
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| Nandagopal S, Wu D, Lin F.
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| PLoS One 6(3):e18183.
2011
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| 6 | CCL21, CCR7
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| CCR7/CCL21 migration on fibronectin is mediated by phospholipase Cgamma1 and ERK1/2 in primary T lymphocytes.
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| Shannon LA, Calloway PA, Welch TP, Vines CM.
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| J Biol Chem 285(50):38781-7. Epub 2010 Oct 1.
2010
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| 7 | CCL21
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| Inflammation-induced secretion of CCL21 in lymphatic endothelium is a key regulator of integrin-mediated dendritic cell transmigration.
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| Johnson LA, Jackson DG.
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| Int Immunol 22(10):839-49. Epub 2010 Aug 25.
2010
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| 8 | CCL19, CCL21
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| Analysis of migratory and prosurvival pathways induced by the homeostatic chemokines CCL19 and CCL21 in B-cell chronic lymphocytic leukemia.
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| Cuesta-Mateos C, López-Giral S, Alfonso-Pérez M, de Soria VG, Loscertales J, Guasch-Vidal S, Beltrán AE, Zapata JM, Muñoz-Calleja C.
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| Exp Hematol 38(9):756-64, 764.e1-4. Epub 2010 May 19.
2010
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| 9 | CCL21
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| Association of a rheumatoid arthritis susceptibility variant at the CCL21 locus with premature mortality in inflammatory polyarthritis patients.
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| Farragher TM, Plant D, Flynn E, Eyre S, Bunn D, Thomson W, Symmons D, Barton A.
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| Arthritis Care Res (Hoboken) 62(5):676-82.
2010
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| 10 | CCL21
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| CCL21 overexpressed on lymphatic vessels drives thymic hyperplasia in myasthenia.
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| Berrih-Aknin S, Ruhlmann N, Bismuth J, Cizeron-Clairac G, Zelman E, Shachar I, Dartevelle P, de Rosbo NK, Le Panse R.
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| Ann Neurol 66(4):521-31.
2009
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| 11 | CCL21, CCR7
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| Interaction of polysialic acid with CCL21 regulates the migratory capacity of human dendritic cells.
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| Bax M, van Vliet SJ, Litjens M, García-Vallejo JJ, van Kooyk Y.
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| PLoS One 4(9):e6987.
2009
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| 12 | CCL21
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| Decreased expression of the chemokine CCL21 in human colorectal adenocarcinomas.
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| Mumtaz M, Wågsäter D, Löfgren S, Hugander A, Zar N, Dimberg J.
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| Oncol Rep 21(1):153-8.
2009
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| 13 | CCL21, CXCL13
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| Regulation of homeostatic chemokine expression and cell trafficking during immune responses.
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| Mueller SN, Hosiawa-Meagher KA, Konieczny BT, Sullivan BM, Bachmann MF, Locksley RM, Ahmed R, Matloubian M.
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| Science 317(5838):670-4. 2007
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| 14 | CCl19, CCL21
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| The N-terminal domain of CCL21 reconstitutes high affinity binding, G protein activation, and chemotactic activity, to the C-terminal domain of CCL19.
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| Ott TR, Lio FM, Olshefski D, Liu XJ, Ling N, Struthers RS.
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| Biochem Biophys Res Commun 348(3):1089-93. Epub 2006 Aug 4. 2006
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| 15 | CCL19, CCL21, CCR7
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| Expression of CCR7 and its ligands CCL19/CCL21 in muscles of polymyositis.
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| Tateyama M, Fujihara K, Misu T, Feng J, Onodera Y, Itoyama Y.
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| J Neurol Sci 249(2):158-65. Epub 2006 Aug 2. 2006
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| 16 | CCL21
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| The chemokine CCL21 modulates lymphocyte recruitment and fibrosis in chronic hepatitis C.
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| Bonacchi A, Petrai I, Defranco RM, Lazzeri E, Annunziato F, Efsen E, Cosmi L, Romagnani P, Milani S, Failli P, Batignani G, Liotta F, Laffi G, Pinzani M, Gentilini P, Marra F.
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| Gastroenterology 125(4):1060-76. 2003
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| 17 | CCL21
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| A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes.
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| Gunn MD, Tangemann K, Tam C, Cyster JG, Rosen SD, Williams LT.
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| Proc Natl Acad Sci U S A 95(1):258-63. 1998
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| 18 | CCL20, CCL21
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| Molecular cloning of a novel human CC chemokine secondary lymphoid-tissue chemokine that is a potent chemoattractant for lymphocytes and mapped to chromosome 9p13.
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| Nagira M, Imai T, Hieshima K, Kusuda J, Ridanpaa M, Takagi S, Nishimura M, Kakizaki M, Nomiyama H, Yoshie O.
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| J Biol Chem 272(31):19518-24. 1997
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