Citations for
1CARD14, PRP
Altered replication stress response due to CARD14 mutations promotes recombination-induced revertant mosaicism
Miyauchi T, Suzuki S, Takeda M, Peh JT, Aiba M, Natsuga K, Fujita Y, Takeichi T, Sakamoto T, Akiyama M, Shimizu H, Nomura T.
Am J Hum Genet. Jun 3;108(6):1026-1039. doi: 10.1016/j.ajhg.2021.04.021. Epub 2021 May 17. 2021
2BCL10, CARD14, MALT1
Regulation and dysregulation of CARD14 signalling and its physiological consequences in inflammatory skin disease
Mellett M.
Cell Immunol. Aug;354:104147. doi: 10.1016/j.cellimm.2020.104147. Epub 2020 Jun 13 2020
3CARD14, UBAC1
UBAC1/KPC2 Regulates TLR3 Signaling in Human Keratinocytes through Functional Interaction with the CARD14/CARMA2sh-TANK Complex
Mazzone P, Congestrì M, Scudiero I, Polvere I, Voccola S, Zerillo L, Telesio G, Vito P, Stilo R, Zotti T.
Int J Mol Sci. Dec 9;21(24):9365. doi: 10.3390/ijms21249365. 2020
4CARD14
Whole exome sequencing approach to childhood onset familial erythrodermic psoriasis unravels a novel mutation of CARD14 requiring unusual high doses of ustekinumab
Signa S, Campione E, Rusmini M, Chiesa S, Grossi A, Omenetti A, Caorsi R, Viglizzo GM, Galluzzo M, Bianchi L, Talamonti M, Orlandi A, Martini A, Ceccherini I, Gattorno M.
Pediatr Rheumatol Online J. Jul 8;17(1):38. doi: 10.1186/s12969-019-0336-3. 2019
5CARD14
. Loss-of-function mutations in caspase recruitment domain-containing protein 14 (CARD14) are associated with a severe variant of atopic dermatitis
Peled A, Sarig O, Sun G, Samuelov L, Ma CA, Zhang Y, Dimaggio T, Nelson CG, Stone KD, Freeman AF, Malki L, Vidal LS, Chamarthy LM, Briskin V, Mohamad J, Pavlovsky M, Walter JE, Milner JD, Sprecher E
J Allergy Clin Immunol. Jan;143(1):173-181.e10. doi: 10.1016/j.jaci.2018.09.002. Epub 2018 Sep 21. 2019
6CARD14, PRP
CARD14-associated papulosquamous eruption: A spectrum including features of psoriasis and pityriasis rubra pilaris.
Craiglow BG, Boyden LM, Hu R, Virtanen M, Su J, Rodriguez G, McCarthy C, Luna P, Larralde M, Humphrey S, Holland KE, Hogeling M, Hidalgo-Matlock B, Ferrari B, Fernandez-Faith E, Drolet B, Cordoro KM, Bowcock AM, Antaya RJ, Ashack K, Ashack RJ, Lifton RP, Milstone LM, Paller AS, Choate KA.
J Am Acad Dermatol. Sep;79(3):487-494. doi: 10.1016/j.jaad.2018.02.034. Epub 2018 Mar 1. 2018
7CARD14
CARD14/CARMA2 Signaling and its Role in Inflammatory Skin Disorders. Front Immunol.
Zotti T, Polvere I, Voccola S, Vito P, Stilo R.
Front Immunol. Sep 26;9:2167. doi: 10.3389/fimmu.2018.02167. 2018
8CARD14, RNF7
The E3 Ubiquitin Ligase RNF7 Negatively Regulates CARD14/CARMA2sh Signaling.
Telesio G, Scudiero I, Pizzulo M, Mazzone P, Zotti T, Voccola S, Polvere I, Vito P, Stilo R.
Int J Mol Sci. Dec 1;18(12):2581. doi: 10.3390/ijms18122581 2017
9BCL10, CARD14, MALT1
CARD14-Mediated Activation of Paracaspase MALT1 in Keratinocytes: Implications for Psoriasis
Van Nuffel E, Schmitt A, Afonina IS, Schulze-Osthoff K, Beyaert R, Hailfinger S.
J Invest Dermatol. Mar;137(3):569-575. doi: 10.1016/j.jid.2016.09.031. Epub 2016 Dec 8. 2017
10CARD14, PRP
Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation
Howes A, O'Sullivan PA, Breyer F, Ghose A, Cao L, Krappmann D, Bowcock AM, Ley SC.
Biochem J. Jun 15;473(12):1759-68. doi: 10.1042/BCJ20160270. Epub 2016 Apr 12. 2016
11CARD14, MALT1
The paracaspase MALT1 mediates CARD14-induced signaling in keratinocytes.
Afonina IS, Van Nuffel E, Baudelet G, Driege Y, Kreike M, Staal J, Beyaert R.
EMBO Rep. Jun;17(6):914-27. doi: 10.15252/embr.201642109. Epub 2016 Apr 25. 2016
12CARD14, PRP
CARD14 Glu138 mutation in familial pityriasis rubra pilaris does not warrant differentiation from familial psoriasis.
Inoue N, Dainichi T, Fujisawa A, Nakano H, Sawamura D, Kabashima K.
J Dermatol. Feb;43(2):187-9. doi: 10.1111/1346-8138.13008. Epub 2015 Jul 1. 2016
13CARD14
Rare and Common Variants in CARD14, Encoding an Epidermal Regulator of NF-kappaB, in Psoriasis.
Jordan CT, Cao L, Roberson ED, Duan S, Helms CA, Nair RP, Duffin KC, Stuart PE, Goldgar D, Hayashi G, Olfson EH, Feng BJ, Pullinger CR, Kane JP, Wise CA, Goldbach-Mansky R, Lowes MA, Peddle L, Chandran V, Liao W, Rahman P, Krueger GG, Gladman D, Elder JT, Menter A, Bowcock AM.
Am J Hum Genet 90(5):796-808. Epub 2012 Apr 19. 2012
14CARD14, PSORS2
PSORS2 Is Due to Mutations in CARD14.
Jordan CT, Cao L, Roberson ED, Pierson KC, Yang CF, Joyce CE, Ryan C, Duan S, Helms CA, Liu Y, Chen Y, McBride AA, Hwu WL, Wu JY, Chen YT, Menter A, Goldbach-Mansky R, Lowes MA, Bowcock AM.
Am J Hum Genet 90(5):784-95. Epub 2012 Apr 19. 2012
15CARD14, PRP
Familial Pityriasis Rubra Pilaris Is Caused by Mutations in CARD14.
Fuchs-Telem D, Sarig O, van Steensel MA, Isakov O, Israeli S, Nousbeck J, Richard K, Winnepenninckx V, Vernooij M, Shomron N, Uitto J, Fleckman P, Richard G, Sprecher E.
Am J Hum Genet 91(1):163-70. Epub 2012 Jun 14. 2012
16CARD14
Alternative splicing of CARMA2/CARD14 transcripts generates protein variants with differential effect on NF-κB activation and endoplasmic reticulum stress-induced cell death.
Scudiero I, Zotti T, Ferravante A, Vessichelli M, Vito P, Stilo R.
J Cell Physiol 226(12):3121-31. doi: 10.1002/jcp.22667. 2011
17CARD14
NF-κB signaling pathways regulated by CARMA family of scaffold proteins.
Blonska M, Lin X.
Cell Res 21(1):55-70. Epub 2010 Dec 28. Review. 2011
18CARD14
Structure and expression pattern of teleost caspase recruitment domain (CARD) containing proteins that are potentially involved in NF-kappaB signalling.
Chang MX, Chen WQ, Nie P.
Dev Comp Immunol 34(1):1-13. Epub 2009 Aug 28. 2010
19CARD11, CARD14
CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B.
Bertin J, Wang L, Guo Y, Jacobson MD, Poyet JL, Srinivasula SM, Merriam S, DiStefano PS, Alnemri ES.
J Biol Chem 276(15):11877-82. 2001
20CARD10, CARD11, CARD14, CARD9
Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa B.
Wang L, Guo Y, Huang WJ, Ke X, Poyet JL, Manji GA, Merriam S, Glucksmann MA, DiStefano PS, Alnemri ES, Bertin J.
J Biol Chem 276(24):21405-9. 2001
21BCL10, CARD10, CARD11, NLRC4, CARD14, NOD1, NOD2, CARD9, RIPK2
Caspase recruitment domain (CARD)-dependent cytoplasmic filaments mediate bcl10-induced NF-kappaB activation.
Guiet C, Vito P.
J Cell Biol 148(6):1131-40. 2000