Citations for
1CASK, TBR1
Calcium/calmodulin-dependent serine protein kinase (CASK), a protein implicated in mental retardation and autism-spectrum disorders, interacts with T-Brain-1 (TBR1) to control extinction of associative memory in male mice.
Huang TN, Hsueh YP.
J Psychiatry Neurosci 42(1):37-47. 2017
2CASK, DLG1
Scaffolding proteins DLG1 and CASK cooperate to maintain the nephron progenitor population during kidney development.
Ahn SY, Kim Y, Kim ST, Swat W, Miner JH.
J Am Soc Nephrol 24(7):1127-38. doi: 10.1681/ASN.2012111074. Epub 2013 May 9. 2013
3CASK, DLG1
CASK Regulates SAP97 Conformation and Its Interactions with AMPA and NMDA Receptors.
Lin EI, Jeyifous O, Green WN.
J Neurosci 33(29):12067-76. doi: 10.1523/JNEUROSCI.0816-13.2013. 2013
4CASK, PPFIA2, RIMS1
Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission.
Spangler SA, Schmitz SK, Kevenaar JT, de Graaff E, de Wit H, Demmers J, Toonen RF, Hoogenraad CC.
J Cell Biol 201(6):915-28. doi: 10.1083/jcb.201301011. 2013
5CASK, P2RX3
Calcium/calmodulin-dependent serine protein kinase (CASK) is a new intracellular modulator of P2X3 receptors.
Gnanasekaran A, Sundukova M, Hullugundi S, Birsa N, Bianchini G, Hsueh YP, Nistri A, Fabbretti E.
J Neurochem 126(1):102-12. doi: 10.1111/jnc.12272. Epub 2013 May 13. 2013
6CASK, FRMD7, NYS1A
A novel interaction between FRMD7 and CASK: evidence for a causal role in idiopathic infantile nystagmus.
Watkins RJ, Patil R, Goult BT, Thomas MG, Gottlob I, Shackleton S.
Hum Mol Genet 22(10):2105-18. doi: 10.1093/hmg/ddt060. Epub 2013 Feb 12. 2013
7CASK
Alternative Splicing of a Novel Inducible Exon Diversifies the CASK Guanylate Kinase Domain.
Dembowski JA, An P, Scoulos-Hanson M, Yeo G, Han J, Fu XD, Grabowski PJ.
J Nucleic Acids 2012:816237. Epub 2012 Sep 12. 2012
8CASK, MICPCH
CASK aberrations in male patients with Ohtahara syndrome and cerebellar hypoplasia.
Saitsu H, Kato M, Osaka H, Moriyama N, Horita H, Nishiyama K, Yoneda Y, Kondo Y, Tsurusaki Y, Doi H, Miyake N, Hayasaka K, Matsumoto N.
Epilepsia 53(8):1441-9. doi: 10.1111/j.1528-1167.2012.03548.x. Epub 2012 Jun 18. 2012
9CASK, GJA1
CASK (LIN2) interacts with Cx43 in wounded skin and their coexpression affects cell migration.
Márquez-Rosado L, Singh D, Rincón-Arano H, Solan JL, Lampe PD.
J Cell Sci 125(Pt 3):695-702. doi: 10.1242/jcs.084400. 2012
10CASK, MCPCH
Novel intragenic duplications and mutations of CASK in patients with mental retardation and microcephaly with pontine and cerebellar hypoplasia (MICPCH).
Hayashi S, Okamoto N, Chinen Y, Takanashi J, Makita Y, Hata A, Imoto I, Inazawa J.
Hum Genet 131(1):99-110. doi: 10.1007/s00439-011-1047-0. Epub 2011 Jul 7. 2012
11ATP2B4, CASK, F11R
CASK interacts with PMCA4b and JAM-A on the mouse sperm flagellum to regulate Ca2+ homeostasis and motility.
Aravindan RG, Fomin VP, Naik UP, Modelski MJ, Naik MU, Galileo DS, Duncan RL, Martin-Deleon PA.
J Cell Physiol 227(8):3138-50. doi: 10.1002/jcp.24000. 2012
12CASK, MICPCH
Phenotypic spectrum associated with CASK loss-of-function mutations.
Moog U, Kutsche K, Kortüm F, Chilian B, Bierhals T, Apeshiotis N, Balg S, Chassaing N, Coubes C, Das S, Engels H, Van Esch H, Grasshoff U, Heise M, Isidor B, Jarvis J, Koehler U, Martin T, Oehl-Jaschkowitz B, Ortibus E, Pilz DT, Prabhakar P, Rappold G, Rau I, Rettenberger G, Schlüter G, Scott RH, Shoukier M, Wohlleber E, Zirn B, Dobyns WB, Uyanik G.
J Med Genet 48(11):741-51. doi: 10.1136/jmedgenet-2011-100218. Epub 2011 Sep 27. 2011
13CASK, CASKIN1
Tandem SAM domain structure of human Caskin1: a presynaptic, self-assembling scaffold for CASK.
Stafford RL, Hinde E, Knight MJ, Pennella MA, Ear J, Digman MA, Gratton E, Bowie JU.
Structure 19(12):1826-36. doi: 10.1016/j.str.2011.09.018. 2011
14CASK
Pre and postsynaptic roles for Drosophila CASK.
Chen K, Featherstone DE.
Mol Cell Neurosci 48(2):171-82. doi: 10.1016/j.mcn.2011.07.009. Epub 2011 Jul 28. 2011
15APBA1, CASK, CASKIN1
The molecular basis of the Caskin1 and Mint1 interaction with CASK.
Stafford RL, Ear J, Knight MJ, Bowie JU.
J Mol Biol 412(1):3-13. doi: 10.1016/j.jmb.2011.07.005. Epub 2011 Jul 12. 2011
16CASK, NF1, SDC2
Characterisation of the interaction between syndecan-2, neurofibromin and CASK: dependence of interaction on syndecan dimerization.
Volta M, Calza S, Roberts AM, Roberts RG.
Biochem Biophys Res Commun 391(2):1216-21. Epub 2009 Dec 16.PMID: 20006588 2010
17CASK, MICPCH
CASK mutations are frequent in males and cause X-linked nystagmus and variable XLMR phenotypes.
Hackett A, Tarpey PS, Licata A, Cox J, Whibley A, Boyle J, Rogers C, Grigg J, Partington M, Stevenson RE, Tolmie J, Yates JR, Turner G, Wilson M, Futreal AP, Corbett M, Shaw M, Gecz J, Raymond FL, Stratton MR, Schwartz CE, Abidi FE.
Eur J Hum Genet 18(5):544-52. Epub 2009 Dec 23. Erratum in: Eur J Hum Genet. 2010 May;18(5):552. PMID: 20029458 2010
18CASK, FGS4
A missense mutation in CASK causes FG syndrome in an Italian family.
Piluso G, D'Amico F, Saccone V, Bismuto E, Rotundo IL, Di Domenico M, Aurino S, Schwartz CE, Neri G, Nigro V.
Am J Hum Genet 84(2):162-77. Epub 2009 Feb 5. 2009
19AP1S2, BRWD3, CASK, CUL4B, MRX65, MRX96, SLC9A6, SYP, UPF3B, ZDHHC9, ZNF711
A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation.
Tarpey PS, Smith R, Pleasance E, Whibley A, Edkins S, Hardy C, O'Meara S, Latimer C, Dicks E, Menzies A, Stephens P, Blow M, Greenman C, Xue Y, Tyler-Smith C, Thompson D, Gray K, Andrews J, Barthorpe S, Buck G, Cole J, Dunmore R, Jones D, Maddison M, Mironenko T, Turner R, Turrell K, Varian J, West S, Widaa S, Wray P, Teague J, Butler A, Jenkinson A, Jia M, Richardson D, Shepherd R, Wooster R, Tejada MI, Martinez F, Carvill G, Goliath R, de Brouwer AP, van Bokhoven H, Van Esch H, Chelly J, Raynaud M, Ropers HH, Abidi FE, Srivastava AK, Cox J, Luo Y, Mallya U, Moon J, Parnau J, Mohammed S, Tolmie JL, Shoubridge C, Corbett M, Gardner A, Haan E, Rujirabanjerd S, Shaw M, Vandeleur L, Fullston T, Easton DF, Boyle J, Partington M, Hackett A, Field M, Skinner C, Stevenson RE, Bobrow M, Turner G, Schwartz CE, Gecz J, Raymond FL, Futreal PA, Stratton MR.
Nat Genet 41(5):535-43. Epub 2009 Apr 19. 2009
20CASK, GRIN2B, TAF9
CASK point mutation regulates protein-protein interactions and NR2b promoter activity.
Huang TN, Hsueh YP.
Biochem Biophys Res Commun 382(1):219-22. Epub 2009 Mar 9. 2009
21CASK, GPR34, GPR82, MICPCH, RELN, TBR1
An X-linked microcephaly syndrome caused by disruptions of CASK implicates the CASK-TBR1-RELN pathway in human brain development.
Bailey KA, Aldinger KA.
Clin Genet 75(5):424-5. No abstract available. 2009
22CASK, CDKN1A, TCF3
Human calcium/calmodulin-dependent serine protein kinase regulates the expression of p21 via the E2A transcription factor.
Sun R, Su Y, Zhao X, Qi J, Luo X, Yang Z, Yao Y, Luo X, Xia Z.
Biochem J 419(2):457-66. Erratum in: Biochem J. 2009 Jun 15;420(3):493. PMID: 19125693 2009
23CASK, DLG1
SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway.
Jeyifous O, Waites CL, Specht CG, Fujisawa S, Schubert M, Lin EI, Marshall J, Aoki C, de Silva T, Montgomery JM, Garner CC, Green WN.
Nat Neurosci. 12(8):1011-9. 2009
24CASK, DLG1, LIN7C
CASK deletion in intestinal epithelia causes mislocalization of LIN7C and the DLG1/Scrib polarity complex without affecting cell polarity.
Lozovatsky L, Abayasekara N, Piawah S, Walther Z.
Mol Biol Cell 20(21):4489-99. Epub 2009 Sep 2.PMID: 19726564 2009
25CASK
The CASK gene harbored in a deletion detected by array-CGH as a potential candidate for a gene causative of X-linked dominant mental retardation.
Hayashi S, Mizuno S, Migita O, Okuyama T, Makita Y, Hata A, Imoto I, Inazawa J.
Am J Med Genet A 146A(16):2145-51. 2008
26CASK, MICPCH, TBR1
Mutations of CASK cause an X-linked brain malformation phenotype with microcephaly and hypoplasia of the brainstem and cerebellum.
Najm J, Horn D, Wimplinger I, Golden JA, Chizhikov VV, Sudi J, Christian SL, Ullmann R, Kuechler A, Haas CA, Flubacher A, Charnas LR, Uyanik G, Frank U, Klopocki E, Dobyns WB, Kutsche K.
Nat Genet at Genet. 2008 Aug 10. [Epub ahead of print] 2008
27CASK
CASK Functions as a Mg2+-independent neurexin kinase.
Mukherjee K, Sharma M, Urlaub H, Bourenkov GP, Jahn R, Südhof TC, Wahl MC.
Cell 133(2):328-39. 2008
28CASK
SUMOylation of the MAGUK protein CASK regulates dendritic spinogenesis.
Chao HW, Hong CJ, Huang TN, Lin YL, Hsueh YP.
J Cell Biol 182(1):141-55. Epub 2008 Jul 7. 2008
29CASK
Deletion of CASK in mice is lethal and impairs synaptic function.
Atasoy D, Schoch S, Ho A, Nadasy KA, Liu X, Zhang W, Mukherjee K, Nosyreva ED, Fernandez-Chacon R, Missler M, Kavalali ET, Südhof TC.
Proc Natl Acad Sci U S A 104(7):2525-30. Epub 2007 Feb 7. 2007
30CASK
CASK associates with glutamate receptor interacting protein and signaling molecules.
Hong CJ, Hsueh YP.
Biochem Biophys Res Commun 351(3):771-6. Epub 2006 Oct 30. 2006
31CASK
CASK inhibits ECV304 cell growth and interacts with Id1.
Qi J, Su Y, Sun R, Zhang F, Luo X, Yang Z, Luo X.
Biochem Biophys Res Commun 328(2):517-21. 2005
32CASK, PPFIA2
Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex.
Olsen O, Moore KA, Fukata M, Kazuta T, Trinidad JC, Kauer FW, Streuli M, Misawa H, Burlingame AL, Nicoll RA, Bredt DS.
J Cell Biol 170(7):1127-34. 2005
33CASK, TSPYL2
Transcriptional modification by a CASK-interacting nucleosome assembly protein.
Wang GS, Hong CJ, Yen TY, Huang HY, Ou Y, Huang TN, Jung WG, Kuo TY, Sheng M, Wang TF, Hsueh YP.
Neuron 42(1):113-28. Erratum in: Neuron. 2004 Aug 5;43(3):437. 2004
34CASK, TBR1
Identification of Tbr-1/CASK complex target genes in neurons.
Wang TF, Ding CN, Wang GS, Luo SC, Lin YL, Ruan Y, Hevner R, Rubenstein JL, Hsueh YP.
J Neurochem 91(6):1483-92. 2004
35CASK
A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels.
Leonoudakis D, Conti LR, Radeke CM, McGuire LM, Vandenberg CA.
J Biol Chem. 279(18):19051-63. 2004
36CASK, CASKIN2
Carom: a novel membrane-associated guanylate kinase-interacting protein with two SH3 domains.
Ohno H, Hirabayashi S, Kansaku A, Yao I, Tajima M, Nishimura W, Ohnishi H, Mashima H, Fujita T, Omata M, Hata Y.
Oncogene 22(52):8422-31. 2003
37CASK
Interaction of the plasma membrane Ca2+ pump 4b/CI with the Ca2+/calmodulin-dependent membrane-associated kinase CASK.
Schuh K, Uldrijan S, Gambaryan S, Roethlein N, Neyses L.
J Biol Chem. 278(11):9778-83. 2003
38CASK, WHRN
CIP98, a novel PDZ domain protein, is expressed in the central nervous system and interacts with calmodulin-dependent serine kinase.
Yap CC, Liang F, Yamazaki Y, Muto Y, Kishida H, Hayashida T, Hashikawa T, Yano R.
J Neurochem. 85(1):123-34. 2003
39CASK, LIN7A
Coordinated folding and association of the LIN-2, -7 (L27) domain. An obligate heterodimerization involved in assembly of signaling and cell polarity complexes.
Harris BZ, Venkatasubrahmanyam S, Lim WA.
J Biol Chem 277(38):34902-8. 2002
40CASK, CASKIN1, CASKP, RELN
CASK and its target gene Reelin were co-upregulated in human esophageal carcinoma.
Wang Q, Lu J, Yang C, Wang X, Cheng L, Hu G, Sun Y, Zhang X, Wu M, Liu Z.
Cancer Lett 179(1):71-7. 2002
41CASK, CASKIN1, CASKIN2
CASK participates in alternative tripartite complexes in which Mint 1 competes for binding with caskin 1, a novel CASK-binding protein.
Tabuchi K, Biederer T, Butz S, Sudhof TC.
J Neurosci 22(11):4264-73. 2002
42CASK, PRKN
Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain.
Fallon L, Moreau F, Croft BG, Labib N, Gu WJ, Fon EA.
J Biol Chem 277(1):486-91. Epub 2001 Oct 25. 2002
43CASK, CNTNAP3, CNTNAP4
Caspr3 and caspr4, two novel members of the caspr family are expressed in the nervous system and interact with PDZ domains.
Spiegel I, Salomon D, Erne B, Schaeren-Wiemers N, Peles E.
Mol Cell Neurosci 20(2):283-97. 2002
44CASK, NRXN1
CASK and protein 4.1 support F-actin nucleation on neurexins.
Biederer T, Sudhof TC.
J Biol Chem 276(51):47869-76. Epub 2001 Oct 16. 2001
45CASK
Association of junctional adhesion molecule with calcium/calmodulin-dependent serine protein kinase (CASK/LIN-2) in human epithelial caco-2 cells.
Martinez-Estrada OM, Villa A, Breviario F, Orsenigo F, Dejana E, Bazzoni G.
J Biol Chem. 276(12):9291-6. 2001
46CASK
The scaffolding protein CASK mediates the interaction between rabphilin3a and beta-neurexins.
Zhang Y, Luan Z, Liu A, Hu G.
FEBS Lett. 497(2-3):99-102. 2001
47CASK, CSNB1A, USP9X
Development of a 1.4-Mb BAC/PAC contig and physical map within the critical region for complete X-linked congenital stationary night blindness in xp11.4.
Sparkes RL, Summer CG, Boycott KM, Zahorchak RJ, Bech-Hansen NT.
Genomics 68(1):97-100. 2000
48CASK
Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2.
Hsueh YP, Wang TF, Yang FC, Sheng M.
Nature 404(6775):298-302. 2000
49APBA1, CASK, LIN7A
Mapping and expression analysis of the human CASK gene.
Stevenson D, Laverty HG, Wenwieser S, Douglas M, Wilson JB.
Mamm Genome 11(10):934-7. No abstract available. 2000
50CASK
hCASK and hDlg associate in epithelia, and their src homology 3 and guanylate kinase domains participate in both intramolecular and intermolecular interactions.
Nix SL, Chishti AH, Anderson JM, Walther Z.
J Biol Chem. 275(52):41192-200. 2000
51CASK
Association of neuronal calcium channels with modular adaptor proteins.
Maximov A, Südhof TC, Bezprozvanny I.
J Biol Chem. 274(35):24453-6. 1999
52CASK
Regulated expression and subcellular localization of syndecan heparan sulfate proteoglycans and the syndecan-binding protein CASK/LIN-2 during rat brain development.
Hsueh YP, Sheng M.
J Neurosci. 19(17):7415-25. 1999
53CASK
The location of human CASK at Xp11.4 identifies this gene as a candidate for X-linked optic atrophy.
Dimitratos SD, et al.
Genomics 51 : 308-309. 1998
54CASK
Human CASK/LIN-2 binds syndecan-2 and protein 4.1 and localizes to the basolateral membrane of epithelial cells.
Cohen AR, Woods DF, Marfatia SM, Walther Z, Chishti AH, Anderson JM, Wood DF.
J Cell Biol 142(1):129-38. 1998
55CASK
Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting.
Borg JP, Straight SW, Kaech SM, de Taddéo-Borg M, Kroon DE, Karnak D, Turner RS, Kim SK, Margolis B.
J Biol Chem. 273(48):31633-6 1998
56CASK
Camguk, Lin-2, and CASK : novel membrane-associated guanylate kinase homologs that also contain CaM kinase domains.
Dimitratos SD, et al.
Mech Dev 63 : 127-130. 1997
57ATXN2, BHLHE22, CASK, CELF3, CNPY3, EP400, FOXP2, JPH3, KMT2D, MAGI1, MAML3, MED12, MED15, NUMBL, PAXIP1, TNRC15, TNRC17, TNRC18, TNRC6A, TOX3, ZNF384
cDNAs with long CAG trinucleotide repeats from human brain.
Margolis RL, Abraham MR, Gatchell SB, Li SH, Kidwai AS, Breschel TS, Stine OC, Callahan C, McInnis MG, Ross CA.
Hum Genet 100(1):114-22. 1997
58CASK
CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins.
Hata Y, Butz S, Südhof TC.
J Neurosci. 16(8):2488-94. 1996