Citations for
1CBLB
NF-κB downregulates Cbl-b through binding and suppressing Cbl-b promoter in T cell activation.
Liu Y, Li Y, Zhang L, Li M, Li C, Xue C, Huang X, Zhou P.
J Immunol 194(8):3778-83. doi: 10.4049/jimmunol.1402104. Epub 2015 Mar 11. 2015
2CBLB, ORMDL3, STAT6
E3 ubiquitin ligase Cbl-b suppresses human ORMDL3 expression through STAT6 mediation.
Yang WX, Jin R, Jiang CM, Wang XH, Shu J, Li L, Zhu LH, Zhuang LL, Gao C, Zhou GP.
FEBS Lett 589(15):1975-80. doi: 10.1016/j.febslet.2015.06.015. Epub 2015 Jun 22. 2015
3CBLB
Recruitment of Cbl-b to B cell antigen receptor couples antigen recognition to Toll-like receptor 9 activation in late endosomes.
Veselits M, Tanaka A, Lipkowitz S, O'Neill S, Sciammas R, Finnegan A, Zhang J, Clark MR.
PLoS One 9(3):e89792. doi: 10.1371/journal.pone.0089792. eCollection 2014. 2014
4CBL, CBLB, SIRT2
Cbl regulates the activity of SIRT2.
Choi YH, Kim H, Han Y, Jin YH, Lee KY.
Biochem Biophys Res Commun 453(3):557-62. doi: 10.1016/j.bbrc.2014.09.125. Epub 2014 Oct 5. 2014
5CBLB, PTK2B
Cbl-b accelerates trypsin-induced cell detachment through ubiquitination and degradation of proline-rich tyrosine kinase 2.
Fan Y, Qu X, Ma Y, Qu J, Liu Y, Hu X.
Tumour Biol 35(11):11129-35. doi: 10.1007/s13277-014-2296-z. Epub 2014 Aug 7. 2014
6CBLB, DDR2
Ubiquitin ligase Cbl-b acts as a negative regulator in discoidin domain receptor 2 signaling via modulation of its stability.
Yu J, Zhao H, Zhang Y, Liu YC, Yao L, Li X, Su J.
FEBS Lett 588(9):1509-14. doi: 10.1016/j.febslet.2014.03.003. Epub 2014 Mar 12. 2014
7CBLB, SMAD7
Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells.
Gruber T, Hinterleitner R, Hermann-Kleiter N, Meisel M, Kleiter I, Wang CM, Viola A, Pfeifhofer-Obermair C, Baier G.
J Mol Cell Biol 5(6):358-68. doi: 10.1093/jmcb/mjt017. Epub 2013 May 24. 2013
8CBLB
T cell activation threshold regulated by E3 ubiquitin ligase Cbl-b determines fate of inducible regulatory T cells.
Qiao G, Zhao Y, Li Z, Tang PQ, Langdon WY, Yang T, Zhang J.
J Immunol 191(2):632-9. doi: 10.4049/jimmunol.1202068. Epub 2013 Jun 7. 2013
9CBLB, CLEC4G
Up-regulation of Cbl-b is associated with LSECtin-mediated inhibition of different CD4+ T-cell subsets.
Zhao D, Zhang M, Wang M, Liu B, Wang X, Yang J, He F, Tang L.
Immunobiology 218(4):602-8. doi: 10.1016/j.imbio.2012.07.017. Epub 2012 Jul 23. 2013
10CBLB, PTEN
E3 ubiquitin ligase Cbl-b regulates Pten via Nedd4 in T cells independently of its ubiquitin ligase activity.
Guo H, Qiao G, Ying H, Li Z, Zhao Y, Liang Y, Yang L, Lipkowitz S, Penninger JM, Langdon WY, Zhang J.
Cell Rep 1(5):472-82. 2012
11CBLB
Essential role of E3 ubiquitin ligase activity in Cbl-b-regulated T cell functions.
Paolino M, Thien CB, Gruber T, Hinterleitner R, Baier G, Langdon WY, Penninger JM.
J Immunol 186(4):2138-47. doi: 10.4049/jimmunol.1003390. Epub 2011 Jan 19. 2011
12CBLB
Association of the CBLB gene with multiple sclerosis: new evidence from a replication study in an Italian population.
Corrado L, Bergamaschi L, Barizzone N, Fasano ME, Guerini FR, Salvetti M, Galimberti D, Benedetti MD, Leone M, D'Alfonso S.
J Med Genet 48(3):210-1. doi: 10.1136/jmg.2010.081380. Epub 2010 Oct 30. 2011
13CBLB
Cbl-b enhances Runx2 protein stability and augments osteocalcin promoter activity in osteoblastic cell lines.
Salingcarnboriboon RA, Pavasant P, Noda M.
J Cell Physiol 224(3):743-7. doi: 10.1002/jcp.22176. 2010
14CBLB
The E3 ubiquitin ligase Cbl-b regulates expansion but not functional activity of self-reactive CD4 T cells.
St Rose MC, Qui HZ, Bandyopadhyay S, Mihalyo MA, Hagymasi AT, Clark RB, Adler AJ.
J Immunol 183(8):4975-83. doi: 10.4049/jimmunol.0901243. 2009
15CBL, CBLB
Loss of Cbl-b increases osteoclast bone-resorbing activity and induces osteopenia.
Nakajima A, Sanjay A, Chiusaroli R, Adapala NS, Neff L, Itzsteink C, Horne WC, Baron R.
J Bone Miner Res 24(7):1162-72. doi: 10.1359/jbmr.090205. 2009
16CBLB
Identification and functional analysis of CBLB mutations in type 1 diabetes.
Yokoi N, Fujiwara Y, Wang HY, Kitao M, Hayashi C, Someya T, Kanamori M, Oiso Y, Tajima N, Yamada Y, Seino Y, Ikegami H, Seino S.
Biochem Biophys Res Commun 368(1):37-42. Epub 2008 Jan 15. 2008
17CBLB
E3 ubiquitin ligase Cblb regulates the acute inflammatory response underlying lung injury.
Bachmaier K, Toya S, Gao X, Triantafillou T, Garrean S, Park GY, Frey RS, Vogel S, Minshall R, Christman JW, Tiruppathi C, Malik AB.
Nat Med 13(8):920-6. Epub 2007 Jul 8. 2007
18CBL, CBLB, CBLC
Comparative genomic organization of the cbl genes.
Nau MM, Lipkowitz S.
Gene 308:103-13. 2003
19CBLB, CD28
Cbl-b regulates the CD28 dependence of T-cell activation.
Chiang YJ, Kole HK, Brown K, Naramura M, Fukuhara S, Hu RJ, Jang IK, Gutkind JS, Shevach E, Gu H.
Nature 403(6766):216-20 2000
20CBLB
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b.
Bachmaier K, Krawczyk C, Kozieradzki I, Kong YY, Sasaki T, Oliveira-dos-Santos A, Mariathasan S, Bouchard D, Wakeham A, Itie A, Le J, Ohashi PS, Sarosi I, Nishina H, Lipkowitz S, Penninger JM.
Nature 403(6766):211-6 2000
21CBLB
Cloning and characterization of cbl-b : a SH3 binding protein with homology to the c-cbl proto-oncogene.
Keane MM, et al.
Oncogene 10 : 2367-2377. 1995