Citations for
Homozygous calreticulin mutations in patients with myelofibrosis lead to acquired myeloperoxidase deficiency.
Theocharides AP, Lundberg P, Lakkaraju AK, Lysenko V, Myburgh R, Aguzzi A, Skoda RC, Manz MG.
Blood 127(25):3253-9. doi: 10.1182/blood-2016-02-696310. Epub 2016 Mar 24. 2016
Purification and characterization of a soluble calnexin from human placenta.
Olsen DT, Peng L, Træholt SD, Duus K, Højrup P, Houen G.
Protein Expr Purif 92(1):105-11. doi: 10.1016/j.pep.2013.09.006. Epub 2013 Sep 19. 2013
The polypeptide binding conformation of calreticulin facilitates its cell-surface expression under conditions of endoplasmic reticulum stress.
Jeffery E, Peters LR, Raghavan M.
J Biol Chem 286(4):2402-15. Epub 2010 Nov 12. 2011
Calreticulin is crucial for calcium homeostasis mediated adaptation and survival of thick ascending limb of Henle's loop cells under osmotic stress.
Bibi A, Agarwal NK, Dihazi GH, Eltoweissy M, Van Nguyen P, Mueller GA, Dihazi H.
Int J Biochem Cell Biol. 43(8):1187-97. 2011
Atg8-family interacting motif crucial for selective autophagy.
Noda NN, Ohsumi Y, Inagaki F.
FEBS Lett 584(7):1379-85. Epub 2010 Jan 17. Review.PMID: 20083108 2010
Calreticulin controls the rate of assembly of CD1d molecules in the endoplasmic reticulum.
Zhu Y, Zhang W, Veerapen N, Besra G, Cresswell P.
J Biol Chem 285(49):38283-92. Epub 2010 Sep 22. 2010
Structural framework of the GABARAP-calreticulin interface--implications for substrate binding to endoplasmic reticulum chaperones.
Thielmann Y, Weiergräber OH, Mohrlüder J, Willbold D.
FEBS J 276(4):1140-52. Epub 2009 Jan 16.PMID: 19154346 2009
Calreticulin promotes cell motility and enhances resistance to anoikis through STAT3-CTTN-Akt pathway in esophageal squamous cell carcinoma.
Du XL, Yang H, Liu SG, Luo ML, Hao JJ, Zhang Y, Lin DC, Xu X, Cai Y, Zhan QM, Wang MR.
Oncogene 28(42):3714-22. Epub 2009 Aug 17.PMID: 19684620 2009
Calreticulin enhances B2 bradykinin receptor maturation and heterodimerization.
Abd Alla J, Reeck K, Langer A, Streichert T, Quitterer U.
Biochem Biophys Res Commun 387(1):186-90. Epub 2009 Jul 4.PMID: 19580784 2009
Suppressive roles of calreticulin in prostate cancer growth and metastasis.
Alur M, Nguyen MM, Eggener SE, Jiang F, Dadras SS, Stern J, Kimm S, Roehl K, Kozlowski J, Pins M, Michalak M, Dhir R, Wang Z.
Am J Pathol 175(2):882-90. Epub 2009 Jul 16.PMID: 19608864 2009
Identification of calreticulin as a prognosis marker and angiogenic regulator in human gastric cancer.
Chen CN, Chang CC, Su TE, Hsu WM, Jeng YM, Ho MC, Hsieh FJ, Lee PH, Kuo ML, Lee H, Chang KJ.
Ann Surg Oncol 16(2):524-33. Epub 2008 Dec 3.PMID: 19050968 2009
Calreticulin in human pregnancy and pre-eclampsia.
Gu VY, Wong MH, Stevenson JL, Crawford KE, Brennecke SP, Gude NM.
Mol Hum Reprod 14(5):309-15. Epub 2008 Apr 16.PMID: 18417548 2008
Calreticulin negatively regulates the cell surface expression of cystic fibrosis transmembrane conductance regulator.
Harada K, Okiyoneda T, Hashimoto Y, Ueno K, Nakamura K, Yamahira K, Sugahara T, Shuto T, Wada I, Suico MA, Kai H.
J Biol Chem 281(18):12841-8. Epub 2006 Mar 9. 2006
14CD69, CALR
Human CD69 associates with an N-terminal fragment of calreticulin at the cell surface.
Vance BA, Harley PH, Backlund PS, Ward Y, Phelps TL, Gress RE.
Arch Biochem Biophys 438(1):11-20. 2005
Overexpression of calreticulin sensitizes SERCA2a to oxidative stress.
Ihara Y, Kageyama K, Kondo T.
Biochem Biophys Res Commun 329(4):1343-9. 2005
Calreticulin, a Ca2+-binding chaperone of the endoplasmic reticulum.
Gelebart P, Opas M, Michalak M.
Int J Biochem Cell Biol. 37(2):260-6. 2005
A polypeptide binding conformation of calreticulin is induced by heat shock, calcium depletion, or by deletion of the C-terminal acidic region.
Rizvi SM, Mancino L, Thammavongsa V, Cantley RL, Raghavan M
Mol Cell. 15(6):913-23. 2004
The low-density lipoprotein receptor-related protein associates with calnexin, calreticulin, and protein disulfide isomerase in receptor-associated-protein-deficient fibroblasts.
Orlando RA.
Exp Cell Res. 294(1):244-53. 2004
Competition of CUGBP1 and calreticulin for the regulation of p21 translation determines cell fate.
Iakova P, Wang GL, Timchenko L, Michalak M, Pereira-Smith OM, Smith JR, Timchenko NA.
EMBO J. 23(2):406-17. 2004
Calreticulin promotes folding/dimerization of human lipoprotein lipase expressed in insect cells (sf21).
Zhang L, Wu G, Tate CG, Lookene A, Olivecrona G.
J Biol Chem. 278(31):29344-51. 2003
Localization of the lectin, ERp57 binding, and polypeptide binding sites of calnexin and calreticulin.
Leach MR, Cohen-Doyle MF, Thomas DY, Williams DB.
J Biol Chem 277(33):29686-97. Epub 2002 Jun 06. 2002
Calnexin, calreticulin, and ERp57 cooperate in disulfide bond formation in human CD1d heavy chain.
Kang SJ, Cresswell P.
J Biol Chem 277(47):44838-44. Epub 2002 Sep 17. 2002
Calreticulin in cardiac development and pathology.
Michalak M, Lynch J, Groenendyk J, Guo L, Robert Parker JM, Opas M.
Biochim Biophys Acta 1600(1-2):32-7. Review. 2002
Association of the thyrotropin receptor with calnexin, calreticulin and BiP. Efects on the maturation of the receptor.
Siffroi-Fernandez S, Giraud A, Lanet J, Franc JL.
Eur J Biochem. 269(20):4930-7. 2002
The anti-adhesive activity of thrombospondin is mediated by the N-terminal domain of cell surface calreticulin.
Goicoechea S, Pallero MA, Eggleton P, Michalak M, Murphy-Ullrich JE.
J Biol Chem. 277(40):37219-28. 2002
Calreticulin interacts with C/EBPalpha and C/EBPbeta mRNAs and represses translation of C/EBP proteins.
Timchenko LT, Iakova P, Welm AL, Cai ZJ, Timchenko NA.
Mol Cell Biol. 22(20):7242-57. 2002
27CALR, NKX2-5, NR2F1
COUP-TF1 antagonizes Nkx2.5-mediated activation of the calreticulin gene during cardiac development.
Guo L, Lynch J, Nakamura K, Fliegel L, Kasahara H, Izumo S, Komuro I, Agellon LB, Michalak M.
J Biol Chem 276(4):2797-801. 2001
Calreticulin functions as a molecular chaperone for the beta-amyloid precursor protein.
Johnson RJ, Xiao G, Shanmugaratnam J, Fine RE.
Neurobiol Aging. 22(3):387-95. 2001
The measles virus (MV) glycoproteins interact with cellular chaperones in the endoplasmic reticulum and MV infection upregulates chaperone expression.
Bolt G.
Arch Virol. 146(11):2055-68. 2001
Calreticulin Is a receptor for nuclear export.
Holaska JM, Black BE, Love DC, Hanover JA, Leszyk J, Paschal BM.
J Cell Biol. 152(1):127-40. 2001
Functional relationship between calreticulin, calnexin, and the endoplasmic reticulum luminal domain of calnexin.
Danilczyk UG, Cohen-Doyle MF, Williams DB.
J Biol Chem 275(17):13089-97. 2000
Calreticulin: one protein, one gene, many functions.
Michalak M, Corbett EF, Mesaeli N, Nakamura K, Opas M.
Biochem J 344 Pt 2:281-92. Review. 1999
Interaction of newly synthesized apolipoprotein B with calnexin and calreticulin requires glucose trimming in the endoplasmic reticulum.
Tatu U, Helenius A.
Biosci Rep. 19(3):189-96. 1999
Regulation of fibrillin carboxy-terminal furin processing by N-glycosylation, and association of amino- and carboxy-terminal sequences.
Ashworth JL, Kelly V, Rock MJ, Shuttleworth CA, Kielty CM.
J Cell Sci. 112 ( Pt 22):4163-71. 1999
Calreticulin enhances the transcriptional activity of thyroid transcription factor-1 by binding to its homeodomain.
Perrone L, Tell G, Di Lauro R.
J Biol Chem. 274(8):4640-5. 1999
Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors.
Yoshida H, Haze K, Yanagi H, Yura T, Mori K.
J Biol Chem 273(50):33741-9. 1998
Differential interaction of coagulation factor VIII and factor V with protein chaperones calnexin and calreticulin.
Pipe SW, Morris JA, Shah J, Kaufman RJ.
J Biol Chem. 273(14):8537-44. 1998
Interaction between a Ca2+-binding protein calreticulin and perforin, a component of the cytotoxic T-cell granules.
Andrin C, Pinkoski MJ, Burns K, Atkinson EA, Krahenbuhl O, Hudig D, Fraser SA, Winkler U, Tschopp J, Opas M, Bleackley RC, Michalak M.
Biochemistry. 37(29):10386-94. 1998
Calnexin and calreticulin bind to enzymically active tissue-type plasminogen activator during biosynthesis and are not required for folding to the native conformation.
Allen S, Bulleid NJ.
Biochem J. 328 ( Pt 1):113-9. 1997
Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP.
Sadasivan B, et al.
Immunity 5 : 103-114. 1996
Calreticulin interacts with newly synthesized human immunodeficiency virus type 1 envelope glycoprotein, suggesting a chaperone function similar to that of calnexin.
Otteken A, Moss B.
J Biol Chem. 271(1):97-103. 1996
The glut 1 glucose transporter interacts with calnexin and calreticulin.
Oliver JD, Hresko RC, Mueckler M, High S.
J Biol Chem. 271(23):13691-6. 1996
Calreticulin binds hYRNA and the 52-kDa polypeptide component of the Ro/SS-A ribonucleoprotein autoantigen.
Cheng ST, Nguyen TQ, Yang YS, Capra JD, Sontheimer RD.
J Immunol. 156(11):4484-91. 1996
The mitogenic effects of the B beta chain of fibrinogen are mediated through cell surface calreticulin.
Gray AJ, Park PW, Broekelmann TJ, Laurent GJ, Reeves JT, Stenmark KR, Mecham RP.
J Biol Chem. 270(44):26602-6. 1995
Interaction of calreticulin with protein disulfide isomerase.
Baksh S, Burns K, Andrin C, Michalak M.
J Biol Chem. 270(52):31338-44. 1995
46CALR, RO60
Mapping of the human 60000 Mr Ro/SSA locus : the genes for three Ro/SSA autoantigens are located on separate chromosomes.
Frank MB, et al.
Immunogenetics 39 : 428-431. 1994
Inhibition of nuclear hormone receptor activity by calreticulin.
Dedhar S, Rennie PS, Shago M, Hagesteijn CY, Yang H, Filmus J, Hawley RG, Bruchovsky N, Cheng H, Matusik RJ, et al.
Nature 367(6462):480-3. 1994
Modulation of gene expression by calreticulin binding to the glucocorticoid receptor.
Burns K, Duggan B, Atkinson EA, Famulski KS, Nemer M, Bleackley RC, Michalak M.
Nature 367(6462):476-80. 1994
Calreticulin is released from activated neutrophils and binds to C1q and mannan-binding protein.
Eggleton P, Lieu TS, Zappi EG, Sastry K, Coburn J, Zaner KS, Sontheimer RD, Capra JD, Ghebrehiwet B, Tauber AI.
Clin Immunol Immunopathol. 72(3):405-9. 1994
Inhibition of nuclear hormone receptor activity by calreticulin.
Dedhar S, Rennie PS, Shago M, Hagesteijn CY, Yang H, Filmus J, Hawley RG, Bruchovsky N, Cheng H, Matusik RJ, et al.
Nature. 367(6462):480-3. 1994
In vitro interaction of a polypeptide homologous to human Ro/SS-A antigen (calreticulin) with a highly conserved amino acid sequence in the cytoplasmic domain of integrin alpha subunits.
Rojiani MV, Finlay BB, Gray V, Dedhar S.
Biochemistry. 30(41):9859-66. 1991
A human Ro/SS-A autoantigen is the homologue of calreticulin and is highly homologous with onchocercal RAL-1 antigen and an aplysia memory molecule.
McCauliffe DP, et al.
J Clin Invest 86 : 332-335. 1990
Molecular cloning, expression, and chromosome 19 localization of a human Ro/SS-A autoantigen.
McCauliffe DP, et al.
J Clin Invest 85 : 1379-1391. 1990
Ro/SS-A and the pathogenic significance of its antibodies.
McCauliffe DP, Lux FA, Lieu TS, Sanz I, Hanke J, Newkirk MM, Siciliano MJ, Sontheimer RD, Capra JD.
J Autoimmunity 2(4):375-81. 1989