| 1 | CALR, MPO
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| Homozygous calreticulin mutations in patients with myelofibrosis lead to acquired myeloperoxidase deficiency.
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| Theocharides AP, Lundberg P, Lakkaraju AK, Lysenko V, Myburgh R, Aguzzi A, Skoda RC, Manz MG.
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| Blood 127(25):3253-9. doi: 10.1182/blood-2016-02-696310. Epub 2016 Mar 24.
2016
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| 2 | CALR, CANX
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| Purification and characterization of a soluble calnexin from human placenta.
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| Olsen DT, Peng L, Træholt SD, Duus K, Højrup P, Houen G.
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| Protein Expr Purif 92(1):105-11. doi: 10.1016/j.pep.2013.09.006. Epub 2013 Sep 19.
2013
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| 3 | CALR
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| The polypeptide binding conformation of calreticulin facilitates its cell-surface expression under conditions of endoplasmic reticulum stress.
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| Jeffery E, Peters LR, Raghavan M.
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| J Biol Chem 286(4):2402-15. Epub 2010 Nov 12.
2011
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| 4 | CALR
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| Calreticulin is crucial for calcium homeostasis mediated adaptation and survival of thick ascending limb of Henle's loop cells under osmotic stress.
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| Bibi A, Agarwal NK, Dihazi GH, Eltoweissy M, Van Nguyen P, Mueller GA, Dihazi H.
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| Int J Biochem Cell Biol. 43(8):1187-97. 2011
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| 5 | BNIP3L, CALR, CLTC, GABARAP, NBR1, SQSTM1
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| Atg8-family interacting motif crucial for selective autophagy.
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| Noda NN, Ohsumi Y, Inagaki F.
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| FEBS Lett 584(7):1379-85. Epub 2010 Jan 17. Review.PMID: 20083108 2010
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| 6 | CALR, CD1D
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| Calreticulin controls the rate of assembly of CD1d molecules in the endoplasmic reticulum.
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| Zhu Y, Zhang W, Veerapen N, Besra G, Cresswell P.
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| J Biol Chem 285(49):38283-92. Epub 2010 Sep 22.
2010
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| 7 | CALR, GABARAP
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| Structural framework of the GABARAP-calreticulin interface--implications for substrate binding to endoplasmic reticulum chaperones.
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| Thielmann Y, Weiergräber OH, Mohrlüder J, Willbold D.
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| FEBS J 276(4):1140-52. Epub 2009 Jan 16.PMID: 19154346 2009
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| 8 | CALR
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| Calreticulin promotes cell motility and enhances resistance to anoikis through STAT3-CTTN-Akt pathway in esophageal squamous cell carcinoma.
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| Du XL, Yang H, Liu SG, Luo ML, Hao JJ, Zhang Y, Lin DC, Xu X, Cai Y, Zhan QM, Wang MR.
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| Oncogene 28(42):3714-22. Epub 2009 Aug 17.PMID: 19684620 2009
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| 9 | BDKRB2, CALR
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| Calreticulin enhances B2 bradykinin receptor maturation and heterodimerization.
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| Abd Alla J, Reeck K, Langer A, Streichert T, Quitterer U.
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| Biochem Biophys Res Commun 387(1):186-90. Epub 2009 Jul 4.PMID: 19580784 2009
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| 10 | CALR
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| Suppressive roles of calreticulin in prostate cancer growth and metastasis.
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| Alur M, Nguyen MM, Eggener SE, Jiang F, Dadras SS, Stern J, Kimm S, Roehl K, Kozlowski J, Pins M, Michalak M, Dhir R, Wang Z.
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| Am J Pathol 175(2):882-90. Epub 2009 Jul 16.PMID: 19608864 2009
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| 11 | CALR
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| Identification of calreticulin as a prognosis marker and angiogenic regulator in human gastric cancer.
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| Chen CN, Chang CC, Su TE, Hsu WM, Jeng YM, Ho MC, Hsieh FJ, Lee PH, Kuo ML, Lee H, Chang KJ.
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| Ann Surg Oncol 16(2):524-33. Epub 2008 Dec 3.PMID: 19050968 2009
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| 12 | CALR
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| Calreticulin in human pregnancy and pre-eclampsia.
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| Gu VY, Wong MH, Stevenson JL, Crawford KE, Brennecke SP, Gude NM.
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| Mol Hum Reprod 14(5):309-15. Epub 2008 Apr 16.PMID: 18417548 2008
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| 13 | CALR
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| Calreticulin negatively regulates the cell surface expression of cystic fibrosis transmembrane conductance regulator.
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| Harada K, Okiyoneda T, Hashimoto Y, Ueno K, Nakamura K, Yamahira K, Sugahara T, Shuto T, Wada I, Suico MA, Kai H.
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| J Biol Chem 281(18):12841-8. Epub 2006 Mar 9. 2006
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| 14 | CD69, CALR
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| Human CD69 associates with an N-terminal fragment of calreticulin at the cell surface.
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| Vance BA, Harley PH, Backlund PS, Ward Y, Phelps TL, Gress RE.
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| Arch Biochem Biophys 438(1):11-20. 2005
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| 15 | CALR, ATP2A2
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| Overexpression of calreticulin sensitizes SERCA2a to oxidative stress.
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| Ihara Y, Kageyama K, Kondo T.
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| Biochem Biophys Res Commun 329(4):1343-9. 2005
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| 16 | CALR
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| Calreticulin, a Ca2+-binding chaperone of the endoplasmic reticulum.
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| Gelebart P, Opas M, Michalak M.
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| Int J Biochem Cell Biol. 37(2):260-6. 2005
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| 17 | CALR
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| A polypeptide binding conformation of calreticulin is induced by heat shock, calcium depletion, or by deletion of the C-terminal acidic region.
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| Rizvi SM, Mancino L, Thammavongsa V, Cantley RL, Raghavan M
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| Mol Cell. 15(6):913-23. 2004
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| 18 | CALR
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| The low-density lipoprotein receptor-related protein associates with calnexin, calreticulin, and protein disulfide isomerase in receptor-associated-protein-deficient fibroblasts.
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| Orlando RA.
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| Exp Cell Res. 294(1):244-53. 2004
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| 19 | CALR
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| Competition of CUGBP1 and calreticulin for the regulation of p21 translation determines cell fate.
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| Iakova P, Wang GL, Timchenko L, Michalak M, Pereira-Smith OM, Smith JR, Timchenko NA.
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| EMBO J. 23(2):406-17. 2004
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| 20 | CALR
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| Calreticulin promotes folding/dimerization of human lipoprotein lipase expressed in insect cells (sf21).
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| Zhang L, Wu G, Tate CG, Lookene A, Olivecrona G.
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| J Biol Chem. 278(31):29344-51. 2003
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| 21 | CANX, CALR, PDIA3
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| Localization of the lectin, ERp57 binding, and polypeptide binding sites of calnexin and calreticulin.
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| Leach MR, Cohen-Doyle MF, Thomas DY, Williams DB.
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| J Biol Chem 277(33):29686-97. Epub 2002 Jun 06. 2002
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| 22 | CALR, CANX, PDIA3, CD1D
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| Calnexin, calreticulin, and ERp57 cooperate in disulfide bond formation in human CD1d heavy chain.
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| Kang SJ, Cresswell P.
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| J Biol Chem 277(47):44838-44. Epub 2002 Sep 17. 2002
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| 23 | CALR
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| Calreticulin in cardiac development and pathology.
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| Michalak M, Lynch J, Groenendyk J, Guo L, Robert Parker JM, Opas M.
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| Biochim Biophys Acta 1600(1-2):32-7. Review. 2002
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| 24 | CALR, HSPA5
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| Association of the thyrotropin receptor with calnexin, calreticulin and BiP. Efects on the maturation of the receptor.
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| Siffroi-Fernandez S, Giraud A, Lanet J, Franc JL.
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| Eur J Biochem. 269(20):4930-7. 2002
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| 25 | CALR
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| The anti-adhesive activity of thrombospondin is mediated by the N-terminal domain of cell surface calreticulin.
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| Goicoechea S, Pallero MA, Eggleton P, Michalak M, Murphy-Ullrich JE.
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| J Biol Chem. 277(40):37219-28. 2002
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| 26 | CALR
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| Calreticulin interacts with C/EBPalpha and C/EBPbeta mRNAs and represses translation of C/EBP proteins.
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| Timchenko LT, Iakova P, Welm AL, Cai ZJ, Timchenko NA.
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| Mol Cell Biol. 22(20):7242-57. 2002
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| 27 | CALR, NKX2-5, NR2F1
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| COUP-TF1 antagonizes Nkx2.5-mediated activation of the calreticulin gene during cardiac development.
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| Guo L, Lynch J, Nakamura K, Fliegel L, Kasahara H, Izumo S, Komuro I, Agellon LB, Michalak M.
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| J Biol Chem 276(4):2797-801. 2001
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| 28 | APP, CALR
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| Calreticulin functions as a molecular chaperone for the beta-amyloid precursor protein.
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| Johnson RJ, Xiao G, Shanmugaratnam J, Fine RE.
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| Neurobiol Aging. 22(3):387-95. 2001
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| 29 | CALR, HSPA5
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| The measles virus (MV) glycoproteins interact with cellular chaperones in the endoplasmic reticulum and MV infection upregulates chaperone expression.
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| Bolt G.
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| Arch Virol. 146(11):2055-68. 2001
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| 30 | CALR
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| Calreticulin Is a receptor for nuclear export.
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| Holaska JM, Black BE, Love DC, Hanover JA, Leszyk J, Paschal BM.
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| J Cell Biol. 152(1):127-40. 2001
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| 31 | CALR, CANX
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| Functional relationship between calreticulin, calnexin, and the endoplasmic reticulum luminal domain of calnexin.
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| Danilczyk UG, Cohen-Doyle MF, Williams DB.
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| J Biol Chem 275(17):13089-97. 2000
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| 32 | CALR
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| Calreticulin: one protein, one gene, many functions.
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| Michalak M, Corbett EF, Mesaeli N, Nakamura K, Opas M.
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| Biochem J 344 Pt 2:281-92. Review. 1999
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| 33 | CALR
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| Interaction of newly synthesized apolipoprotein B with calnexin and calreticulin requires glucose trimming in the endoplasmic reticulum.
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| Tatu U, Helenius A.
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| Biosci Rep. 19(3):189-96. 1999
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| 34 | CALR
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| Regulation of fibrillin carboxy-terminal furin processing by N-glycosylation, and association of amino- and carboxy-terminal sequences.
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| Ashworth JL, Kelly V, Rock MJ, Shuttleworth CA, Kielty CM.
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| J Cell Sci. 112 ( Pt 22):4163-71. 1999
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| 35 | CALR
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| Calreticulin enhances the transcriptional activity of thyroid transcription factor-1 by binding to its homeodomain.
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| Perrone L, Tell G, Di Lauro R.
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| J Biol Chem. 274(8):4640-5. 1999
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| 36 | ATF6, CALR
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| Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors.
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| Yoshida H, Haze K, Yanagi H, Yura T, Mori K.
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| J Biol Chem 273(50):33741-9. 1998
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| 37 | CALR
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| Differential interaction of coagulation factor VIII and factor V with protein chaperones calnexin and calreticulin.
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| Pipe SW, Morris JA, Shah J, Kaufman RJ.
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| J Biol Chem. 273(14):8537-44. 1998
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| 38 | CALR
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| Interaction between a Ca2+-binding protein calreticulin and perforin, a component of the cytotoxic T-cell granules.
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| Andrin C, Pinkoski MJ, Burns K, Atkinson EA, Krahenbuhl O, Hudig D, Fraser SA, Winkler U, Tschopp J, Opas M, Bleackley RC, Michalak M.
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| Biochemistry. 37(29):10386-94. 1998
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| 39 | CALR
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| Calnexin and calreticulin bind to enzymically active tissue-type plasminogen activator during biosynthesis and are not required for folding to the native conformation.
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| Allen S, Bulleid NJ.
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| Biochem J. 328 ( Pt 1):113-9. 1997
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| 40 | CALR, TAPBP
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| Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP.
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| Sadasivan B, et al.
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| Immunity 5 : 103-114. 1996
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| 41 | CALR
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| Calreticulin interacts with newly synthesized human immunodeficiency virus type 1 envelope glycoprotein, suggesting a chaperone function similar to that of calnexin.
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| Otteken A, Moss B.
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| J Biol Chem. 271(1):97-103. 1996
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| 42 | CALR
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| The glut 1 glucose transporter interacts with calnexin and calreticulin.
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| Oliver JD, Hresko RC, Mueckler M, High S.
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| J Biol Chem. 271(23):13691-6. 1996
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| 43 | CALR
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| Calreticulin binds hYRNA and the 52-kDa polypeptide component of the Ro/SS-A ribonucleoprotein autoantigen.
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| Cheng ST, Nguyen TQ, Yang YS, Capra JD, Sontheimer RD.
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| J Immunol. 156(11):4484-91. 1996
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| 44 | CALR
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| The mitogenic effects of the B beta chain of fibrinogen are mediated through cell surface calreticulin.
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| Gray AJ, Park PW, Broekelmann TJ, Laurent GJ, Reeves JT, Stenmark KR, Mecham RP.
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| J Biol Chem. 270(44):26602-6. 1995
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| 45 | CALR
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| Interaction of calreticulin with protein disulfide isomerase.
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| Baksh S, Burns K, Andrin C, Michalak M.
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| J Biol Chem. 270(52):31338-44. 1995
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| 46 | CALR, RO60
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| Mapping of the human 60000 Mr Ro/SSA locus : the genes for three Ro/SSA autoantigens are located on separate chromosomes.
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| Frank MB, et al.
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| Immunogenetics 39 : 428-431. 1994
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| 47 | CALR
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| Inhibition of nuclear hormone receptor activity by calreticulin.
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| Dedhar S, Rennie PS, Shago M, Hagesteijn CY, Yang H, Filmus J, Hawley RG, Bruchovsky N, Cheng H, Matusik RJ, et al.
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| Nature 367(6462):480-3. 1994
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| 48 | CALR
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| Modulation of gene expression by calreticulin binding to the glucocorticoid receptor.
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| Burns K, Duggan B, Atkinson EA, Famulski KS, Nemer M, Bleackley RC, Michalak M.
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| Nature 367(6462):476-80. 1994
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| 49 | CALR
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| Calreticulin is released from activated neutrophils and binds to C1q and mannan-binding protein.
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| Eggleton P, Lieu TS, Zappi EG, Sastry K, Coburn J, Zaner KS, Sontheimer RD, Capra JD, Ghebrehiwet B, Tauber AI.
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| Clin Immunol Immunopathol. 72(3):405-9. 1994
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| 50 | CALR
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| Inhibition of nuclear hormone receptor activity by calreticulin.
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| Dedhar S, Rennie PS, Shago M, Hagesteijn CY, Yang H, Filmus J, Hawley RG, Bruchovsky N, Cheng H, Matusik RJ, et al.
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| Nature. 367(6462):480-3. 1994
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| 51 | CALR
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| In vitro interaction of a polypeptide homologous to human Ro/SS-A antigen (calreticulin) with a highly conserved amino acid sequence in the cytoplasmic domain of integrin alpha subunits.
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| Rojiani MV, Finlay BB, Gray V, Dedhar S.
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| Biochemistry. 30(41):9859-66. 1991
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| 52 | CALR
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| A human Ro/SS-A autoantigen is the homologue of calreticulin and is highly homologous with onchocercal RAL-1 antigen and an aplysia memory molecule.
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| McCauliffe DP, et al.
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| J Clin Invest 86 : 332-335. 1990
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| 53 | CALR
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| Molecular cloning, expression, and chromosome 19 localization of a human Ro/SS-A autoantigen.
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| McCauliffe DP, et al.
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| J Clin Invest 85 : 1379-1391. 1990
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| 54 | CALR, TRIM21
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| Ro/SS-A and the pathogenic significance of its antibodies.
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| McCauliffe DP, Lux FA, Lieu TS, Sanz I, Hanke J, Newkirk MM, Siciliano MJ, Sontheimer RD, Capra JD.
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| J Autoimmunity 2(4):375-81. 1989
|