Citations for
1CASP8AP2, CTBP2
Low expression of CTBP2 and CASP8AP2 predicts risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia: a retrospective cohort study
Cui L, Gao C, Wang CJ, Liu SG, Wu MY, Zhang RD, Li ZG.
Pediatr Hematol Oncol. Aug 17:1-15. doi: 10.1080/08880018.2020.1798572. Epub ahead of print. 2020
2CASP8AP2, INPP5D
The tumor suppressor SHIP1 colocalizes in nucleolar cavities with p53 and components of PML nuclear bodies.
Ehm P, Nalaskowski MM, Wundenberg T, Jücker M.
Nucleus 6(2):154-64. doi: 10.1080/19491034.2015.1022701. 2015
3CASP8AP2
SUMO regulates proteasome-dependent degradation of FLASH/Casp8AP2.
Vennemann A, Hofmann TG.
Cell Cycle 12(12):1914-21. doi: 10.4161/cc.24943. Epub 2013 May 13. 2013
4CASP8AP2, TP73
FLASH is essential during early embryogenesis and cooperates with p73 to regulate histone gene transcription.
De Cola A, Bongiorno-Borbone L, Bianchi E, Barcaroli D, Carletti E, Knight RA, Di Ilio C, Melino G, Sette C, De Laurenzi V.
Oncogene 31(5):573-82. doi: 10.1038/onc.2011.274. Epub 2011 Jul 4. 2012
5CASP8AP2
Targeted Casp8AP2 methylation increases drug resistance in mesenchymal stem cells and cancer cells.
Lee KD, Pai MY, Hsu CC, Chen CC, Chen YL, Chu PY, Lee CH, Chen LT, Chang JY, Huang TH, Hsiao SH, Leu YW.
Biochem Biophys Res Commun 422(4):578-85. doi: 10.1016/j.bbrc.2012.05.029. Epub 2012 May 14. 2012
6CASP8AP2
FLASH knockdown sensitizes cells to Fas-mediated apoptosis via down-regulation of the anti-apoptotic proteins, MCL-1 and Cflip short.
Chen S, Evans HG, Evans DR.
PLoS One 7(3):e32971. doi: 10.1371/journal.pone.0032971. Epub 2012 Mar 9. 2012
7CASP8AP2
CASP8AP2 is a promising prognostic indicator in pediatric acute lymphoblastic leukemia.
Jiao Y, Cui L, Gao C, Li W, Zhao X, Liu S, Wu M, Deng G, Li Z.
Leuk Res 36(1):67-71. doi: 10.1016/j.leukres.2011.05.023. Epub 2011 Jun 21. 2012
8CASP8AP2, CPSF3, LSM11
FLASH is required for the endonucleolytic cleavage of histone pre-mRNAs but is dispensable for the 5' exonucleolytic degradation of the downstream cleavage product.
Yang XC, Xu B, Sabath I, Kunduru L, Burch BD, Marzluff WF, Dominski Z.
Mol Cell Biol 31(7):1492-502. Epub 2011 Jan 18. 2011
9CASP8AP2, MYB, PIAS1
PIAS1 interacts with FLASH and enhances its co-activation of c-Myb.
Alm-Kristiansen AH, Lorenzo PI, Molværsmyr AK, Matre V, Ledsaak M, Sæther T, Gabrielsen OS.
Mol Cancer 10:21. doi: 10.1186/1476-4598-10-21. 2011
10CASP8AP2
Cytoplasmic relocation of Daxx induced by Ro52 and FLASH.
Tanaka M, Kamitani T.
Histochem Cell Biol 134(3):297-306. doi: 10.1007/s00418-010-0734-6. Epub 2010 Aug 10. 2010
11CASP8AP2
Genetic variation in caspase genes and risk of non-Hodgkin lymphoma: a pooled analysis of three population-based case-control studies.
Lan Q, Morton LM, Armstrong B, Hartge P, Menashe I, Zheng T, Purdue MP, Cerhan JR, Zhang Y, Grulich A, Cozen W, Yeager M, Holford TR, Vajdic CM, Davis S, Leaderer B, Kricker A, Schenk M, Zahm SH, Chatterjee N, Chanock SJ, Rothman N, Wang SS.
Blood lood. 2009 May 4. [Epub ahead of print] 2009
12CASP8AP2
SUMO modification regulates the transcriptional activity of FLASH.
Alm-Kristiansen AH, Norman IL, Matre V, Gabrielsen OS.
Biochem Biophys Res Commun 387(3):494-9. Epub 2009 Jul 16. 2009
13CASP8AP2, SRRT
Interaction of FLASH with arsenite resistance protein 2 is involved in cell cycle progression at S phase.
Kiriyama M, Kobayashi Y, Saito M, Ishikawa F, Yonehara S.
Mol Cell Biol 29(17):4729-41. Epub 2009 Jun 22. 2009
14CASP8AP2
FLASH and NPAT positive but not Coilin positive Cajal Bodies correlate with cell ploidy.
Bongiorno-Borbone L, De Cola A, Vernole P, Finos L, Barcaroli D, Knight RA, Melino G, De Laurenzi V.
Cell Cycle 7(15):2357-67. Epub 2008 May 21. 2008
15CASP8AP2, MYB, POLR2A
FLASH acts as a co-activator of the transcription factor c-Myb and localizes to active RNA polymerase II foci.
Alm-Kristiansen AH, Saether T, Matre V, Gilfillan S, Dahle O, Gabrielsen OS.
Oncogene 27(34):4644-56. Epub 2008 Apr 14. 2008
16CASP8AP2
Mutational analysis of FLASH and PTPN13 genes in colorectal carcinomas.
Jeong EG, Lee SH, Yoo NJ, Lee SH.
Pathology 40(1):31-4. 2008
17CASP8AP2, FAS
FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies.
Milovic-Holm K, Krieghoff E, Jensen K, Will H, Hofmann TG.
EMBO J 26(2):391-401. 2007
18CASP8AP2
FLASH is required for histone transcription and S-phase progression.
Barcaroli D, Bongiorno-Borbone L, Terrinoni A, Hofmann TG, Rossi M, Knight RA, Matera AG, Melino G, De Laurenzi V.
Proc Natl Acad Sci U S A 103(40):14808-12. Epub 2006 Sep 26. 2006
19CASP8AP2
FLASH is an essential component of Cajal bodies.
Barcaroli D, Dinsdale D, Neale MH, Bongiorno-Borbone L, Ranalli M, Munarriz E, Sayan AE, McWilliam JM, Smith TM, Fava E, Knight RA, Melino G, De Laurenzi V.
Proc Natl Acad Sci U S A 103(40):14802-7. Epub 2006 Sep 26. 2006
20CASP8AP2
Role of FLASH in caspase-8-mediated activation of NF-kappaB: dominant-negative function of FLASH mutant in NF-kappaB signaling pathway.
Jun JI, Chung CW, Lee HJ, Pyo JO, Lee KN, Kim NS, Kim YS, Yoo HS, Lee TH, Kim E, Jung YK.
Oncogene 24(4):688-96. 2005
21AP1S1, ATP6V1D, BM22, CASP8AP2, CDC16, CDC27, CENPE, CLDN16, CMTM4, CYTH3, DDX5, DHX8, EIF3A, EIF3H, EIF4A3, GALNT5, ITPR1, KIF11, KPNB1, LSM6, MFAP1, NCAPD3, NCAPG2, RBM19, RRM2, SART1, SNRPA1, SNRPB, SNW1, SPC25, VCP, ZDHHC5
An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division.
Kittler R, Putz G, Pelletier L, Poser I, Heninger AK, Drechsel D, Fischer S, Konstantinova I, Habermann B, Grabner H, Yaspo ML, Himmelbauer H, Korn B, Neugebauer K, Pisabarro MT, Buchholz F.
Nature 432(7020):1036-40. 2004
22CASP8AP2
FLASH coordinates NF-kappa B activity via TRAF2.
Choi YH, Kim KB, Kim HH, Hong GS, Kwon YK, Chung CW, Park YM, Shen ZJ, Kim BJ, Lee SY, Jung YK.
J Biol Chem 276(27):25073-7. 2001
23CASP8AP2
The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis.
Imai Y, Kimura T, Murakami A, Yajima N, Sakamaki K, Yonehara S.
Nature 398(6730):777-85. 1999