Citations for
1CBLC, PDLIM7, RET
Enigma prevents Cbl-c-mediated ubiquitination and degradation of RETMEN2A.
Kales SC, Nau MM, Merchant AS, Lipkowitz S.
PLoS One 9(1):e87116. doi: 10.1371/journal.pone.0087116. eCollection 2014. 2014
2CBLC, TGFB1I1
Cbl-c ubiquitin ligase activity is increased via the interaction of its RING finger domain with a LIM domain of the paxillin homolog, Hic 5.
Ryan PE, Kales SC, Yadavalli R, Nau MM, Zhang H, Lipkowitz S.
PLoS One 7(11):e49428. doi: 10.1371/journal.pone.0049428. Epub 2012 Nov 7. 2012
3CBLC
Structural flexibility regulates phosphopeptide-binding activity of the tyrosine kinase binding domain of Cbl-c.
Takeshita K, Tezuka T, Isozaki Y, Yamashita E, Suzuki M, Kim M, Yamanashi Y, Yamamoto T, Nakagawa A.
J Biochem 152(5):487-95. doi: 10.1093/jb/mvs085. Epub 2012 Aug 9. 2012
4CBLC
The N terminus of Cbl-c regulates ubiquitin ligase activity by modulating affinity for the ubiquitin-conjugating enzyme.
Ryan PE, Sivadasan-Nair N, Nau MM, Nicholas S, Lipkowitz S.
J Biol Chem 285(31):23687-98. doi: 10.1074/jbc.M109.091157. Epub 2010 Jun 4. 2010
5CBLC, CD2AP, RET
CD2AP and Cbl-3/Cbl-c constitute a critical checkpoint in the regulation of ret signal transduction.
Tsui CC, Pierchala BA.
J Neurosci 28(35):8789-800. doi: 10.1523/JNEUROSCI.2738-08.2008. 2008
6CBLC
Regulation of ubiquitin protein ligase activity in c-Cbl by phosphorylation-induced conformational change and constitutive activation by tyrosine to glutamate point mutations.
Kassenbrock CK, Anderson SM.
J Biol Chem 279(27):28017-27. Epub 2004 Apr 26. 2004
7CBLC,SRC
Cbl-c suppresses v-Src-induced transformation through ubiquitin-dependent protein degradation.
Kim M, Tezuka T, Tanaka K, Yamamoto T.
Oncogene 23(9):1645-55. Erratum in: Oncogene. 2004 Oct 14;23(47):7903-4. 2004
8CBLC, SPRED3
Mutation analysis of CBL-C and SPRED3 on 19q in human glioblastoma.
Mizoguchi M, Nutt CL, Louis DN.
Neurogenetics 5(1):81-2. Epub 2003 Nov 14. No abstract available. 2004
9CBL, CBLB, CBLC
Comparative genomic organization of the cbl genes.
Nau MM, Lipkowitz S.
Gene 308:103-13. 2003
10CBLC
c-Cbl is involved in Met signaling in B cells and mediates hepatocyte growth factor-induced receptor ubiquitination.
Taher TE, Tjin EP, Beuling EA, Borst J, Spaargaren M, Pals ST.
J Immunol 169(7):3793-800. 2002
11CBLC
Molecular cloning and characterization of a novel cbl-family gene, cbl-c.
Kim M, Tezuka T, Suziki Y, Sugano S, Hirai M, Yamamoto T.
Gene 239(1):145-54 1999
12CBLC
cbl-3: a new mammalian cbl family protein.
Keane MM, Ettenberg SA, Nau MM, Banerjee P, Cuello M, Penninger J, Lipkowitz S.
Oncogene 18(22):3365-75. 1999