| 1 | CASP8, N4BP1
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| Integration of innate immune signalling by caspase-8 cleavage of N4BP1
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| Gitlin AD, Heger K, Schubert AF, Reja R, Yan D, Pham VC, Suto E, Zhang J, Kwon YC, Freund EC, Kang J, Pham A, Caothien R, Bacarro N, Hinkle T, Xu M, McKenzie BS, Haley B, Lee WP, Lill JR, Roose-Girma M, Dohse M, Webster JD, Newton K, Dixit VM.
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| Nature. Nov;587(7833):275-280. doi: 10.1038/s41586-020-2796-5. Epub 2020 Sep 24. 2020
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| 2 | CASP8, PLK1, RIPK1
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| RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation.
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| Liccardi G, Ramos Garcia L, Tenev T, Annibaldi A, Legrand AJ, Robertson D, Feltham R, Anderton H, Darding M, Peltzer N, Dannappel M, Schünke H, Fava LL, Haschka MD, Glatter T, Nesvizhskii A, Schmidt A, Harris PA, Bertin J, Gough PJ, Villunger A, Silke J, Pasparakis M, Bianchi K, Meier P.
|
| Mol Cell 73(3):413-428.e7. doi: 10.1016/j.molcel.2018.11.010. Epub 2018 Dec 28.
2019
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| 3 | CASP8, TNFRSF10B
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| Confirming a critical role for death receptor 5 and caspase-8 in apoptosis induction by endoplasmic reticulum stress.
|
| Lam M, Lawrence DA, Ashkenazi A, Walter P.
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| Cell Death Differ. Aug;25(8):1530-1531. doi: 10.1038/s41418-018-0155-y. Epub 2018 Jul 10 2019
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| 4 | CASP8, SCAF11
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| Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock.
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| Mandal P, Feng Y, Lyons JD, Berger SB, Otani S, DeLaney A, Tharp GK, Maner-Smith K, Burd EM, Schaeffer M, Hoffman S, Capriotti C, Roback L, Young CB, Liang Z, Ortlund EA, DiPaolo NC, Bosinger S, Bertin J, Gough PJ, Brodsky IE, Coopersmith CM, Shayakhmetov DM, Mocarski ES.
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| Immunity 49(1):42-55.e6. doi: 10.1016/j.immuni.2018.06.011.
2018
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| 5 | CASP8, CFLAR
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| Induction of immunosuppressive functions and NF-κB by FLIP in monocytes.
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| Fiore A, Ugel S, De Sanctis F, Sandri S, Fracasso G, Trovato R, Sartoris S, Solito S, Mandruzzato S, Vascotto F, Hippen KL, Mondanelli G, Grohmann U, Piro G, Carbone C, Melisi D, Lawlor RT, Scarpa A, Lamolinara A, Iezzi M, Fassan M, Bicciato S, Blazar BR, Sahin U, Murray PJ, Bronte V.
|
| Nat Commun. Dec 5;9(1):5193. doi: 10.1038/s41467-018-07654-4. 2018
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| 6 | CASP3, CASP8
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| Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants.
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| Rehker J, Rodhe J, Nesbitt RR, Boyle EA, Martin BK, Lord J, Karaca I, Naj A, Jessen F, Helisalmi S, Soininen H, Hiltunen M, Ramirez A, Scherer M, Farrer LA, Haines JL, Pericak-Vance MA, Raskind WH, Cruchaga C, Schellenberg GD, Joseph B, Brkanac Z.
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| PLoS One 12(10):e0185777. doi: 10.1371/journal.pone.0185777. eCollection 2017.
2017
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| 7 | CASP8
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| Caspase-8: regulating life and death.
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| Tummers B, Green DR.
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| Immunol Rev 277(1):76-89. doi: 10.1111/imr.12541. Review.
2017
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| 8 | CASP10, CASP8, CFLAR
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| Caspase-10 Negatively Regulates Caspase-8-Mediated Cell Death, Switching the Response to CD95L in Favor of NF-κB Activation and Cell Survival.
|
| Horn S, Hughes MA, Schilling R, Sticht C, Tenev T, Ploesser M, Meier P, Sprick MR, MacFarlane M, Leverkus M.
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| Cell Rep 19(4):785-797. doi: 10.1016/j.celrep.2017.04.010.
2017
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| 9 | CASP8, TNFSF10
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| Correlation between TRAIL and caspase-8 expression and their relationship with cell proliferation and apoptosis in human osteosarcoma.
|
| Ning X, Shang XW, Zhuang Y, Liu M, Yang H, Zhang H, Huang MZ.
|
| Genet Mol Res 15(4). doi: 10.4238/gmr15048876.
2016
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| 10 | CASP8, CFLAR
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| Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death.
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| Philip NH, DeLaney A, Peterson LW, Santos-Marrero M, Grier JT, Sun Y, Wynosky-Dolfi MA, Zwack EE, Hu B, Olsen TM, Rongvaux A, Pope SD, López CB, Oberst A, Beiting DP, Henao-Mejia J, Brodsky IE.
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| PLoS Pathog 12(10):e1005910. doi: 10.1371/journal.ppat.1005910. eCollection 2016 Oct.
2016
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| 11 | CASP8, MAP3K7, TRADD
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| TAK1 regulates caspase 8 activation and necroptotic signaling via multiple cell death checkpoints.
|
| Guo X, Yin H, Chen Y, Li L, Li J, Liu Q.
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| Cell Death Dis 7(9):e2381. doi: 10.1038/cddis.2016.294.
2016
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| 12 | CASP8
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| Caspase-8 tyrosine-380 phosphorylation inhibits CD95 DISC function by preventing procaspase-8 maturation and cycling within the complex.
|
| Powley IR, Hughes MA, Cain K, MacFarlane M.
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| Oncogene 35(43):5629-5640. doi: 10.1038/onc.2016.99. Epub 2016 Apr 25.
2016
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| 13 | CASP8
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| Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner.
|
| Cuda CM, Misharin AV, Khare S, Saber R, Tsai F, Archer AM, Homan PJ, Haines GK 3rd, Hutcheson J, Dorfleutner A, Budinger GR, Stehlik C, Perlman H.
|
| Arthritis Res Ther 17:291. doi: 10.1186/s13075-015-0794-z.
2015
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| 14 | CASP1, CASP8, IL1B
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| Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling.
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| Antonopoulos C, Russo HM, El Sanadi C, Martin BN, Li X, Kaiser WJ, Mocarski ES, Dubyak GR.
|
| J Biol Chem 290(33):20167-84. doi: 10.1074/jbc.M115.652321. Epub 2015 Jun 22.
2015
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| 15 | CASP8, EPHA7
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| EphA receptors form a complex with caspase-8 to induce apoptotic cell death.
|
| Lee H, Park S, Kang YS, Park S.
|
| Mol Cells 38(4):349-55. doi: 10.14348/molcells.2015.2279.
2015
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| 16 | CASP8, RIPK3
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| A RIPK3-caspase 8 complex mediates atypical pro-IL-1β processing.
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| Moriwaki K, Bertin J, Gough PJ, Chan FK.
|
| J Immunol 194(4):1938-44. doi: 10.4049/jimmunol.1402167. Epub 2015 Jan 7.
2015
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| 17 | CASP8, TLR4, TNFAIP8L2
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| A novel inflammatory regulator TIPE2 inhibits TLR4-mediated development of colon cancer via caspase-8.
|
| Li XM, Su JR, Yan SP, Cheng ZL, Yang TT, Zhu Q.
|
| Cancer Biomark 14(4):233-40. doi: 10.3233/CBM-140402.
2014
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| 18 | CASP8, FAT1
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| A synthetic lethal screen identifies FAT1 as an antagonist of caspase-8 in extrinsic apoptosis.
|
| Kranz D, Boutros M.
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| EMBO J 33(3):181-97. doi: 10.1002/embj.201385686.
2014
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| 19 | CASP8, ERN1, RIPK1
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| RIPK1 promotes death receptor-independent caspase-8-mediated apoptosis under unresolved ER stress conditions.
|
| Estornes Y, Aguileta MA, Dubuisson C, De Keyser J, Goossens V, Kersse K, Samali A, Vandenabeele P, Bertrand MJ.
|
| Cell Death Dis 5:e1555. doi: 10.1038/cddis.2014.523. Erratum in: Cell Death Dis. 2015;6:e1798.
2014
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| 20 | CASP8, PAWR, TNF
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| Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis.
|
| Treude F, Kappes F, Fahrenkamp D, Müller-Newen G, Dajas-Bailador F, Krämer OH, Lüscher B, Hartkamp J.
|
| Oncotarget 5(10):2988-98.
2014
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| 21 | CASP8, RIPK1, RIPK3
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| RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3.
|
| Dillon CP, Weinlich R, Rodriguez DA, Cripps JG, Quarato G, Gurung P, Verbist KC, Brewer TL, Llambi F, Gong YN, Janke LJ, Kelliher MA, Kanneganti TD, Green DR.
|
| Cell 157(5):1189-202. doi: 10.1016/j.cell.2014.04.018. Epub 2014 May 8.
2014
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| 22 | CASP8, RIPK3, TLR3
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| Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL.
|
| Kaiser WJ, Sridharan H, Huang C, Mandal P, Upton JW, Gough PJ, Sehon CA, Marquis RW, Bertin J, Mocarski ES.
|
| J Biol Chem 288(43):31268-79. doi: 10.1074/jbc.M113.462341. Epub 2013 Sep 9.
2013
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| 23 | CASP8, IRF1, SMAD7
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| Smad7 protein induces interferon regulatory factor 1-dependent transcriptional activation of caspase 8 to restore tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis.
|
| Hong S, Kim HY, Kim J, Ha HT, Kim YM, Bae E, Kim TH, Lee KC, Kim SJ.
|
| J Biol Chem 288(5):3560-70. doi: 10.1074/jbc.M112.400408. Epub 2012 Dec 19. 2013
|
| 24 | CASP8, TRAF2
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| TRAF2 Sets a threshold for extrinsic apoptosis by tagging caspase-8 with a ubiquitin shutoff timer.
|
| Gonzalvez F, Lawrence D, Yang B, Yee S, Pitti R, Marsters S, Pham VC, Stephan JP, Lill J, Ashkenazi A.
|
| Mol Cell 48(6):888-99. doi: 10.1016/j.molcel.2012.09.031. Epub 2012 Nov 8.
2012
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| 25 | CASP10, CASP8
|
| Advances in Autoimmune Lymphoproliferative Syndromes (ALPS).
|
| Madkaikar M, Mhatre S, Gupta M, Ghosh K.
|
| Eur J Haematol ur J Haematol. 2011 Mar 29. doi: 10.1111/j.1600-0609.2011.01617.x. [Epub ahead of print]
2011
|
| 26 | CASP10, CASP8
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| Individual caspase-10 isoforms play distinct and opposing roles in the initiation of death receptor-mediated tumour cell apoptosis.
|
| Mühlethaler-Mottet A, Flahaut M, Bourloud KB, Nardou K, Coulon A, Liberman J, Thome M, Gross N.
|
| Cell Death Dis 2(1):e125.
2011
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| 27 | CASP8, DDX58, IRF3, RIPK1
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| RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein.
|
| Rajput A, Kovalenko A, Bogdanov K, Yang SH, Kang TB, Kim JC, Du J, Wallach D.
|
| Immunity 34(3):340-51.
2011
|
| 28 | CASP8, IRF3
|
| Caspase-8-mediated cleavage inhibits IRF-3 protein by facilitating its proteasome-mediated degradation.
|
| Sears N, Sen GC, Stark GR, Chattopadhyay S.
|
| J Biol Chem 286(38):33037-44. Epub 2011 Aug 4.
2011
|
| 29 | CASP8, FADD, FAS, ORAI1
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| CD95 triggers Orai1-mediated localized Ca2+ entry, regulates recruitment of protein kinase C (PKC) β2, and prevents death-inducing signaling complex formation.
|
| Khadra N, Bresson-Bepoldin L, Penna A, Chaigne-Delalande B, Ségui B, Levade T, Vacher AM, Reiffers J, Ducret T, Moreau JF, Cahalan MD, Vacher P, Legembre P.
|
| Proc Natl Acad Sci U S A 108(47):19072-7. doi: 10.1073/pnas.1116946108. Epub 2011 Nov 7.
2011
|
| 30 | CASP8, CYLD
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| Caspase 8 inhibits programmed necrosis by processing CYLD.
|
| O'Donnell MA, Perez-Jimenez E, Oberst A, Ng A, Massoumi R, Xavier R, Green DR, Ting AT.
|
| Nat Cell Biol 13(12):1437-42. doi: 10.1038/ncb2362.
2011
|
| 31 | CASP8, CFLAR
|
| Caspase-8, c-FLIP, and caspase-9 in c-Myc-induced apoptosis of fibroblasts.
|
| Järvinen K, Hotti A, Santos L, Nummela P, Hölttä E.
|
| Exp Cell Res 317(18):2602-15. doi: 10.1016/j.yexcr.2011.08.014. Epub 2011 Aug 28.
2011
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| 32 | CASP8, RIPK3
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| Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis.
|
| Oberst A, Dillon CP, Weinlich R, McCormick LL, Fitzgerald P, Pop C, Hakem R, Salvesen GS, Green DR.
|
| Nature 471(7338):363-7. doi: 10.1038/nature09852. Epub 2011 Mar 2.
2011
|
| 33 | CASP8, FADD
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| Fas-associated death domain (FADD) is a negative regulator of T-cell receptor-mediated necroptosis.
|
| Osborn SL, Diehl G, Han SJ, Xue L, Kurd N, Hsieh K, Cado D, Robey EA, Winoto A.
|
| Proc Natl Acad Sci U S A 107(29):13034-9. Epub 2010 Jul 6.PMID: 20615958 2010
|
| 34 | CASP10, CASP8
|
| Activation and specificity of human caspase-10.
|
| Wachmann K, Pop C, van Raam BJ, Drag M, Mace PD, Snipas SJ, Zmasek C, Schwarzenbacher R, Salvesen GS, Riedl SJ.
|
| Biochemistry 49(38):8307-15.
2010
|
| 35 | CASP8, NOD2
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| Caspase recruitment domain-containing protein 8 (CARD8) negatively regulates NOD2-mediated signaling.
|
| von Kampen O, Lipinski S, Till A, Martin SJ, Nietfeld W, Lehrach H, Schreiber S, Rosenstiel P.
|
| J Biol Chem 285(26):19921-6. doi: 10.1074/jbc.M110.127480. Epub 2010 Apr 12.
2010
|
| 36 | CASP1, CASP10, CASP14, CASP2, CASP3, CASP4, CASP5, CASP6, CASP7, CASP8, CASP9
|
| Mutational analysis of CASP1, 2, 3, 4, 5, 6, 7, 8, 9, 10, and 14 genes in gastrointestinal stromal tumors.
|
| Kim YR, Kim KM, Yoo NJ, Lee SH.
|
| Hum Pathol 40(6):868-71. Epub 2009 Mar 9.
2009
|
| 37 | CASP8, EGF
|
| Critical role for caspase-8 in epidermal growth factor signaling.
|
| Finlay D, Howes A, Vuori K.
|
| Cancer Res 69(12):5023-9. Epub 2009 May 26.
2009
|
| 38 | CASP10, CASP8, HSP90AB1
|
| Caspase-10-mediated heat shock protein 90 beta cleavage promotes UVB irradiation-induced cell apoptosis.
|
| Chen H, Xia Y, Fang D, Hawke D, Lu Z.
|
| Mol Cell Biol 29(13):3657-64. Epub 2009 Apr 20.
2009
|
| 39 | CASP1, CASP8, IL33
|
| Caspase-1, caspase-8, and calpain are dispensable for IL-33 release by macrophages.
|
| Ohno T, Oboki K, Kajiwara N, Morii E, Aozasa K, Flavell RA, Okumura K, Saito H, Nakae S.
|
| J Immunol 183(12):7890-7. Epub .
2009
|
| 40 | CASP8
|
| A promoter polymorphism in the CASP8 gene is not associated with cancer risk.
|
| Haiman CA, Garcia RR, Kolonel LN, Henderson BE, Wu AH, Le Marchand L.
|
| Nat Genet 40(3):259-60; author reply 260-1. No abstract available. 2008
|
| 41 | ATG5, CASP8, FADD
|
| FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells.
|
| Bell BD, Leverrier S, Weist BM, Newton RH, Arechiga AF, Luhrs KA, Morrissette NS, Walsh CM.
|
| Proc Natl Acad Sci U S A 105(43):16677-82. Epub 2008 Oct 22.
2008
|
| 42 | CASP8, RAB5A
|
| Caspase 8 promotes peripheral localization and activation of Rab5.
|
| Torres VA, Mielgo A, Barilà D, Anderson DH, Stupack D.
|
| J Biol Chem 283(52):36280-9. Epub 2008 Oct 29.
2008
|
| 43 | CASP10, CASP8
|
| Clinicopathological significance of caspase-8 and caspase-10 expression in rectal cancer.
|
| Xu B, Zhou ZG, Li Y, Wang L, Yang L, Zhou B, Liu HY, Song JM, Zeng YJ, Wang R, Shen XG, Sun XF.
|
| Oncology 74(3-4):229-36. Epub 2008 Aug 21.
2008
|
| 44 | ABCF1, AKAP1, CASP10, CASP8, CPE, GOPC
|
| Genome-wide screening and identification of novel proteolytic cleavage targets of caspase-8 and -10 in vitro.
|
| Bae S, Ha TS, Yoon Y, Lee J, Cha HJ, Yoo H, Choe TB, Li S, Sohn I, Kim JY, Kim CS, Jin HO, Lee HC, Park IC, Kim CS, Jin YW, Ahn SK.
|
| Int J Mol Med 21(3):381-6.
2008
|
| 45 | CASP8
|
| A common coding variant in CASP8 is associated with breast cancer risk.
|
| Cox A, Dunning AM, Garcia-Closas M, Balasubramanian S, Reed MW, Pooley KA, Scollen S, Baynes C, Ponder BA, Chanock S, Lissowska J, Brinton L, Peplonska B, Southey MC, Hopper JL, McCredie MR, Giles GG, Fletcher O, Johnson N, Dos Santos Silva I, Gibson L, Bojesen SE, Nordestgaard BG, Axelsson CK, Torres D, Hamann U, Justenhoven C, Brauch H, Chang-Claude J, Kropp S, Risch A, Wang-Gohrke S, Schurmann P, Bogdanova N, Dork T, Fagerholm R, Aaltonen K, Blomqvist C, Nevanlinna H, Seal S, Renwick A, Stratton MR, Rahman N, Sangrajrang S, Hughes D, Odefrey F, Brennan P, Spurdle AB, Chenevix-Trench G; The Kathleen Cunningham Foundation Consortium for Research into Familial Breast Cancer; Beesley J, Mannermaa A, Hartikainen J, Kataja V, Kosma VM, Couch FJ, Olson JE, Goode EL, Broeks A, Schmidt MK, Hogervorst FB, Veer LJ, Kang D, Yoo KY, Noh DY, Ahn SH, Wedren S, Hall P, Low YL, Liu J, Milne RL, Ribas G, Gonzalez-Neira A, Benitez J, Sigurdson AJ, Stredrick DL, Alexander BH, Struewing JP, Pharoah PD, Easton DF; on behalf of the Breast Cancer Association Consortium.
|
| Nat Genet 39(3):352-8. Epub 2007 Feb 11. 2007
|
| 46 | CASP3, CASP8, CASP12
|
| Caspase-8, -12, and -3 activation by 7-ketocholesterol in retinal neurosensory cells.
|
| Neekhra A, Luthra S, Chwa M, Seigel G, Gramajo AL, Kuppermann BD, Kenney MC.
|
| Invest Ophthalmol Vis Sci 48(3):1362-7. 2007
|
| 47 | CASP8
|
| Polymorphisms in the caspase-8 gene and the risk of lung cancer.
|
| Son JW, Kang HK, Chae MH, Choi JE, Park JM, Lee WK, Kim CH, Kim DS, Kam S, Kang YM, Park JY.
|
| Cancer Genet Cytogenet 169(2):121-7. 2006
|
| 48 | CASP3, CASP8, CASP12
|
| Activation of caspase-8 and caspase-12 pathways by 7-ketocholesterol in human retinal pigment epithelial cells.
|
| Luthra S, Fardin B, Dong J, Hertzog D, Kamjoo S, Gebremariam S, Butani V, Narayanan R, Mungcal JK, Kuppermann BD, Kenney MC.
|
| Invest Ophthalmol Vis Sci 47(12):5569-75. 2006
|
| 49 | CASP8, CASP10
|
| Association of the CASP10 V410I variant with reduced familial breast cancer risk and interaction with the CASP8 D302H variant.
|
| Frank B, Hemminki K, Wappenschmidt B, Meindl A, Klaes R, Schmutzler RK, Bugert P, Untch M, Bartram CR, Burwinkel B.
|
| Carcinogenesis 27(3):606-9. Epub 2005 Oct 26. 2006
|
| 50 | CASP8
|
| Requirement for caspase-8 in NF-kappaB activation by antigen receptor.
|
| Su H, Bidere N, Zheng L, Cubre A, Sakai K, Dale J, Salmena L, Hakem R, Straus S, Lenardo M.
|
| Science 307(5714):1465-8. 2005
|
| 51 | CASP8
|
| Caspase-8 gene is frequently inactivated by the frameshift somatic mutation 1225_1226delTG in hepatocellular carcinomas.
|
| Soung YH, Lee JW, Kim SY, Sung YJ, Park WS, Nam SW, Kim SH, Lee JY, Yoo NJ, Lee SH.
|
| Oncogene 24(1):141-7. 2005
|
| 52 | CASP8
|
| CASPASE-8 gene is inactivated by somatic mutations in gastric carcinomas.
|
| Soung YH, Lee JW, Kim SY, Jang J, Park YG, Park WS, Nam SW, Lee JY, Yoo NJ, Lee SH.
|
| Cancer Res 65(3):815-21. 2005
|
| 53 | BID, CASP8, DIABLO, MAPK8, TNF
|
| A JNK-dependent pathway is required for TNFalpha-induced apoptosis.
|
| Deng Y, Ren X, Yang L, Lin Y, Wu X.
|
| Cell 115(1):61-70. 2003
|
| 54 | CASP8, IFT57, HIP1
|
| Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi.
|
| Gervais FG, Singaraja R, Xanthoudakis S, Gutekunst CA, Leavitt BR, Metzler M, Hackam AS, Tam J, Vaillancourt JP, Houtzager V, Rasper DM, Roy S, Hayden MR, Nicholson DW.
|
| Nat Cell Biol 4(2):95-105. 2002
|
| 55 | CASP8, CASP8D
|
| Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency.
|
| Chun HJ, Zheng L, Ahmad M, Wang J, Speirs CK, Siegel RM, Dale JK, Puck J, Davis J, Hall CG, Skoda-Smith S, Atkinson TP, Straus SE, Lenardo MJ.
|
| Nature 419(6905):395-9. 2002
|
| 56 | CASP8
|
| The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum.
|
| Breckenridge DG, Nguyen M, Kuppig S, Reth M, Shore GC.
|
| Proc Natl Acad Sci U S A 99(7):4331-6. Epub 2002 Mar 26. 2002
|
| 57 | CASP8, TSG2A
|
| Allelic imbalance on chromosome 2q and alterations of the caspase 8 gene in neuroblastoma.
|
| Takita J, Yang HW, Chen YY, Hanada R, Yamamoto K, Teitz T, Kidd V, Hayashi Y.
|
| Oncogene 20(32):4424-32. 2001
|
| 58 | ABI2, AOX1, BMPR2, CASP10, CASP8, CD28, CFLAR, CLK1, CTLA4, DAZAP2, MAGI2, ORC2, PPH1, PSMA2, SATB2, SUMO1, TRAK2
|
| A physical and transcript map based upon refinement of the critical interval for PPH1, a gene for familial primary pulmonary hypertension.
|
| Machado RD, Pauciulo MW, Fretwell N, Veal C, Thomson JR, Vilarino Guell C, Aldred M, Brannon CA, Trembath RC, Nichols WC.
|
| Genomics 68(2):220-8. 2000
|
| 59 | CASP1, CASP4, CASP5, CASP8
|
| Structure and chromosome localization of the human CASP8 gene.
|
| Grenet J, Teitz T, Wei T, Valentine V, Kidd VJ.
|
| Gene 226(2):225-32. 1999
|
| 60 | CASP8
|
| Assignment of CASP8 to human chromosome band 2q33-->q34 and Casp8 to the murine syntenic region on chromosome 1B-proximal C by in situ hybridization.
|
| Kischkel FC, Kioschis P, Weitz S, Poustka A, Lichter P, Krammer PH.
|
| Cytogenet Cell Genet 82(1-2):95-6. 1998
|
| 61 | BID, CASP8
|
| Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis.
|
| Li H, Zhu H, Xu CJ, Yuan J.
|
| Cell 94(4):491-501. 1998
|
| 62 | CASP8
|
| Activation of human monocytes induces differential resistance to apoptosis with rapid down regulation of caspase-8/FLICE.
|
| Perera LP, Waldmann TA.
|
| Proc Natl Acad Sci U S A 95 : 14308-14313. 1998
|
| 63 | CASP1, CASP8, PLA2G1B
|
| Cleavage of human cytosolic phospholipase A2 by caspase-1 (ICE) and caspase-8 (FLICE).
|
| Luschen S, et al.
|
| Biochem Biophys Res Commun 253 : 92-98. 1998
|
| 64 | CASP8
|
| Caspases : the executioners of apoptosis.
|
| Cohen GM.
|
| Biochem J 326 : 1-16. 1997
|
| 65 | CASP10, CASP8, CFLAR
|
| FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis.
|
| Srinivasula SM, Ahmad M, Ottilie S, Bullrich F, Banks S, Wang Y, Fernandes-Alnemri T, Croce CM, Litwack G, Tomaselli KJ, Armstrong RC, Alnemri ES.
|
| J Biol Chem 272(30):18542-5. 1997
|
| 66 | CASP8
|
| FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.
|
| Muzio M, Chinnaiyan AM, Kischkel FC, O'Rourke K, Shevchenko A, Ni J, Scaffidi C, Bretz JD, Zhang M, Gentz R, Mann M, Krammer PH, Peter ME, Dixit VM.
|
| Cell 85(6):817-27. 1996
|
| 67 | CASP8, FADD
|
| Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death.
|
| Boldin MP, Goncharov TM, Goltsev YV, Wallach D.
|
| Cell 85(6):803-15. 1996
|
| 68 | CASP8
|
| Mch3, a novel human apoptotic cysteine protease highly related to CPP32.
|
| Fernandes-Alnemri T, Takahashi A, Armstrong R, Krebs J, Fritz L, Tomaselli KJ, Wang L, Yu Z, Croce CM, Salveson G, et al.
|
| Cancer Res 55(24):6045-52.
1995
|