| 1 | CASP12
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| Regulated expression of caspase-12 gene in human retinal pigment epithelial cells suggests its immunomodulating role.
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| Bian ZM, Elner SG, Elner VM.
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| Invest Ophthalmol Vis Sci. 49(12):5593-601. 2008
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| 2 | CASP12, HSPA5
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| Upregulation of GRP78 and caspase-12 in diastolic failing heart.
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| Sun Y, Liu G, Song T, Liu F, Kang W, Zhang Y, Ge Z.
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| Acta Biochim Pol 55(3):511-6. Epub 2008 Sep 12. 2008
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| 3 | CASP3, CASP8, CASP12
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| Caspase-8, -12, and -3 activation by 7-ketocholesterol in retinal neurosensory cells.
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| Neekhra A, Luthra S, Chwa M, Seigel G, Gramajo AL, Kuppermann BD, Kenney MC.
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| Invest Ophthalmol Vis Sci 48(3):1362-7. 2007
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| 4 | BIK,CASP12
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| Apoptosis induced by BIK was decreased with RNA interference of caspase-12.
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| Zhao X, Sun Y, Yu H, Ye L, Zhang L, Lu J, Yuan Y, Qian G, Ge S.
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| Biochem Biophys Res Commun 359(4):896-901. Epub 2007 Jun 4. 2007
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| 5 | CASP12
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| Population distribution of the functional caspase-12 allele.
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| Kachapati K, O'Brien TR, Bergeron J, Zhang M, Dean M.
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| Hum Mutat 27(9):975. 2006
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| 6 | CASP12
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| Spread of an inactive form of caspase-12 in humans is due to recent positive selection.
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| Xue Y, Daly A, Yngvadottir B, Liu M, Coop G, Kim Y, Sabeti P, Chen Y, Stalker J, Huckle E, Burton J, Leonard S, Rogers J, Tyler-Smith C.
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| Am J Hum Genet 78(4):659-70. Epub 2006 Feb 21. 2006
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| 7 | CASP3, CASP8, CASP12
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| Activation of caspase-8 and caspase-12 pathways by 7-ketocholesterol in human retinal pigment epithelial cells.
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| Luthra S, Fardin B, Dong J, Hertzog D, Kamjoo S, Gebremariam S, Butani V, Narayanan R, Mungcal JK, Kuppermann BD, Kenney MC.
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| Invest Ophthalmol Vis Sci 47(12):5569-75. 2006
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| 8 | CASP12
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| Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice.
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| Saleh M, Mathison JC, Wolinski MK, Bensinger SJ, Fitzgerald P, Droin N, Ulevitch RJ, Green DR, Nicholson DW.
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| Nature 440: 1064-1068 2006
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| 9 | CASP12
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| Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors.
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| Sanges D, Comitato A, Tammaro R, Marigo V.
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| Proc Natl Acad Sci U S A. 103(46):17366-71. 2006
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| 10 | CASP12
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| Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms.
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| Saleh M, Vaillancourt JP, Graham RK, Huyck M, Srinivasula SM, Alnemri ES, Steinberg MH, Nolan V, Baldwin CT, Hotchkiss RS, Buchman TG, Zehnbauer BA, Hayden MR, Farrer LA, Roy S, Nicholson DW.
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| Nature 429(6987):75-9. 2004
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| 11 | CASP12
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| Na/Ca exchanger overexpression induces endoplasmic reticulum stress, caspase-12 release, and apoptosis.
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| Diaz-Horta O, Van Eylen F, Herchuelz A.
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| Ann N Y Acad Sci 1010:430-2. 2003
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| 12 | CASP12
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| Human caspase 12 has acquired deleterious mutations.
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| Fischer H, Koenig U, Eckhart L, Tschachler E.
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| Biochem Biophys Res Commun 293(2):722-6. 2002
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| 13 | CASP12, HSPA5
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| Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78.
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| Rao RV, Peel A, Logvinova A, del Rio G, Hermel E, Yokota T, Goldsmith PC, Ellerby LM, Ellerby HM, Bredesen DE.
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| FEBS Lett. 514(2-3):122-8. 2002
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| 14 | CASP12
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| Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress.
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| Yoneda T, Imaizumi K, Oono K, Yui D, Gomi F, Katayama T, Tohyama M.
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| J Biol Chem. 276(17):13935-40. 2001
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| 15 | CASP12
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| Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta.
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| Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, Yuan J.
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| Nature 403(6765):98-103. 2000
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