| 1 | CCDC88A
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| Girdin is an intrinsic regulator of neuroblast chain migration in the rostral migratory stream of the postnatal brain.
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| Wang Y, Kaneko N, Asai N, Enomoto A, Isotani-Sakakibara M, Kato T, Asai M, Murakumo Y, Ota H, Hikita T, Namba T, Kuroda K, Kaibuchi K, Ming GL, Song H, Sawamoto K, Takahashi M.
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| J Neurosci 31(22):8109-22.
2011
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| 2 | CCDC88A
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| Tyrosine phosphorylation of the Gα-interacting protein GIV promotes activation of phosphoinositide 3-kinase during cell migration.
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| Lin C, Ear J, Pavlova Y, Mittal Y, Kufareva I, Ghassemian M, Abagyan R, Garcia-Marcos M, Ghosh P.
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| Sci Signal 4(192):ra64.
2011
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| 3 | CCDC88A
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| The actin-binding protein Girdin and its Akt-mediated phosphorylation regulate neointima formation after vascular injury.
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| Miyake H, Maeda K, Asai N, Shibata R, Ichimiya H, Isotani-Sakakibara M, Yamamura Y, Kato K, Enomoto A, Takahashi M, Murohara T.
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| Circ Res 108(10):1170-9. Epub 2011 Mar 17.
2011
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| 4 | CCDC88A
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| Expression of GIV/Girdin, a metastasis-related protein, predicts patient survival in colon cancer.
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| Garcia-Marcos M, Jung BH, Ear J, Cabrera B, Carethers JM, Ghosh P.
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| FASEB J 25(2):590-9. Epub 2010 Oct 25.
2011
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| 5 | CCDC88A, NUCB1, NUCB2
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| G Protein binding sites on Calnuc (nucleobindin 1) and NUCB2 (nucleobindin 2) define a new class of G(alpha)i-regulatory motifs.
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| Garcia-Marcos M, Kietrsunthorn PS, Wang H, Ghosh P, Farquhar MG.
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| J Biol Chem 286(32):28138-49. Epub 2011 Jun 8.
2011
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| 6 | CCDC88A
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| A structural determinant that renders G alpha(i) sensitive to activation by GIV/girdin is required to promote cell migration.
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| Garcia-Marcos M, Ghosh P, Ear J, Farquhar MG.
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| J Biol Chem 285(17):12765-77. Epub 2010 Feb 15.
2010
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| 7 | CCDC88A
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| GIV is a nonreceptor GEF for G alpha i with a unique motif that regulates Akt signaling.
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| Garcia-Marcos M, Ghosh P, Farquhar MG.
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| Proc Natl Acad Sci U S A 106(9):3178-83. Epub 2009 Feb 11.
2009
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| 8 | CCDC88A
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| An actin-binding protein Girdin regulates the motility of breast cancer cells.
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| Jiang P, Enomoto A, Jijiwa M, Kato T, Hasegawa T, Ishida M, Sato T, Asai N, Murakumo Y, Takahashi M.
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| Cancer Res 68(5):1310-8.
2008
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| 9 | CCDC88A
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| Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin.
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| Kitamura T, Asai N, Enomoto A, Maeda K, Kato T, Ishida M, Jiang P, Watanabe T, Usukura J, Kondo T, Costantini F, Murohara T, Takahashi M.
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| Nat Cell Biol 10(3):329-37. Epub 2008 Feb 10.
2008
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| 10 | CCDC88A, GNAI3
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| Activation of Galphai3 triggers cell migration via regulation of GIV.
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| Ghosh P, Garcia-Marcos M, Bornheimer SJ, Farquhar MG.
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| J Cell Biol 182(2):381-93.
2008
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| 11 | CCDC88A
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| Akt/PKB regulates actin organization and cell motility via Girdin/APE.
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| Enomoto A, Murakami H, Asai N, Morone N, Watanabe T, Kawai K, Murakumo Y, Usukura J, Kaibuchi K, Takahashi M.
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| Dev Cell 9(3):389-402. 2005
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| 12 | CCDC88A, CCDC88B
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| A novel hook-related protein family and the characterization of hook-related protein 1.
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| Simpson F, Martin S, Evans TM, Kerr M, James DE, Parton RG, Teasdale RD, Wicking C.
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| Traffic 6(6):442-58. 2005
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| 13 | CCDC88A
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| Identification and characterization of GIV, a novel Galpha i/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles.
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| Le-Niculescu H, Niesman I, Fischer T, DeVries L, Farquhar MG.
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| J Biol Chem 280(23):22012-20. Epub 2005 Mar 4.
2005
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